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The map label for this gene is cdd

Identifier: 147675337

GI number: 147675337

Start: 863531

End: 864418

Strand: Reverse

Name: cdd

Synonym: VC0395_A0852

Alternate gene names: 147675337

Gene position: 864418-863531 (Counterclockwise)

Preceding gene: 147675623

Following gene: 147674190

Centisome position: 28.58

GC content: 50.23

Gene sequence:

>888_bases
ATGAGAAACCGTATTGAACAAGCATTACAACAAATGCCTGCTTCTTTTGCCCCATATTTACGTGAATTGGTGTTGGCCAA
GGATTTCGATGCCACTTTCTCTGCCGAGCAGTATCAGCAGCTTTTGACCCTTTCGGGTATGGAAGATTCCGATTTGCGCG
TCGCGCTGTTACCTATCGCTGCCGCTTACTCGTATGCCCCCATCTCTGAATTTTATGTCGGTGCGATTGTACGTGGCATC
TCCGGCCGCCTCTATCTGGGCGCCAATATGGAATTTACTGGTGCGCAGCTTGGACAAACCGTACATGCTGAGCAATGCGC
CATTAGCCATGCTTGGATGAAAGGGGAAAAAGGGGTGGCAGACATCACCATCAACTTTAGCCCTTGCGGCCATTGCCGCC
AGTTTATGAATGAGCTGACCACAGCGTCTTCGCTGAAAATTCAACTGCCCAAGCGTGCTGCCAAAACTTTGCAAGAGTAC
CTCCCTGAGTCGTTTGGCCCTGCCGATCTCGGCATTGATTCTGGCCTGATGAGCCCAGTCAATCATGGTAAAACCAGTGA
CGATGATGAAGAGCTGATCCAGCAAGCTCTGCGCGCGATGAACATCAGCCACTCGCCTTATACCCAAAACTTCAGTGGTG
TGGCACTGAAAATGCGCAGTGGCGCGATTTACCTTGGCGCGTATGCCGAAAATGCTGCGTTTAACCCAAGTTTGCCACCG
CTACAAGTTGCCTTAGCACAAGCGATGATGATGGGTGAATCATTCGAGGATATTGAAGCCGCAGCTCTGGTAGAGAGTGC
AACCGGCAAAATCAGCCATCTTGCCGATACTCAAGCAACGCTGGAAGTGATCAATCCCGATATTCCACTTTCTTATCTCT
CACTGTAA

Upstream 100 bases:

>100_bases
GAAACATAAAAATAAATTACACAACTTAACGTGACACTGATCACCTTATAAAATCTCGCATTACCTAAAATAGGATTCCA
TGCAATGAAAAGGAATCACT

Downstream 100 bases:

>100_bases
ACCGAATGAAGAAGCCATTGGCCTCTTCACTTTTTGCTACTAGCTCTCTTAGTCCACCTCTTACTAAAGATGTCGCGCGC
ACACTTTTCCATCACCCACC

Product: cytidine deaminase

Products: NA

Alternate protein names: Cytidine aminohydrolase; CDA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MRNRIEQALQQMPASFAPYLRELVLAKDFDATFSAEQYQQLLTLSGMEDSDLRVALLPIAAAYSYAPISEFYVGAIVRGI
SGRLYLGANMEFTGAQLGQTVHAEQCAISHAWMKGEKGVADITINFSPCGHCRQFMNELTTASSLKIQLPKRAAKTLQEY
LPESFGPADLGIDSGLMSPVNHGKTSDDDEELIQQALRAMNISHSPYTQNFSGVALKMRSGAIYLGAYAENAAFNPSLPP
LQVALAQAMMMGESFEDIEAAALVESATGKISHLADTQATLEVINPDIPLSYLSL

Sequences:

>Translated_295_residues
MRNRIEQALQQMPASFAPYLRELVLAKDFDATFSAEQYQQLLTLSGMEDSDLRVALLPIAAAYSYAPISEFYVGAIVRGI
SGRLYLGANMEFTGAQLGQTVHAEQCAISHAWMKGEKGVADITINFSPCGHCRQFMNELTTASSLKIQLPKRAAKTLQEY
LPESFGPADLGIDSGLMSPVNHGKTSDDDEELIQQALRAMNISHSPYTQNFSGVALKMRSGAIYLGAYAENAAFNPSLPP
LQVALAQAMMMGESFEDIEAAALVESATGKISHLADTQATLEVINPDIPLSYLSL
>Mature_295_residues
MRNRIEQALQQMPASFAPYLRELVLAKDFDATFSAEQYQQLLTLSGMEDSDLRVALLPIAAAYSYAPISEFYVGAIVRGI
SGRLYLGANMEFTGAQLGQTVHAEQCAISHAWMKGEKGVADITINFSPCGHCRQFMNELTTASSLKIQLPKRAAKTLQEY
LPESFGPADLGIDSGLMSPVNHGKTSDDDEELIQQALRAMNISHSPYTQNFSGVALKMRSGAIYLGAYAENAAFNPSLPP
LQVALAQAMMMGESFEDIEAAALVESATGKISHLADTQATLEVINPDIPLSYLSL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Escherichia coli, GI1788465, Length=284, Percent_Identity=48.2394366197183, Blast_Score=245, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDD_VIBC3 (A5F1V7)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F1V7
- SMR:   A5F1V7
- STRING:   A5F1V7
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0852
- eggNOG:   COG0295
- HOGENOM:   HBG591160
- OMA:   NRSHAPY
- ProtClustDB:   PRK09027
- BioCyc:   VCHO345073:VC0395_A0852-MONOMER
- HAMAP:   MF_01558
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013171
- InterPro:   IPR006263
- InterPro:   IPR016193
- InterPro:   IPR020797
- PIRSF:   PIRSF006334
- TIGRFAMs:   TIGR01355

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF08211 dCMP_cyt_deam_2; SSF53927 Cytidine_deaminase-like

EC number: =3.5.4.5

Molecular weight: Translated: 31990; Mature: 31990

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNRIEQALQQMPASFAPYLRELVLAKDFDATFSAEQYQQLLTLSGMEDSDLRVALLPIA
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHH
AAYSYAPISEFYVGAIVRGISGRLYLGANMEFTGAQLGQTVHAEQCAISHAWMKGEKGVA
HHHCCCCHHHHHHHHHHHHCCCCEEECCCCEECHHHHCCHHHHHHHHHHHHHHCCCCCEE
DITINFSPCGHCRQFMNELTTASSLKIQLPKRAAKTLQEYLPESFGPADLGIDSGLMSPV
EEEEECCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
NHGKTSDDDEELIQQALRAMNISHSPYTQNFSGVALKMRSGAIYLGAYAENAAFNPSLPP
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCH
LQVALAQAMMMGESFEDIEAAALVESATGKISHLADTQATLEVINPDIPLSYLSL
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCHHHCC
>Mature Secondary Structure
MRNRIEQALQQMPASFAPYLRELVLAKDFDATFSAEQYQQLLTLSGMEDSDLRVALLPIA
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHH
AAYSYAPISEFYVGAIVRGISGRLYLGANMEFTGAQLGQTVHAEQCAISHAWMKGEKGVA
HHHCCCCHHHHHHHHHHHHCCCCEEECCCCEECHHHHCCHHHHHHHHHHHHHHCCCCCEE
DITINFSPCGHCRQFMNELTTASSLKIQLPKRAAKTLQEYLPESFGPADLGIDSGLMSPV
EEEEECCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
NHGKTSDDDEELIQQALRAMNISHSPYTQNFSGVALKMRSGAIYLGAYAENAAFNPSLPP
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCH
LQVALAQAMMMGESFEDIEAAALVESATGKISHLADTQATLEVINPDIPLSYLSL
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA