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The map label for this gene is torA [H]

Identifier: 147675496

GI number: 147675496

Start: 1377839

End: 1380301

Strand: Reverse

Name: torA [H]

Synonym: VC0395_A1296

Alternate gene names: 147675496

Gene position: 1380301-1377839 (Counterclockwise)

Preceding gene: 147674416

Following gene: 147673686

Centisome position: 45.64

GC content: 51.28

Gene sequence:

>2463_bases
ATGGCGATTACACGAAGAAGTTTTCTGAAAGGTGTCGCAACCACCAGTGCGGCATCGATCATTGGCCCAAGCCTACTGAC
CTCAGTTTCTGCCCAAGCGGCAGAAACCACGGGAACTTGGAAAGTCTCCGGTTCTCACTGGGGCGCATTCCGCGCCCACA
TCTACGGCGGAAAGGTACAAGAGCTGAAAGCGTTGGAGTTGGATACCCACCCAACGGAAATGTTGAACGGCATTCAAGGC
ATTCTGTACAGCCCATCTCGCGTGCGTTACCCAATGGTGCGCCTCGATTGGTTGAAAAAACACAAATACAGTGCAGAAAC
GCGCGGTAACAACCGTTTTATCCGTGTGACTTGGGATGAGGCGATTGACCTATTCTACCGTGAATTAGAGCGTGTGCAGA
AGCAATACGGCCCTTGGGCACTGCACGCAGGCCAAACCGGTTGGAACCAAACCGGTGCTTTCCACAACTGTACCGCGATG
ATGCAACGCGCGGTGGGTATGCACGGTAACTACATCACCAAAGTCGGGGATTACTCGACTGGTGCTGGTCAAACCATCAT
GCCTTACGTACTGGGTTCAACCGAAGTTTACGCGCAAGGTACCTCTTGGAGCGAGATTTTAGACAACTCAGACAACATCA
TTCTGTGGGCAAACGATCCGGTGAAAAACCTGCAAGTGGGTTGGAACTGTGAAACGCACCAGTCTTTCGGCTATCTGGAT
CAACTGAAAGAGAAAGTCGCAAAAGGCGAGATCAACGTGGTTTCTGTTGACCCAGTGAAAAACAAAACGCAGCGTTTCTT
ACAAAACGATCACTTGTACATCAACCCACAAACTGACGTGGCGTTTATGCTGGCGCTCGCGCATGTGTTGTATACCGAAA
ATCTGTACGACAAGAAGTTCATTGAAACTTACTGCTTGGGATTTGAAGAGTTCATCCCTTACGTACTGGGTAAGAGCAAA
GATAAGGTTGAAAAAACGCCTGAGTGGGCAGCGACAATCTGTGGCGTGAAACCCGATGCGATCCGCGATTTCGCCCGTAT
GTTGGTCAATGGTCGTACTCAGCTGCTGTTTGGTTGGTGTATCCAACGTCAAGAGCACGGGGAGCAGCCGTACTGGATGG
GCGCGGTACTGGCGGCCATGATCGGTCAAATCGGTCTGCCGGGTGGCGGTATCTCTTATGGTCACCACTATTCAGGCATC
GGCGTACCTTCAACGGGGTTTGCGGGTCCTGGCGGCTTCCCACGTAACCTTGACCAAGGTGCGAAGCCGAAGTGGGATAA
CAATGACTTCAACGGTTACAGCCGCACGATTCCGGTTGCTCGCTGGATTGATGCGATTCTCGAACCGGGTAAGAAGATCA
ACCACAACGGAAATACAGTCACGCTGCCCGGTTTCAAGATGATGGTGATTTCGGGTTGTAACCCTTGGCACCACCATCAA
GACCGCAACAAAATGAAGCGTGCGTTCCAGAAACTGGAGACTGTGGTGACGATTGATTTCAGTTGGACGGCAACCTGCCG
CTTTTCTGACATCGTACTGCCTGCTTGCACCCAGTGGGAACGTAACGACATCGACTCTTACGGTTCCTACTCAGGTAAAG
GCCTGATTGCGATGCATCGTTTGGTTGACCCGCTGTTCCAGTCACGTACTGACTTTGAAATCATGACCGAGCTGACCCGT
CGCTTTGGCCGTGAAAAAGAGTACACCCGTGGCATGGATGAGATGGAGTGGGTACGTTCACTTTATGACGAGTGTAAGAA
AGCCAACGAAGGTAAATTTGCCATGCCAGAATTCGAAGAGTTCTGGGAAAAAGGCTTCCTTGATTTTGGTACAGGCACAC
CTTGGGTTCGTCATGCGGATTTCCGCAAAGATCCTGAAATCAATGCATTGGGTACGCCTTCTGGTTTTATCGAAATTACG
TCACGTAAGATCGGTCGCTACGGTTATGAACACTGCCAAGAACACCCAATGTGGTTTGAGAAAACCGAACGTTCACACGG
GGGGCCGGGCTCTGACAAATATCCGTTCTGGTTACAATCATGCCACCCAGATAAGCGTCTGCACTCACAAATGTGTGAAG
CCGAAGCATTCCGCGCGACTTACGCAGTGCAGGGGCGTGAGCCAGTGTACATCAACCCAGTGGATGCGAAAGCCAAAGGC
ATTAAAGATGGCGATCTGGTGCGCGTATTCAACGACCGTGGTCAGTTATTGGCGGGAGCGGTGCTGAGTGACAGCTATCC
ACGTGGCGTGATCCGCATTGAAGAGGGGGCTTGGTATGGCCCATTGACAGAGAAAGTTGGGGCGATCTGTACTTACGGCG
ATCCCAATACTCTGACTCTGGATCTGGGAACGTCAGAGCTGGCGCAAGCCACTTCTGCCAATACCTGTATCGTTGATTTT
GAGAAATTCCGTGGTGAAGTACCTCCTGTAACTTCATTCGGTGGCCCAATCGAAGTCATCTAG

Upstream 100 bases:

>100_bases
TCGATACCGACAGTGAAGCGCTGGTACTCAAGTATCTGCAAAAACACTCTTCAGATTTCGCTGAAGGCCATCACTAAGCA
ACGTCATACGGAGTCATAAC

Downstream 100 bases:

>100_bases
TCATCTCTTTAACGTAAAATGCGCGTTATCCCTCAAGCCAGCGTTCAACGCTGGCTTTTTTCTTCTCTTTTATCCGTAAA
TCCGCTTAATCTGTCGCCAA

Product: trimethylamine-N-oxide reductase

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase [H]

Number of amino acids: Translated: 820; Mature: 819

Protein sequence:

>820_residues
MAITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQELKALELDTHPTEMLNGIQG
ILYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDEAIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAM
MQRAVGMHGNYITKVGDYSTGAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLD
QLKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKFIETYCLGFEEFIPYVLGKSK
DKVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWCIQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGI
GVPSTGFAGPGGFPRNLDQGAKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQ
DRNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHRLVDPLFQSRTDFEIMTELTR
RFGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEEFWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEIT
SRKIGRYGYEHCQEHPMWFEKTERSHGGPGSDKYPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPVDAKAKG
IKDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTLDLGTSELAQATSANTCIVDF
EKFRGEVPPVTSFGGPIEVI

Sequences:

>Translated_820_residues
MAITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQELKALELDTHPTEMLNGIQG
ILYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDEAIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAM
MQRAVGMHGNYITKVGDYSTGAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLD
QLKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKFIETYCLGFEEFIPYVLGKSK
DKVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWCIQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGI
GVPSTGFAGPGGFPRNLDQGAKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQ
DRNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHRLVDPLFQSRTDFEIMTELTR
RFGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEEFWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEIT
SRKIGRYGYEHCQEHPMWFEKTERSHGGPGSDKYPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPVDAKAKG
IKDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTLDLGTSELAQATSANTCIVDF
EKFRGEVPPVTSFGGPIEVI
>Mature_819_residues
AITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQELKALELDTHPTEMLNGIQGI
LYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDEAIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAMM
QRAVGMHGNYITKVGDYSTGAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLDQ
LKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKFIETYCLGFEEFIPYVLGKSKD
KVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWCIQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGIG
VPSTGFAGPGGFPRNLDQGAKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQD
RNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHRLVDPLFQSRTDFEIMTELTRR
FGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEEFWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEITS
RKIGRYGYEHCQEHPMWFEKTERSHGGPGSDKYPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPVDAKAKGI
KDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTLDLGTSELAQATSANTCIVDFE
KFRGEVPPVTSFGGPIEVI

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=836, Percent_Identity=52.1531100478469, Blast_Score=884, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=825, Percent_Identity=38.1818181818182, Blast_Score=580, Evalue=1e-166,
Organism=Escherichia coli, GI145693196, Length=786, Percent_Identity=37.9134860050891, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI87081797, Length=869, Percent_Identity=28.078250863061, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI1787870, Length=863, Percent_Identity=27.8099652375435, Blast_Score=256, Evalue=4e-69,
Organism=Escherichia coli, GI171474008, Length=862, Percent_Identity=26.6821345707657, Blast_Score=252, Evalue=8e-68,
Organism=Escherichia coli, GI3868721, Length=706, Percent_Identity=23.5127478753541, Blast_Score=132, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 92318; Mature: 92186

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQ
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCHH
ELKALELDTHPTEMLNGIQGILYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDE
HHEEEECCCCHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
AIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAMMQRAVGMHGNYITKVGDYST
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
GAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLD
CCCCEEEHEEECCCEEEECCCCHHHHHCCCCCEEEEECCCCCCCEECCCCCCCCCCCHHH
QLKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKF
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHH
IETYCLGFEEFIPYVLGKSKDKVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWC
HHHHHCCHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
IQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGIGVPSTGFAGPGGFPRNLDQG
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQ
CCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCEECCCCCEEEECCEEEEEEECCCCHHHCC
DRNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHR
HHHHHHHHHHHHHEEEEEEECEEEEEEECCEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
LVDPLFQSRTDFEIMTELTRRFGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEE
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
FWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEITSRKIGRYGYEHCQEHPMWFE
HHHCCCEECCCCCCCEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHH
KTERSHGGPGSDKYPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPVDAKAKG
HHCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCHHCC
IKDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTL
CCCCCEEEEECCCCCEEEHHHHCCCCCCCEEEECCCCCCCCHHHHHCCEEECCCCCEEEE
DLGTSELAQATSANTCIVDFEKFRGEVPPVTSFGGPIEVI
ECCCHHHHHHCCCCEEEEEHHHHCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
AITRRSFLKGVATTSAASIIGPSLLTSVSAQAAETTGTWKVSGSHWGAFRAHIYGGKVQ
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCHH
ELKALELDTHPTEMLNGIQGILYSPSRVRYPMVRLDWLKKHKYSAETRGNNRFIRVTWDE
HHEEEECCCCHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
AIDLFYRELERVQKQYGPWALHAGQTGWNQTGAFHNCTAMMQRAVGMHGNYITKVGDYST
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
GAGQTIMPYVLGSTEVYAQGTSWSEILDNSDNIILWANDPVKNLQVGWNCETHQSFGYLD
CCCCEEEHEEECCCEEEECCCCHHHHHCCCCCEEEEECCCCCCCEECCCCCCCCCCCHHH
QLKEKVAKGEINVVSVDPVKNKTQRFLQNDHLYINPQTDVAFMLALAHVLYTENLYDKKF
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHH
IETYCLGFEEFIPYVLGKSKDKVEKTPEWAATICGVKPDAIRDFARMLVNGRTQLLFGWC
HHHHHCCHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
IQRQEHGEQPYWMGAVLAAMIGQIGLPGGGISYGHHYSGIGVPSTGFAGPGGFPRNLDQG
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKPKWDNNDFNGYSRTIPVARWIDAILEPGKKINHNGNTVTLPGFKMMVISGCNPWHHHQ
CCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCEECCCCCEEEECCEEEEEEECCCCHHHCC
DRNKMKRAFQKLETVVTIDFSWTATCRFSDIVLPACTQWERNDIDSYGSYSGKGLIAMHR
HHHHHHHHHHHHHEEEEEEECEEEEEEECCEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
LVDPLFQSRTDFEIMTELTRRFGREKEYTRGMDEMEWVRSLYDECKKANEGKFAMPEFEE
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
FWEKGFLDFGTGTPWVRHADFRKDPEINALGTPSGFIEITSRKIGRYGYEHCQEHPMWFE
HHHCCCEECCCCCCCEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHH
KTERSHGGPGSDKYPFWLQSCHPDKRLHSQMCEAEAFRATYAVQGREPVYINPVDAKAKG
HHCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCHHCC
IKDGDLVRVFNDRGQLLAGAVLSDSYPRGVIRIEEGAWYGPLTEKVGAICTYGDPNTLTL
CCCCCEEEEECCCCCEEEHHHHCCCCCCCEEEECCCCCCCCHHHHHCCEEECCCCCEEEE
DLGTSELAQATSANTCIVDFEKFRGEVPPVTSFGGPIEVI
ECCCHHHHHHCCCCEEEEEHHHHCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]