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The map label for this gene is hpsA [H]

Identifier: 148259218

GI number: 148259218

Start: 228858

End: 229571

Strand: Reverse

Name: hpsA [H]

Synonym: Acry_0198

Alternate gene names: 148259218

Gene position: 229571-228858 (Counterclockwise)

Preceding gene: 148259220

Following gene: 148259215

Centisome position: 6.77

GC content: 68.49

Gene sequence:

>714_bases
ATGCTCAAGCCGGATACGCGCGAAAAACTCACCCGTGTCAGCACGGCGACCCTGGCCACCGCGCTCTACAAGCGCGGCCT
GCGCCAGCAGTTCATCCAGGGCGCGCTGCCGCTGAGCCCGCCGGAACGGAGCATGGTCGGCGAGGCCTTTACCCTGCGCT
ACATTCCAGCGCGCGAAGACCTCAACCCGATCACCGTCTTCCGCGATCGCGATCACAAGCAGCGCCAGGCGATCGAGACC
TGCCCGCCCGGCGCGGTGATGGTAATCGACAGCCGCAAGGATGCCCGCGCCGCCTCGGCCGGCGGCATTCTCGTCACCAG
GCTGATGCAGCGGGGCGCTGCCGGCATCGTCACCGATGGCGGCTTTCGCGACAGCGCCGAAATCGCCGCGCTCGGCTTCC
CTGCCTATCACGTGCGTCCCAGCGCGCCGACCAATCTCACCCTGCACCAGGCCATCGCCATCAACGACCCGATCAGCTGC
GGCGACGCGCCGGTCTTCCCTGGCGACGTGATCGTGGGCGACGCCGACGGCGCCATCGTGATTCCCGCCCACCTCGCCGA
CGAACTCGCCGACGAGGCTACGGAGATGACGGTCTTCGAGGATTTCGTGACCGAGCAGGTGAAGGCCGGCGCGACGATCC
TCGGCCTCTATCCGCCGACCGATCCGGAAACCGAAACCCGTTTCGCCGCCTGGCGCGCCCGCACGGGCCGCTGA

Upstream 100 bases:

>100_bases
CCACCACCACGACACGCGGGCGGCAATCCCGCCAGCCGGCGCTGTCGTCCAGCAACATGGGCCGGGAAACCTGCACCTTC
CGGCCGGCAGCGAGGAACCG

Downstream 100 bases:

>100_bases
CCGCGGCCCGGTGGACGGTAGGTATGCCTCAGTCCCGCATCACGCCGTCGACAAGCCGCGGCATGGCGAGCGGATTGCCG
TCCGCCAGCGCCGTCGGCAG

Product: hypothetical protein

Products: NA

Alternate protein names: HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MLKPDTREKLTRVSTATLATALYKRGLRQQFIQGALPLSPPERSMVGEAFTLRYIPAREDLNPITVFRDRDHKQRQAIET
CPPGAVMVIDSRKDARAASAGGILVTRLMQRGAAGIVTDGGFRDSAEIAALGFPAYHVRPSAPTNLTLHQAIAINDPISC
GDAPVFPGDVIVGDADGAIVIPAHLADELADEATEMTVFEDFVTEQVKAGATILGLYPPTDPETETRFAAWRARTGR

Sequences:

>Translated_237_residues
MLKPDTREKLTRVSTATLATALYKRGLRQQFIQGALPLSPPERSMVGEAFTLRYIPAREDLNPITVFRDRDHKQRQAIET
CPPGAVMVIDSRKDARAASAGGILVTRLMQRGAAGIVTDGGFRDSAEIAALGFPAYHVRPSAPTNLTLHQAIAINDPISC
GDAPVFPGDVIVGDADGAIVIPAHLADELADEATEMTVFEDFVTEQVKAGATILGLYPPTDPETETRFAAWRARTGR
>Mature_237_residues
MLKPDTREKLTRVSTATLATALYKRGLRQQFIQGALPLSPPERSMVGEAFTLRYIPAREDLNPITVFRDRDHKQRQAIET
CPPGAVMVIDSRKDARAASAGGILVTRLMQRGAAGIVTDGGFRDSAEIAALGFPAYHVRPSAPTNLTLHQAIAINDPISC
GDAPVFPGDVIVGDADGAIVIPAHLADELADEATEMTVFEDFVTEQVKAGATILGLYPPTDPETETRFAAWRARTGR

Specific function: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate [H]

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017120
- InterPro:   IPR001754
- InterPro:   IPR011060
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 25548; Mature: 25548

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPDTREKLTRVSTATLATALYKRGLRQQFIQGALPLSPPERSMVGEAFTLRYIPARED
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEEEEECCCCC
LNPITVFRDRDHKQRQAIETCPPGAVMVIDSRKDARAASAGGILVTRLMQRGAAGIVTDG
CCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHHHHHHHCCCCEEEECC
GFRDSAEIAALGFPAYHVRPSAPTNLTLHQAIAINDPISCGDAPVFPGDVIVGDADGAIV
CCCCCCCEEEECCCCEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEE
IPAHLADELADEATEMTVFEDFVTEQVKAGATILGLYPPTDPETETRFAAWRARTGR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MLKPDTREKLTRVSTATLATALYKRGLRQQFIQGALPLSPPERSMVGEAFTLRYIPARED
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEEEEECCCCC
LNPITVFRDRDHKQRQAIETCPPGAVMVIDSRKDARAASAGGILVTRLMQRGAAGIVTDG
CCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHHHHHHHCCCCEEEECC
GFRDSAEIAALGFPAYHVRPSAPTNLTLHQAIAINDPISCGDAPVFPGDVIVGDADGAIV
CCCCCCCEEEECCCCEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEE
IPAHLADELADEATEMTVFEDFVTEQVKAGATILGLYPPTDPETETRFAAWRARTGR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA