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The map label for this gene is rppH

Identifier: 148259912

GI number: 148259912

Start: 994648

End: 995142

Strand: Reverse

Name: rppH

Synonym: Acry_0901

Alternate gene names: 148259912

Gene position: 995142-994648 (Counterclockwise)

Preceding gene: 148259913

Following gene: 148259911

Centisome position: 29.36

GC content: 67.88

Gene sequence:

>495_bases
ATGACCGGCGCGACCGCCCTGCCCTACCGGAGCAATGTCGGCGCCGCGCTGTTCAGTCGCGCGGGCAAGATCCTGGTCGC
GCGCCGGGCCGATCTCGGCCCCGACGCCGCCTATCAGTGGCAGCTGCCGCAGGGCGGGATCGACGGCGACGAAGATCCGG
CCGCCGCCGTGCTGCGCGAGCTGGACGAGGAGATCGGCACCACCGCGGTCGAGCTGCTCGGCGAAATCCCCGAATGGCTC
AGCTATGATTTCCCGCCTGACGTGGTGGCGAAATTCGGCGCGCGGCATCGCGGGCAGCGGCAAAGGTGGTTCGCGCTGCG
CTTTCTCGGCACCGACGACATGATCCGCCTCGACGCCCACGCGCATCCCGAATTCGATGAATGGCGATGGACGGAGCTTT
CCTCCATCCCGGCGCTGGCGGTGCCTTTCAAGCGACCTATTTACGAGCGCCTCGCGCGGGATTTCGCGCGGTTCGCCAAA
ACGGACGGAGCATGA

Upstream 100 bases:

>100_bases
CGGATGACATCGCCGTGCTCGCCCAGTGGTGCCAGGGGCTGAAGGCGGACGGCCTGGTCCTCGTTCCGGTCAGCGCGCTG
GTCGCGGCACGGGGCGCGCA

Downstream 100 bases:

>100_bases
CGATGGGTGAGATGATCAACCTGACCGCCTCCTGCGGGCACAAATTCCAGGCCTATGCCGCCGGCGACACCGCCTCGCAG
CGAGGCATCGTGATCGTGCA

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTGATALPYRSNVGAALFSRAGKILVARRADLGPDAAYQWQLPQGGIDGDEDPAAAVLRELDEEIGTTAVELLGEIPEWL
SYDFPPDVVAKFGARHRGQRQRWFALRFLGTDDMIRLDAHAHPEFDEWRWTELSSIPALAVPFKRPIYERLARDFARFAK
TDGA

Sequences:

>Translated_164_residues
MTGATALPYRSNVGAALFSRAGKILVARRADLGPDAAYQWQLPQGGIDGDEDPAAAVLRELDEEIGTTAVELLGEIPEWL
SYDFPPDVVAKFGARHRGQRQRWFALRFLGTDDMIRLDAHAHPEFDEWRWTELSSIPALAVPFKRPIYERLARDFARFAK
TDGA
>Mature_163_residues
TGATALPYRSNVGAALFSRAGKILVARRADLGPDAAYQWQLPQGGIDGDEDPAAAVLRELDEEIGTTAVELLGEIPEWLS
YDFPPDVVAKFGARHRGQRQRWFALRFLGTDDMIRLDAHAHPEFDEWRWTELSSIPALAVPFKRPIYERLARDFARFAKT
DGA

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=152, Percent_Identity=36.1842105263158, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_ACICJ (A5FWY8)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001234039.1
- ProteinModelPortal:   A5FWY8
- SMR:   A5FWY8
- STRING:   A5FWY8
- GeneID:   5162522
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_0901
- eggNOG:   COG0494
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- ProtClustDB:   PRK00714
- BioCyc:   ACRY349163:ACRY_0901-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 18354; Mature: 18223

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGATALPYRSNVGAALFSRAGKILVARRADLGPDAAYQWQLPQGGIDGDEDPAAAVLRE
CCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHH
LDEEIGTTAVELLGEIPEWLSYDFPPDVVAKFGARHRGQRQRWFALRFLGTDDMIRLDAH
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHEEEEEEECCCCEEEECCC
AHPEFDEWRWTELSSIPALAVPFKRPIYERLARDFARFAKTDGA
CCCCCCCCCCHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGATALPYRSNVGAALFSRAGKILVARRADLGPDAAYQWQLPQGGIDGDEDPAAAVLRE
CCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHH
LDEEIGTTAVELLGEIPEWLSYDFPPDVVAKFGARHRGQRQRWFALRFLGTDDMIRLDAH
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHEEEEEEECCCCEEEECCC
AHPEFDEWRWTELSSIPALAVPFKRPIYERLARDFARFAKTDGA
CCCCCCCCCCHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA