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The map label for this gene is hisC [H]

Identifier: 148243341

GI number: 148243341

Start: 1951538

End: 1952629

Strand: Direct

Name: hisC [H]

Synonym: SynRCC307_2242

Alternate gene names: 148243341

Gene position: 1951538-1952629 (Clockwise)

Preceding gene: 148243340

Following gene: 148243349

Centisome position: 87.71

GC content: 63.28

Gene sequence:

>1092_bases
ATGCCGGATCCACGCCCACAGTTCCCCCCGGCCCGCAGCGAGGTGGAGCAACTGCAGAGCTACAGCGCCCCACTGGAGGG
ACGCCGGGGCATGCTGCGCCTGGACTTCAACGAAAACAGCGTCGGCCCGAGCCCCAAGGTGGTGGAGGCGATCCGCAGCA
TCCCAGCCGAGCACTACGCGATCTACCCCGAATACGACGGCCTACGCGAGGCCTTCAGTCAGTCCCTCGGCGGACTGCCG
TGCGACCAGATCGGGCTGTTCAACGGCGTTGACGCGGCCCTGCATGCCATCTGCCAGGCCTATGGCAACCCCGGCGATGT
GATGCTCACCACCAGCCCCACCTTTGGCTACTACCAACCTTGTGCCCGCATGCAGGGGATGGTGGTGAACGCCATTCCCT
ATGAGGGAGACGACTACCGCTTCCCGCTGCAGGACATGCAGCGGGCCTTAGCGCAACTCAACCCGCGACTGCTGCTGCTC
TGCAACCCCAACAACCCCACAGGCACCCGGCTAGGGGCTGAGGCGATCTGCCAGCTGGCAGCCGCCGCACCCAGCACGCT
GGTGGTGGTGGATGAGCTCTATGAGGCCTTCACCGGAGACAGCGTTCTGCCGCAAGCCGATTTCAGCCAAACGCCCAACT
TGGTGGTGCTGCGCTCGCTCTCCAAAACGGCTGGCATCGCTGGGCTGCGCCTCGGCATTGCCCTGGGCTCAGCTGCAGTG
GTGGATCGCATCAGCCGGGTCACCGGCCCCTACGACATCAACAGCTTTGCCGTGATCGCAGGCATGGCGGCGCTGCATGA
CCAGGCGTATGTCGATGACTACGTCCAAGAGGTTCTCAAAGCCAAGGCATGGCTTGTGAACAAGCTCATCAAGCACCAAG
TCCGCCATCACAGCGCCGGCGGCAACTACCTACTGATTTGGCCAAGCCAAGGGGCCGCCAGCTGTGAGGTTGCGCTGCGG
CAGGAAGAAATCCTGGTGCGTTCGATGGCGGGCAAACCCCTGATCGATGGGTCCCTACGGGTGAGCATCGGAACCACCAA
ACAAATGAAGCGGTTCTGGAAAGCTTTCAGCGCGCAACAGGGGCTGAGCTGA

Upstream 100 bases:

>100_bases
AACCGATGCGCAGCTCGAGGCTGGCCCTCTGCCGTTTAGCGGCTGACACCCTCAAGCTGGGGCTAAGCCTGCTGGGCATT
CCCAGCCTGGAGCGGATGTG

Downstream 100 bases:

>100_bases
ACGCGCATCGGTGCCGATCAGGCCCACACAGGCCAAGGTCAGCACCCCTTGCAGGGCAAGGCAGAGGCCGATTGCTCGAC
GTTGATGCCAAATCGTTCCC

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MPDPRPQFPPARSEVEQLQSYSAPLEGRRGMLRLDFNENSVGPSPKVVEAIRSIPAEHYAIYPEYDGLREAFSQSLGGLP
CDQIGLFNGVDAALHAICQAYGNPGDVMLTTSPTFGYYQPCARMQGMVVNAIPYEGDDYRFPLQDMQRALAQLNPRLLLL
CNPNNPTGTRLGAEAICQLAAAAPSTLVVVDELYEAFTGDSVLPQADFSQTPNLVVLRSLSKTAGIAGLRLGIALGSAAV
VDRISRVTGPYDINSFAVIAGMAALHDQAYVDDYVQEVLKAKAWLVNKLIKHQVRHHSAGGNYLLIWPSQGAASCEVALR
QEEILVRSMAGKPLIDGSLRVSIGTTKQMKRFWKAFSAQQGLS

Sequences:

>Translated_363_residues
MPDPRPQFPPARSEVEQLQSYSAPLEGRRGMLRLDFNENSVGPSPKVVEAIRSIPAEHYAIYPEYDGLREAFSQSLGGLP
CDQIGLFNGVDAALHAICQAYGNPGDVMLTTSPTFGYYQPCARMQGMVVNAIPYEGDDYRFPLQDMQRALAQLNPRLLLL
CNPNNPTGTRLGAEAICQLAAAAPSTLVVVDELYEAFTGDSVLPQADFSQTPNLVVLRSLSKTAGIAGLRLGIALGSAAV
VDRISRVTGPYDINSFAVIAGMAALHDQAYVDDYVQEVLKAKAWLVNKLIKHQVRHHSAGGNYLLIWPSQGAASCEVALR
QEEILVRSMAGKPLIDGSLRVSIGTTKQMKRFWKAFSAQQGLS
>Mature_362_residues
PDPRPQFPPARSEVEQLQSYSAPLEGRRGMLRLDFNENSVGPSPKVVEAIRSIPAEHYAIYPEYDGLREAFSQSLGGLPC
DQIGLFNGVDAALHAICQAYGNPGDVMLTTSPTFGYYQPCARMQGMVVNAIPYEGDDYRFPLQDMQRALAQLNPRLLLLC
NPNNPTGTRLGAEAICQLAAAAPSTLVVVDELYEAFTGDSVLPQADFSQTPNLVVLRSLSKTAGIAGLRLGIALGSAAVV
DRISRVTGPYDINSFAVIAGMAALHDQAYVDDYVQEVLKAKAWLVNKLIKHQVRHHSAGGNYLLIWPSQGAASCEVALRQ
EEILVRSMAGKPLIDGSLRVSIGTTKQMKRFWKAFSAQQGLS

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=365, Percent_Identity=27.9452054794521, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788627, Length=202, Percent_Identity=27.2277227722772, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322075, Length=376, Percent_Identity=26.5957446808511, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39406; Mature: 39274

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPRPQFPPARSEVEQLQSYSAPLEGRRGMLRLDFNENSVGPSPKVVEAIRSIPAEHYA
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHEE
IYPEYDGLREAFSQSLGGLPCDQIGLFNGVDAALHAICQAYGNPGDVMLTTSPTFGYYQP
ECCCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
CARMQGMVVNAIPYEGDDYRFPLQDMQRALAQLNPRLLLLCNPNNPTGTRLGAEAICQLA
HHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
AAAPSTLVVVDELYEAFTGDSVLPQADFSQTPNLVVLRSLSKTAGIAGLRLGIALGSAAV
HCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHH
VDRISRVTGPYDINSFAVIAGMAALHDQAYVDDYVQEVLKAKAWLVNKLIKHQVRHHSAG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GNYLLIWPSQGAASCEVALRQEEILVRSMAGKPLIDGSLRVSIGTTKQMKRFWKAFSAQQ
CCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCHHHHHHHHHHHHHHC
GLS
CCC
>Mature Secondary Structure 
PDPRPQFPPARSEVEQLQSYSAPLEGRRGMLRLDFNENSVGPSPKVVEAIRSIPAEHYA
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHEE
IYPEYDGLREAFSQSLGGLPCDQIGLFNGVDAALHAICQAYGNPGDVMLTTSPTFGYYQP
ECCCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
CARMQGMVVNAIPYEGDDYRFPLQDMQRALAQLNPRLLLLCNPNNPTGTRLGAEAICQLA
HHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
AAAPSTLVVVDELYEAFTGDSVLPQADFSQTPNLVVLRSLSKTAGIAGLRLGIALGSAAV
HCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHH
VDRISRVTGPYDINSFAVIAGMAALHDQAYVDDYVQEVLKAKAWLVNKLIKHQVRHHSAG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GNYLLIWPSQGAASCEVALRQEEILVRSMAGKPLIDGSLRVSIGTTKQMKRFWKAFSAQQ
CCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCHHHHHHHHHHHHHHC
GLS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9043133 [H]