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The map label for this gene is glcK [H]

Identifier: 148242024

GI number: 148242024

Start: 850655

End: 851572

Strand: Direct

Name: glcK [H]

Synonym: SynRCC307_0925

Alternate gene names: 148242024

Gene position: 850655-851572 (Clockwise)

Preceding gene: 148242023

Following gene: 148242025

Centisome position: 38.23

GC content: 65.58

Gene sequence:

>918_bases
GTGGTGGTGATGGCGAAGCCGCACCGTCAGGTGATCGGGGTGGATATCGGTGGCACTGGCCTCAAGCTGGGTCGTTTTGA
TAGCGACGGCCAGCTCTTGGCGGAGCAGCTCTGCCCGACACCCCAACCACCCGCCCCCGGTGCCATCACAACGGCGCTGG
TGGAAGCCATTGAGGCCCTTGATCCAGAGCGTCAAGCCGATGCGGTTGGTGTGGGGCTGCCCGGCCCGATGGACCGCAGC
GCCCGGGTGGCTCAGGTCTGCATCAATCTCCCGGGTTGGCAGCACGTTCCGTTGGCCGAGTGGCTGGAGGCACGCCTGCA
GCGCCCGGTCACGTTGGCCAACGATGGCAATTGCGCTGTGCTCGGTGAGCAGTGGCTTGGCGCTGCCAAAGGAATCGATG
ACGTGGTGCTGTTGACCCTGGGCACCGGCGTTGGTGGCGGGGTGATCCTTGGCGGCCAGCTCTTTCTTGGTCGCCGCGGT
GCTGCCGCTGAACCTGGATTGATTGGCCTGGATCCGGCAGGCCCGCCATGCAACAGCGGCAACAACGGTTCGATCGAGAC
GTTTTGCAGCATTGGTGCCCTCACCCGTTGGGCTGGCTGCCCCCCCGATGAGCTCTCCAGGCGCGCCACAAACGGCGATG
CGGAAGCCCTTGAGGCTTGGCAGCGCTATGGCCAGCTTTTGGGCTGCGGCATCAGCTCGTTGGTCTATGCCTTCACCCCC
GAGCGCGTGTTGTTGGGGGGCGGCCTCAGCGCTGCATTTCCCTTTTTTGCCGGCAGTCTTCAGCAGGAGGTGGAGAGCCG
AGTGCTGGCTCCAAGCCGCCAGGATCTGGTGATTGCACCGGCCAGCTTGGGCAATGGGGCTGGCCGCTTGGGCGCGGCTC
GCTTGGCGTTGGAGCGTCTGCCAGGCCGCCAGGGATGA

Upstream 100 bases:

>100_bases
TGGGTGTGCAGGGCGCCCTCGACCAACAGGGGCGCTGGCAGGGACAGCTGCAATTGTTCTTCCGCTTCTAGCCCTGCTCA
GGCTTAATGGAGGCAGTGGA

Downstream 100 bases:

>100_bases
TGCATGGCAGTCCCCCTGCCCAGGCGTTGAATCAGGCCGTTCCCGATCCCTCCCCTGAACTGCTGGCCCGCGCTTCGAGC
CTGAGGCGCCATGCCATTGA

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MVVMAKPHRQVIGVDIGGTGLKLGRFDSDGQLLAEQLCPTPQPPAPGAITTALVEAIEALDPERQADAVGVGLPGPMDRS
ARVAQVCINLPGWQHVPLAEWLEARLQRPVTLANDGNCAVLGEQWLGAAKGIDDVVLLTLGTGVGGGVILGGQLFLGRRG
AAAEPGLIGLDPAGPPCNSGNNGSIETFCSIGALTRWAGCPPDELSRRATNGDAEALEAWQRYGQLLGCGISSLVYAFTP
ERVLLGGGLSAAFPFFAGSLQQEVESRVLAPSRQDLVIAPASLGNGAGRLGAARLALERLPGRQG

Sequences:

>Translated_305_residues
MVVMAKPHRQVIGVDIGGTGLKLGRFDSDGQLLAEQLCPTPQPPAPGAITTALVEAIEALDPERQADAVGVGLPGPMDRS
ARVAQVCINLPGWQHVPLAEWLEARLQRPVTLANDGNCAVLGEQWLGAAKGIDDVVLLTLGTGVGGGVILGGQLFLGRRG
AAAEPGLIGLDPAGPPCNSGNNGSIETFCSIGALTRWAGCPPDELSRRATNGDAEALEAWQRYGQLLGCGISSLVYAFTP
ERVLLGGGLSAAFPFFAGSLQQEVESRVLAPSRQDLVIAPASLGNGAGRLGAARLALERLPGRQG
>Mature_305_residues
MVVMAKPHRQVIGVDIGGTGLKLGRFDSDGQLLAEQLCPTPQPPAPGAITTALVEAIEALDPERQADAVGVGLPGPMDRS
ARVAQVCINLPGWQHVPLAEWLEARLQRPVTLANDGNCAVLGEQWLGAAKGIDDVVLLTLGTGVGGGVILGGQLFLGRRG
AAAEPGLIGLDPAGPPCNSGNNGSIETFCSIGALTRWAGCPPDELSRRATNGDAEALEAWQRYGQLLGCGISSLVYAFTP
ERVLLGGGLSAAFPFFAGSLQQEVESRVLAPSRQDLVIAPASLGNGAGRLGAARLALERLPGRQG

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=266, Percent_Identity=30.8270676691729, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI298566325, Length=266, Percent_Identity=30.8270676691729, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI190014632, Length=266, Percent_Identity=30.8270676691729, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4885285, Length=266, Percent_Identity=30.8270676691729, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786891, Length=305, Percent_Identity=25.2459016393443, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787363, Length=304, Percent_Identity=33.2236842105263, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI87081733, Length=299, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787878, Length=248, Percent_Identity=27.4193548387097, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790522, Length=306, Percent_Identity=30.3921568627451, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87082230, Length=252, Percent_Identity=30.1587301587302, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 31441; Mature: 31441

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVMAKPHRQVIGVDIGGTGLKLGRFDSDGQLLAEQLCPTPQPPAPGAITTALVEAIEAL
CEEECCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
DPERQADAVGVGLPGPMDRSARVAQVCINLPGWQHVPLAEWLEARLQRPVTLANDGNCAV
CCCHHHCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCCEEE
LGEQWLGAAKGIDDVVLLTLGTGVGGGVILGGQLFLGRRGAAAEPGLIGLDPAGPPCNSG
ECHHHHHHHCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEECCCCCCCCCCC
NNGSIETFCSIGALTRWAGCPPDELSRRATNGDAEALEAWQRYGQLLGCGISSLVYAFTP
CCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCC
ERVLLGGGLSAAFPFFAGSLQQEVESRVLAPSRQDLVIAPASLGNGAGRLGAARLALERL
CEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHC
PGRQG
CCCCC
>Mature Secondary Structure
MVVMAKPHRQVIGVDIGGTGLKLGRFDSDGQLLAEQLCPTPQPPAPGAITTALVEAIEAL
CEEECCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
DPERQADAVGVGLPGPMDRSARVAQVCINLPGWQHVPLAEWLEARLQRPVTLANDGNCAV
CCCHHHCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCCEEE
LGEQWLGAAKGIDDVVLLTLGTGVGGGVILGGQLFLGRRGAAAEPGLIGLDPAGPPCNSG
ECHHHHHHHCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEECCCCCCCCCCC
NNGSIETFCSIGALTRWAGCPPDELSRRATNGDAEALEAWQRYGQLLGCGISSLVYAFTP
CCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCC
ERVLLGGGLSAAFPFFAGSLQQEVESRVLAPSRQDLVIAPASLGNGAGRLGAARLALERL
CEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHC
PGRQG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]