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The map label for this gene is mdtA [H]

Identifier: 148241497

GI number: 148241497

Start: 377461

End: 378549

Strand: Direct

Name: mdtA [H]

Synonym: SynRCC307_0398

Alternate gene names: 148241497

Gene position: 377461-378549 (Clockwise)

Preceding gene: 148241496

Following gene: 148241498

Centisome position: 16.97

GC content: 59.32

Gene sequence:

>1089_bases
GTGGCTGCTGCCAGACGCAACAGGATCAGGCTGTCGGTGATGGTTTGGCTGGCGGTGTTGGCGGGCTGCCAGTCGCCCAA
GCCGCCGGCTGTGCGCGGCCATGTTGAGTTGATTGCTCCCAAGCAGTTCCGCTTTCAGGAGCAGGCCACCTACCAGAGCA
CGCTCGAATCGATCAGCAATGTTGCGATGGCGGCTGAGATTGACGGTCGGATCACCTCGATGCCCATGCAACAGGGCCAA
CAGGTGCAGCCAGGTGACTTGCTGTTCACCCTCGATCAGGTGCAGCAGCGCGCGCAGGTGGATGCAGCAGCTGCAGAGGC
GCGTAAAACCAGGGTCAATGCCAATCGCTACATCTTTCTGAACGACCAGGGCGCCGTTTCCACCAAAGACCGCGACTATT
ACGTCACCCAGGCGATTGAAAGTGCTGATCGGCTCAGGGCCGATCAGGCCACCCTCGATTACAAGAACGTGGTGGCGCCG
ATTGCTGGCCAGGTGGGCAGCATCCAGCACAAGCTCGGATCGGTGGTGAGCCAAGGCGAGACCATCGTCAACATCGTTGA
CAACTCAAAGCTCTGGGTGCGTTTGGACGTGCCATCGGAGCTGGCTTATCGCCTCAGACTCGGCATGCCCGTTGTCTTGA
AAGCACCAGGTTTGCCAGCTGACCTTCCTGAAGGTGAGGTGTCCTTCATCGCTCCCTCGCTGGATCGTAGTAGCCAGACC
GTGCTGGTTAAAGCCACCTTCGATAACCCAAACGGCGTTCTGCGCGATCAACAGCGGGTAGCGGCCGTTCTGAGCTTCGG
CTCGAACTCTTTGTTGTCAGTCCCTGTTGGTGCGGTTTTGCTGCAAGCCGGACAGACCTTTGTGTTTACGGCAGTGCCGG
CAGCCAAGGCGCAGAAACAATTGGGGCGTGAGCTCAAGCCCAAGCCAGCCAAGGGTGATCTCGTTGCTGTCCAAACTCAA
GTGGGCCTTGGCACGCTGCAGGACGGCCGCTATCCGGTCTTGAAAGGACTCGATGGCACCGAAAAAGTGGTGATGGGCAA
CTTGGCGCAGCTGCGCAGCGGCATGGTGCTGCCTGTGACTGGCCAATGA

Upstream 100 bases:

>100_bases
AAGGCCAAGGCGTCTTCGCTCGAGGTGCCTATCTGTCGCCCATTGCGTTGACCCGCTCAAATCCTCGCTTTAGGTTGCGC
CCCATCGAGAGGCACCTCCT

Downstream 100 bases:

>100_bases
GCCTTTCGGACACTTTCATTCGTCGCCCGGTGCTTAGCACCGTGTGCAGCATCTTGATCCTGATGGCCGGGCTGATTTCC
CTGCCGCTGCTGCCGATCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MAAARRNRIRLSVMVWLAVLAGCQSPKPPAVRGHVELIAPKQFRFQEQATYQSTLESISNVAMAAEIDGRITSMPMQQGQ
QVQPGDLLFTLDQVQQRAQVDAAAAEARKTRVNANRYIFLNDQGAVSTKDRDYYVTQAIESADRLRADQATLDYKNVVAP
IAGQVGSIQHKLGSVVSQGETIVNIVDNSKLWVRLDVPSELAYRLRLGMPVVLKAPGLPADLPEGEVSFIAPSLDRSSQT
VLVKATFDNPNGVLRDQQRVAAVLSFGSNSLLSVPVGAVLLQAGQTFVFTAVPAAKAQKQLGRELKPKPAKGDLVAVQTQ
VGLGTLQDGRYPVLKGLDGTEKVVMGNLAQLRSGMVLPVTGQ

Sequences:

>Translated_362_residues
MAAARRNRIRLSVMVWLAVLAGCQSPKPPAVRGHVELIAPKQFRFQEQATYQSTLESISNVAMAAEIDGRITSMPMQQGQ
QVQPGDLLFTLDQVQQRAQVDAAAAEARKTRVNANRYIFLNDQGAVSTKDRDYYVTQAIESADRLRADQATLDYKNVVAP
IAGQVGSIQHKLGSVVSQGETIVNIVDNSKLWVRLDVPSELAYRLRLGMPVVLKAPGLPADLPEGEVSFIAPSLDRSSQT
VLVKATFDNPNGVLRDQQRVAAVLSFGSNSLLSVPVGAVLLQAGQTFVFTAVPAAKAQKQLGRELKPKPAKGDLVAVQTQ
VGLGTLQDGRYPVLKGLDGTEKVVMGNLAQLRSGMVLPVTGQ
>Mature_361_residues
AAARRNRIRLSVMVWLAVLAGCQSPKPPAVRGHVELIAPKQFRFQEQATYQSTLESISNVAMAAEIDGRITSMPMQQGQQ
VQPGDLLFTLDQVQQRAQVDAAAAEARKTRVNANRYIFLNDQGAVSTKDRDYYVTQAIESADRLRADQATLDYKNVVAPI
AGQVGSIQHKLGSVVSQGETIVNIVDNSKLWVRLDVPSELAYRLRLGMPVVLKAPGLPADLPEGEVSFIAPSLDRSSQTV
LVKATFDNPNGVLRDQQRVAAVLSFGSNSLLSVPVGAVLLQAGQTFVFTAVPAAKAQKQLGRELKPKPAKGDLVAVQTQV
GLGTLQDGRYPVLKGLDGTEKVVMGNLAQLRSGMVLPVTGQ

Specific function: The mdtABC tripartite complex confers resistance against novobiocin and deoxycholate [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=271, Percent_Identity=27.6752767527675, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081796, Length=337, Percent_Identity=23.7388724035608, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38986; Mature: 38855

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAARRNRIRLSVMVWLAVLAGCQSPKPPAVRGHVELIAPKQFRFQEQATYQSTLESISN
CCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
VAMAAEIDGRITSMPMQQGQQVQPGDLLFTLDQVQQRAQVDAAAAEARKTRVNANRYIFL
HEEEEECCCCEEECCHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
NDQGAVSTKDRDYYVTQAIESADRLRADQATLDYKNVVAPIAGQVGSIQHKLGSVVSQGE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCC
TIVNIVDNSKLWVRLDVPSELAYRLRLGMPVVLKAPGLPADLPEGEVSFIAPSLDRSSQT
EEEEEECCCEEEEEEECCHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCE
VLVKATFDNPNGVLRDQQRVAAVLSFGSNSLLSVPVGAVLLQAGQTFVFTAVPAAKAQKQ
EEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCEEEEEECCHHHHHHH
LGRELKPKPAKGDLVAVQTQVGLGTLQDGRYPVLKGLDGTEKVVMGNLAQLRSGMVLPVT
HCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHCCHHHHHCCCEEEEC
GQ
CC
>Mature Secondary Structure 
AAARRNRIRLSVMVWLAVLAGCQSPKPPAVRGHVELIAPKQFRFQEQATYQSTLESISN
CCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
VAMAAEIDGRITSMPMQQGQQVQPGDLLFTLDQVQQRAQVDAAAAEARKTRVNANRYIFL
HEEEEECCCCEEECCHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
NDQGAVSTKDRDYYVTQAIESADRLRADQATLDYKNVVAPIAGQVGSIQHKLGSVVSQGE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCC
TIVNIVDNSKLWVRLDVPSELAYRLRLGMPVVLKAPGLPADLPEGEVSFIAPSLDRSSQT
EEEEEECCCEEEEEEECCHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCE
VLVKATFDNPNGVLRDQQRVAAVLSFGSNSLLSVPVGAVLLQAGQTFVFTAVPAAKAQKQ
EEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCEEEEEECCHHHHHHH
LGRELKPKPAKGDLVAVQTQVGLGTLQDGRYPVLKGLDGTEKVVMGNLAQLRSGMVLPVT
HCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHCCHHHHHCCCEEEEC
GQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA