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The map label for this gene is csd1 [H]

Identifier: 147675526

GI number: 147675526

Start: 816151

End: 817401

Strand: Direct

Name: csd1 [H]

Synonym: VC0395_A0805

Alternate gene names: 147675526

Gene position: 816151-817401 (Clockwise)

Preceding gene: 147673493

Following gene: 147674355

Centisome position: 26.99

GC content: 51.4

Gene sequence:

>1251_bases
ATGGCCGCCATGCGCTTCACTCCTGAGTCAGTGCGTCAGCAGTTTCCTGCGCTAGCGCAAATCGTCAATGATAAGCCTGT
GGTGTTTTTCGATGGGCCAGGTGGTTCACAAGTGTCACAATCGGTGCTGGATGCCATGGTGGCTTATTTAGGTCGTTACA
ATGCCAATCTTGGTGGGCACTACTTTTCGAGCCAGAAAACCGTGGAGTTAGTGCAAAGTGCTCGTGAGCATTTGCAAGCG
CTGCTCAATGCCCCCAACCCAGAGTCGATTGTCTTTGGGGCAAACATGACGTCGCTGACTTTCCAGTTTAGCCGTGCGAT
CAGCCGTGATTGGCGAGTGGGCGATGAGGTGATTGTCACCGCATTGGATCACTATTCGAATGTTTCTAGCTGGCAACAAG
CGGCTCAAGACAAAGGCGCAATAGTGCATCAGGCTCGCGTCAATACGGCGGACTGCACCTTAGATCAAGCGCATCTGCTT
TCGTTGATTAATCCACGCACCCGTTTAGTGGCAGTGACTTTTGCTTCCAATACCACGGGATCATTGGTTGAACTTGAATC
TATTATTGAGGCGGCGCATCAGGTCGGGGCGATGGTGTATGTCGATGCGGTGCACTATCTGCCGCATCACCTGCCGGATG
TGCAGGCGCTGGGCTGTGATTTTCTGGCCTGTTCGGCCTATAAATTTTTTGGCCCTCACGTCGGGATTGTGTATGTAGCG
CCGCAGTGGCAAAACACGATTCTGCCTTATAAAGTTGAGCCCGCAACCAATCAAGGGCCGGGACGTTTTGAAACCGGAAC
GCTCAGTTTTGAAGGGCTGGCTGGTGTTATTGCTGCGGTGCAATATTTGGCGCAGTGGGGTGACCCGAGTTCTCGATTAC
GTGAGCGTTTGGTTGAGAGCTATCAGCAATATCAGCAGCATGAACAGCGCCTCAGTGAGTATTTTTTGCAAAAGCTCAGT
GATATGCCAGCGCTGAAACTGCATGGTTTGCAACTGGCAGATGCCGCGAAGCGAACACCGACGTTTGCGTTGACGTGTAC
AGACTGTACACCGCAGTCTATGGCGAAAATGCTCGGCGAACAGAATGTGTGCGTATGGAATGGGCATTTCTATGCACTTG
GGCTGGTTCGTCAATTAGGGCTTGAGTCAAGCGGTGGAGTACTACGCATCGGTCTGATGCACTACAACACCACAGAAGAA
ATTGACCATCTATTTGCTCTTCTACGCGATGGTTTACCACAGCTTGCATAA

Upstream 100 bases:

>100_bases
ATGTTGGCCGATAGCCAACTGTGGCACAACGCTTGCCCGATCCGCACGGTGGATCATCAACAAGAAGGGCATATGGATGT
TTTTGTTTTGACTGCGAAGG

Downstream 100 bases:

>100_bases
GTCGTAAGCCCTTCTAGACATCTTTCACTTCTAGCGATATGCCTTTTCTACTGATATTGACTCAGTGGGAAGGGTATACC
CTTCCTACTTGAAGCTTTAG

Product: aminotransferase, class V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MAAMRFTPESVRQQFPALAQIVNDKPVVFFDGPGGSQVSQSVLDAMVAYLGRYNANLGGHYFSSQKTVELVQSAREHLQA
LLNAPNPESIVFGANMTSLTFQFSRAISRDWRVGDEVIVTALDHYSNVSSWQQAAQDKGAIVHQARVNTADCTLDQAHLL
SLINPRTRLVAVTFASNTTGSLVELESIIEAAHQVGAMVYVDAVHYLPHHLPDVQALGCDFLACSAYKFFGPHVGIVYVA
PQWQNTILPYKVEPATNQGPGRFETGTLSFEGLAGVIAAVQYLAQWGDPSSRLRERLVESYQQYQQHEQRLSEYFLQKLS
DMPALKLHGLQLADAAKRTPTFALTCTDCTPQSMAKMLGEQNVCVWNGHFYALGLVRQLGLESSGGVLRIGLMHYNTTEE
IDHLFALLRDGLPQLA

Sequences:

>Translated_416_residues
MAAMRFTPESVRQQFPALAQIVNDKPVVFFDGPGGSQVSQSVLDAMVAYLGRYNANLGGHYFSSQKTVELVQSAREHLQA
LLNAPNPESIVFGANMTSLTFQFSRAISRDWRVGDEVIVTALDHYSNVSSWQQAAQDKGAIVHQARVNTADCTLDQAHLL
SLINPRTRLVAVTFASNTTGSLVELESIIEAAHQVGAMVYVDAVHYLPHHLPDVQALGCDFLACSAYKFFGPHVGIVYVA
PQWQNTILPYKVEPATNQGPGRFETGTLSFEGLAGVIAAVQYLAQWGDPSSRLRERLVESYQQYQQHEQRLSEYFLQKLS
DMPALKLHGLQLADAAKRTPTFALTCTDCTPQSMAKMLGEQNVCVWNGHFYALGLVRQLGLESSGGVLRIGLMHYNTTEE
IDHLFALLRDGLPQLA
>Mature_415_residues
AAMRFTPESVRQQFPALAQIVNDKPVVFFDGPGGSQVSQSVLDAMVAYLGRYNANLGGHYFSSQKTVELVQSAREHLQAL
LNAPNPESIVFGANMTSLTFQFSRAISRDWRVGDEVIVTALDHYSNVSSWQQAAQDKGAIVHQARVNTADCTLDQAHLLS
LINPRTRLVAVTFASNTTGSLVELESIIEAAHQVGAMVYVDAVHYLPHHLPDVQALGCDFLACSAYKFFGPHVGIVYVAP
QWQNTILPYKVEPATNQGPGRFETGTLSFEGLAGVIAAVQYLAQWGDPSSRLRERLVESYQQYQQHEQRLSEYFLQKLSD
MPALKLHGLQLADAAKRTPTFALTCTDCTPQSMAKMLGEQNVCVWNGHFYALGLVRQLGLESSGGVLRIGLMHYNTTEEI
DHLFALLRDGLPQLA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI156713448, Length=316, Percent_Identity=24.3670886075949, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787970, Length=427, Percent_Identity=29.9765807962529, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789175, Length=413, Percent_Identity=26.8765133171913, Blast_Score=125, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45839; Mature: 45707

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAMRFTPESVRQQFPALAQIVNDKPVVFFDGPGGSQVSQSVLDAMVAYLGRYNANLGGH
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC
YFSSQKTVELVQSAREHLQALLNAPNPESIVFGANMTSLTFQFSRAISRDWRVGDEVIVT
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHH
ALDHYSNVSSWQQAAQDKGAIVHQARVNTADCTLDQAHLLSLINPRTRLVAVTFASNTTG
HHHHHCCHHHHHHHHHCCCCEEEEECCCHHHCCCCHHHHHHHCCCCEEEEEEEEECCCCC
SLVELESIIEAAHQVGAMVYVDAVHYLPHHLPDVQALGCDFLACSAYKFFGPHVGIVYVA
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCEEEEEEC
PQWQNTILPYKVEPATNQGPGRFETGTLSFEGLAGVIAAVQYLAQWGDPSSRLRERLVES
CCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YQQYQQHEQRLSEYFLQKLSDMPALKLHGLQLADAAKRTPTFALTCTDCTPQSMAKMLGE
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHCC
QNVCVWNGHFYALGLVRQLGLESSGGVLRIGLMHYNTTEEIDHLFALLRDGLPQLA
CCEEEECCCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AAMRFTPESVRQQFPALAQIVNDKPVVFFDGPGGSQVSQSVLDAMVAYLGRYNANLGGH
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCC
YFSSQKTVELVQSAREHLQALLNAPNPESIVFGANMTSLTFQFSRAISRDWRVGDEVIVT
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHH
ALDHYSNVSSWQQAAQDKGAIVHQARVNTADCTLDQAHLLSLINPRTRLVAVTFASNTTG
HHHHHCCHHHHHHHHHCCCCEEEEECCCHHHCCCCHHHHHHHCCCCEEEEEEEEECCCCC
SLVELESIIEAAHQVGAMVYVDAVHYLPHHLPDVQALGCDFLACSAYKFFGPHVGIVYVA
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCEEEEEEC
PQWQNTILPYKVEPATNQGPGRFETGTLSFEGLAGVIAAVQYLAQWGDPSSRLRERLVES
CCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YQQYQQHEQRLSEYFLQKLSDMPALKLHGLQLADAAKRTPTFALTCTDCTPQSMAKMLGE
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHCC
QNVCVWNGHFYALGLVRQLGLESSGGVLRIGLMHYNTTEEIDHLFALLRDGLPQLA
CCEEEECCCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]