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The map label for this gene is ppnK [H]

Identifier: 148243380

GI number: 148243380

Start: 1982477

End: 1983424

Strand: Direct

Name: ppnK [H]

Synonym: SynRCC307_2281

Alternate gene names: 148243380

Gene position: 1982477-1983424 (Clockwise)

Preceding gene: 148243379

Following gene: 148243381

Centisome position: 89.1

GC content: 63.61

Gene sequence:

>948_bases
ATGGACTTGCGGCGGGTATGGGTGATTGTCCGCAGCGGTAGCCAAACCGCCCAGCGGATTGCCAGCCGCTGCTGCGAGCA
GCTGGAAGCCCGCGGATGCGCGGTGATCTGCGCCACCAGTGGGCTCACGACCAACCCCTATCCAGGCCTATTGGCTGATG
ACCGGCTTCCCGATCTGGTGCTGGTGCTGGGGGGCGATGGCACAGTTCTCAGTGCCGCCCGTTATTTGGCGGCACTGGAT
GTGCCGATCTTGAGCTTCAACGTGGGGGGCCACCTGGGCTTTCTGACCCACGAATTCGTGCTGCTGGAATCGCTGTTGAG
TGGGGATGGTTCGGGGCTATGGCAGCGCCTGGAAGACCACCATTACGCCCTCACCCAACGGCTGATGCTGCAAGCCAGCA
TTGACCGCGGCGATGGAATCCCCGATAGCGGTGATCACCACGACAAGCAGGGCCAGCTCTGCCATTTGGCGCTGAACGAC
TTCTATCTGCGGCCCGCCCAGGAAGAAGCCACACCCACCTGCCGCTTGGAGGTGGAGATCGATGGCGAAGTGGTGGGGCA
ATACCAAGGCGATGGCTTGATCGTGGCCTCACCCACGGGCTCCACCGGCTACGCCATGGCAGCGGGTGGGCCAATCCTGC
ACCCAGCCATCGATGCCATCGTTGTCAATCCGATCTGCCCGATGAGCCTCTCCAGCCGGCCGGTGGTGGTGCCGCCCAGG
TCGATCCTGGCGATCTGGCCGGTGGGCGACAGCGCCCGGCGGGTGAAACTGTGGAAAGACGGAGCCCTGGCCGGCGAACT
GGAGCCAGGTGATCGCTGCATCGTGCAGCAGGCCGATCACCATGCCCGGCTGGTGGCCTTGGAACAACAGCCCTCCTACT
TCAGCAATTTGAGCCGCAAGCTGCATTGGGCCGGCAGCCTCACCGATGCCATGCCATCGCAGAACTAA

Upstream 100 bases:

>100_bases
GAAGCAGCTGTTGGCTTGGCGATCTTGTTGTCGCTCTACCGCAACCGCGACACAGTGGATATGGAGCGTTTCAACCTGCT
GCGCTGGTAGCCAGTAACCC

Downstream 100 bases:

>100_bases
GCCATGGCCCTTGAGATCGAACGGCGCTTTTTCGTGGTTTCAGAGGCCTGGCAGGAGCTGAGCGTCAAGCACGAACAACT
CGACCAGGGCTACCTCAGCG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 2 [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MDLRRVWVIVRSGSQTAQRIASRCCEQLEARGCAVICATSGLTTNPYPGLLADDRLPDLVLVLGGDGTVLSAARYLAALD
VPILSFNVGGHLGFLTHEFVLLESLLSGDGSGLWQRLEDHHYALTQRLMLQASIDRGDGIPDSGDHHDKQGQLCHLALND
FYLRPAQEEATPTCRLEVEIDGEVVGQYQGDGLIVASPTGSTGYAMAAGGPILHPAIDAIVVNPICPMSLSSRPVVVPPR
SILAIWPVGDSARRVKLWKDGALAGELEPGDRCIVQQADHHARLVALEQQPSYFSNLSRKLHWAGSLTDAMPSQN

Sequences:

>Translated_315_residues
MDLRRVWVIVRSGSQTAQRIASRCCEQLEARGCAVICATSGLTTNPYPGLLADDRLPDLVLVLGGDGTVLSAARYLAALD
VPILSFNVGGHLGFLTHEFVLLESLLSGDGSGLWQRLEDHHYALTQRLMLQASIDRGDGIPDSGDHHDKQGQLCHLALND
FYLRPAQEEATPTCRLEVEIDGEVVGQYQGDGLIVASPTGSTGYAMAAGGPILHPAIDAIVVNPICPMSLSSRPVVVPPR
SILAIWPVGDSARRVKLWKDGALAGELEPGDRCIVQQADHHARLVALEQQPSYFSNLSRKLHWAGSLTDAMPSQN
>Mature_315_residues
MDLRRVWVIVRSGSQTAQRIASRCCEQLEARGCAVICATSGLTTNPYPGLLADDRLPDLVLVLGGDGTVLSAARYLAALD
VPILSFNVGGHLGFLTHEFVLLESLLSGDGSGLWQRLEDHHYALTQRLMLQASIDRGDGIPDSGDHHDKQGQLCHLALND
FYLRPAQEEATPTCRLEVEIDGEVVGQYQGDGLIVASPTGSTGYAMAAGGPILHPAIDAIVVNPICPMSLSSRPVVVPPR
SILAIWPVGDSARRVKLWKDGALAGELEPGDRCIVQQADHHARLVALEQQPSYFSNLSRKLHWAGSLTDAMPSQN

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=261, Percent_Identity=29.8850574712644, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788968, Length=269, Percent_Identity=33.8289962825279, Blast_Score=125, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6322509, Length=311, Percent_Identity=30.8681672025724, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6320794, Length=258, Percent_Identity=30.2325581395349, Blast_Score=102, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6325068, Length=225, Percent_Identity=31.5555555555556, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28573830, Length=257, Percent_Identity=34.2412451361868, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573828, Length=257, Percent_Identity=34.2412451361868, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161077047, Length=257, Percent_Identity=34.2412451361868, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573832, Length=257, Percent_Identity=34.2412451361868, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573826, Length=257, Percent_Identity=34.2412451361868, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20129957, Length=281, Percent_Identity=32.3843416370107, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24653422, Length=281, Percent_Identity=32.3843416370107, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363323, Length=281, Percent_Identity=32.3843416370107, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363321, Length=281, Percent_Identity=32.3843416370107, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24653424, Length=281, Percent_Identity=32.3843416370107, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33921; Mature: 33921

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRRVWVIVRSGSQTAQRIASRCCEQLEARGCAVICATSGLTTNPYPGLLADDRLPDLV
CCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCEE
LVLGGDGTVLSAARYLAALDVPILSFNVGGHLGFLTHEFVLLESLLSGDGSGLWQRLEDH
EEECCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HYALTQRLMLQASIDRGDGIPDSGDHHDKQGQLCHLALNDFYLRPAQEEATPTCRLEVEI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEECCCCCCCCCEEEEEEEE
DGEVVGQYQGDGLIVASPTGSTGYAMAAGGPILHPAIDAIVVNPICPMSLSSRPVVVPPR
CCEEEEEECCCEEEEECCCCCCCEEEECCCCCHHHHHHEEEECCCCCCCCCCCCEEECCC
SILAIWPVGDSARRVKLWKDGALAGELEPGDRCIVQQADHHARLVALEQQPSYFSNLSRK
CEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHE
LHWAGSLTDAMPSQN
EEECCCCCCCCCCCC
>Mature Secondary Structure
MDLRRVWVIVRSGSQTAQRIASRCCEQLEARGCAVICATSGLTTNPYPGLLADDRLPDLV
CCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCEE
LVLGGDGTVLSAARYLAALDVPILSFNVGGHLGFLTHEFVLLESLLSGDGSGLWQRLEDH
EEECCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HYALTQRLMLQASIDRGDGIPDSGDHHDKQGQLCHLALNDFYLRPAQEEATPTCRLEVEI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEECCCCCCCCCEEEEEEEE
DGEVVGQYQGDGLIVASPTGSTGYAMAAGGPILHPAIDAIVVNPICPMSLSSRPVVVPPR
CCEEEEEECCCEEEEECCCCCCCEEEECCCCCHHHHHHEEEECCCCCCCCCCCCEEECCC
SILAIWPVGDSARRVKLWKDGALAGELEPGDRCIVQQADHHARLVALEQQPSYFSNLSRK
CEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHE
LHWAGSLTDAMPSQN
EEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]