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The map label for this gene is hmrR2 [H]

Identifier: 148259110

GI number: 148259110

Start: 97812

End: 98225

Strand: Reverse

Name: hmrR2 [H]

Synonym: Acry_0089

Alternate gene names: 148259110

Gene position: 98225-97812 (Counterclockwise)

Preceding gene: 148259111

Following gene: 148259109

Centisome position: 2.9

GC content: 62.8

Gene sequence:

>414_bases
ATGACCCGGACGGAGATCACGATCGGCGAGGCCGCGGCGCGGAGCGGCGTTTCGGCCAAGATGATCCGCCATTACGAACG
GATCGGCCTGATCACGCCGCCGCTGCGCGGCGAAGCCAACAATTACCGTTTTTACGATGAGCGGTTGGTGCACGAGCTGC
GCTTCATTCACCGCGCCCGTGACCTCGGCTTTGCCATCGTCGATATCCGGGCATTGCTTTCGCTCTGGCGCGACCGTAAC
CGCCCCTCTCGCGACGTGAAGGCCATCGCCGTTGCCCATATCGCCGAACTCGAGGCGAAAGCAGCGGCGCTACATTCCAT
GAGCGCGGAGCTGAGGCGCCTCGTTGAAAGCTGCCATGGCAGTGACAGGCCGGACTGCCCCATTCTCGAAGAACTGGCAA
ACCCCGGAAGTTGA

Upstream 100 bases:

>100_bases
GTTGTTCGTGCTGCCCGCGGTTTATATGGTGGTAGGTCAGAAGCATCGTACGGAGGATGAGGTCAGCCATGGCTGACCTC
ATGTAGCGTGAGGCGGCAGC

Downstream 100 bases:

>100_bases
ACGCCGCCGGTCATTCTTTCCTTTGATTCAAGCCTTCGCTGCGGCTTATGATTTGCTCTGGATAATCCGTCGGAATACGA
CACCGGGAGGAGCGCACATG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MTRTEITIGEAAARSGVSAKMIRHYERIGLITPPLRGEANNYRFYDERLVHELRFIHRARDLGFAIVDIRALLSLWRDRN
RPSRDVKAIAVAHIAELEAKAAALHSMSAELRRLVESCHGSDRPDCPILEELANPGS

Sequences:

>Translated_137_residues
MTRTEITIGEAAARSGVSAKMIRHYERIGLITPPLRGEANNYRFYDERLVHELRFIHRARDLGFAIVDIRALLSLWRDRN
RPSRDVKAIAVAHIAELEAKAAALHSMSAELRRLVESCHGSDRPDCPILEELANPGS
>Mature_136_residues
TRTEITIGEAAARSGVSAKMIRHYERIGLITPPLRGEANNYRFYDERLVHELRFIHRARDLGFAIVDIRALLSLWRDRNR
PSRDVKAIAVAHIAELEAKAAALHSMSAELRRLVESCHGSDRPDCPILEELANPGS

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=128, Percent_Identity=39.0625, Blast_Score=98, Evalue=2e-22,
Organism=Escherichia coli, GI1789687, Length=133, Percent_Identity=36.0902255639098, Blast_Score=75, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15439; Mature: 15308

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTEITIGEAAARSGVSAKMIRHYERIGLITPPLRGEANNYRFYDERLVHELRFIHRAR
CCCCCEEHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DLGFAIVDIRALLSLWRDRNRPSRDVKAIAVAHIAELEAKAAALHSMSAELRRLVESCHG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDRPDCPILEELANPGS
CCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
TRTEITIGEAAARSGVSAKMIRHYERIGLITPPLRGEANNYRFYDERLVHELRFIHRAR
CCCCEEHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DLGFAIVDIRALLSLWRDRNRPSRDVKAIAVAHIAELEAKAAALHSMSAELRRLVESCHG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDRPDCPILEELANPGS
CCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]