Click here to switch to the map view.

The map label for this gene is 148259282

Identifier: 148259282

GI number: 148259282

Start: 302070

End: 302897

Strand: Reverse

Name: 148259282

Synonym: Acry_0262

Alternate gene names: NA

Gene position: 302897-302070 (Counterclockwise)

Preceding gene: 148259287

Following gene: 148259281

Centisome position: 8.94

GC content: 72.46

Gene sequence:

>828_bases
ATGCCGGTCATGACGACGATCGCATATCTTCCCGCGCGCGGCGTGATCGGGATCGAGGGGCCCGACCGCGTCGCCTTCCT
CCAGGGCCTCGTGTCGAACGACGTGACGAAGGCGGAACCGGGCCGGGCCGTCTGGTCCGCGCTGCTGACGCCGCAGGGGC
GCTACCTGGCCGAGTTCTTCATTCTCACCGACGGCGAGTCGCTCCTGCTGGATGCGCCGGGCGTGGCGGTTCCGGACCTG
ATCCGCCGGCTGTCGCGCTTCCGGCTGCGCAGCCAGGTGGCGCTGCGCGACCGGTCGGACGAATTCGCGGTGCATGCCGC
ATGGGGCGGCGCGCCGTCCGCCCCCGGCGCGATCGTCGCCGCCGACCCGCGCCTGCCCGCAGCCGGCCACAGGCTCCTCG
CGCCGGCGCCGCTGGCCGGAGCGGCGGATGAAACCGCCTATCGCGCGCACCGGCTGGCGCTCGGCCTGCCCGACCATGAC
GATCTCGAACCGGAAAAGACCCTGCTGATGGAAGCCGGCTTCGGCGATCTGCACGGGATCGACTGGGACAAGGGCTGCTA
CATGGGGCAGGAACTCACCGCCCGCACCCGCTACCGGGGGCTGGTGAAGCGCCGGCTCGTCCCGGTCGATGCCGAAGCGG
ACCTGCCCGCCGCCGGGGCGATCACCGCCGGTGAGCGCGAAGTGGGCACGCTGCGGACGAGCCTCGGCCGGCGCGGCCTC
GCGCTGCTGCGGCTCGATGCGCTGGATGCCAGGCTGAGTCTCGACGGCATCGCGCTGACGCCCGACATTCCATCCTGGAT
GACCCTGCCGGAGACCGCGACCCCATGA

Upstream 100 bases:

>100_bases
AGGAAATCACCGCGTCGCCGATGCGGGACGAGGCTATGAACAGGATTCTCATGCTGCGGTGGCTGTAGCACGGCTTGCCG
CCGCACGGCCAAGGGGCCAC

Downstream 100 bases:

>100_bases
TCGTCGTTCATCATCTCGAAGCGTCGCGCTCGCAGCGCGTGCTCTGGCTGCTCGAGGAACTCGGCCTCGAATACGAGGTG
CAGCGCTATGACCGCGACCG

Product: glycine cleavage T-protein, C-terminal barrel

Products: protein-dihydrolipoyllysine; 5,10-methylenetetrahydrofolate; NH3

Alternate protein names: Aminomethyltransferase; Aminomethyltransferase Family Protein; Aminomethyl Transferase Family Protein; Aminomethyltransferase Related GcvT; Glycine Cleavage T-Protein C-Terminal Barrel; Aminomethyl Transferase

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MPVMTTIAYLPARGVIGIEGPDRVAFLQGLVSNDVTKAEPGRAVWSALLTPQGRYLAEFFILTDGESLLLDAPGVAVPDL
IRRLSRFRLRSQVALRDRSDEFAVHAAWGGAPSAPGAIVAADPRLPAAGHRLLAPAPLAGAADETAYRAHRLALGLPDHD
DLEPEKTLLMEAGFGDLHGIDWDKGCYMGQELTARTRYRGLVKRRLVPVDAEADLPAAGAITAGEREVGTLRTSLGRRGL
ALLRLDALDARLSLDGIALTPDIPSWMTLPETATP

Sequences:

>Translated_275_residues
MPVMTTIAYLPARGVIGIEGPDRVAFLQGLVSNDVTKAEPGRAVWSALLTPQGRYLAEFFILTDGESLLLDAPGVAVPDL
IRRLSRFRLRSQVALRDRSDEFAVHAAWGGAPSAPGAIVAADPRLPAAGHRLLAPAPLAGAADETAYRAHRLALGLPDHD
DLEPEKTLLMEAGFGDLHGIDWDKGCYMGQELTARTRYRGLVKRRLVPVDAEADLPAAGAITAGEREVGTLRTSLGRRGL
ALLRLDALDARLSLDGIALTPDIPSWMTLPETATP
>Mature_274_residues
PVMTTIAYLPARGVIGIEGPDRVAFLQGLVSNDVTKAEPGRAVWSALLTPQGRYLAEFFILTDGESLLLDAPGVAVPDLI
RRLSRFRLRSQVALRDRSDEFAVHAAWGGAPSAPGAIVAADPRLPAAGHRLLAPAPLAGAADETAYRAHRLALGLPDHDD
LEPEKTLLMEAGFGDLHGIDWDKGCYMGQELTARTRYRGLVKRRLVPVDAEADLPAAGAITAGEREVGTLRTSLGRRGLA
LLRLDALDARLSLDGIALTPDIPSWMTLPETATP

Specific function: Unknown

COG id: COG0354

COG function: function code R; Predicted aminomethyltransferase related to GcvT

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI58197556, Length=299, Percent_Identity=30.1003344481605, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71985951, Length=262, Percent_Identity=29.7709923664122, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24645123, Length=295, Percent_Identity=29.1525423728814, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.2.10

Molecular weight: Translated: 29402; Mature: 29271

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVMTTIAYLPARGVIGIEGPDRVAFLQGLVSNDVTKAEPGRAVWSALLTPQGRYLAEFF
CCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEE
ILTDGESLLLDAPGVAVPDLIRRLSRFRLRSQVALRDRSDEFAVHAAWGGAPSAPGAIVA
EEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEE
ADPRLPAAGHRLLAPAPLAGAADETAYRAHRLALGLPDHDDLEPEKTLLMEAGFGDLHGI
ECCCCCCCCCEEECCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCEEEEECCCCCCCCC
DWDKGCYMGQELTARTRYRGLVKRRLVPVDAEADLPAAGAITAGEREVGTLRTSLGRRGL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCCE
ALLRLDALDARLSLDGIALTPDIPSWMTLPETATP
EEEEEEHHCCEEECCCEEECCCCCCCEECCCCCCC
>Mature Secondary Structure 
PVMTTIAYLPARGVIGIEGPDRVAFLQGLVSNDVTKAEPGRAVWSALLTPQGRYLAEFF
CHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEE
ILTDGESLLLDAPGVAVPDLIRRLSRFRLRSQVALRDRSDEFAVHAAWGGAPSAPGAIVA
EEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEE
ADPRLPAAGHRLLAPAPLAGAADETAYRAHRLALGLPDHDDLEPEKTLLMEAGFGDLHGI
ECCCCCCCCCEEECCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCEEEEECCCCCCCCC
DWDKGCYMGQELTARTRYRGLVKRRLVPVDAEADLPAAGAITAGEREVGTLRTSLGRRGL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCCE
ALLRLDALDARLSLDGIALTPDIPSWMTLPETATP
EEEEEEHHCCEEECCCEEECCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein-S-aminomethyldihydrolipoyllysine; tetrahydrofolate

Specific reaction: protein-S-aminomethyldihydrolipoyllysine + tetrahydrofolate = protein-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA