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The map label for this gene is ag45 [H]

Identifier: 148259324

GI number: 148259324

Start: 351774

End: 353018

Strand: Reverse

Name: ag45 [H]

Synonym: Acry_0305

Alternate gene names: 148259324

Gene position: 353018-351774 (Counterclockwise)

Preceding gene: 148259325

Following gene: 148259323

Centisome position: 10.42

GC content: 72.13

Gene sequence:

>1245_bases
ATGCACGGCGACCTCTTCGGATCATGGCAGCCGGCCGCGACGGTGGTCATCTTCGCGCTGACCTACGCCGGGGTGGCGCT
GGGCCGGTTGCCCTTCTTCCGGCTCGACCGCGCGGGGATCGCCTTCGTCGGCGCGGTGCTGATGGTCGCGAGCGGGGCGC
TGACGCTCCGGCAGGCGGTCGCCGCGATCGATTTCGACACGATCGCGCTGCTGCTCGGCATGATGATCCTCGCCGCGGCG
CTGCGCCGGGCCGGGTTCTTCGAGCGGATCACCGGGGCGGTGCTCTCGCGCGCCTCCGGCACCGATGCGCTGCTGGCGCT
CACCGTCGCGATGGCCGGGCTGCTCTCGGCGGTGCTGGTCAACGACACGGTCTGCGTCGTGCTCACGCCGCTGGTGCTCG
AAGCCTGCCGGGCGGGGCGGAAACAGCCCCTGCCCTATCTCGTCGCGCTGGCGACCGCCTCGAATGTCGGGTCGGTGGCG
ACGATCACCGGCAACCCGCAGAACATGATCATCGGCAGCCTCTCCGGCATCGGCTATGCCGCGTTCGCCGGCGCGCTGGT
GCCGGTCGCGCTGCTCGGGCTGCCGATCGTCTTCCTCGTCATCCGGCTGCTGCATCGCGCGGGCTTCGAGGCGCTGACGG
CGCCGGCGGCATCCGCCGCGCGGCGCCGGCCGCATGGCGGGCTCATCGGCAAGTCGGTCGTGCTGCTGGTGCTGTTCGTC
ATCGCCTGCCTCGGCGGCATGCGCCCGGCGGAGGCGGCGCTGGTGGCCGCCGCGCTGATCATGCTGACGCCGGGGGTGAA
GAGCCAGCGCCTGCTCGCCGGCGTCGACTGGTCGCTGCTGCTGATGTTCGCGGGGCTGTTCGTCGTCGTTGCCGCGTTGC
AGCGCGAGGTGATCGGCGCGGCGGTGATCGGGCGCGTCGCAGCCCTGCATCCGGGCCGGCCGGCGGTGCTGGTGCCGCTC
ACCGCGATCCTGTCGAACCTGGTCAGCAACGTGCCGGCGGTGCTGGTGCTGCGCCCCTTCATCGCCCATCTCGCCGACCC
GCGGCAGGCGTGGCTCATCGTCGCCATGGCATCCACCCTCGCGGGCAACCTGACGCTGCCGGGATCGGTGGCGAATCTCA
TCGTCGCCGAGCGGGCGCGCGCCGCCGGCGTGCGGATCGGCTTCGGCGACTATCTGAAGTTCGGCCTGCCCATCACGGTT
CTCACGATCGCGCTCGGCACCGCCTGGCTCGTCGGCATCGGCTAG

Upstream 100 bases:

>100_bases
AGATGCAGGATTCGATACGGGCGGGCACGGCCGGGGCAGCGACGCGGCCGGCAGGCGGCGTACCTTCTCCGCCGCGGCCG
CTGAGCGCAAGGTCCGCGCC

Downstream 100 bases:

>100_bases
GTGGTTCGGGGCGGATTGACAGCCCGGACCCGGCATCGCAAACACGTCCCGTGCGGTCCGGCCGCGCCGGCGATGGGGTT
CGCCGTGAACCGCCCGCGGG

Product: citrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MHGDLFGSWQPAATVVIFALTYAGVALGRLPFFRLDRAGIAFVGAVLMVASGALTLRQAVAAIDFDTIALLLGMMILAAA
LRRAGFFERITGAVLSRASGTDALLALTVAMAGLLSAVLVNDTVCVVLTPLVLEACRAGRKQPLPYLVALATASNVGSVA
TITGNPQNMIIGSLSGIGYAAFAGALVPVALLGLPIVFLVIRLLHRAGFEALTAPAASAARRRPHGGLIGKSVVLLVLFV
IACLGGMRPAEAALVAAALIMLTPGVKSQRLLAGVDWSLLLMFAGLFVVVAALQREVIGAAVIGRVAALHPGRPAVLVPL
TAILSNLVSNVPAVLVLRPFIAHLADPRQAWLIVAMASTLAGNLTLPGSVANLIVAERARAAGVRIGFGDYLKFGLPITV
LTIALGTAWLVGIG

Sequences:

>Translated_414_residues
MHGDLFGSWQPAATVVIFALTYAGVALGRLPFFRLDRAGIAFVGAVLMVASGALTLRQAVAAIDFDTIALLLGMMILAAA
LRRAGFFERITGAVLSRASGTDALLALTVAMAGLLSAVLVNDTVCVVLTPLVLEACRAGRKQPLPYLVALATASNVGSVA
TITGNPQNMIIGSLSGIGYAAFAGALVPVALLGLPIVFLVIRLLHRAGFEALTAPAASAARRRPHGGLIGKSVVLLVLFV
IACLGGMRPAEAALVAAALIMLTPGVKSQRLLAGVDWSLLLMFAGLFVVVAALQREVIGAAVIGRVAALHPGRPAVLVPL
TAILSNLVSNVPAVLVLRPFIAHLADPRQAWLIVAMASTLAGNLTLPGSVANLIVAERARAAGVRIGFGDYLKFGLPITV
LTIALGTAWLVGIG
>Mature_414_residues
MHGDLFGSWQPAATVVIFALTYAGVALGRLPFFRLDRAGIAFVGAVLMVASGALTLRQAVAAIDFDTIALLLGMMILAAA
LRRAGFFERITGAVLSRASGTDALLALTVAMAGLLSAVLVNDTVCVVLTPLVLEACRAGRKQPLPYLVALATASNVGSVA
TITGNPQNMIIGSLSGIGYAAFAGALVPVALLGLPIVFLVIRLLHRAGFEALTAPAASAARRRPHGGLIGKSVVLLVLFV
IACLGGMRPAEAALVAAALIMLTPGVKSQRLLAGVDWSLLLMFAGLFVVVAALQREVIGAAVIGRVAALHPGRPAVLVPL
TAILSNLVSNVPAVLVLRPFIAHLADPRQAWLIVAMASTLAGNLTLPGSVANLIVAERARAAGVRIGFGDYLKFGLPITV
LTIALGTAWLVGIG

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=158, Percent_Identity=34.1772151898734, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787039, Length=333, Percent_Identity=29.4294294294294, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI85724998, Length=447, Percent_Identity=22.5950782997763, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62484377, Length=447, Percent_Identity=22.5950782997763, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574683, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574681, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574685, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574678, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581759, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920704, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 42490; Mature: 42490

Theoretical pI: Translated: 11.58; Mature: 11.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGDLFGSWQPAATVVIFALTYAGVALGRLPFFRLDRAGIAFVGAVLMVASGALTLRQAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
AAIDFDTIALLLGMMILAAALRRAGFFERITGAVLSRASGTDALLALTVAMAGLLSAVLV
HHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
NDTVCVVLTPLVLEACRAGRKQPLPYLVALATASNVGSVATITGNPQNMIIGSLSGIGYA
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCHHH
AFAGALVPVALLGLPIVFLVIRLLHRAGFEALTAPAASAARRRPHGGLIGKSVVLLVLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHH
IACLGGMRPAEAALVAAALIMLTPGVKSQRLLAGVDWSLLLMFAGLFVVVAALQREVIGA
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVIGRVAALHPGRPAVLVPLTAILSNLVSNVPAVLVLRPFIAHLADPRQAWLIVAMASTL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AGNLTLPGSVANLIVAERARAAGVRIGFGDYLKFGLPITVLTIALGTAWLVGIG
CCCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHGDLFGSWQPAATVVIFALTYAGVALGRLPFFRLDRAGIAFVGAVLMVASGALTLRQAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
AAIDFDTIALLLGMMILAAALRRAGFFERITGAVLSRASGTDALLALTVAMAGLLSAVLV
HHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
NDTVCVVLTPLVLEACRAGRKQPLPYLVALATASNVGSVATITGNPQNMIIGSLSGIGYA
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCHHH
AFAGALVPVALLGLPIVFLVIRLLHRAGFEALTAPAASAARRRPHGGLIGKSVVLLVLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHH
IACLGGMRPAEAALVAAALIMLTPGVKSQRLLAGVDWSLLLMFAGLFVVVAALQREVIGA
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVIGRVAALHPGRPAVLVPLTAILSNLVSNVPAVLVLRPFIAHLADPRQAWLIVAMASTL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AGNLTLPGSVANLIVAERARAAGVRIGFGDYLKFGLPITVLTIALGTAWLVGIG
CCCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]