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The map label for this gene is ydfG [C]

Identifier: 147675476

GI number: 147675476

Start: 678393

End: 679118

Strand: Direct

Name: ydfG [C]

Synonym: VC0395_A0637

Alternate gene names: 147675476

Gene position: 678393-679118 (Clockwise)

Preceding gene: 147673637

Following gene: 147674241

Centisome position: 22.43

GC content: 51.1

Gene sequence:

>726_bases
ATGACCGCGGTGTTCATTACCGGTGCGACCTCCGGAATTGGTAAACAACTGGCGTTGGATTATGCCAAACAGGGTTGGCA
AGTGATTGCGTGTGGACGTAATCAGTCGGTGTTAGACAGCTTACATACACAATATGCCAACATTTTTCCCTTGGCGTTTG
ATGTCACCGATCATCCCGGTACAAAAGCGGCATTAGCGCAGCTTCCATGTCAGCCGGAACTCTGGATTTTAAATGCAGGC
GATTGTGAGTACATCGACGATGGCAAGATGGATGTCACACTGATGGCACGTGTGTTCAATATCAATGTGCTTGGCGTAGC
GGCGGTGATTGAAGGTATACAGCCACATTTGTCCTGTGGTCACCGTGTGGCGATTGTTGGCTCGATTGCCAGTGAGCTGG
CCTTGCCGCGAGCAGAAGCTTATGGCGCTTCCAAAGCGGCCGTCGCTTATTTAGCACGAACGCTTCAACTCGATTGGCGT
CCACTTGGTATCGAAGTCACCACCATTTTTCCGGGCTTTGTCGCCACACCACTCACGGATCGCAATACTTTTGCCATGCC
CATGATCATCACAGTAGAGCGTGCCGCCCAGGAGATCAAAGCTGGCTTGGCGCGCGGTGTGTCACAACTCTATTTCCCTA
AACGATTTACTTGGCTGATTCGGTTACTCGGTGCTTTGCCTTATGCATGGCAAGGTCGCTTAGTTCGACGTCTGTTGAAG
GCTTAA

Upstream 100 bases:

>100_bases
TGACCTACCATCGCGATTATTTCGATATGGGGGAAATGCTTTATGAGCAATTGCCTGTGCTTGGGCAAGTTATCCGCGCG
ATTAAGCGGAGACTAGGACA

Downstream 100 bases:

>100_bases
TAAGGATTTTTTGATGAAAATTGCAATCATTGGCTCGGGCATTTCAGGTTTAACCTGTGGTTACTATCTGCACCGTTATC
ACGATATCACCCTATTCGAA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTAVFITGATSGIGKQLALDYAKQGWQVIACGRNQSVLDSLHTQYANIFPLAFDVTDHPGTKAALAQLPCQPELWILNAG
DCEYIDDGKMDVTLMARVFNINVLGVAAVIEGIQPHLSCGHRVAIVGSIASELALPRAEAYGASKAAVAYLARTLQLDWR
PLGIEVTTIFPGFVATPLTDRNTFAMPMIITVERAAQEIKAGLARGVSQLYFPKRFTWLIRLLGALPYAWQGRLVRRLLK
A

Sequences:

>Translated_241_residues
MTAVFITGATSGIGKQLALDYAKQGWQVIACGRNQSVLDSLHTQYANIFPLAFDVTDHPGTKAALAQLPCQPELWILNAG
DCEYIDDGKMDVTLMARVFNINVLGVAAVIEGIQPHLSCGHRVAIVGSIASELALPRAEAYGASKAAVAYLARTLQLDWR
PLGIEVTTIFPGFVATPLTDRNTFAMPMIITVERAAQEIKAGLARGVSQLYFPKRFTWLIRLLGALPYAWQGRLVRRLLK
A
>Mature_240_residues
TAVFITGATSGIGKQLALDYAKQGWQVIACGRNQSVLDSLHTQYANIFPLAFDVTDHPGTKAALAQLPCQPELWILNAGD
CEYIDDGKMDVTLMARVFNINVLGVAAVIEGIQPHLSCGHRVAIVGSIASELALPRAEAYGASKAAVAYLARTLQLDWRP
LGIEVTTIFPGFVATPLTDRNTFAMPMIITVERAAQEIKAGLARGVSQLYFPKRFTWLIRLLGALPYAWQGRLVRRLLKA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=34.020618556701, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=29.4444444444444, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=213, Percent_Identity=28.6384976525822, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=213, Percent_Identity=28.6384976525822, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=208, Percent_Identity=29.3269230769231, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=206, Percent_Identity=29.6116504854369, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=188, Percent_Identity=29.7872340425532, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643142, Length=190, Percent_Identity=30, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26237; Mature: 26106

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVFITGATSGIGKQLALDYAKQGWQVIACGRNQSVLDSLHTQYANIFPLAFDVTDHPG
CEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEEEEEECCCCCC
TKAALAQLPCQPELWILNAGDCEYIDDGKMDVTLMARVFNINVLGVAAVIEGIQPHLSCG
CHHHHHHCCCCCCEEEEECCCCCCCCCCCEEHEEEHHHHHCHHHHHHHHHHCCCHHHCCC
HRVAIVGSIASELALPRAEAYGASKAAVAYLARTLQLDWRPLGIEVTTIFPGFVATPLTD
CEEEEHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCEECCEEEEEECCCHHCCCCCC
RNTFAMPMIITVERAAQEIKAGLARGVSQLYFPKRFTWLIRLLGALPYAWQGRLVRRLLK
CCCEECCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
A
C
>Mature Secondary Structure 
TAVFITGATSGIGKQLALDYAKQGWQVIACGRNQSVLDSLHTQYANIFPLAFDVTDHPG
EEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEEEEEECCCCCC
TKAALAQLPCQPELWILNAGDCEYIDDGKMDVTLMARVFNINVLGVAAVIEGIQPHLSCG
CHHHHHHCCCCCCEEEEECCCCCCCCCCCEEHEEEHHHHHCHHHHHHHHHHCCCHHHCCC
HRVAIVGSIASELALPRAEAYGASKAAVAYLARTLQLDWRPLGIEVTTIFPGFVATPLTD
CEEEEHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCEECCEEEEEECCCHHCCCCCC
RNTFAMPMIITVERAAQEIKAGLARGVSQLYFPKRFTWLIRLLGALPYAWQGRLVRRLLK
CCCEECCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]