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The map label for this gene is mcpA [H]

Identifier: 148259536

GI number: 148259536

Start: 576780

End: 578690

Strand: Reverse

Name: mcpA [H]

Synonym: Acry_0520

Alternate gene names: 148259536

Gene position: 578690-576780 (Counterclockwise)

Preceding gene: 148259540

Following gene: 148259535

Centisome position: 17.07

GC content: 62.53

Gene sequence:

>1911_bases
GTGCTCAAGAAGCTCTCGATCCGCTATCAGTTCGCCATGCTCGGTGCTTTTGGCGTCGCAATCACTGTCGCGGCGGTGGC
GTTGAACCTGTTCGACTCATACCAGATGGAGTTACACTCTAAGGAAGCCCAGGCCAGAGCACTGGTCGCGAGCGCCGTCA
CCTCGACTGAAACCTATGTCCATCTCGCGGATCAGGGAGTGATCACGAAACAGAAGGCCCAGTCCCTCGCTCTCAAGGCT
CTGGGCGCGGCGCGCTTCGATCACGGCAACTACTTCTTCGTCTACGACCGGCACGGCGTTGCGCTGGCAAATCCGAAAAA
GTCGGTGATCGGGAAAAATCTGGAGAACGTGAAGGATCCATACGGTCATTACGTGATCCGCCCACTGATGCAGGCAGCGG
CGAGCGGTCATCCGATCTTTCATGAATATTATTGGCCGAAAGCGGGATCCTCGACTCCCCAGCCCAAGATTTCCTACATG
GCGGAGGTGCCGGGCTGGCACTGGATGATCGGGTCCGGTCTTTACATCAGTGATCTCAGAACGAATTTCTGGAACGGGGT
GCTGCGTTTCGCCGCGATCTTCATTCCGGTTCTGTTCGCCTTTCTTCTGCTCATGATTTACATGCAGAAAAACATCGCGA
ACATCCTCAAGCGCATGACCTCGGTGATGAAGGCGCTGTCGACGGGCGATTCCAGCGTTGATGTGCCTTTCACCGACCGG
ACCGACGAGATCGGCGGCATGGCGAGCGCGGTCGAGATCTTCAAATCCGCGGGCATCGAGAAGGCGCGGCTGGAAAACGA
TGCCACGGCAGCCGCACGGCAGCGCGAAACCGAGCGTGCTCGTACGGAGGCGGAACGCGCCGCCGCCGCGCAGCAGCTCG
CCACGGTGGTCGATTCTCTCGCCCATGGCCTGGAGGAACTCTCGGCCGGCCGGTTGACGTTCCGACTGACCGCCGCCTTC
GCAGCGGAATACGAACAGCTCCGGACAGACTTCAATGGCGCGATGCAAAGGTTGCAGGACGCGATGCGCGTGGTTGCCAC
AAATGCCTCGGCCATTCGCTCCGGCAGCGGCGAGATCTCCAGCGCTGCGGACGATCTGGCTCGCCGCACCGAGCAGCAAG
CCGCGACCCTCGAGGAAACTGCCGCAGCACTCGACGAAATCACGACGACGGTACGCAATACCGCGGACGCAGCGGTGCAT
GCCCGAAATATCGTCGATACCGCGAAGCAGGACGCCGAGCATGGCGGCTCCGTTGTGTCGCAGGCGGTGCGGGCGATGGG
GGAAATCGAGAACTCATCGAAGCAGATCGGCAACATCATCGGCGTGATCGACGAGATCGCCTTCCAGACCAACCTGCTGG
CGCTGAACGCGGGTGTCGAGGCGGCGCGGGCCGGCGAAGCGGGGCGCGGTTTCGCCGTGGTCGCCTCCGAAGTTCGGGCG
CTGGCGCAGCGCTCGGCCGATGCCGCGAAAGAGATCAAGACACTGATTTCCGCCTCCAACCAGCAGGTTGTCGCGGGCGT
GGACCTTGTTGACGAGACGGGCAAGGCTCTCGAACGGATCGTCCGCCAGATCGCCGAACTCAACGACTCCGTTGCGAAGA
TCGCCGCCTCGGCGCAGGAGCAGTCGACCGGGCTGGTGCAGGTGAATACCGCCGTCAGCCAGATGGATCAGGCAACGCAA
CAGAACGCGGCCATGGTCGAGGAATCAACGGCTGCCAGCCACAGCCTCGTTCAGGAAGCCGAGCAGCTTACCCAGCTGAT
CGGGCGGTTCGATCTGGGCACATCGCCCGCCCCCGCCTCACCGGGCAGACTGCCGGTAACGCCGCCGCGGCCCGCGGCAA
AGCCGGCCCCCTTTGCCGCCCCTAAGCGGCACCTCGAAGGCGCCGATGCCGGCGATTGGGAGGATTTCTGA

Upstream 100 bases:

>100_bases
TCCGGCACGAGAACCGACACGCGCCTCGTATCGATCCCGGATATTCTTTCTTAATCTTTTGCAGGCAAATGAGGCGCTCG
TCGTCGTTGGGAGATTGTTC

Downstream 100 bases:

>100_bases
AGCTGCGACGAACGATCACGGCTGGCCAGGAGGCTTCCGGAATGATCGCCGATGCGCTTCGCCCGCAGCCCCGGCACCGC
GCGTCCGGTGAGTTGGCATG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MLKKLSIRYQFAMLGAFGVAITVAAVALNLFDSYQMELHSKEAQARALVASAVTSTETYVHLADQGVITKQKAQSLALKA
LGAARFDHGNYFFVYDRHGVALANPKKSVIGKNLENVKDPYGHYVIRPLMQAAASGHPIFHEYYWPKAGSSTPQPKISYM
AEVPGWHWMIGSGLYISDLRTNFWNGVLRFAAIFIPVLFAFLLLMIYMQKNIANILKRMTSVMKALSTGDSSVDVPFTDR
TDEIGGMASAVEIFKSAGIEKARLENDATAAARQRETERARTEAERAAAAQQLATVVDSLAHGLEELSAGRLTFRLTAAF
AAEYEQLRTDFNGAMQRLQDAMRVVATNASAIRSGSGEISSAADDLARRTEQQAATLEETAAALDEITTTVRNTADAAVH
ARNIVDTAKQDAEHGGSVVSQAVRAMGEIENSSKQIGNIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRA
LAQRSADAAKEIKTLISASNQQVVAGVDLVDETGKALERIVRQIAELNDSVAKIAASAQEQSTGLVQVNTAVSQMDQATQ
QNAAMVEESTAASHSLVQEAEQLTQLIGRFDLGTSPAPASPGRLPVTPPRPAAKPAPFAAPKRHLEGADAGDWEDF

Sequences:

>Translated_636_residues
MLKKLSIRYQFAMLGAFGVAITVAAVALNLFDSYQMELHSKEAQARALVASAVTSTETYVHLADQGVITKQKAQSLALKA
LGAARFDHGNYFFVYDRHGVALANPKKSVIGKNLENVKDPYGHYVIRPLMQAAASGHPIFHEYYWPKAGSSTPQPKISYM
AEVPGWHWMIGSGLYISDLRTNFWNGVLRFAAIFIPVLFAFLLLMIYMQKNIANILKRMTSVMKALSTGDSSVDVPFTDR
TDEIGGMASAVEIFKSAGIEKARLENDATAAARQRETERARTEAERAAAAQQLATVVDSLAHGLEELSAGRLTFRLTAAF
AAEYEQLRTDFNGAMQRLQDAMRVVATNASAIRSGSGEISSAADDLARRTEQQAATLEETAAALDEITTTVRNTADAAVH
ARNIVDTAKQDAEHGGSVVSQAVRAMGEIENSSKQIGNIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRA
LAQRSADAAKEIKTLISASNQQVVAGVDLVDETGKALERIVRQIAELNDSVAKIAASAQEQSTGLVQVNTAVSQMDQATQ
QNAAMVEESTAASHSLVQEAEQLTQLIGRFDLGTSPAPASPGRLPVTPPRPAAKPAPFAAPKRHLEGADAGDWEDF
>Mature_636_residues
MLKKLSIRYQFAMLGAFGVAITVAAVALNLFDSYQMELHSKEAQARALVASAVTSTETYVHLADQGVITKQKAQSLALKA
LGAARFDHGNYFFVYDRHGVALANPKKSVIGKNLENVKDPYGHYVIRPLMQAAASGHPIFHEYYWPKAGSSTPQPKISYM
AEVPGWHWMIGSGLYISDLRTNFWNGVLRFAAIFIPVLFAFLLLMIYMQKNIANILKRMTSVMKALSTGDSSVDVPFTDR
TDEIGGMASAVEIFKSAGIEKARLENDATAAARQRETERARTEAERAAAAQQLATVVDSLAHGLEELSAGRLTFRLTAAF
AAEYEQLRTDFNGAMQRLQDAMRVVATNASAIRSGSGEISSAADDLARRTEQQAATLEETAAALDEITTTVRNTADAAVH
ARNIVDTAKQDAEHGGSVVSQAVRAMGEIENSSKQIGNIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRA
LAQRSADAAKEIKTLISASNQQVVAGVDLVDETGKALERIVRQIAELNDSVAKIAASAQEQSTGLVQVNTAVSQMDQATQ
QNAAMVEESTAASHSLVQEAEQLTQLIGRFDLGTSPAPASPGRLPVTPPRPAAKPAPFAAPKRHLEGADAGDWEDF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=337, Percent_Identity=45.9940652818991, Blast_Score=242, Evalue=6e-65,
Organism=Escherichia coli, GI1787690, Length=327, Percent_Identity=44.3425076452599, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI2367378, Length=341, Percent_Identity=42.8152492668622, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI1788194, Length=266, Percent_Identity=47.7443609022556, Blast_Score=209, Evalue=6e-55,
Organism=Escherichia coli, GI1789453, Length=239, Percent_Identity=39.7489539748954, Blast_Score=169, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68169; Mature: 68169

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKLSIRYQFAMLGAFGVAITVAAVALNLFDSYQMELHSKEAQARALVASAVTSTETYV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
HLADQGVITKQKAQSLALKALGAARFDHGNYFFVYDRHGVALANPKKSVIGKNLENVKDP
EECCCCCHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCEEECCCHHHHHCCCHHHHCCH
YGHYVIRPLMQAAASGHPIFHEYYWPKAGSSTPQPKISYMAEVPGWHWMIGSGLYISDLR
HHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCEEHHHHH
TNFWNGVLRFAAIFIPVLFAFLLLMIYMQKNIANILKRMTSVMKALSTGDSSVDVPFTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TDEIGGMASAVEIFKSAGIEKARLENDATAAARQRETERARTEAERAAAAQQLATVVDSL
CHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHGLEELSAGRLTFRLTAAFAAEYEQLRTDFNGAMQRLQDAMRVVATNASAIRSGSGEIS
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHH
SAADDLARRTEQQAATLEETAAALDEITTTVRNTADAAVHARNIVDTAKQDAEHGGSVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
QAVRAMGEIENSSKQIGNIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHH
LAQRSADAAKEIKTLISASNQQVVAGVDLVDETGKALERIVRQIAELNDSVAKIAASAQE
HHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSTGLVQVNTAVSQMDQATQQNAAMVEESTAASHSLVQEAEQLTQLIGRFDLGTSPAPAS
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PGRLPVTPPRPAAKPAPFAAPKRHLEGADAGDWEDF
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLKKLSIRYQFAMLGAFGVAITVAAVALNLFDSYQMELHSKEAQARALVASAVTSTETYV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
HLADQGVITKQKAQSLALKALGAARFDHGNYFFVYDRHGVALANPKKSVIGKNLENVKDP
EECCCCCHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCEEECCCHHHHHCCCHHHHCCH
YGHYVIRPLMQAAASGHPIFHEYYWPKAGSSTPQPKISYMAEVPGWHWMIGSGLYISDLR
HHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCEEHHHHH
TNFWNGVLRFAAIFIPVLFAFLLLMIYMQKNIANILKRMTSVMKALSTGDSSVDVPFTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TDEIGGMASAVEIFKSAGIEKARLENDATAAARQRETERARTEAERAAAAQQLATVVDSL
CHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHGLEELSAGRLTFRLTAAFAAEYEQLRTDFNGAMQRLQDAMRVVATNASAIRSGSGEIS
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHH
SAADDLARRTEQQAATLEETAAALDEITTTVRNTADAAVHARNIVDTAKQDAEHGGSVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
QAVRAMGEIENSSKQIGNIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHH
LAQRSADAAKEIKTLISASNQQVVAGVDLVDETGKALERIVRQIAELNDSVAKIAASAQE
HHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSTGLVQVNTAVSQMDQATQQNAAMVEESTAASHSLVQEAEQLTQLIGRFDLGTSPAPAS
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PGRLPVTPPRPAAKPAPFAAPKRHLEGADAGDWEDF
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]