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The map label for this gene is gpt

Identifier: 147675317

GI number: 147675317

Start: 1984725

End: 1985189

Strand: Reverse

Name: gpt

Synonym: VC0395_A1867

Alternate gene names: 147675317

Gene position: 1985189-1984725 (Counterclockwise)

Preceding gene: 147675075

Following gene: 147675488

Centisome position: 65.65

GC content: 47.74

Gene sequence:

>465_bases
ATGAGCAAAAAATTCGTTATCACCTGGGACAATATGCAGCATTACTGCCGTGAACTTGCACAGCGTCAAATGCCTGCAGA
ACAATGGAAAGGTATCTTGGGTGTCAGCCGTGGTGGCTTAGTTCCCGCTGCTATTCTCGCTCGCGAGTTGGGCATTCGCT
ATGTGGATACGGTGTGTATCTCGAGCTATGACCATGATCACCAGCGTGATATGACAGTTCTGAAAGCACCAGAGCATGAC
GGCGAAGGTTTCTTGATCATTGACGATCTGGTGGATAGCGGCGATACCGCACGTAAAATCCGTGAAATGTATCCGAAAGC
GAAATTTGTGACTGTCTGTGCTAAACCTGCGGGTAAAGACTTGGTTGACGAGTACGTGGTTGATATTCCACAAGACACTT
GGATCGAGCAACCATGGGACATGGTGCTGTCTTATGTTGAGCCAGTTAATCGCAAGCAAAAATAG

Upstream 100 bases:

>100_bases
GTCTCTCTCAGTGTATGGGTTATGGCGGCCATTTTTGTCATCAAATACATTTTGGCGGCGTAAGAGAAGACATTATAAAA
ATTCAATTTAGGTTTATCAC

Downstream 100 bases:

>100_bases
TCTTTTTGCCGAGAATTTGAAAATGACCCTTTCAAGGGTCATTTTTTTTTACTACTGTTAGCCCAACTTAGCGCAACGCC
AGTAAAGAGACTTGTCATGT

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSKKFVITWDNMQHYCRELAQRQMPAEQWKGILGVSRGGLVPAAILARELGIRYVDTVCISSYDHDHQRDMTVLKAPEHD
GEGFLIIDDLVDSGDTARKIREMYPKAKFVTVCAKPAGKDLVDEYVVDIPQDTWIEQPWDMVLSYVEPVNRKQK

Sequences:

>Translated_154_residues
MSKKFVITWDNMQHYCRELAQRQMPAEQWKGILGVSRGGLVPAAILARELGIRYVDTVCISSYDHDHQRDMTVLKAPEHD
GEGFLIIDDLVDSGDTARKIREMYPKAKFVTVCAKPAGKDLVDEYVVDIPQDTWIEQPWDMVLSYVEPVNRKQK
>Mature_153_residues
SKKFVITWDNMQHYCRELAQRQMPAEQWKGILGVSRGGLVPAAILARELGIRYVDTVCISSYDHDHQRDMTVLKAPEHDG
EGFLIIDDLVDSGDTARKIREMYPKAKFVTVCAKPAGKDLVDEYVVDIPQDTWIEQPWDMVLSYVEPVNRKQK

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily

Homologues:

Organism=Escherichia coli, GI1786433, Length=152, Percent_Identity=69.7368421052632, Blast_Score=231, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XGPT_VIBC3 (A5F5Y8)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F5Y8
- SMR:   A5F5Y8
- STRING:   A5F5Y8
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1867
- eggNOG:   COG0503
- HOGENOM:   HBG503428
- OMA:   LVDTFIT
- ProtClustDB:   PRK09177
- BioCyc:   VCHO345073:VC0395_A1867-MONOMER
- HAMAP:   MF_01903
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 17666; Mature: 17535

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 69-69 BINDING 92-92 BINDING 135-135

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKFVITWDNMQHYCRELAQRQMPAEQWKGILGVSRGGLVPAAILARELGIRYVDTVCI
CCCCEEEEEHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCHHHHHHHHHHCCHHHHHHHH
SSYDHDHQRDMTVLKAPEHDGEGFLIIDDLVDSGDTARKIREMYPKAKFVTVCAKPAGKD
HCCCCCCHHCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHH
LVDEYVVDIPQDTWIEQPWDMVLSYVEPVNRKQK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKKFVITWDNMQHYCRELAQRQMPAEQWKGILGVSRGGLVPAAILARELGIRYVDTVCI
CCCEEEEEHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCHHHHHHHHHHCCHHHHHHHH
SSYDHDHQRDMTVLKAPEHDGEGFLIIDDLVDSGDTARKIREMYPKAKFVTVCAKPAGKD
HCCCCCCHHCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHH
LVDEYVVDIPQDTWIEQPWDMVLSYVEPVNRKQK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA