Click here to switch to the map view.

The map label for this gene is rnd [H]

Identifier: 147675516

GI number: 147675516

Start: 1688963

End: 1690108

Strand: Reverse

Name: rnd [H]

Synonym: VC0395_A1569

Alternate gene names: 147675516

Gene position: 1690108-1688963 (Counterclockwise)

Preceding gene: 147673701

Following gene: 147674907

Centisome position: 55.89

GC content: 50.09

Gene sequence:

>1146_bases
TTGAGCAACAACTGCGAGTTATCTGTGAATTATCAAATTATTAGCCAAGTAGGCGATCTACAACGAGTCTGTCTTGCTGC
CCGTGATGCGGATGTGGTGATGCTGGATACCGAATTTGTCCGTACCCGCACCTTCTTTCCGCAACTGGGGTTGATCCAGA
TGTTTGATGGGGAAAACCTATCGCTGATTGATCCCACCGTGCTGGATGAAATGACGCCGTTTGTCGAGTTATTGCAAGAC
ACTTCGGTATTGAAAGTGCTGCACGCCTGTGGCGAAGATTTGGAAGTGTTCCAGAATGCGTTTGGCTGCACGCCTTTCCC
TATGGTGGATACTCAGATTATGGCCGCGTTTTTGGGCTACGGTTTATCCACTGGGTTTGCGGCGTTAGTGCAAGACCAAC
TGCAAGTTGAGCTAGACAAAAGCGAATCGCGCACCGATTGGTTAGCGCGCCCTCTAAGTGACAAGCAACTGGAATATGCC
GCGGCCGATGTGTTCTATCTGCTACCGATGTACGAAAAACTGGTCGAGCAAGTGACCCAAGCCGGCTGGTGGGACGCGGC
ATTGCAAGAAAGTGAACTGCAAGTGGCCAAGCGCACTAAAGTCAGCAACCCAGAGCTCGCTTACTTAGACATCAAAGGGG
CTTGGCAGCTTAAACCTAAAGAGCTGGCGATCCTCAAACCCCTAGCAACATGGCGTTACCATGAAGCGGTAAATCGAGAT
TTGGCGCTGAACTTCGTGATTAAAGAAACGGACTTACTGACCATTTCGCGTTTGGCACTTCGTAGTCCGAAACGCATGGA
AGAGGAGGGGGTTGATCCGCACGCAATCCGTCGTCACAGCAGCAAAATTATCGCTATGGTGAAAACGGCGCTAGAAACGC
CAGCCGATGCGTATCCACCAGAAATCGTGCCGATCATGGAATACCCAGGTTATAAGCAGTTGTTCAAACGTTTGAAAGAT
GAAGTAAAGAGCGTTTCGAACACCAGTGGCCTTGCGACCGAATTTTTGGCGTCGAAAAAACAGCTTAACCAACTGCTGAG
TTGGGTATGGAAGCGCGACCGCGACCCAGCCCGCTTGCCTGATTTAATGCAAGGGTGGCGTTTACCATTACTTGGCGAGA
AGCTCAATACGCTCGTCTTGAAATAA

Upstream 100 bases:

>100_bases
AAGCAAAGCGCATAAGCTGTACCCAGCTGCGAGTGTTTTTTAATGTTAGAATGCCGGCCTTAGCTGCCGGCATTTTCTTT
CAAAAGAAGTCTCTCTTCTT

Downstream 100 bases:

>100_bases
TCTCCTTCCGACTTGGATCTGCAGCGCCAAGTCGTTTCAGGATAGGTGTTTTATTCACGCATTTTTCTGTCAGTAAAATT
CCATGAACAGTAGGCACTAT

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSNNCELSVNYQIISQVGDLQRVCLAARDADVVMLDTEFVRTRTFFPQLGLIQMFDGENLSLIDPTVLDEMTPFVELLQD
TSVLKVLHACGEDLEVFQNAFGCTPFPMVDTQIMAAFLGYGLSTGFAALVQDQLQVELDKSESRTDWLARPLSDKQLEYA
AADVFYLLPMYEKLVEQVTQAGWWDAALQESELQVAKRTKVSNPELAYLDIKGAWQLKPKELAILKPLATWRYHEAVNRD
LALNFVIKETDLLTISRLALRSPKRMEEEGVDPHAIRRHSSKIIAMVKTALETPADAYPPEIVPIMEYPGYKQLFKRLKD
EVKSVSNTSGLATEFLASKKQLNQLLSWVWKRDRDPARLPDLMQGWRLPLLGEKLNTLVLK

Sequences:

>Translated_381_residues
MSNNCELSVNYQIISQVGDLQRVCLAARDADVVMLDTEFVRTRTFFPQLGLIQMFDGENLSLIDPTVLDEMTPFVELLQD
TSVLKVLHACGEDLEVFQNAFGCTPFPMVDTQIMAAFLGYGLSTGFAALVQDQLQVELDKSESRTDWLARPLSDKQLEYA
AADVFYLLPMYEKLVEQVTQAGWWDAALQESELQVAKRTKVSNPELAYLDIKGAWQLKPKELAILKPLATWRYHEAVNRD
LALNFVIKETDLLTISRLALRSPKRMEEEGVDPHAIRRHSSKIIAMVKTALETPADAYPPEIVPIMEYPGYKQLFKRLKD
EVKSVSNTSGLATEFLASKKQLNQLLSWVWKRDRDPARLPDLMQGWRLPLLGEKLNTLVLK
>Mature_380_residues
SNNCELSVNYQIISQVGDLQRVCLAARDADVVMLDTEFVRTRTFFPQLGLIQMFDGENLSLIDPTVLDEMTPFVELLQDT
SVLKVLHACGEDLEVFQNAFGCTPFPMVDTQIMAAFLGYGLSTGFAALVQDQLQVELDKSESRTDWLARPLSDKQLEYAA
ADVFYLLPMYEKLVEQVTQAGWWDAALQESELQVAKRTKVSNPELAYLDIKGAWQLKPKELAILKPLATWRYHEAVNRDL
ALNFVIKETDLLTISRLALRSPKRMEEEGVDPHAIRRHSSKIIAMVKTALETPADAYPPEIVPIMEYPGYKQLFKRLKDE
VKSVSNTSGLATEFLASKKQLNQLLSWVWKRDRDPARLPDLMQGWRLPLLGEKLNTLVLK

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=371, Percent_Identity=47.4393530997305, Blast_Score=347, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI17531757, Length=228, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI161078302, Length=253, Percent_Identity=26.4822134387352, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 43249; Mature: 43118

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNCELSVNYQIISQVGDLQRVCLAARDADVVMLDTEFVRTRTFFPQLGLIQMFDGENL
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCEEEEECCCCC
SLIDPTVLDEMTPFVELLQDTSVLKVLHACGEDLEVFQNAFGCTPFPMVDTQIMAAFLGY
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GLSTGFAALVQDQLQVELDKSESRTDWLARPLSDKQLEYAAADVFYLLPMYEKLVEQVTQ
CHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGWWDAALQESELQVAKRTKVSNPELAYLDIKGAWQLKPKELAILKPLATWRYHEAVNRD
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHCCC
LALNFVIKETDLLTISRLALRSPKRMEEEGVDPHAIRRHSSKIIAMVKTALETPADAYPP
EEEEEEEECCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EIVPIMEYPGYKQLFKRLKDEVKSVSNTSGLATEFLASKKQLNQLLSWVWKRDRDPARLP
CEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
DLMQGWRLPLLGEKLNTLVLK
HHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SNNCELSVNYQIISQVGDLQRVCLAARDADVVMLDTEFVRTRTFFPQLGLIQMFDGENL
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCEEEEECCCCC
SLIDPTVLDEMTPFVELLQDTSVLKVLHACGEDLEVFQNAFGCTPFPMVDTQIMAAFLGY
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GLSTGFAALVQDQLQVELDKSESRTDWLARPLSDKQLEYAAADVFYLLPMYEKLVEQVTQ
CHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGWWDAALQESELQVAKRTKVSNPELAYLDIKGAWQLKPKELAILKPLATWRYHEAVNRD
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHCCC
LALNFVIKETDLLTISRLALRSPKRMEEEGVDPHAIRRHSSKIIAMVKTALETPADAYPP
EEEEEEEECCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EIVPIMEYPGYKQLFKRLKDEVKSVSNTSGLATEFLASKKQLNQLLSWVWKRDRDPARLP
CEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
DLMQGWRLPLLGEKLNTLVLK
HHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]