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The map label for this gene is sdcS [H]

Identifier: 147675598

GI number: 147675598

Start: 2899483

End: 2900919

Strand: Reverse

Name: sdcS [H]

Synonym: VC0395_A2740

Alternate gene names: 147675598

Gene position: 2900919-2899483 (Counterclockwise)

Preceding gene: 147674504

Following gene: 147673631

Centisome position: 95.93

GC content: 50.24

Gene sequence:

>1437_bases
TTGAGCCAAGAGGGAAAGCCCATGCCGCAACTGGAACGAGGTCTACTCGTCAAACTCCTGATCTGTTTCTTACTGCCGTT
GGGCGTACTATTGATGCCGATTGATGCAATCCCGATTCAAGATCTCACCTTGGTTCAACACCGTTTACTGGCCATTTTCC
TTCTTGCTGCACTGCTGTGGGTGTTGGAGCCTGTTCCTGTGTTTGCCACGTCGATCCTGATCATTGCCCTTGAACTCGTC
ATGATTTCCGATAAAGGCTTGCATGGCTTTCGAGTGCCCGATCCGCATCATCCGCTCGGTGAACTCCTTAAATACACCGA
TATTTTCAGTGCCTTCTCCTCTCCCATTATCATTTTGTTTATGGGCGGTTTTGCTTTAGCCATCGCCGCATCTAAATACG
AATTGGATAACAACTTAGCACGAGTGCTACTCAAACCTTTTGGCCACCAGCCTAAGTACATCATGCTCGGGTTAATGCTG
ATCACCTCAGTTTTCTCGATGTTTATGTCCAACACAGCGACCACAGTGATGATGTTGGCGCTGCTTGGCCCTATTGTTGC
GTCTGCCCCCAAAGGGGATTTAGGCATCAAAGCTCTGGTGGTATGCATTCCGATTGCGGCCAACACAGGGGGCATCGCAA
CCCCGATCGGCACGCCACCTAACGCTATCGCACTGCAGTATCTAACGGGCGAAAACAGCATTGATTTTCTGTCATGGATG
ATGATGGGATTGCCGTTCGTACTGGTACAACTGACCATCGCTTGGTTCTTACTGCAAAAGCTTTTCCCCTCCTCACAAGC
CACAATGACCTTGAAACTCAAAGGCGAATTTCAACGCGGCTGGCGTGCCATGCTGGTCTACATCACGTTTGCTTTAACCA
TAGTGCTGTGGATGACCACCTCATGGCATGGTATGAACACTTATGTGGTGGCGATTATTCCACTGGCCGTGTTCACCCTC
ACTGGCATCATGGGCAAAGAAGAGCTGAAACAGATCAACTGGGATGTGCTGTGGTTAGTTGCCGGTGGGATCGCGATTGG
TATCGGCCTTGAACAGACGGGACTCGCCCAAGCGTTAGCGCACTCCATCGACTATCAATCTCTCTCACCTATGCTGATTG
TGATTGCTCTTTCGTTGGTGTGCTGGCTAATGGCCAACTTTATGTCTAACACGGCGACTGCCAACTTGATCATGCCGATT
GCCGCTGCGATTGGTACTTCGATGAGTAGCCTTGAGCAAGTCGGCGGCTTACAAGCGCTGTTAGTCGTGGTCGCTTTTTC
CGCGTCACTGGGGATGATTTTGCCCGTTTCGACACCGCCCAACTCGCTTGCTTACTCAACGGGGCTTATCGAAAGCAAAG
ATATGGCAAAAACGGGTTTAGTCATTGGGGGGATTGGGCTTGGCATCGTTTATCTGATGGTGTTCCTACTCGGATAA

Upstream 100 bases:

>100_bases
GAAGCTCGCCACACATCTGCACTGTCACTGATAGCAAAACCCAAAAATTTAACCGCCCTCTAAGACCCATAGATTTCAGT
CGCTTACTCTAAGCTTTCAC

Downstream 100 bases:

>100_bases
ACTCCCTCTTCCTCCCCTCTTTCACAGCTTGTCATCACTCTCGAGATAGCAAGCTGTGAACCTTCTAATCGCACTGAAAT
TGCTTTTGTTTTCCTGATTG

Product: putative transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MSQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLWVLEPVPVFATSILIIALELV
MISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLML
ITSVFSMFMSNTATTVMMLALLGPIVASAPKGDLGIKALVVCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWM
MMGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTTSWHGMNTYVVAIIPLAVFTL
TGIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALAHSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPI
AAAIGTSMSSLEQVGGLQALLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG

Sequences:

>Translated_478_residues
MSQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLWVLEPVPVFATSILIIALELV
MISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLML
ITSVFSMFMSNTATTVMMLALLGPIVASAPKGDLGIKALVVCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWM
MMGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTTSWHGMNTYVVAIIPLAVFTL
TGIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALAHSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPI
AAAIGTSMSSLEQVGGLQALLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG
>Mature_477_residues
SQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLWVLEPVPVFATSILIIALELVM
ISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLMLI
TSVFSMFMSNTATTVMMLALLGPIVASAPKGDLGIKALVVCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMM
MGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTTSWHGMNTYVVAIIPLAVFTLT
GIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALAHSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPIA
AAIGTSMSSLEQVGGLQALLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=538, Percent_Identity=25.2788104089219, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI219802232, Length=462, Percent_Identity=23.8095238095238, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI301069349, Length=302, Percent_Identity=26.158940397351, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI31795546, Length=345, Percent_Identity=24.3478260869565, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI19923838, Length=341, Percent_Identity=24.633431085044, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI31377715, Length=143, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI301069346, Length=143, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI58761541, Length=143, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI301069353, Length=143, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4506979, Length=148, Percent_Identity=31.7567567567568, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI225637549, Length=148, Percent_Identity=31.7567567567568, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI225637552, Length=148, Percent_Identity=31.7567567567568, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786829, Length=498, Percent_Identity=24.0963855421687, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32565804, Length=409, Percent_Identity=28.1173594132029, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71988385, Length=430, Percent_Identity=27.4418604651163, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71989118, Length=459, Percent_Identity=25.2723311546841, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6324340, Length=448, Percent_Identity=31.25, Blast_Score=156, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6322263, Length=415, Percent_Identity=27.2289156626506, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319885, Length=412, Percent_Identity=27.9126213592233, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 51436; Mature: 51305

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VLEPVPVFATSILIIALELVMISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILF
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
MGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLMLITSVFSMFMSNTATTVMMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LLGPIVASAPKGDLGIKALVVCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWM
HHHHHHHCCCCCCCCHHEEHHEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
MMGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTT
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
SWHGMNTYVVAIIPLAVFTLTGIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALA
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHEEEECCCCCEECCCCHHHHHHHHH
HSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPIAAAIGTSMSSLEQVGGLQAL
HHCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCHHHH
LVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG
HHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCHHHHCCEEECHHHHHHHHHHHHHC
>Mature Secondary Structure 
SQEGKPMPQLERGLLVKLLICFLLPLGVLLMPIDAIPIQDLTLVQHRLLAIFLLAALLW
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VLEPVPVFATSILIIALELVMISDKGLHGFRVPDPHHPLGELLKYTDIFSAFSSPIIILF
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
MGGFALAIAASKYELDNNLARVLLKPFGHQPKYIMLGLMLITSVFSMFMSNTATTVMMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LLGPIVASAPKGDLGIKALVVCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWM
HHHHHHHCCCCCCCCHHEEHHEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
MMGLPFVLVQLTIAWFLLQKLFPSSQATMTLKLKGEFQRGWRAMLVYITFALTIVLWMTT
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
SWHGMNTYVVAIIPLAVFTLTGIMGKEELKQINWDVLWLVAGGIAIGIGLEQTGLAQALA
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHEEEECCCCCEECCCCHHHHHHHHH
HSIDYQSLSPMLIVIALSLVCWLMANFMSNTATANLIMPIAAAIGTSMSSLEQVGGLQAL
HHCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCHHHH
LVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKTGLVIGGIGLGIVYLMVFLLG
HHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCHHHHCCEEECHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA