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The map label for this gene is crtE [H]

Identifier: 148241850

GI number: 148241850

Start: 679922

End: 680824

Strand: Direct

Name: crtE [H]

Synonym: SynRCC307_0751

Alternate gene names: 148241850

Gene position: 679922-680824 (Clockwise)

Preceding gene: 148241849

Following gene: 148241851

Centisome position: 30.56

GC content: 62.57

Gene sequence:

>903_bases
ATGACTGCTGTGGTGGCCAACGGCTTTGATTTCTCTCATTACCTCGAGGCTGGCCGCCTCAAGGTGGAGCAGGCGCTGGA
TTCTTCCCTTGGCCCTGAGCGGCCGGAATCGCTGCGGGAAGCCATGCGCTATTCCCTGCTCGCTGGCGGTAAGCGTTTAC
GGCCCATCCTGTGTCTCGCCAGCTGTGAGCTCGCCGGTGGCGATGCCTCGCTGGCTTTGCCCACCGCGACGGCGCTGGAG
ATGATCCACACCATGTCGCTGATCCATGACGATCTGCCGGCCATGGACAACGACGATCTGCGCCGCGGCCGGCCCACCAA
TCACAAGGTGTATGGCGATGCCACAGCGATCTTGGCTGGCGATGCTTTGCTCACCCGCGCCTTTGAGATGGTGGCGCTGC
GCAGCCCCGATGTTCCTGCCGAGCGCCTCTTGAAGGTGATTGGTGAGTTGTCGTTGGCGGCGGGTGCTCCCGGCTTGGTG
GGCGGGCAAATCGTTGATTTGGCTAGCGAAGGGGTGGAGGTGGACCTCGACACCCTCGAATACATCCACCTGCACAAAAC
CGGAGCATTGCTGCAGGCCTCGGTCTTGAGCGGAGCGCTGATTGCCGGGGCGGATGACACGTTGCTGGAGGCCCTGCGCA
CCTACTCCAGGGCGATTGGTCTGGCCTTCCAGATCATCGATGACATCCTTGATGTCACCGCTAGCAGCGAAGTGCTGGGC
AAGACCGCAGGCAAAGATCTCACGGCTGATAAGACCACCTACCCCAAGCTGCTGGGCCTCGAGGAATCCAAGGCTCGGGC
TGAGTCGCTGGTCAAGGAGGCCTGCGGGGTTCTGAACCCCTGGAGCGACAAGGCCCAGCCCCTGCTGGCCCTGGCGGGTT
ACATCACCTCCCGCGATCGATGA

Upstream 100 bases:

>100_bases
GTGGTGGAACTGCCCTCGGCGTTGTTCGCTCTGTTGCAGCAGGTGCTGGGTGGCCCGCCGTTGAGAGACAATCCCTGCAG
CTGAGGCGATCTGCCGTTTC

Downstream 100 bases:

>100_bases
GTCAGCCATTTGTTCAGCTGCTCGATAACGGCCCCTTGGCCTGGGGCCTTGCAGCCTGTGGCTTGGCGCAGCTCTCCAAA
CTCTTGATTGAGTTAGTGGT

Product: geranylgeranyl pyrophosphate synthase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTAVVANGFDFSHYLEAGRLKVEQALDSSLGPERPESLREAMRYSLLAGGKRLRPILCLASCELAGGDASLALPTATALE
MIHTMSLIHDDLPAMDNDDLRRGRPTNHKVYGDATAILAGDALLTRAFEMVALRSPDVPAERLLKVIGELSLAAGAPGLV
GGQIVDLASEGVEVDLDTLEYIHLHKTGALLQASVLSGALIAGADDTLLEALRTYSRAIGLAFQIIDDILDVTASSEVLG
KTAGKDLTADKTTYPKLLGLEESKARAESLVKEACGVLNPWSDKAQPLLALAGYITSRDR

Sequences:

>Translated_300_residues
MTAVVANGFDFSHYLEAGRLKVEQALDSSLGPERPESLREAMRYSLLAGGKRLRPILCLASCELAGGDASLALPTATALE
MIHTMSLIHDDLPAMDNDDLRRGRPTNHKVYGDATAILAGDALLTRAFEMVALRSPDVPAERLLKVIGELSLAAGAPGLV
GGQIVDLASEGVEVDLDTLEYIHLHKTGALLQASVLSGALIAGADDTLLEALRTYSRAIGLAFQIIDDILDVTASSEVLG
KTAGKDLTADKTTYPKLLGLEESKARAESLVKEACGVLNPWSDKAQPLLALAGYITSRDR
>Mature_299_residues
TAVVANGFDFSHYLEAGRLKVEQALDSSLGPERPESLREAMRYSLLAGGKRLRPILCLASCELAGGDASLALPTATALEM
IHTMSLIHDDLPAMDNDDLRRGRPTNHKVYGDATAILAGDALLTRAFEMVALRSPDVPAERLLKVIGELSLAAGAPGLVG
GQIVDLASEGVEVDLDTLEYIHLHKTGALLQASVLSGALIAGADDTLLEALRTYSRAIGLAFQIIDDILDVTASSEVLGK
TAGKDLTADKTTYPKLLGLEESKARAESLVKEACGVLNPWSDKAQPLLALAGYITSRDR

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=237, Percent_Identity=29.957805907173, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1786623, Length=299, Percent_Identity=45.4849498327759, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1789578, Length=234, Percent_Identity=32.0512820512821, Blast_Score=117, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17505681, Length=252, Percent_Identity=29.3650793650794, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319475, Length=233, Percent_Identity=30.4721030042918, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24651612, Length=250, Percent_Identity=32, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 31814; Mature: 31683

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVVANGFDFSHYLEAGRLKVEQALDSSLGPERPESLREAMRYSLLAGGKRLRPILCLA
CCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
SCELAGGDASLALPTATALEMIHTMSLIHDDLPAMDNDDLRRGRPTNHKVYGDATAILAG
HCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEECCHHHHHHH
DALLTRAFEMVALRSPDVPAERLLKVIGELSLAAGAPGLVGGQIVDLASEGVEVDLDTLE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEHHHHH
YIHLHKTGALLQASVLSGALIAGADDTLLEALRTYSRAIGLAFQIIDDILDVTASSEVLG
HHHHHHHHHHHHHHHHHCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KTAGKDLTADKTTYPKLLGLEESKARAESLVKEACGVLNPWSDKAQPLLALAGYITSRDR
HHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAVVANGFDFSHYLEAGRLKVEQALDSSLGPERPESLREAMRYSLLAGGKRLRPILCLA
CEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
SCELAGGDASLALPTATALEMIHTMSLIHDDLPAMDNDDLRRGRPTNHKVYGDATAILAG
HCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEECCHHHHHHH
DALLTRAFEMVALRSPDVPAERLLKVIGELSLAAGAPGLVGGQIVDLASEGVEVDLDTLE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEHHHHH
YIHLHKTGALLQASVLSGALIAGADDTLLEALRTYSRAIGLAFQIIDDILDVTASSEVLG
HHHHHHHHHHHHHHHHHCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KTAGKDLTADKTTYPKLLGLEESKARAESLVKEACGVLNPWSDKAQPLLALAGYITSRDR
HHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515931 [H]