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The map label for this gene is uvrC [H]

Identifier: 148242296

GI number: 148242296

Start: 1054963

End: 1056915

Strand: Direct

Name: uvrC [H]

Synonym: SynRCC307_1197

Alternate gene names: 148242296

Gene position: 1054963-1056915 (Clockwise)

Preceding gene: 148242293

Following gene: 148242298

Centisome position: 47.42

GC content: 59.19

Gene sequence:

>1953_bases
TTGGGGCTGCCGGCCGGAAAAGAACCGCTCATTGAAGACAGCCAGCGGTTGGAAACGCTGCTGCGCAATCTCCCTGTTGA
ACCTGGCTGTTACCTGATGCGCGATCGCGACGATCGCATCCTTTACATCGGTAAATCCAAGAAGCTGCGTAGCCGTGTCC
GCAGCTATTTCCGTGGTGGCAATCCCATCAGCCCACGGATCCGCTTGATGGTGCGTCAAGTGGTGGACATCGAGTTCATC
GTCACCGACAGCGAGGCTGAAGCCCTAGCGCTGGAATCAAATCTGATTAAAAACCACCAGCCGCACTTCAACGTGCTGTT
GAAAGACGACAAGAAATACCCCTACCTCTGCATCACCTGGAGTGAGGATTACCCAAGGATTTTTATCACCAGACGGCGGC
GTTTTCGCAGCCCTTTGGATCGCTTTTATGGGCCCTATGTCGATGTGGGCCTGTTAAGGCGCACGCTGTCTGTGGTCAAG
CGGGTGTTCCCCTTGCGGCAACGGCCCCAGCCACTGCATAAAGACCGCACCTGTCTGAACTACGACATTGGTCGCTGCCC
TGGGGTGTGTCAGGAAAAAATCAGCCCTGCCGATTACCAGCAAATCCTGCGCAAGGTGTCGATGGTGTTTCAGGGTCGCA
ATGAGGAATTGCAGAACCTTCTTCAGCAACAGATGGTGCGCTATTCCGAGCGACTCGACTTTGAAGCCGCTGCTCGGGTT
CGCGACCAGCTTCAGGGCTTGGAGTTGCTCACGGCTGATCAGAAGGTGGCGCTCCCCGATGCCAGTGTCAGCCGCGATGT
GATTGCCCTAGCTGCCGACGACCGCGTCGCTGCAGTTCAACTGTTCCAGGTCAGGGCGGGCAAGTTGGTGGGTCGTTTGG
GCTTCACCGCCGATGCAGAGGCCGCTGAGCCTGGCGCCATCTTGCAGAGGGTTTTGGAGGAGCACTACAGCCAGCTGGAT
CCCGTGGAATTGCCAGCTGAAGTGTTGCTGCAACATCCACTGCCAGAGCAAGAACTTCTGGAGGCATGGCTGCGTGATCG
CCGGGGCCGCAAGGTGATCTTGCAGGTGCCGCAACGGCAGCAAAAGGCCGATCTCATTGAGATGGTGGAGCGCAATGCGG
GCTTTGAGCTGGCCCGCGCTCAGCGCGGCGCCGAGCAGCAGCAGCTCTCCACAGAAGATCTGGCCCAGTTGCTCGAGCTC
GAGCATCCACCGCGGCGCATTGAGGGCTACGACATCAGCCACATCCAAGGCAGTGATGCGGTGGCCTCCCAAGTGGTGTT
CATCGATGGCCTCCCGGCGAAGCAGCACTACCGCAAATACAAGATCCGCAGCAGCAGCATCCGCTCTGGCCATAGCGATG
ACTTCATGGCCATGGCGGAAATCATGCGGCGCCGATTTCGGCGTTGGAGCCAAGCCAAGGCCACTGGCGCCAACCTCTCT
GAGCTGCGCCAACGACGCGGCTCAGCCCTGCAAACCGATGGATTCACCGATTGGCCCGATGTGGTGATGATCGATGGCGG
AAAAGGCCAGCTGTCTGCCGTGATGGAGGCGCTGCGGGAGCTGGATCTGGCTGACGAACTGGTGGTGTGTTCCTTGGCCA
AACAACGGGAGGAAGTGTTTCGGCCAGGAGCCAGCCAGCCGCTGGAGAGCGAGGCCGATCAGCTCGGTGTGCAGCTGCTG
AGGCGCCTGCGGGATGAAGCGCACCGTTTTGCCGTGAGCTTCCACAGGCAGCAACGGGGTGAACGGATGAAACGCTCACG
CCTGAGCGACATCCCAGGACTTGGTCCGAAGCGAGTCAAAGATTTGCTCGCCCATTTCCGCTCGATCGATGCGATCCAGC
TGGCCAGTGCAGAGACGATCGCGGAATGTCCAGGGGTGGGGCCTGCCTTGGCGTTACAAATCCACCAGTTCTTTCATCCG
CAAGCCGAAGCCGATGCTCAGGAAACCGGTTGA

Upstream 100 bases:

>100_bases
GACCAAAGGTCACCGGATCAAAGCTGCCGGGATACAGCGCACGCATGGATTCAGGCGAGCTCTCCCTAGAGTGCCCCAGC
ACGTCGAGGCTGTTCGCCAG

Downstream 100 bases:

>100_bases
GGCCGTTGCAGCAGGTCCATCAAGTGCTCCGGTGATTTGTAGCGGCCTGGCAGTGAGCGATGCAGCAGGGCCAACCGATC
CCAGCAGAGGGAGCGCTTGA

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MGLPAGKEPLIEDSQRLETLLRNLPVEPGCYLMRDRDDRILYIGKSKKLRSRVRSYFRGGNPISPRIRLMVRQVVDIEFI
VTDSEAEALALESNLIKNHQPHFNVLLKDDKKYPYLCITWSEDYPRIFITRRRRFRSPLDRFYGPYVDVGLLRRTLSVVK
RVFPLRQRPQPLHKDRTCLNYDIGRCPGVCQEKISPADYQQILRKVSMVFQGRNEELQNLLQQQMVRYSERLDFEAAARV
RDQLQGLELLTADQKVALPDASVSRDVIALAADDRVAAVQLFQVRAGKLVGRLGFTADAEAAEPGAILQRVLEEHYSQLD
PVELPAEVLLQHPLPEQELLEAWLRDRRGRKVILQVPQRQQKADLIEMVERNAGFELARAQRGAEQQQLSTEDLAQLLEL
EHPPRRIEGYDISHIQGSDAVASQVVFIDGLPAKQHYRKYKIRSSSIRSGHSDDFMAMAEIMRRRFRRWSQAKATGANLS
ELRQRRGSALQTDGFTDWPDVVMIDGGKGQLSAVMEALRELDLADELVVCSLAKQREEVFRPGASQPLESEADQLGVQLL
RRLRDEAHRFAVSFHRQQRGERMKRSRLSDIPGLGPKRVKDLLAHFRSIDAIQLASAETIAECPGVGPALALQIHQFFHP
QAEADAQETG

Sequences:

>Translated_650_residues
MGLPAGKEPLIEDSQRLETLLRNLPVEPGCYLMRDRDDRILYIGKSKKLRSRVRSYFRGGNPISPRIRLMVRQVVDIEFI
VTDSEAEALALESNLIKNHQPHFNVLLKDDKKYPYLCITWSEDYPRIFITRRRRFRSPLDRFYGPYVDVGLLRRTLSVVK
RVFPLRQRPQPLHKDRTCLNYDIGRCPGVCQEKISPADYQQILRKVSMVFQGRNEELQNLLQQQMVRYSERLDFEAAARV
RDQLQGLELLTADQKVALPDASVSRDVIALAADDRVAAVQLFQVRAGKLVGRLGFTADAEAAEPGAILQRVLEEHYSQLD
PVELPAEVLLQHPLPEQELLEAWLRDRRGRKVILQVPQRQQKADLIEMVERNAGFELARAQRGAEQQQLSTEDLAQLLEL
EHPPRRIEGYDISHIQGSDAVASQVVFIDGLPAKQHYRKYKIRSSSIRSGHSDDFMAMAEIMRRRFRRWSQAKATGANLS
ELRQRRGSALQTDGFTDWPDVVMIDGGKGQLSAVMEALRELDLADELVVCSLAKQREEVFRPGASQPLESEADQLGVQLL
RRLRDEAHRFAVSFHRQQRGERMKRSRLSDIPGLGPKRVKDLLAHFRSIDAIQLASAETIAECPGVGPALALQIHQFFHP
QAEADAQETG
>Mature_649_residues
GLPAGKEPLIEDSQRLETLLRNLPVEPGCYLMRDRDDRILYIGKSKKLRSRVRSYFRGGNPISPRIRLMVRQVVDIEFIV
TDSEAEALALESNLIKNHQPHFNVLLKDDKKYPYLCITWSEDYPRIFITRRRRFRSPLDRFYGPYVDVGLLRRTLSVVKR
VFPLRQRPQPLHKDRTCLNYDIGRCPGVCQEKISPADYQQILRKVSMVFQGRNEELQNLLQQQMVRYSERLDFEAAARVR
DQLQGLELLTADQKVALPDASVSRDVIALAADDRVAAVQLFQVRAGKLVGRLGFTADAEAAEPGAILQRVLEEHYSQLDP
VELPAEVLLQHPLPEQELLEAWLRDRRGRKVILQVPQRQQKADLIEMVERNAGFELARAQRGAEQQQLSTEDLAQLLELE
HPPRRIEGYDISHIQGSDAVASQVVFIDGLPAKQHYRKYKIRSSSIRSGHSDDFMAMAEIMRRRFRRWSQAKATGANLSE
LRQRRGSALQTDGFTDWPDVVMIDGGKGQLSAVMEALRELDLADELVVCSLAKQREEVFRPGASQPLESEADQLGVQLLR
RLRDEAHRFAVSFHRQQRGERMKRSRLSDIPGLGPKRVKDLLAHFRSIDAIQLASAETIAECPGVGPALALQIHQFFHPQ
AEADAQETG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=637, Percent_Identity=32.6530612244898, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI1788037, Length=203, Percent_Identity=31.5270935960591, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 74138; Mature: 74007

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLPAGKEPLIEDSQRLETLLRNLPVEPGCYLMRDRDDRILYIGKSKKLRSRVRSYFRGG
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHCCC
NPISPRIRLMVRQVVDIEFIVTDSEAEALALESNLIKNHQPHFNVLLKDDKKYPYLCITW
CCCCHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEE
SEDYPRIFITRRRRFRSPLDRFYGPYVDVGLLRRTLSVVKRVFPLRQRPQPLHKDRTCLN
CCCCCCHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEC
YDIGRCPGVCQEKISPADYQQILRKVSMVFQGRNEELQNLLQQQMVRYSERLDFEAAARV
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
RDQLQGLELLTADQKVALPDASVSRDVIALAADDRVAAVQLFQVRAGKLVGRLGFTADAE
HHHHCCCHHEECCCCEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC
AAEPGAILQRVLEEHYSQLDPVELPAEVLLQHPLPEQELLEAWLRDRRGRKVILQVPQRQ
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCHH
QKADLIEMVERNAGFELARAQRGAEQQQLSTEDLAQLLELEHPPRRIEGYDISHIQGSDA
HHHHHHHHHHHCCCCHHHHHHCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
VASQVVFIDGLPAKQHYRKYKIRSSSIRSGHSDDFMAMAEIMRRRFRRWSQAKATGANLS
HHHEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
ELRQRRGSALQTDGFTDWPDVVMIDGGKGQLSAVMEALRELDLADELVVCSLAKQREEVF
HHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RPGASQPLESEADQLGVQLLRRLRDEAHRFAVSFHRQQRGERMKRSRLSDIPGLGPKRVK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DLLAHFRSIDAIQLASAETIAECPGVGPALALQIHQFFHPQAEADAQETG
HHHHHHHCCCHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GLPAGKEPLIEDSQRLETLLRNLPVEPGCYLMRDRDDRILYIGKSKKLRSRVRSYFRGG
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHCCC
NPISPRIRLMVRQVVDIEFIVTDSEAEALALESNLIKNHQPHFNVLLKDDKKYPYLCITW
CCCCHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEE
SEDYPRIFITRRRRFRSPLDRFYGPYVDVGLLRRTLSVVKRVFPLRQRPQPLHKDRTCLN
CCCCCCHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEC
YDIGRCPGVCQEKISPADYQQILRKVSMVFQGRNEELQNLLQQQMVRYSERLDFEAAARV
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
RDQLQGLELLTADQKVALPDASVSRDVIALAADDRVAAVQLFQVRAGKLVGRLGFTADAE
HHHHCCCHHEECCCCEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC
AAEPGAILQRVLEEHYSQLDPVELPAEVLLQHPLPEQELLEAWLRDRRGRKVILQVPQRQ
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCHH
QKADLIEMVERNAGFELARAQRGAEQQQLSTEDLAQLLELEHPPRRIEGYDISHIQGSDA
HHHHHHHHHHHCCCCHHHHHHCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
VASQVVFIDGLPAKQHYRKYKIRSSSIRSGHSDDFMAMAEIMRRRFRRWSQAKATGANLS
HHHEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
ELRQRRGSALQTDGFTDWPDVVMIDGGKGQLSAVMEALRELDLADELVVCSLAKQREEVF
HHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RPGASQPLESEADQLGVQLLRRLRDEAHRFAVSFHRQQRGERMKRSRLSDIPGLGPKRVK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DLLAHFRSIDAIQLASAETIAECPGVGPALALQIHQFFHPQAEADAQETG
HHHHHHHCCCHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA