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The map label for this gene is txlA [H]

Identifier: 148243323

GI number: 148243323

Start: 1930287

End: 1930850

Strand: Direct

Name: txlA [H]

Synonym: SynRCC307_2224

Alternate gene names: 148243323

Gene position: 1930287-1930850 (Clockwise)

Preceding gene: 148243320

Following gene: 148243325

Centisome position: 86.76

GC content: 63.83

Gene sequence:

>564_bases
ATGAGCAGCACCCCTGCCGGCCCCGAATTCCCTGGGAAGAGGCTCCCTCAGCTGGTGCTACTGCTGCTGGCCATCGTTGT
GGTGGCTGTGGTTTGGCTGGAGGGCGGTCGCTCCGAGGGCGACCTGCTCGATCAGATGGCCCGGCGCTCACTGCCTTTGG
AGCAAGCCCTGAGCAACGGCAAGCCCTCGGTGGTCGAGTTCTATGCGGACTGGTGTGAGTCGTGCCGAACCATGGCTCCC
GGCATGGAGCAAATGGTCAAAGACCATCCCCAGGTCGATCTGGTTTTGCTGAATGTCGACAACCCCAGCTGGCAGCCCCA
AGTGCAGCGCTGGAACGTCAATGGCATTCCCCATCTGCAGCTCTTTGATGCCAATGGCGAGAGCCGTGGGCAGTCGATTG
GCTTACGCCAACCGCAAGAGCTGAGCGCCATCGCCGTCGCCCTGGAAACCGGCGAACCCCTGCCCACCCTGGCGGGCATC
GGCGCCATCAGCAGCTTGGATCCCTCCGAGGAGCCCAGTCGGCGTGACATCAGCAGCAACGTGGGCCCGCGCAGCCACGG
CTAA

Upstream 100 bases:

>100_bases
ATGCACGGCTTCCCGAGGGAATTGCAGCGTCAAGCGACGCTTCACGGCACACAGGGGAGCATCGCTGCCAGCATGGCAGC
GCCCCAACAGCGCCGCAGCC

Downstream 100 bases:

>100_bases
GCCTCAGCAGCGAGATCTTGCAGCAGCTGGGAGAGCAAGCGATCGGCATCACGAACCGCCAACCGCTCCATGCCTTGGCG
GAGCAAGCGCAGCGGATCTG

Product: thioredoxin

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSSTPAGPEFPGKRLPQLVLLLLAIVVVAVVWLEGGRSEGDLLDQMARRSLPLEQALSNGKPSVVEFYADWCESCRTMAP
GMEQMVKDHPQVDLVLLNVDNPSWQPQVQRWNVNGIPHLQLFDANGESRGQSIGLRQPQELSAIAVALETGEPLPTLAGI
GAISSLDPSEEPSRRDISSNVGPRSHG

Sequences:

>Translated_187_residues
MSSTPAGPEFPGKRLPQLVLLLLAIVVVAVVWLEGGRSEGDLLDQMARRSLPLEQALSNGKPSVVEFYADWCESCRTMAP
GMEQMVKDHPQVDLVLLNVDNPSWQPQVQRWNVNGIPHLQLFDANGESRGQSIGLRQPQELSAIAVALETGEPLPTLAGI
GAISSLDPSEEPSRRDISSNVGPRSHG
>Mature_186_residues
SSTPAGPEFPGKRLPQLVLLLLAIVVVAVVWLEGGRSEGDLLDQMARRSLPLEQALSNGKPSVVEFYADWCESCRTMAPG
MEQMVKDHPQVDLVLLNVDNPSWQPQVQRWNVNGIPHLQLFDANGESRGQSIGLRQPQELSAIAVALETGEPLPTLAGIG
AISSLDPSEEPSRRDISSNVGPRSHG

Specific function: Required for disulfide bond formation in some proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 20235; Mature: 20104

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTPAGPEFPGKRLPQLVLLLLAIVVVAVVWLEGGRSEGDLLDQMARRSLPLEQALSNG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCC
KPSVVEFYADWCESCRTMAPGMEQMVKDHPQVDLVLLNVDNPSWQPQVQRWNVNGIPHLQ
CCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCCEEE
LFDANGESRGQSIGLRQPQELSAIAVALETGEPLPTLAGIGAISSLDPSEEPSRRDISSN
EECCCCCCCCCCCCCCCCHHHHHHHEECCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHC
VGPRSHG
CCCCCCC
>Mature Secondary Structure 
SSTPAGPEFPGKRLPQLVLLLLAIVVVAVVWLEGGRSEGDLLDQMARRSLPLEQALSNG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCC
KPSVVEFYADWCESCRTMAPGMEQMVKDHPQVDLVLLNVDNPSWQPQVQRWNVNGIPHLQ
CCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCCCCEEE
LFDANGESRGQSIGLRQPQELSAIAVALETGEPLPTLAGIGAISSLDPSEEPSRRDISSN
EECCCCCCCCCCCCCCCCHHHHHHHEECCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHC
VGPRSHG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]