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The map label for this gene is ilvA [H]

Identifier: 148242490

GI number: 148242490

Start: 1238882

End: 1240456

Strand: Direct

Name: ilvA [H]

Synonym: SynRCC307_1391

Alternate gene names: 148242490

Gene position: 1238882-1240456 (Clockwise)

Preceding gene: 148242487

Following gene: 148242491

Centisome position: 55.68

GC content: 62.67

Gene sequence:

>1575_bases
ATGGCATCAACGGCAGCAAACCGGGAGGATGGAGGCAATCAAGACCAGGTCATGGAGGGTTACCTGCAGCGGATCCTGCG
CGCCAGGGTCTATGAGGTGGCCCGCGAAACGCCACTGGAGCCAGCCACGCGCCTATCGCAGCGGCTGGGCCATTCGGTGC
TGCTCAAACGCGAAGACCTGCAACCGGTTTTCTCCTTCAAGCTGCGGGGCGCCTTCAACAAGATGGTGCAGCTGCCCGCC
GAACAGCTGCAGCGCGGGGTCATTGCAGCCAGTGCCGGCAACCATGCCCAGGGCGTGGCCTTGGCCGCCGAGCGCCTGGG
CTGCTCGGCGGTGATCGTGATGCCGGTGACAACGCCGCGCACCAAGGTTGAAGCGGTGCGTAGCCGCGGAGCTGAAGTGG
TGCTCCATGGCGACAGCTTTGACGCCGCCCAGGCCCAGGCCCGAATCCTGGAGCAGGAGCGGGGGCTGTGTTTTATCCAT
CCCTTCGATGACCCCGAAGTCATCGCTGGGCAAGGAACCATTGGCATGGAAATCCTGCGCCAATGCAATGAACCACCGGC
GGCGATCTACCTGGCCGTGGGGGGAGGGGGGCTGATTGCTGGGGTTGGCGCCTACGTCAAAGCCCTCTGGCCAAATGTTC
AGATCATTGGCGTCGAACCGCAGGATGCCGATGCCATGACCCGCTCGCTCGCAGCCGGCGAGCGCCAAAGGCTCGAGCAG
GTTGGGCTGTTTGCCGATGGCGTGGCTGTGCGGGAAGTGGGGGAAGAAACCTTTCGCGTGGCGCAACAGGTGGTGGACCG
GATGGTGACGGTCGATAGCGATGCCATCTGCGCCGCCATCAAAGACGTCTTTGAAGACACCCGCTCAATCCTTGAACCGG
CTGGAGCCCTTGCTGTGGCTGGCTTGAAAGCCGACGCGGCCCGTTGGCCCCCGGGCAGCGCCTTGGTGGCGGTGGCCTGC
GGCGCCAACATGAATTTCGAGCGGCTGCGCTTTGTGGCCGAACGGGCGGAATTGGGCGAGCAACGCGAAGCGATGCTGGC
CGTGGAAATTCCTGAGCAGCCCGGCAGCCTGCGGCAGTTCTGCCGTTTGCTTGGCAGTCACAGCCTGACGGAATTCAGTT
ATCGCCAGGCCCGCGGGCACCGGGCACAAATCTTCGTGGGGGTGGAGACCAGCAACCGCCAAGACGCCATGGCATTAATG
GCCTTGCTGGAAGAGGGGGGATTCTCCTGCGTGGATCTCTCCAGCAATGAATTGGCCAAATTGCACCTGCGCCACATGGT
GGGCGGGCGGCTACCAGAAGCAGCACCAGGGCAAGACCCAGTCCCTGAAAGGCTCTATCGCTTCGAATTCCCCGAACGCC
CCGGTGCCCTGATGGCGTTTGTGGAAGCCCTTCACCCGGGCTGGACCATCAGCATTTTTCATTACCGAAACCAGGGCTCT
GATGTGGGCCGAATCGTTGTGGGAGTCCAAGTTCCAGCTGAGGAGTTGGAGCAATGGCAGCAGGTTTTGGCTGGGCTGCC
CTTCCAAAGCTGGGAGGAGACCAATAACCCCGCCTATCAGCTTTTCCTGGCCTGA

Upstream 100 bases:

>100_bases
CTGCTCAGACCATGCAATTCATTGGGATGACTCAGCTCGCTGAGATGCATTCGGCTGACGTCCCGTAAGCGACAAATCTA
CAACCCCTTCCCAACGGTTG

Downstream 100 bases:

>100_bases
GGCAAAAACGACCGCTACGTTGCGCCAATGGTCTCAACCGAGCTCTCTCTTCCGGCCCAACTCGAGGCGATCCTCTACCT
CAAGGGGCGCTGCCTGAGCC

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MASTAANREDGGNQDQVMEGYLQRILRARVYEVARETPLEPATRLSQRLGHSVLLKREDLQPVFSFKLRGAFNKMVQLPA
EQLQRGVIAASAGNHAQGVALAAERLGCSAVIVMPVTTPRTKVEAVRSRGAEVVLHGDSFDAAQAQARILEQERGLCFIH
PFDDPEVIAGQGTIGMEILRQCNEPPAAIYLAVGGGGLIAGVGAYVKALWPNVQIIGVEPQDADAMTRSLAAGERQRLEQ
VGLFADGVAVREVGEETFRVAQQVVDRMVTVDSDAICAAIKDVFEDTRSILEPAGALAVAGLKADAARWPPGSALVAVAC
GANMNFERLRFVAERAELGEQREAMLAVEIPEQPGSLRQFCRLLGSHSLTEFSYRQARGHRAQIFVGVETSNRQDAMALM
ALLEEGGFSCVDLSSNELAKLHLRHMVGGRLPEAAPGQDPVPERLYRFEFPERPGALMAFVEALHPGWTISIFHYRNQGS
DVGRIVVGVQVPAEELEQWQQVLAGLPFQSWEETNNPAYQLFLA

Sequences:

>Translated_524_residues
MASTAANREDGGNQDQVMEGYLQRILRARVYEVARETPLEPATRLSQRLGHSVLLKREDLQPVFSFKLRGAFNKMVQLPA
EQLQRGVIAASAGNHAQGVALAAERLGCSAVIVMPVTTPRTKVEAVRSRGAEVVLHGDSFDAAQAQARILEQERGLCFIH
PFDDPEVIAGQGTIGMEILRQCNEPPAAIYLAVGGGGLIAGVGAYVKALWPNVQIIGVEPQDADAMTRSLAAGERQRLEQ
VGLFADGVAVREVGEETFRVAQQVVDRMVTVDSDAICAAIKDVFEDTRSILEPAGALAVAGLKADAARWPPGSALVAVAC
GANMNFERLRFVAERAELGEQREAMLAVEIPEQPGSLRQFCRLLGSHSLTEFSYRQARGHRAQIFVGVETSNRQDAMALM
ALLEEGGFSCVDLSSNELAKLHLRHMVGGRLPEAAPGQDPVPERLYRFEFPERPGALMAFVEALHPGWTISIFHYRNQGS
DVGRIVVGVQVPAEELEQWQQVLAGLPFQSWEETNNPAYQLFLA
>Mature_523_residues
ASTAANREDGGNQDQVMEGYLQRILRARVYEVARETPLEPATRLSQRLGHSVLLKREDLQPVFSFKLRGAFNKMVQLPAE
QLQRGVIAASAGNHAQGVALAAERLGCSAVIVMPVTTPRTKVEAVRSRGAEVVLHGDSFDAAQAQARILEQERGLCFIHP
FDDPEVIAGQGTIGMEILRQCNEPPAAIYLAVGGGGLIAGVGAYVKALWPNVQIIGVEPQDADAMTRSLAAGERQRLEQV
GLFADGVAVREVGEETFRVAQQVVDRMVTVDSDAICAAIKDVFEDTRSILEPAGALAVAGLKADAARWPPGSALVAVACG
ANMNFERLRFVAERAELGEQREAMLAVEIPEQPGSLRQFCRLLGSHSLTEFSYRQARGHRAQIFVGVETSNRQDAMALMA
LLEEGGFSCVDLSSNELAKLHLRHMVGGRLPEAAPGQDPVPERLYRFEFPERPGALMAFVEALHPGWTISIFHYRNQGSD
VGRIVVGVQVPAEELEQWQQVLAGLPFQSWEETNNPAYQLFLA

Specific function: Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=273, Percent_Identity=35.8974358974359, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI33469958, Length=312, Percent_Identity=32.3717948717949, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI19923959, Length=314, Percent_Identity=32.1656050955414, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1790207, Length=506, Percent_Identity=51.1857707509881, Blast_Score=473, Evalue=1e-135,
Organism=Escherichia coli, GI1789505, Length=262, Percent_Identity=40.0763358778626, Blast_Score=167, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71991565, Length=329, Percent_Identity=34.0425531914894, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17537387, Length=324, Percent_Identity=33.9506172839506, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17508781, Length=280, Percent_Identity=30, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17535051, Length=272, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320930, Length=522, Percent_Identity=48.6590038314176, Blast_Score=462, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6322631, Length=302, Percent_Identity=33.4437086092715, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319788, Length=300, Percent_Identity=28, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355833, Length=328, Percent_Identity=34.1463414634146, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24645328, Length=251, Percent_Identity=32.6693227091633, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005787
- InterPro:   IPR001721 [H]

Pfam domain/function: PF00291 PALP; PF00585 Thr_dehydrat_C [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 57032; Mature: 56901

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTAANREDGGNQDQVMEGYLQRILRARVYEVARETPLEPATRLSQRLGHSVLLKREDL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHEEEEHHCC
QPVFSFKLRGAFNKMVQLPAEQLQRGVIAASAGNHAQGVALAAERLGCSAVIVMPVTTPR
CHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCH
TKVEAVRSRGAEVVLHGDSFDAAQAQARILEQERGLCFIHPFDDPEVIAGQGTIGMEILR
HHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCEEECCCCHHHHHHH
QCNEPPAAIYLAVGGGGLIAGVGAYVKALWPNVQIIGVEPQDADAMTRSLAAGERQRLEQ
HCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
VGLFADGVAVREVGEETFRVAQQVVDRMVTVDSDAICAAIKDVFEDTRSILEPAGALAVA
HCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHEEE
GLKADAARWPPGSALVAVACGANMNFERLRFVAERAELGEQREAMLAVEIPEQPGSLRQF
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
CRLLGSHSLTEFSYRQARGHRAQIFVGVETSNRQDAMALMALLEEGGFSCVDLSSNELAK
HHHHCCCCCHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHHH
LHLRHMVGGRLPEAAPGQDPVPERLYRFEFPERPGALMAFVEALHPGWTISIFHYRNQGS
HHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCC
DVGRIVVGVQVPAEELEQWQQVLAGLPFQSWEETNNPAYQLFLA
CCCEEEEEEECCHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEC
>Mature Secondary Structure 
ASTAANREDGGNQDQVMEGYLQRILRARVYEVARETPLEPATRLSQRLGHSVLLKREDL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHEEEEHHCC
QPVFSFKLRGAFNKMVQLPAEQLQRGVIAASAGNHAQGVALAAERLGCSAVIVMPVTTPR
CHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCH
TKVEAVRSRGAEVVLHGDSFDAAQAQARILEQERGLCFIHPFDDPEVIAGQGTIGMEILR
HHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCEEECCCCHHHHHHH
QCNEPPAAIYLAVGGGGLIAGVGAYVKALWPNVQIIGVEPQDADAMTRSLAAGERQRLEQ
HCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
VGLFADGVAVREVGEETFRVAQQVVDRMVTVDSDAICAAIKDVFEDTRSILEPAGALAVA
HCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHEEE
GLKADAARWPPGSALVAVACGANMNFERLRFVAERAELGEQREAMLAVEIPEQPGSLRQF
CCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
CRLLGSHSLTEFSYRQARGHRAQIFVGVETSNRQDAMALMALLEEGGFSCVDLSSNELAK
HHHHCCCCCHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHHH
LHLRHMVGGRLPEAAPGQDPVPERLYRFEFPERPGALMAFVEALHPGWTISIFHYRNQGS
HHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCC
DVGRIVVGVQVPAEELEQWQQVLAGLPFQSWEETNNPAYQLFLA
CCCEEEEEEECCHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA