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The map label for this gene is accA

Identifier: 147674788

GI number: 147674788

Start: 1950061

End: 1951020

Strand: Reverse

Name: accA

Synonym: VC0395_A1835

Alternate gene names: 147674788

Gene position: 1951020-1950061 (Counterclockwise)

Preceding gene: 147675187

Following gene: 147674336

Centisome position: 64.52

GC content: 50.1

Gene sequence:

>960_bases
ATGAGCCTCAATTTTCTTGATTTTGAAAAACCGATTGTCGAACTGGAAACGAAAATTCAGGCGCTGCGTGATGTGTCTCG
TCACAGCACAAGCGCATCCGTAGATCTGGATAAAGAGCTAGAACAGCTTGAGAAGAAGAGCCTTGAGCTGAAAAAGAAGA
TTTTCAGTGACTTAGGTGCATGGCAAGTCGCGCAATTGGCGCGTCATCCGCAACGTCCTTATACGCTGGATTATCTCAAA
CACATCTTTACTGAGTTTGATGAACTGGCGGGCGATCGCGCCTATGCCGATGACAAGGCGATCGTGGGCGGTATTGCACG
CCTTGAAGGTCGTTCGGTCATGGTGATTGGTCACCAAAAAGGTCGTGAAACCCGTGAAAAGGTCAAACGTAACTTTGGTA
TGCCAAAGCCTGAAGGCTACCGCAAAGCGCTGCGTTTGATGGAAATGGCTGAGCGTTTCAATATGCCTATCATCACTTTC
ATTGATACCGCGGGCGCATACCCAGGTGTGGGTGCTGAAGAGCGCGGTCAGTCGGAAGCGATCGCCAAAAACCTTAAAGT
GATGTCAGGCCTGAAGGTGCCAGTCATCTGTAACGTGGTGGGCGAAGGTGGCTCTGGTGGTGCGTTGGCGATTGGTGTCG
GTGACTATGTGAACATGCTGCAATACTCAACCTACTCAGTGATTTCACCAGAAGGTTGTGCGTCGATTCTGTGGCGTGAT
TCTGATAAAGCGCCACAAGCGGCAGAAGCGATGGGTCTGATTGCTCCACGTTTGAAAGAGCTGGAGTTGATTGACGAAAT
CATTGAAGAGCCACTGGGCGGTGCGCATCGTGATCACAAACAGACTGCAGAGAATGTAAAAGCCACGCTACTGCGTCAGT
TGGCCGATCTGGATGCACTGGATCACGAAAACTTGCTGGAGCGCCGCTATCAACGTTTGATGAACTACGGTTACTGTTGA

Upstream 100 bases:

>100_bases
AAAGCAGCTACTTGGTCATGATCAGGTAGAACTCGAATTTAACTAAAATTCAGCCAGTGCGCACTGAGGGTGGCATGGCT
GAGTCACAAAGGATCGATAG

Downstream 100 bases:

>100_bases
TTGCGGTTACTGTTGATTATTTCATCGCGCAGTGGCGGTGGAATATCCACATATAGAAAGGGTTGGCTTAGGTCAGCCCT
TTGGCTTTTCTGGGCTCAAG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSLNFLDFEKPIVELETKIQALRDVSRHSTSASVDLDKELEQLEKKSLELKKKIFSDLGAWQVAQLARHPQRPYTLDYLK
HIFTEFDELAGDRAYADDKAIVGGIARLEGRSVMVIGHQKGRETREKVKRNFGMPKPEGYRKALRLMEMAERFNMPIITF
IDTAGAYPGVGAEERGQSEAIAKNLKVMSGLKVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
SDKAPQAAEAMGLIAPRLKELELIDEIIEEPLGGAHRDHKQTAENVKATLLRQLADLDALDHENLLERRYQRLMNYGYC

Sequences:

>Translated_319_residues
MSLNFLDFEKPIVELETKIQALRDVSRHSTSASVDLDKELEQLEKKSLELKKKIFSDLGAWQVAQLARHPQRPYTLDYLK
HIFTEFDELAGDRAYADDKAIVGGIARLEGRSVMVIGHQKGRETREKVKRNFGMPKPEGYRKALRLMEMAERFNMPIITF
IDTAGAYPGVGAEERGQSEAIAKNLKVMSGLKVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
SDKAPQAAEAMGLIAPRLKELELIDEIIEEPLGGAHRDHKQTAENVKATLLRQLADLDALDHENLLERRYQRLMNYGYC
>Mature_318_residues
SLNFLDFEKPIVELETKIQALRDVSRHSTSASVDLDKELEQLEKKSLELKKKIFSDLGAWQVAQLARHPQRPYTLDYLKH
IFTEFDELAGDRAYADDKAIVGGIARLEGRSVMVIGHQKGRETREKVKRNFGMPKPEGYRKALRLMEMAERFNMPIITFI
DTAGAYPGVGAEERGQSEAIAKNLKVMSGLKVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDS
DKAPQAAEAMGLIAPRLKELELIDEIIEEPLGGAHRDHKQTAENVKATLLRQLADLDALDHENLLERRYQRLMNYGYC

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=319, Percent_Identity=75.5485893416928, Blast_Score=507, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_VIBC3 (A5F624)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F624
- SMR:   A5F624
- STRING:   A5F624
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1835
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   VCHO345073:VC0395_A1835-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35620; Mature: 35489

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNFLDFEKPIVELETKIQALRDVSRHSTSASVDLDKELEQLEKKSLELKKKIFSDLGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
WQVAQLARHPQRPYTLDYLKHIFTEFDELAGDRAYADDKAIVGGIARLEGRSVMVIGHQK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRETREKVKRNFGMPKPEGYRKALRLMEMAERFNMPIITFIDTAGAYPGVGAEERGQSEA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHH
IAKNLKVMSGLKVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
HHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKAPQAAEAMGLIAPRLKELELIDEIIEEPLGGAHRDHKQTAENVKATLLRQLADLDAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DHENLLERRYQRLMNYGYC
CHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLNFLDFEKPIVELETKIQALRDVSRHSTSASVDLDKELEQLEKKSLELKKKIFSDLGA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
WQVAQLARHPQRPYTLDYLKHIFTEFDELAGDRAYADDKAIVGGIARLEGRSVMVIGHQK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRETREKVKRNFGMPKPEGYRKALRLMEMAERFNMPIITFIDTAGAYPGVGAEERGQSEA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHH
IAKNLKVMSGLKVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRD
HHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKAPQAAEAMGLIAPRLKELELIDEIIEEPLGGAHRDHKQTAENVKATLLRQLADLDAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DHENLLERRYQRLMNYGYC
CHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA