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The map label for this gene is ctaB

Identifier: 148241773

GI number: 148241773

Start: 611655

End: 612644

Strand: Direct

Name: ctaB

Synonym: SynRCC307_0674

Alternate gene names: 148241773

Gene position: 611655-612644 (Clockwise)

Preceding gene: 148241772

Following gene: 148241774

Centisome position: 27.49

GC content: 64.55

Gene sequence:

>990_bases
ATGGCTGAAGTGCCCATTGCTGTCCCTGTCTCGATCCGCGACGAGGTCGTTCCCAGTCGCAAGCGGGTCAAGTTGCCGCC
TTGGCTGGAGATTGCCAAGCCACGCCTGATCCCGCTGCTGCTGGCCACCACCCTCGGTGGCATGGCGCTCAGTGAGAGCT
GGCCCCTGCCCTTGCCGCGGCTGGCCTGCACCTTGGGCGGTGGCGCCCTCGCTGCCGCTGCCGCTGGCGTTCTCAATTGC
CTCTGGGAAGAGCAGCTTGATGGCCAAATGCAGCGCACCAGTGGCCGCGCCCTGCCGTCGGGCCGGCTCAGTGGCAGCCA
GGCGTTTCTGATTGCCGTCGCCTTGGCTTGCGGCGCCTCGCTGCTGCTTGTGGCCGGGGTGAACTGCCTGGCTGCTGGCC
TGTCCCTGCTGGGCTTGTGCAGCTATGTGCTGCTCTACACGATTGTTCTCAAGCCCCGCACCACGCGCAACATCGTCATT
GGTGGGGTGGCTGGTGCGATTCCTCCGTTGGTGGGAGCGGCAGCTGCCACCGGCCATGTGGGGCTCGGGGGCTGGTGGTT
GTTTGGCCTGGTGATGCTGTGGACGCCGGCTCATTTTTGGGCTCTCGCCTTGTTGCTCACCGACGACTACCGCTCGGTTG
GCATTCCGATGTTGCCCGTCGTCAAAGGCCCTGAGGTGACCGGCCGCGCCATCAACCGCTACGCCTACGCCACCGTTGCC
GCCAGCCTGCTCGGGGTGCTGACCCTGCCCAGTGGCGGATTGTTCTATGGACTGATGGTGTTGCCCTTCAACGGCCGCCT
GCTGCAGATGGCCCAGCGCCTGGGTGAACTGCCCGATGACAAGCAGCGGGCCAAGGGGCTGTTCCGTTGGTCGATCCTTT
ATCTGTTTGGCATCTGCCTGTTGCTGCTGCTGGCCCGCACGACGATGGCGGCTGATTTCAGCAACCAGCTGATCAGCCTG
CTCACACTGCCGCCTGCATCTGCTTTTTAA

Upstream 100 bases:

>100_bases
CTGGTCACCGTTGGCCACCAATTGGTGGCGGCGTTGTTGATCGCCACCTTCTCGGCGGCTGCCGTCGCCCTACGGCCTGC
TCCATCACCTGCTTTGCGTC

Downstream 100 bases:

>100_bases
GCTGGGCAGACGTTGACAGCCGCCGTGATTCAGCTCGATCAGCTCAGCAAGCGCTATGGGGCCCTGCAGGCCCTCGATGG
GGTGAGCTTGAACGTGCCTG

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAEVPIAVPVSIRDEVVPSRKRVKLPPWLEIAKPRLIPLLLATTLGGMALSESWPLPLPRLACTLGGGALAAAAAGVLNC
LWEEQLDGQMQRTSGRALPSGRLSGSQAFLIAVALACGASLLLVAGVNCLAAGLSLLGLCSYVLLYTIVLKPRTTRNIVI
GGVAGAIPPLVGAAAATGHVGLGGWWLFGLVMLWTPAHFWALALLLTDDYRSVGIPMLPVVKGPEVTGRAINRYAYATVA
ASLLGVLTLPSGGLFYGLMVLPFNGRLLQMAQRLGELPDDKQRAKGLFRWSILYLFGICLLLLLARTTMAADFSNQLISL
LTLPPASAF

Sequences:

>Translated_329_residues
MAEVPIAVPVSIRDEVVPSRKRVKLPPWLEIAKPRLIPLLLATTLGGMALSESWPLPLPRLACTLGGGALAAAAAGVLNC
LWEEQLDGQMQRTSGRALPSGRLSGSQAFLIAVALACGASLLLVAGVNCLAAGLSLLGLCSYVLLYTIVLKPRTTRNIVI
GGVAGAIPPLVGAAAATGHVGLGGWWLFGLVMLWTPAHFWALALLLTDDYRSVGIPMLPVVKGPEVTGRAINRYAYATVA
ASLLGVLTLPSGGLFYGLMVLPFNGRLLQMAQRLGELPDDKQRAKGLFRWSILYLFGICLLLLLARTTMAADFSNQLISL
LTLPPASAF
>Mature_328_residues
AEVPIAVPVSIRDEVVPSRKRVKLPPWLEIAKPRLIPLLLATTLGGMALSESWPLPLPRLACTLGGGALAAAAAGVLNCL
WEEQLDGQMQRTSGRALPSGRLSGSQAFLIAVALACGASLLLVAGVNCLAAGLSLLGLCSYVLLYTIVLKPRTTRNIVIG
GVAGAIPPLVGAAAATGHVGLGGWWLFGLVMLWTPAHFWALALLLTDDYRSVGIPMLPVVKGPEVTGRAINRYAYATVAA
SLLGVLTLPSGGLFYGLMVLPFNGRLLQMAQRLGELPDDKQRAKGLFRWSILYLFGICLLLLLARTTMAADFSNQLISLL
TLPPASAF

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily

Homologues:

Organism=Homo sapiens, GI17921982, Length=260, Percent_Identity=31.9230769230769, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1786631, Length=270, Percent_Identity=31.8518518518519, Blast_Score=124, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71998235, Length=266, Percent_Identity=30.0751879699248, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6325085, Length=215, Percent_Identity=31.1627906976744, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921064, Length=282, Percent_Identity=32.6241134751773, Blast_Score=118, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXX_SYNR3 (A5GRR8)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001226930.1
- STRING:   A5GRR8
- GeneID:   5158699
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_0674
- eggNOG:   COG0109
- HOGENOM:   HBG656003
- OMA:   MALTEGW
- ProtClustDB:   PRK04375
- HAMAP:   MF_00154
- InterPro:   IPR006369
- InterPro:   IPR000537
- PANTHER:   PTHR11048:SF3
- TIGRFAMs:   TIGR01473

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 34724; Mature: 34593

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21f77930)-; HASH(0x22a5e5fc)-; HASH(0x21122b80)-; HASH(0x22a5bd3c)-; HASH(0x21124ce0)-; HASH(0x22a5e98c)-; HASH(0x22b0643c)-;

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVPIAVPVSIRDEVVPSRKRVKLPPWLEIAKPRLIPLLLATTLGGMALSESWPLPLPR
CCCCCEEECCCCHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCEECCCCCCCCHH
LACTLGGGALAAAAAGVLNCLWEEQLDGQMQRTSGRALPSGRLSGSQAFLIAVALACGAS
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
LLLVAGVNCLAAGLSLLGLCSYVLLYTIVLKPRTTRNIVIGGVAGAIPPLVGAAAATGHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHCCCCC
GLGGWWLFGLVMLWTPAHFWALALLLTDDYRSVGIPMLPVVKGPEVTGRAINRYAYATVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ASLLGVLTLPSGGLFYGLMVLPFNGRLLQMAQRLGELPDDKQRAKGLFRWSILYLFGICL
HHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LLLLARTTMAADFSNQLISLLTLPPASAF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure 
AEVPIAVPVSIRDEVVPSRKRVKLPPWLEIAKPRLIPLLLATTLGGMALSESWPLPLPR
CCCCEEECCCCHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCEECCCCCCCCHH
LACTLGGGALAAAAAGVLNCLWEEQLDGQMQRTSGRALPSGRLSGSQAFLIAVALACGAS
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
LLLVAGVNCLAAGLSLLGLCSYVLLYTIVLKPRTTRNIVIGGVAGAIPPLVGAAAATGHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHCCCCC
GLGGWWLFGLVMLWTPAHFWALALLLTDDYRSVGIPMLPVVKGPEVTGRAINRYAYATVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ASLLGVLTLPSGGLFYGLMVLPFNGRLLQMAQRLGELPDDKQRAKGLFRWSILYLFGICL
HHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LLLLARTTMAADFSNQLISLLTLPPASAF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA