Click here to switch to the map view.

The map label for this gene is ffh [H]

Identifier: 148242807

GI number: 148242807

Start: 1492942

End: 1494423

Strand: Direct

Name: ffh [H]

Synonym: SynRCC307_1708

Alternate gene names: 148242807

Gene position: 1492942-1494423 (Clockwise)

Preceding gene: 148242806

Following gene: 148242808

Centisome position: 67.1

GC content: 64.37

Gene sequence:

>1482_bases
TTGGCGGCGCTGATGTTTGAAGAGCTCTCCCAACGGTTTGAGGATGCCGTCCGCGGCCTCAAGGGCGAAGCCTCGATCAG
CGAGGGCAACGTAGACAGCGCCCTAAAAGACGTACGCCGCGCCCTGCTGGATGCCGACGTCAGCCTGCCGGTGGTCAAAA
GCTTCATCGCTGAGGTGCGCGAGAAAGCCCTCGGCGCTGACGTGGTGCGTGGCGTCAGCCCCGATCAGCAGTTCATCAAG
CTTGTCCACGAGGAGCTTGTTGAGGTGATGGGCGGGGCCAATGCGCCCCTGGCCAAGGCCGAACAATCCCCCACCGTGGT
GCTGATGGCCGGCCTGCAGGGCGCCGGTAAAACCACCGCCACCGCCAAGCTCGGACTGCACCTCAAAGAGCAGGGGCGTA
GAGCGCTGCTGGTGGCCGCCGACACCTACCGGCCAGCAGCCATCGATCAGCTGCAAACGCTCGGCCAACAGATTGATGTG
GAGGTGTTCAGCCTTGGCGCTGATGCCAAGCCCGAAGCTATTGCCGAAGCGGGCCTAGCCAAGGGCCGCGAAGAAGGCTT
CGACACGGTGATCGTCGACACCGCCGGCCGCCTGCAGATCGACACCTCGATGATGGAGGAGATGGTGCGGATCCGCAGCG
CCGTGGCACCCGATGAGGTGCTGCTGGTGGTGGATTCGATGATTGGCCAGGAGGCCGCTGACCTCACCCGCTCGTTCCAT
GAGCAGGTGGGCATCACCGGGGCCGTGCTCACCAAGATGGACGGCGACTCCAGGGGTGGCGCGGCTCTTTCGATCCGCAA
GGTCAGCGGCGCACCGATCAAATTCATCGGCACCGGCGAGAAGGTGGAGGCGCTGCAGCCCTTCCACCCCGAGCGGATGG
CCAGCCGCATTCTCGGCATGGGTGATGTGCTCACCCTGGTGGAGAAGGCCCAGAAGGAAGTTGAGATCGCCGATGTCGAG
AAGATGCAGCGCAAGCTGCAGGAAGCCAGCTTCGACTTCTCCGATTTCGTCAAGCAGATGCGCCTGATCAAGCGCATGGG
CTCGCTGGGGGGCCTGATGAAAATGATCCCGGGGATGAACAAGATCGACGACGGGATGCTCAAGCAGGGCGAAGCCCAGC
TCAAGCGCATCGAAGCGATGATCGGCTCGATGACCGTTCAAGAGCGGGAAAACCCCGACCTGCTCGCCAGCCAGCCCTCC
CGGCGGCGCCGCATCGCCAAAGGCAGCGGCCACCAACCAGCTGAGGTGGACAAGATGCTGGCCGACTTCCAGAAGATGCG
GGGCTTCATGCAGCAGATGAGCCGCGGCGGCGGCATGCCGGGAATGCCTGGGATGCCCGGCATGGGCGGCATGCCTGGAA
TGGGCGGTATGCCGGGGATGCCTGGCATGGGCGGAATGCCCGGCATGGGCGGCGGCGGTGGTGGGCGCCCCGGCAAAAAG
ATGAAGCCCGCCAAGAAGCGCAAGGGCTTCGGAGAGCTGTAA

Upstream 100 bases:

>100_bases
ACGTGTACGAGAAAAAAGGCGACAGCTGGCAGCTGACCGACTTCCGCCCCAGCATCTAGCGCTGAGCTGATTCCTACGAT
GGAGGGCTTGTAGCCCTGGA

Downstream 100 bases:

>100_bases
GGGTCAAGCGGTATGGTGGTGGATTCATGTCCACGACCGTTCGAGATCCCGATGATCAAGCTCCGCCTGAAGCGCTTCGG
TAAGAAGCGGGAAACGAGCT

Product: Signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MAALMFEELSQRFEDAVRGLKGEASISEGNVDSALKDVRRALLDADVSLPVVKSFIAEVREKALGADVVRGVSPDQQFIK
LVHEELVEVMGGANAPLAKAEQSPTVVLMAGLQGAGKTTATAKLGLHLKEQGRRALLVAADTYRPAAIDQLQTLGQQIDV
EVFSLGADAKPEAIAEAGLAKGREEGFDTVIVDTAGRLQIDTSMMEEMVRIRSAVAPDEVLLVVDSMIGQEAADLTRSFH
EQVGITGAVLTKMDGDSRGGAALSIRKVSGAPIKFIGTGEKVEALQPFHPERMASRILGMGDVLTLVEKAQKEVEIADVE
KMQRKLQEASFDFSDFVKQMRLIKRMGSLGGLMKMIPGMNKIDDGMLKQGEAQLKRIEAMIGSMTVQERENPDLLASQPS
RRRRIAKGSGHQPAEVDKMLADFQKMRGFMQQMSRGGGMPGMPGMPGMGGMPGMGGMPGMPGMGGMPGMGGGGGGRPGKK
MKPAKKRKGFGEL

Sequences:

>Translated_493_residues
MAALMFEELSQRFEDAVRGLKGEASISEGNVDSALKDVRRALLDADVSLPVVKSFIAEVREKALGADVVRGVSPDQQFIK
LVHEELVEVMGGANAPLAKAEQSPTVVLMAGLQGAGKTTATAKLGLHLKEQGRRALLVAADTYRPAAIDQLQTLGQQIDV
EVFSLGADAKPEAIAEAGLAKGREEGFDTVIVDTAGRLQIDTSMMEEMVRIRSAVAPDEVLLVVDSMIGQEAADLTRSFH
EQVGITGAVLTKMDGDSRGGAALSIRKVSGAPIKFIGTGEKVEALQPFHPERMASRILGMGDVLTLVEKAQKEVEIADVE
KMQRKLQEASFDFSDFVKQMRLIKRMGSLGGLMKMIPGMNKIDDGMLKQGEAQLKRIEAMIGSMTVQERENPDLLASQPS
RRRRIAKGSGHQPAEVDKMLADFQKMRGFMQQMSRGGGMPGMPGMPGMGGMPGMGGMPGMPGMGGMPGMGGGGGGRPGKK
MKPAKKRKGFGEL
>Mature_492_residues
AALMFEELSQRFEDAVRGLKGEASISEGNVDSALKDVRRALLDADVSLPVVKSFIAEVREKALGADVVRGVSPDQQFIKL
VHEELVEVMGGANAPLAKAEQSPTVVLMAGLQGAGKTTATAKLGLHLKEQGRRALLVAADTYRPAAIDQLQTLGQQIDVE
VFSLGADAKPEAIAEAGLAKGREEGFDTVIVDTAGRLQIDTSMMEEMVRIRSAVAPDEVLLVVDSMIGQEAADLTRSFHE
QVGITGAVLTKMDGDSRGGAALSIRKVSGAPIKFIGTGEKVEALQPFHPERMASRILGMGDVLTLVEKAQKEVEIADVEK
MQRKLQEASFDFSDFVKQMRLIKRMGSLGGLMKMIPGMNKIDDGMLKQGEAQLKRIEAMIGSMTVQERENPDLLASQPSR
RRRIAKGSGHQPAEVDKMLADFQKMRGFMQQMSRGGGMPGMPGMPGMGGMPGMGGMPGMPGMGGMPGMGGGGGGRPGKKM
KPAKKRKGFGEL

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=444, Percent_Identity=31.0810810810811, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI226371618, Length=366, Percent_Identity=32.5136612021858, Blast_Score=225, Evalue=9e-59,
Organism=Homo sapiens, GI295424842, Length=317, Percent_Identity=28.391167192429, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI23308697, Length=317, Percent_Identity=28.391167192429, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI89061728, Length=158, Percent_Identity=37.3417721518987, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1788963, Length=461, Percent_Identity=47.7223427331887, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1789874, Length=230, Percent_Identity=38.2608695652174, Blast_Score=159, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=428, Percent_Identity=31.5420560747664, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI193206261, Length=299, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325345, Length=478, Percent_Identity=33.0543933054393, Blast_Score=271, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6320498, Length=309, Percent_Identity=22.9773462783171, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17647949, Length=446, Percent_Identity=32.7354260089686, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24641198, Length=269, Percent_Identity=27.8810408921933, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 52600; Mature: 52469

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALMFEELSQRFEDAVRGLKGEASISEGNVDSALKDVRRALLDADVSLPVVKSFIAEVR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EKALGADVVRGVSPDQQFIKLVHEELVEVMGGANAPLAKAEQSPTVVLMAGLQGAGKTTA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCH
TAKLGLHLKEQGRRALLVAADTYRPAAIDQLQTLGQQIDVEVFSLGADAKPEAIAEAGLA
HHHHCCEEHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCHHHEECCCCCCHHHHHHHHHH
KGREEGFDTVIVDTAGRLQIDTSMMEEMVRIRSAVAPDEVLLVVDSMIGQEAADLTRSFH
CCHHCCCCEEEEECCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EQVGITGAVLTKMDGDSRGGAALSIRKVSGAPIKFIGTGEKVEALQPFHPERMASRILGM
HHHCCCHHHHEECCCCCCCCCEEEEEECCCCCEEEECCCCHHHHCCCCCHHHHHHHHHCC
GDVLTLVEKAQKEVEIADVEKMQRKLQEASFDFSDFVKQMRLIKRMGSLGGLMKMIPGMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KIDDGMLKQGEAQLKRIEAMIGSMTVQERENPDLLASQPSRRRRIAKGSGHQPAEVDKML
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHH
ADFQKMRGFMQQMSRGGGMPGMPGMPGMGGMPGMGGMPGMPGMGGMPGMGGGGGGRPGKK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MKPAKKRKGFGEL
CCCHHHCCCCCCC
>Mature Secondary Structure 
AALMFEELSQRFEDAVRGLKGEASISEGNVDSALKDVRRALLDADVSLPVVKSFIAEVR
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EKALGADVVRGVSPDQQFIKLVHEELVEVMGGANAPLAKAEQSPTVVLMAGLQGAGKTTA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCH
TAKLGLHLKEQGRRALLVAADTYRPAAIDQLQTLGQQIDVEVFSLGADAKPEAIAEAGLA
HHHHCCEEHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCHHHEECCCCCCHHHHHHHHHH
KGREEGFDTVIVDTAGRLQIDTSMMEEMVRIRSAVAPDEVLLVVDSMIGQEAADLTRSFH
CCHHCCCCEEEEECCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EQVGITGAVLTKMDGDSRGGAALSIRKVSGAPIKFIGTGEKVEALQPFHPERMASRILGM
HHHCCCHHHHEECCCCCCCCCEEEEEECCCCCEEEECCCCHHHHCCCCCHHHHHHHHHCC
GDVLTLVEKAQKEVEIADVEKMQRKLQEASFDFSDFVKQMRLIKRMGSLGGLMKMIPGMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KIDDGMLKQGEAQLKRIEAMIGSMTVQERENPDLLASQPSRRRRIAKGSGHQPAEVDKML
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHH
ADFQKMRGFMQQMSRGGGMPGMPGMPGMGGMPGMGGMPGMPGMGGMPGMGGGGGGRPGKK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MKPAKKRKGFGEL
CCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]