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The map label for this gene is purE [H]

Identifier: 148243364

GI number: 148243364

Start: 1969979

End: 1970497

Strand: Direct

Name: purE [H]

Synonym: SynRCC307_2265

Alternate gene names: 148243364

Gene position: 1969979-1970497 (Clockwise)

Preceding gene: 148243361

Following gene: 148243365

Centisome position: 88.54

GC content: 65.7

Gene sequence:

>519_bases
ATGACAGCCCCGGCACGGGTGGGAGTGGTGATGGGAAGCGATTCCGACCTGCCCTGCATGCACAAGGCTGTAGAGATGCT
GGAGACCTTCGGCGTAGCCCATGAAGTGCGGGTGCTCTCCGCCCACCGCACGCCGCTCGCCATGACCGAGTACGCCCAAC
AAGCCGAAGCGCGGGGCCTGCAGGTGGTGATTGCGGGCGCTGGCGGCGCCGCCCACCTGCCCGGGATGGTGGCGGCCCTC
ACCACCCTGCCGGTGATTGGCGTGCCAGTGAGCAGCAAAGCGCTCTCCGGGGTGGATTCGCTCTACTCGATCGTGCAGAT
GCCCGCCGGCATCCCCGTGGCCACCGTGGCCATCGGCAATGCTGCCAATGCAGGGCTCTTGGCCCTGCAAATCCTGGCCA
TTAGTGATCCAGCCTTGCGCGAGCAACTACACAACTACCGCCGAGGCCTGGCCGAGATGGTGACCGCCAAAGATGCCCGG
CTTCAGGAGTTGGGCAGCAGCAACTATCTGGCGCAGTGA

Upstream 100 bases:

>100_bases
CGCCAGCGCCGCTCCGGCACACCGATCGGTTCGGGCAAGCGCAGATTCGTGTGCCACTGCATGCCGATGTGGTGAAAATG
CCCGCAGTTGCAGTCTGCCG

Downstream 100 bases:

>100_bases
TGAACCTGCCGCGCTGGTTACGCCTGAGCCTGATCCTGCCCTTACTGGGGTTGAACCTGTTTGTGCTGCGCCAGGCGCTG
CTCCGCCTAGCGCCTTTTCC

Product: phosphoribosylaminoimidazole carboxylase catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MTAPARVGVVMGSDSDLPCMHKAVEMLETFGVAHEVRVLSAHRTPLAMTEYAQQAEARGLQVVIAGAGGAAHLPGMVAAL
TTLPVIGVPVSSKALSGVDSLYSIVQMPAGIPVATVAIGNAANAGLLALQILAISDPALREQLHNYRRGLAEMVTAKDAR
LQELGSSNYLAQ

Sequences:

>Translated_172_residues
MTAPARVGVVMGSDSDLPCMHKAVEMLETFGVAHEVRVLSAHRTPLAMTEYAQQAEARGLQVVIAGAGGAAHLPGMVAAL
TTLPVIGVPVSSKALSGVDSLYSIVQMPAGIPVATVAIGNAANAGLLALQILAISDPALREQLHNYRRGLAEMVTAKDAR
LQELGSSNYLAQ
>Mature_171_residues
TAPARVGVVMGSDSDLPCMHKAVEMLETFGVAHEVRVLSAHRTPLAMTEYAQQAEARGLQVVIAGAGGAAHLPGMVAALT
TLPVIGVPVSSKALSGVDSLYSIVQMPAGIPVATVAIGNAANAGLLALQILAISDPALREQLHNYRRGLAEMVTAKDARL
QELGSSNYLAQ

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=153, Percent_Identity=58.1699346405229, Blast_Score=149, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324702, Length=164, Percent_Identity=54.8780487804878, Blast_Score=177, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17778; Mature: 17647

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPARVGVVMGSDSDLPCMHKAVEMLETFGVAHEVRVLSAHRTPLAMTEYAQQAEARGL
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCE
QVVIAGAGGAAHLPGMVAALTTLPVIGVPVSSKALSGVDSLYSIVQMPAGIPVATVAIGN
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECC
AANAGLLALQILAISDPALREQLHNYRRGLAEMVTAKDARLQELGSSNYLAQ
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TAPARVGVVMGSDSDLPCMHKAVEMLETFGVAHEVRVLSAHRTPLAMTEYAQQAEARGL
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCE
QVVIAGAGGAAHLPGMVAALTTLPVIGVPVSSKALSGVDSLYSIVQMPAGIPVATVAIGN
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECC
AANAGLLALQILAISDPALREQLHNYRRGLAEMVTAKDARLQELGSSNYLAQ
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]