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The map label for this gene is degA [H]

Identifier: 148259206

GI number: 148259206

Start: 212360

End: 213367

Strand: Reverse

Name: degA [H]

Synonym: Acry_0186

Alternate gene names: 148259206

Gene position: 213367-212360 (Counterclockwise)

Preceding gene: 148259212

Following gene: 148259202

Centisome position: 6.3

GC content: 70.34

Gene sequence:

>1008_bases
ATGGCCGTCAGTATCAAGGATGTGGCCCGTGCCGCAGGGGTTTCGCCCGCCACGGTCTCGCGCACGCTCGGCGGCGGCCC
CGTCAGTGCGGCGCTGCGCGACAAGGTCGAGGAGGCAGTGCGCCGCACCGGCTACCGGCCCAACCTGTCCGCCCGCCGCC
TTCGCTCGCAGGAGTCGCAGACGGTCGGGCTGATTGTCGCCGATATCTCGAACCCCTTCTTCACCGCCGTCGCCCGCGCC
GTCGAGCACGCCGCCTACCGCGCCGGCCTGCGCGTCATCCTGTGCAATACCGACGAGAACCCCGAGAAGGAAGCGATGTA
TCTCCAGCTCATGGAGCAGGAGCGCGTCACCGGGGTGATCTTCGCGCCGACCCGCGCCTCGGTGGAGCGGCTCGACCAGG
GGCCGCGCCCGTCCTTTCCGATGGTGCTGATCGACCGCGCCGGCCGCGCCAGCGCGCAGGATGCCGTGGTGCTCGACAAT
TTCGCCGCCGGCTCGATGCTGGTCGAACACCTTGCCGGCCAGGGCTACCGGCGCATCGCCGGGCTGTTCGGCAATGCCAG
CACCACCGGCGTGGAACGGCGCGACGGCTACGAGGCGGCGATGCTCCGCGCCGGGCTCTCGCCGTCGTCGCGCTTCATCG
CCCCCAGCATCGAGGCTGCCGAGCAGGAAATCGCCCGCTGGTTCGCAAAGGGCAACCTGCCCGAGGCGGTGATCGCCAGC
AATGGCCTGCTGCTGATGGGCGTGGTCCGCGCCCTGCGCGCCACCGGCCGGCGCATGCCGGAGGATCTCGCGATCGCCGG
TTTCGACAATGAAAGCTGGACCGACCTCGTCGGTCCGGGCATCACCGTCATCGAACAGCCGGTGGCACAGATCGGCGAGG
AGGCGATGCGCCTTCTGCTCGAAAGGCTCGATGCGCCCGAAGCCCCGGTGCGCAAGACCGTGCTCGGCGGGCGCTGCGTC
ATCCGCGGCTCAACCGCCCGCCGCGCTCTGGACGAAGCCGCCGAATAA

Upstream 100 bases:

>100_bases
CCTGCTGATTTTTCCTTGCGGAAACAGCCAGTTTCATGCTCAGTTTCTGAGAACGATTTCCAGAATTTTTTCTCTGGCAG
GCACGAAAGACAACGCCCCG

Downstream 100 bases:

>100_bases
GGCTTACGCCCGGCCCGTCAGCCGCATTTCGACCAGCCGCAATGCAGGCAGCTCAGGCAGCCCGCCTCGCGCACCAGGCC
GGGCTGGCTGCATTTCGGGC

Product: alanine racemase

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVSIKDVARAAGVSPATVSRTLGGGPVSAALRDKVEEAVRRTGYRPNLSARRLRSQESQTVGLIVADISNPFFTAVARA
VEHAAYRAGLRVILCNTDENPEKEAMYLQLMEQERVTGVIFAPTRASVERLDQGPRPSFPMVLIDRAGRASAQDAVVLDN
FAAGSMLVEHLAGQGYRRIAGLFGNASTTGVERRDGYEAAMLRAGLSPSSRFIAPSIEAAEQEIARWFAKGNLPEAVIAS
NGLLLMGVVRALRATGRRMPEDLAIAGFDNESWTDLVGPGITVIEQPVAQIGEEAMRLLLERLDAPEAPVRKTVLGGRCV
IRGSTARRALDEAAE

Sequences:

>Translated_335_residues
MAVSIKDVARAAGVSPATVSRTLGGGPVSAALRDKVEEAVRRTGYRPNLSARRLRSQESQTVGLIVADISNPFFTAVARA
VEHAAYRAGLRVILCNTDENPEKEAMYLQLMEQERVTGVIFAPTRASVERLDQGPRPSFPMVLIDRAGRASAQDAVVLDN
FAAGSMLVEHLAGQGYRRIAGLFGNASTTGVERRDGYEAAMLRAGLSPSSRFIAPSIEAAEQEIARWFAKGNLPEAVIAS
NGLLLMGVVRALRATGRRMPEDLAIAGFDNESWTDLVGPGITVIEQPVAQIGEEAMRLLLERLDAPEAPVRKTVLGGRCV
IRGSTARRALDEAAE
>Mature_334_residues
AVSIKDVARAAGVSPATVSRTLGGGPVSAALRDKVEEAVRRTGYRPNLSARRLRSQESQTVGLIVADISNPFFTAVARAV
EHAAYRAGLRVILCNTDENPEKEAMYLQLMEQERVTGVIFAPTRASVERLDQGPRPSFPMVLIDRAGRASAQDAVVLDNF
AAGSMLVEHLAGQGYRRIAGLFGNASTTGVERRDGYEAAMLRAGLSPSSRFIAPSIEAAEQEIARWFAKGNLPEAVIASN
GLLLMGVVRALRATGRRMPEDLAIAGFDNESWTDLVGPGITVIEQPVAQIGEEAMRLLLERLDAPEAPVRKTVLGGRCVI
RGSTARRALDEAAE

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=338, Percent_Identity=32.2485207100592, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=29.8192771084337, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789202, Length=337, Percent_Identity=30.8605341246291, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1788474, Length=307, Percent_Identity=31.9218241042345, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1789068, Length=332, Percent_Identity=28.9156626506024, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787948, Length=312, Percent_Identity=29.8076923076923, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787580, Length=326, Percent_Identity=28.5276073619632, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787906, Length=333, Percent_Identity=29.1291291291291, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI48994940, Length=303, Percent_Identity=28.3828382838284, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786268, Length=320, Percent_Identity=27.1875, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786540, Length=305, Percent_Identity=25.2459016393443, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790689, Length=312, Percent_Identity=24.6794871794872, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790715, Length=328, Percent_Identity=22.2560975609756, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789456, Length=326, Percent_Identity=22.6993865030675, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35931; Mature: 35799

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSIKDVARAAGVSPATVSRTLGGGPVSAALRDKVEEAVRRTGYRPNLSARRLRSQESQ
CCCCHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
TVGLIVADISNPFFTAVARAVEHAAYRAGLRVILCNTDENPEKEAMYLQLMEQERVTGVI
EEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
FAPTRASVERLDQGPRPSFPMVLIDRAGRASAQDAVVLDNFAAGSMLVEHLAGQGYRRIA
ECCCHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHCCCHHHHH
GLFGNASTTGVERRDGYEAAMLRAGLSPSSRFIAPSIEAAEQEIARWFAKGNLPEAVIAS
HHHCCCCCCCCCHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHC
NGLLLMGVVRALRATGRRMPEDLAIAGFDNESWTDLVGPGITVIEQPVAQIGEEAMRLLL
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ERLDAPEAPVRKTVLGGRCVIRGSTARRALDEAAE
HHCCCCCCCHHHHHCCCEEEEECCHHHHHHHHHCC
>Mature Secondary Structure 
AVSIKDVARAAGVSPATVSRTLGGGPVSAALRDKVEEAVRRTGYRPNLSARRLRSQESQ
CCCHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
TVGLIVADISNPFFTAVARAVEHAAYRAGLRVILCNTDENPEKEAMYLQLMEQERVTGVI
EEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
FAPTRASVERLDQGPRPSFPMVLIDRAGRASAQDAVVLDNFAAGSMLVEHLAGQGYRRIA
ECCCHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHCCCHHHHH
GLFGNASTTGVERRDGYEAAMLRAGLSPSSRFIAPSIEAAEQEIARWFAKGNLPEAVIAS
HHHCCCCCCCCCHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHC
NGLLLMGVVRALRATGRRMPEDLAIAGFDNESWTDLVGPGITVIEQPVAQIGEEAMRLLL
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ERLDAPEAPVRKTVLGGRCVIRGSTARRALDEAAE
HHCCCCCCCHHHHHCCCEEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]