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The map label for this gene is lnt [H]

Identifier: 147675422

GI number: 147675422

Start: 512765

End: 514282

Strand: Reverse

Name: lnt [H]

Synonym: VC0395_A0480

Alternate gene names: 147675422

Gene position: 514282-512765 (Counterclockwise)

Preceding gene: 147675736

Following gene: 147673619

Centisome position: 17.01

GC content: 50.59

Gene sequence:

>1518_bases
ATGAACAGCGTATTATCTCATCGCCTAATGCGGCCGCTTACGGCCGCTTTTGTTGGCGTCATAACTCCTCTGGCTTTTGC
CCCGTATCAATTTTGGCCTTTGGCTCTACTCAGCCCATTTATCCTACTGCTTTTGCTCCACCAACAAAGCGCCAAGCGAG
CGGCTTTGATTGCTTATCTCTGGGGGATTGGTCAATTTGCGGTGGGTATCAGTTGGGTACACGTCAGTATTGATACGTTT
GGCGGCATGCCCAAAATTGCCAGCCTGTTTTTAATGACTCTATTGGTCGGCTATCTGGCACTTTATCCAAGCCTTTTCGG
CTGGCTACTCAATCGCTTTTTTCCGAACAACTCACGCAGTAAATGGTTATGTGCTGCCCCAGCTTTGTGGCTGATTACCG
ATTGGCTACGTGGTTGGGTGATGACGGGTTTTCCTTGGCTATGGCTCGGTTACAGTCAAATTGATAGCCCTCTTGCCAAC
TTTGCCCCCGTCGGTGGCGTAGAGCTCATCACTCTGTTACTGCTGTTTTGTGCTGGTAGCTTAGCTTATGCAGTGCTTAA
TCACCGTTGGTTGATGGCTTGCATCCCTCTTGTGGTTTACGCAACGGGTTATGGCCTCCAAGCCATGCAGTGGGTCACCC
CACAAACGGATCGCACAGCCTCACTGGCCTTGATTCAAGGCAATATCGAACAGGGATTGAAATGGCTGCCTAGCCAGCGC
TGGCCAACCATCATGAAATACACCGATCTTACTCGCGAAAACTGGGATGCCGATGTAATCATTTGGCCAGAAGCGGCGAT
CCCCGCTTTTGAATATGAAATCTCCTCATTTCTGCATAATCTTGATGCTGCGGCACGTATGAACCAAAGCGCGGTGATTA
CTGGCATCATCAATCAAAGTGAAGATAAGCAGTACTTCAATAGCGTGCTGACAGTCGGTGATACGCCTCATGGCGAATAC
CGTTATGATCTGACCCTGCGCTACCATAAGTACCACTTGTTGCCTTTTGGCGAATTCGTGCCGTTTGAAGAGATCCTGCG
TCCATTAGCTCCATTCTTTAATTTGCCGATGTCCTCCTTTAGCCAAGGGGCTTACGTGCAACCGAATTTGATTGCAAAGG
GCTTCGCATTTGTCACCGCACTCTGCTACGAAATCATCTTCAATGAGCAAGTACGCGATAATGTGACGCCGGAAACCGAC
TTCCTACTGACGCTTTCGAATGATGCTTGGTTTGGTCGTTCGATAGGCCCATTGCAACACATGGAAATCGCTCGCATGCG
CGCCTTAGAATTGGGCAAGCCGCTGATCCGCGCCACCAACAATGGAGTGACGGCCGTCACTGACGAGCGAGGACGCATCG
TAGCTCAGTTGCCACAATTTGAAACTGGCGTGCTAAAAGCAACGGTCACCCCAACTCGCGGTAGTACACCTTACTTCCTA
TGGGGCACAACGCCACTCTACCTCTGGGTAGGCTTAGCGATTGGGTTCGCTTTCTGGCGCCAGCGCCGGGCTAGATAA

Upstream 100 bases:

>100_bases
GTGGCTCTTCAAGTGACCGTTCCCGATCTGGAAGCCCTTTCGCACGTTGCGGAAGAGTAGTCCCCACTCTCTTACTAAGT
AAGAGTAAAGAAAAGAGACG

Downstream 100 bases:

>100_bases
GTAAAAGTAAAACGGGAAGTTATCTTCCCGTTTTTTATTGCAACGCTTTATCCAACTAAGGTTTCAGTGGTTGGCGGCTA
AACGCTTTACCCCCACATTG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MNSVLSHRLMRPLTAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYLWGIGQFAVGISWVHVSIDTF
GGMPKIASLFLMTLLVGYLALYPSLFGWLLNRFFPNNSRSKWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLAN
FAPVGGVELITLLLLFCAGSLAYAVLNHRWLMACIPLVVYATGYGLQAMQWVTPQTDRTASLALIQGNIEQGLKWLPSQR
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQSEDKQYFNSVLTVGDTPHGEY
RYDLTLRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSFSQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPETD
FLLTLSNDAWFGRSIGPLQHMEIARMRALELGKPLIRATNNGVTAVTDERGRIVAQLPQFETGVLKATVTPTRGSTPYFL
WGTTPLYLWVGLAIGFAFWRQRRAR

Sequences:

>Translated_505_residues
MNSVLSHRLMRPLTAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYLWGIGQFAVGISWVHVSIDTF
GGMPKIASLFLMTLLVGYLALYPSLFGWLLNRFFPNNSRSKWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLAN
FAPVGGVELITLLLLFCAGSLAYAVLNHRWLMACIPLVVYATGYGLQAMQWVTPQTDRTASLALIQGNIEQGLKWLPSQR
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQSEDKQYFNSVLTVGDTPHGEY
RYDLTLRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSFSQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPETD
FLLTLSNDAWFGRSIGPLQHMEIARMRALELGKPLIRATNNGVTAVTDERGRIVAQLPQFETGVLKATVTPTRGSTPYFL
WGTTPLYLWVGLAIGFAFWRQRRAR
>Mature_505_residues
MNSVLSHRLMRPLTAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYLWGIGQFAVGISWVHVSIDTF
GGMPKIASLFLMTLLVGYLALYPSLFGWLLNRFFPNNSRSKWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLAN
FAPVGGVELITLLLLFCAGSLAYAVLNHRWLMACIPLVVYATGYGLQAMQWVTPQTDRTASLALIQGNIEQGLKWLPSQR
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQSEDKQYFNSVLTVGDTPHGEY
RYDLTLRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSFSQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPETD
FLLTLSNDAWFGRSIGPLQHMEIARMRALELGKPLIRATNNGVTAVTDERGRIVAQLPQFETGVLKATVTPTRGSTPYFL
WGTTPLYLWVGLAIGFAFWRQRRAR

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=510, Percent_Identity=47.6470588235294, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57028; Mature: 57028

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVLSHRLMRPLTAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGIGQFAVGISWVHVSIDTFGGMPKIASLFLMTLLVGYLALYPSLFGWLLNRFFPNNSRS
HHHHHHHHEEEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLANFAPVGGVELITLLLLFCAGS
CEEECCHHHHHHHHHHHHHHHCCCHHHEECHHHHCCHHHHCCCCCHHHHHHHHHHHHHHH
LAYAVLNHRWLMACIPLVVYATGYGLQAMQWVTPQTDRTASLALIQGNIEQGLKWLPSQR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEECCHHHHHHHCCCCC
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQS
CCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
EDKQYFNSVLTVGDTPHGEYRYDLTLRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSF
HHHHHHHHHEECCCCCCCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHC
SQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPETDFLLTLSNDAWFGRSIGPLQH
CCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHH
MEIARMRALELGKPLIRATNNGVTAVTDERGRIVAQLPQFETGVLKATVTPTRGSTPYFL
HHHHHHHHHHHCCHHHEECCCCEEEEECCCCCEEEECCCCCCCEEEEEECCCCCCCCEEE
WGTTPLYLWVGLAIGFAFWRQRRAR
ECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSVLSHRLMRPLTAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGIGQFAVGISWVHVSIDTFGGMPKIASLFLMTLLVGYLALYPSLFGWLLNRFFPNNSRS
HHHHHHHHEEEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLANFAPVGGVELITLLLLFCAGS
CEEECCHHHHHHHHHHHHHHHCCCHHHEECHHHHCCHHHHCCCCCHHHHHHHHHHHHHHH
LAYAVLNHRWLMACIPLVVYATGYGLQAMQWVTPQTDRTASLALIQGNIEQGLKWLPSQR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEECCHHHHHHHCCCCC
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQS
CCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
EDKQYFNSVLTVGDTPHGEYRYDLTLRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSF
HHHHHHHHHEECCCCCCCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHC
SQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPETDFLLTLSNDAWFGRSIGPLQH
CCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHH
MEIARMRALELGKPLIRATNNGVTAVTDERGRIVAQLPQFETGVLKATVTPTRGSTPYFL
HHHHHHHHHHHCCHHHEECCCCEEEEECCCCCEEEECCCCCCCEEEEEECCCCCCCCEEE
WGTTPLYLWVGLAIGFAFWRQRRAR
ECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]