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The map label for this gene is eno [H]

Identifier: 148243462

GI number: 148243462

Start: 2055324

End: 2056646

Strand: Direct

Name: eno [H]

Synonym: SynRCC307_2363

Alternate gene names: 148243462

Gene position: 2055324-2056646 (Clockwise)

Preceding gene: 148243448

Following gene: 148243469

Centisome position: 92.38

GC content: 63.57

Gene sequence:

>1323_bases
ATGAGCCCGCCAGATGAGACCGCTGTGTTCGACTCTCTCGACCTTGTGATCGACACCGTGGTGGCACGGGAAGTGTTGGA
CTCCCGCGGCACCCCAACCGTCGAAGCCGAGGTGTTGCTTGAGGGTGGCGCCAGCGGCCGGGCAATCGTGCCCAGCGGAG
CCAGCACCGGTGCCCACGAAGCCCATGAGCTGCGCGATGGCGACGCCATGCGTTATTTCGGCAAAGGGGTCAACCAAGCC
GTCAGCAATGTGGAAGAGCGGCTCGCTCCGGCCCTCTGCGGACTAAGCGCCCTCGATCAGGTGGCCGTCGATGGCGCCAT
GAACGAACTCGATGGCAGCGCGAATAAATCCAGCCTTGGTGCCAACGCGATCCTGGCGGTGAGCATGGCCGTGGCCCGCG
CAGCAGCCAACGGGGTTGGCCTGCCGCTGTACCGCTATCTGGGTGGCCCATCAGCAACGGTGCTGCCGGTGCCGCTGATG
AATGTGATCAATGGCGGCGAGCACGCCACCAACAACCTGGATTTCCAGGAATTCATGATCGTGCCCCATGGCGCCGGCAG
CTTCCGAGAAGCACTGCGCTGGGGCGCTGAGGTGTTCCACACCCTCAAGGGCCTGCTCAACGAGCAAGGCCTGTCAACAG
CCGTTGGTGATGAGGGCGGCTTTGCTCCCAACCTCGATGGCAACGATGCCGCCGGCGACTTGCTGGTGCGCGCGATCGAG
AAAGCCGGCTACAAGCCCGGTGAGCAAATTGCCTTGGCCCTCGATGTGGCCAGCACCGAGTTTTACAAAGACGGCCGCTA
CAGCTTTGGCGGCGGCAACTACAGCAGCGCGGAAATGGTGGATCAGCTGGCCCAGCTGGTGAGCCGCTACCCGATTGTGT
CGATCGAAGACGGCCTCGCCGAAGACGATTGGGATGGCTGGAAGCTGTTGACCGAGCGCTTGGGCAGCTCCGTGCAACTG
GTGGGCGACGACCTCTTCGTGACCAACAGCACCCGGCTGCAGCGCGGCATTGATCTGGGCGTGGCTAACTCGATCCTGAT
CAAGGTCAATCAGATCGGCTCGCTGAGCGAAACCCTGCAAGCCATCGACTTGGGAGGCCGCAACGGCTACACCAGCGTGA
TTAGCCACCGCAGCGGCGAAACCGAAGACACCACCATTGCCGATCTGGCAGTGGCCACCGGTGCTGGCCAAATCAAGACC
GGTTCCCTCAGCCGCTCTGAGCGGATCGCCAAGTACAACCAGCTGCTGCGCATCGAAGACGAGCTCGGTAGCCAAGCGGT
GTACGCCGGTACCCAAGGCCGCGGCCCCCGCGGCCGCCGCTGA

Upstream 100 bases:

>100_bases
AGGGAGCGCTCCAGATCGCCCACCCGAAGCATGGTGTGCAGCAAACGCATGGGGCGTTGATGGCTCTAGCTGAGCTCATT
GTGCAGGGCCCATCTGCATA

Downstream 100 bases:

>100_bases
TTAGCGCTGCTGGCCAGGAAGCTGCTCAAGCCGTTGATCACGCTGCAGCCTCAACTGCAGCTTGAGCCAACCCAACCCCA
CAGGAACCCCAGCCACCAAA

Product: phosphopyruvate hydratase

Products: NA

Alternate protein names: 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSPPDETAVFDSLDLVIDTVVAREVLDSRGTPTVEAEVLLEGGASGRAIVPSGASTGAHEAHELRDGDAMRYFGKGVNQA
VSNVEERLAPALCGLSALDQVAVDGAMNELDGSANKSSLGANAILAVSMAVARAAANGVGLPLYRYLGGPSATVLPVPLM
NVINGGEHATNNLDFQEFMIVPHGAGSFREALRWGAEVFHTLKGLLNEQGLSTAVGDEGGFAPNLDGNDAAGDLLVRAIE
KAGYKPGEQIALALDVASTEFYKDGRYSFGGGNYSSAEMVDQLAQLVSRYPIVSIEDGLAEDDWDGWKLLTERLGSSVQL
VGDDLFVTNSTRLQRGIDLGVANSILIKVNQIGSLSETLQAIDLGGRNGYTSVISHRSGETEDTTIADLAVATGAGQIKT
GSLSRSERIAKYNQLLRIEDELGSQAVYAGTQGRGPRGRR

Sequences:

>Translated_440_residues
MSPPDETAVFDSLDLVIDTVVAREVLDSRGTPTVEAEVLLEGGASGRAIVPSGASTGAHEAHELRDGDAMRYFGKGVNQA
VSNVEERLAPALCGLSALDQVAVDGAMNELDGSANKSSLGANAILAVSMAVARAAANGVGLPLYRYLGGPSATVLPVPLM
NVINGGEHATNNLDFQEFMIVPHGAGSFREALRWGAEVFHTLKGLLNEQGLSTAVGDEGGFAPNLDGNDAAGDLLVRAIE
KAGYKPGEQIALALDVASTEFYKDGRYSFGGGNYSSAEMVDQLAQLVSRYPIVSIEDGLAEDDWDGWKLLTERLGSSVQL
VGDDLFVTNSTRLQRGIDLGVANSILIKVNQIGSLSETLQAIDLGGRNGYTSVISHRSGETEDTTIADLAVATGAGQIKT
GSLSRSERIAKYNQLLRIEDELGSQAVYAGTQGRGPRGRR
>Mature_439_residues
SPPDETAVFDSLDLVIDTVVAREVLDSRGTPTVEAEVLLEGGASGRAIVPSGASTGAHEAHELRDGDAMRYFGKGVNQAV
SNVEERLAPALCGLSALDQVAVDGAMNELDGSANKSSLGANAILAVSMAVARAAANGVGLPLYRYLGGPSATVLPVPLMN
VINGGEHATNNLDFQEFMIVPHGAGSFREALRWGAEVFHTLKGLLNEQGLSTAVGDEGGFAPNLDGNDAAGDLLVRAIEK
AGYKPGEQIALALDVASTEFYKDGRYSFGGGNYSSAEMVDQLAQLVSRYPIVSIEDGLAEDDWDGWKLLTERLGSSVQLV
GDDLFVTNSTRLQRGIDLGVANSILIKVNQIGSLSETLQAIDLGGRNGYTSVISHRSGETEDTTIADLAVATGAGQIKTG
SLSRSERIAKYNQLLRIEDELGSQAVYAGTQGRGPRGRR

Specific function: Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis [H]

COG id: COG0148

COG function: function code G; Enolase

Gene ontology:

Cell location: Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the bacterial ce

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enolase family [H]

Homologues:

Organism=Homo sapiens, GI5803011, Length=436, Percent_Identity=52.5229357798165, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI4503571, Length=439, Percent_Identity=49.8861047835991, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI301897477, Length=439, Percent_Identity=50.1138952164009, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI301897469, Length=439, Percent_Identity=50.1138952164009, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI301897479, Length=437, Percent_Identity=45.0800915331808, Blast_Score=357, Evalue=9e-99,
Organism=Homo sapiens, GI169201331, Length=335, Percent_Identity=26.2686567164179, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI169201757, Length=335, Percent_Identity=26.2686567164179, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI239744207, Length=335, Percent_Identity=26.2686567164179, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI310129182, Length=125, Percent_Identity=32.8, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI310110045, Length=125, Percent_Identity=32.8, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI310120572, Length=125, Percent_Identity=32.8, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789141, Length=423, Percent_Identity=58.8652482269503, Blast_Score=479, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17536383, Length=438, Percent_Identity=53.8812785388128, Blast_Score=429, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI71995829, Length=438, Percent_Identity=53.8812785388128, Blast_Score=429, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI32563855, Length=304, Percent_Identity=43.421052631579, Blast_Score=201, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6323985, Length=433, Percent_Identity=49.6535796766744, Blast_Score=385, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321693, Length=433, Percent_Identity=51.0392609699769, Blast_Score=385, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6324974, Length=433, Percent_Identity=49.6535796766744, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6324969, Length=433, Percent_Identity=49.6535796766744, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6321968, Length=433, Percent_Identity=51.0392609699769, Blast_Score=366, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24580918, Length=442, Percent_Identity=49.3212669683258, Blast_Score=387, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24580916, Length=442, Percent_Identity=49.3212669683258, Blast_Score=387, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24580920, Length=442, Percent_Identity=49.3212669683258, Blast_Score=387, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24580914, Length=442, Percent_Identity=49.3212669683258, Blast_Score=387, Evalue=1e-108,
Organism=Drosophila melanogaster, GI281360527, Length=438, Percent_Identity=49.3150684931507, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI17137654, Length=438, Percent_Identity=49.3150684931507, Blast_Score=383, Evalue=1e-106,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000941
- InterPro:   IPR020810
- InterPro:   IPR020809
- InterPro:   IPR020811 [H]

Pfam domain/function: PF00113 Enolase_C; PF03952 Enolase_N [H]

EC number: =4.2.1.11 [H]

Molecular weight: Translated: 46176; Mature: 46045

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00164 ENOLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPDETAVFDSLDLVIDTVVAREVLDSRGTPTVEAEVLLEGGASGRAIVPSGASTGAHE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEECCCCCCCCHH
AHELRDGDAMRYFGKGVNQAVSNVEERLAPALCGLSALDQVAVDGAMNELDGSANKSSLG
HHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ANAILAVSMAVARAAANGVGLPLYRYLGGPSATVLPVPLMNVINGGEHATNNLDFQEFMI
CHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEECHHHHHHHCCCCCCCCCCCHHHEEE
VPHGAGSFREALRWGAEVFHTLKGLLNEQGLSTAVGDEGGFAPNLDGNDAAGDLLVRAIE
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KAGYKPGEQIALALDVASTEFYKDGRYSFGGGNYSSAEMVDQLAQLVSRYPIVSIEDGLA
HCCCCCCHHEEEEEEEHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCC
EDDWDGWKLLTERLGSSVQLVGDDLFVTNSTRLQRGIDLGVANSILIKVNQIGSLSETLQ
CCCCCHHHHHHHHCCCCEEEECCEEEEECCHHHHHCCCCCCCCEEEEEEECCCCHHHHHH
AIDLGGRNGYTSVISHRSGETEDTTIADLAVATGAGQIKTGSLSRSERIAKYNQLLRIED
HHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHEEEHH
ELGSQAVYAGTQGRGPRGRR
HHCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
SPPDETAVFDSLDLVIDTVVAREVLDSRGTPTVEAEVLLEGGASGRAIVPSGASTGAHE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEECCCCCCCCHH
AHELRDGDAMRYFGKGVNQAVSNVEERLAPALCGLSALDQVAVDGAMNELDGSANKSSLG
HHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ANAILAVSMAVARAAANGVGLPLYRYLGGPSATVLPVPLMNVINGGEHATNNLDFQEFMI
CHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEECHHHHHHHCCCCCCCCCCCHHHEEE
VPHGAGSFREALRWGAEVFHTLKGLLNEQGLSTAVGDEGGFAPNLDGNDAAGDLLVRAIE
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KAGYKPGEQIALALDVASTEFYKDGRYSFGGGNYSSAEMVDQLAQLVSRYPIVSIEDGLA
HCCCCCCHHEEEEEEEHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCC
EDDWDGWKLLTERLGSSVQLVGDDLFVTNSTRLQRGIDLGVANSILIKVNQIGSLSETLQ
CCCCCHHHHHHHHCCCCEEEECCEEEEECCHHHHHCCCCCCCCEEEEEEECCCCHHHHHH
AIDLGGRNGYTSVISHRSGETEDTTIADLAVATGAGQIKTGSLSRSERIAKYNQLLRIED
HHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHEEEHH
ELGSQAVYAGTQGRGPRGRR
HHCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA