Click here to switch to the map view.

The map label for this gene is cobI [H]

Identifier: 148241559

GI number: 148241559

Start: 431976

End: 432695

Strand: Direct

Name: cobI [H]

Synonym: SynRCC307_0460

Alternate gene names: 148241559

Gene position: 431976-432695 (Clockwise)

Preceding gene: 148241557

Following gene: 148241560

Centisome position: 19.42

GC content: 67.5

Gene sequence:

>720_bases
GTGGTGGGGGTGGGCCCGGGAGATCCCGAGTTGATCACCGTGGCGGCTCAGCGCGCCATTGCGGCAGCCACGGTGGTGGC
CTATCCGGTGGCTGCGCTCGAACGGCCTGGGATGGCGGCGCAGATTGCCCAGCCTTGGCTTGTGCCAACACAACGGCGGC
TGCCGCTGCTGTTCCCGATGGTTCAAGAGGCCGAACCACGTCAGAAGGCTTGGCAGCAAGCCGCTAGCGCTGTGGCCGCG
GAAGTGGCCGCTGGTGAGCAGGTGGTGTTTCTCTGCGAGGGGGATTGCTCCCTGTTCGCCAGCTCCAGCTATCTGCTGCT
GGCTCTCAAAAAGGAGGCTCCGGAGCTGTCAGCTCAGGTGATTCCTGGCATCACGGCTGCCTCGGCCACTGCCGCAGCGG
CTTGTTGGCCGTTGGCTTTGCAAGATGAGCAGCTCCAGGTGGTGCCGCTGCCCGATCAGCCCGATCAGGCCCGCCAGCTG
CTGATCGCGGCGCGCGACCAAGGCCAGCCGCTCGTGCTGCTCAAGGTGGGGCGCCGCTGGCGGTGGCTGAGGCCGCTGCT
CGATGAGTTGGAGCTGCTCGAGAGCGCCCTCTATGGGGAGCGGGTGGGCTGGCCGGAGCAATTGGTTTTGCCGGCCGCGG
CGGTGGCGGCCGAGGAGCGCCCTTACTTTTCTCTTGTGCTTCTCAGGCCGGCGTGGCCGGCGGTGCTGCCATGGGCCTGA

Upstream 100 bases:

>100_bases
ATCGTTAATTGGCTCATGAATCAGCCTTGAGCCGGTACGTCAACCTAAGCCGCGAGCCAGGAGTGAATCGCTGACCTCAG
CACATCGTTCAGGACTCACT

Downstream 100 bases:

>100_bases
TCGATCTGCAGCTGGCCGAAGCCACACCCGTCAATGGGCTCTGGAGTGAGCTGGTCGAGCGGCTGGGCGCCGAGCGGGCC
CAGCTGGCGTGCCGCCAAGC

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MVGVGPGDPELITVAAQRAIAAATVVAYPVAALERPGMAAQIAQPWLVPTQRRLPLLFPMVQEAEPRQKAWQQAASAVAA
EVAAGEQVVFLCEGDCSLFASSSYLLLALKKEAPELSAQVIPGITAASATAAAACWPLALQDEQLQVVPLPDQPDQARQL
LIAARDQGQPLVLLKVGRRWRWLRPLLDELELLESALYGERVGWPEQLVLPAAAVAAEERPYFSLVLLRPAWPAVLPWA

Sequences:

>Translated_239_residues
MVGVGPGDPELITVAAQRAIAAATVVAYPVAALERPGMAAQIAQPWLVPTQRRLPLLFPMVQEAEPRQKAWQQAASAVAA
EVAAGEQVVFLCEGDCSLFASSSYLLLALKKEAPELSAQVIPGITAASATAAAACWPLALQDEQLQVVPLPDQPDQARQL
LIAARDQGQPLVLLKVGRRWRWLRPLLDELELLESALYGERVGWPEQLVLPAAAVAAEERPYFSLVLLRPAWPAVLPWA
>Mature_239_residues
MVGVGPGDPELITVAAQRAIAAATVVAYPVAALERPGMAAQIAQPWLVPTQRRLPLLFPMVQEAEPRQKAWQQAASAVAA
EVAAGEQVVFLCEGDCSLFASSSYLLLALKKEAPELSAQVIPGITAASATAAAACWPLALQDEQLQVVPLPDQPDQARQL
LIAARDQGQPLVLLKVGRRWRWLRPLLDELELLESALYGERVGWPEQLVLPAAAVAAEERPYFSLVLLRPAWPAVLPWA

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 25756; Mature: 25756

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGVGPGDPELITVAAQRAIAAATVVAYPVAALERPGMAAQIAQPWLVPTQRRLPLLFPM
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEHHH
VQEAEPRQKAWQQAASAVAAEVAAGEQVVFLCEGDCSLFASSSYLLLALKKEAPELSAQV
HHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCEEEEEEECCCCCCHHHH
IPGITAASATAAAACWPLALQDEQLQVVPLPDQPDQARQLLIAARDQGQPLVLLKVGRRW
CCCCCHHHHHHHHHHCEEEECCCCEEEEECCCCCHHHHHEEHEECCCCCCEEEEECCCCH
RWLRPLLDELELLESALYGERVGWPEQLVLPAAAVAAEERPYFSLVLLRPAWPAVLPWA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MVGVGPGDPELITVAAQRAIAAATVVAYPVAALERPGMAAQIAQPWLVPTQRRLPLLFPM
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEHHH
VQEAEPRQKAWQQAASAVAAEVAAGEQVVFLCEGDCSLFASSSYLLLALKKEAPELSAQV
HHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCEEEEEEECCCCCCHHHH
IPGITAASATAAAACWPLALQDEQLQVVPLPDQPDQARQLLIAARDQGQPLVLLKVGRRW
CCCCCHHHHHHHHHHCEEEECCCCEEEEECCCCCHHHHHEEHEECCCCCCEEEEECCCCH
RWLRPLLDELELLESALYGERVGWPEQLVLPAAAVAAEERPYFSLVLLRPAWPAVLPWA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]