Click here to switch to the map view.

The map label for this gene is dnaZX [H]

Identifier: 147674747

GI number: 147674747

Start: 613414

End: 615492

Strand: Direct

Name: dnaZX [H]

Synonym: VC0395_A0572

Alternate gene names: 147674747

Gene position: 613414-615492 (Clockwise)

Preceding gene: 147673655

Following gene: 147675358

Centisome position: 20.28

GC content: 51.71

Gene sequence:

>2079_bases
ATGAGTTATCTTGCTTTAGCACGCAAATGGCGTCCGACACGATTTAGCGAAGTGGTCGGACAATCCCATGTTTTAACCGC
TTTAGAGAACGCTTTGGCGCAAAACCGTTTGCACCATGCGTACTTGTTTAGTGGCACTCGAGGCGTGGGTAAGACCACCA
TAGGTCGTTTGTTTGCGAAGGGGCTCAACTGCGAGACGGGCATAACGGCTACGTCTTGCGGCCAGTGTGCAACCTGTCAA
GAAATTGATCAGGGACGCTTTGTGGATCTGCTCGAGATTGACGCTGCATCACGCACCAAAGTGGAAGATACGCGCGAGCT
ACTCGACAACGTGCAGTACAAACCTGCGCGTGGACGCTTCAAAGTTTACCTGATCGATGAAGTTCATATGCTCTCGCGTC
ACAGCTTCAATGCGCTACTGAAAACGCTTGAAGAGCCGCCTGAGTATGTGAAGTTTTTGCTGGCAACCACTGATCCACAA
AAGCTGCCTGTGACCATCTTGTCGCGCTGTTTGCAGTTCCATCTCAAACCGATCAGTGTAGAAAATATCCAGCAGCAGCT
CGATAAAGTGCTGCACGCCGAACAGATCTCGAGCGACAGCAAAGCACTCAATCTGCTCGCCCATGCTGCGGATGGCAGTA
TGCGCGATGCTCTTAGCTTGACCGATCAAGCGATTGCGTTGGGCAATGGCGTTGTGAAAAGTGACATCGTCGCGCGCATG
CTTGGCACGCTAGACACGGATCATGCCCTGCATCTCTTGCAAGCCATCAGCTTGCAAACGCCACAAGCAGTCATGGATTG
CATCGAAACACTTGCCCCAAATGGCGTAGAGTGGGATGGATTGCTGCAACAGCTTTCGACTCAACTGCATCGAATTGCTA
TGTACCAAGCGCTGCCTGCCACCTTGGATAAATCGCTGCCAGAGGCATCGCGTATTGAGTCGTTGGCCAAAACCTTAGCG
CCGCAAGATGTGCAGCTTTACTACCAAATTGCGCTCAAAGGTCGACAAGATTTACCACTGTCACCCACGGCGCGAATTGG
CATTGAAATGTTGATGCTGCGTATGATGGCGTTTCGTCCATCTCACGTCTCCTTGGCGAGTGTGATTTTGCCACCCAATA
CGGCAGTGACAGCTCCAACAATCGCGGCACCGACTTCTCAAATGGCGACTTCAGCACCGCAACCACAACCCGTTGCGCAG
TCAAACGTATCGCAACCTGCCTCGCAAGCGATACCTTACTCTGTCGCACCGCCAATGATGGCAGCACAGCCTGTGGTAGA
AAGCGCGGTGCCAGTCACTCAGCGAGAAGCATCACACTCGATAAACGCTCCAGAAGTCTCTGTTGTCACCAATACCGACA
CGCAGAGTCAGGCCAGCATGCCAGCCCTAGCAGGGTTGCGTCATCAACTGCGCTCTAAGCGACAAGAAGTACAAAACAAA
GGCGCGGATGGAAAAAAGTCTGACGCGACATCTGCTACTCCAGCGTCGGCGCTAGAGCGTATTGCGCAGAGAGCACAACA
AGTGCAGGTGTCGCCAGAACGCAATGATGAAGATGAGTTGGAGCCCGAAGAGGAAATCTATCAATGGCGTCCGATGCAAC
CTATCGAAGTGGCGGTAAAAAGTGAAGTCACGCCAACGCAACTGAAAAAAGCGTTAGAGCATGAAAAAACGCCGGAAATG
GGAGCGAAGTTGATTGAAGAAGCGGTCGCGCAAGACGCGTGGTCGGCATTGGTTCAACAGCTAGAGACTGCCAAAATGGT
TGAGCAATTGGCGCTGAATTCCGCTTTTGCTCGTCAAGGCGATCAGATTTCTCTAACGCTGCGTCCAAGTCATGCCCATC
TGCACAACGAAAAAGCGCAGCAAGAGTTAGAACAGGCATTGAATCATGTGCTTGGTGAAGCTTGTTCATTAAACATTACC
GTCGGGCAAGAGGGTGAAACACCCCTTGAGCTGCGTGAGCGGCTCTACCAGCAGAAACTCACTTCTGCGCTGCACAGTTT
ACAAACTGATCCAAACGTGCAGTTTATTGAGCGTCGATTTAATGCGCAGCTCGATAGTGACAGCGTACGACCCATTTAA

Upstream 100 bases:

>100_bases
CTTGCCAGAAATTGGTGGTGATAAGCGCCTTGAAGGGTTAGGCTTGCAGGTTTACAGCATCTGTGAATTTGAAGGTCACT
AACCGACAACGGATATTGGA

Downstream 100 bases:

>100_bases
CTGGGGTTGAAACCTAAGTGTCTCACCCCCACACTATGTGAAACATTCAACGATAACCAGAGAGATAAAGATGTTTGGTA
AAGGCGGAATGGGCAACCTG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MSYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAKGLNCETGITATSCGQCATCQ
EIDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQ
KLPVTILSRCLQFHLKPISVENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVARM
LGTLDTDHALHLLQAISLQTPQAVMDCIETLAPNGVEWDGLLQQLSTQLHRIAMYQALPATLDKSLPEASRIESLAKTLA
PQDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRPSHVSLASVILPPNTAVTAPTIAAPTSQMATSAPQPQPVAQ
SNVSQPASQAIPYSVAPPMMAAQPVVESAVPVTQREASHSINAPEVSVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNK
GADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVKSEVTPTQLKKALEHEKTPEM
GAKLIEEAVAQDAWSALVQQLETAKMVEQLALNSAFARQGDQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNIT
VGQEGETPLELRERLYQQKLTSALHSLQTDPNVQFIERRFNAQLDSDSVRPI

Sequences:

>Translated_692_residues
MSYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAKGLNCETGITATSCGQCATCQ
EIDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQ
KLPVTILSRCLQFHLKPISVENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVARM
LGTLDTDHALHLLQAISLQTPQAVMDCIETLAPNGVEWDGLLQQLSTQLHRIAMYQALPATLDKSLPEASRIESLAKTLA
PQDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRPSHVSLASVILPPNTAVTAPTIAAPTSQMATSAPQPQPVAQ
SNVSQPASQAIPYSVAPPMMAAQPVVESAVPVTQREASHSINAPEVSVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNK
GADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVKSEVTPTQLKKALEHEKTPEM
GAKLIEEAVAQDAWSALVQQLETAKMVEQLALNSAFARQGDQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNIT
VGQEGETPLELRERLYQQKLTSALHSLQTDPNVQFIERRFNAQLDSDSVRPI
>Mature_691_residues
SYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAKGLNCETGITATSCGQCATCQE
IDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQK
LPVTILSRCLQFHLKPISVENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVARML
GTLDTDHALHLLQAISLQTPQAVMDCIETLAPNGVEWDGLLQQLSTQLHRIAMYQALPATLDKSLPEASRIESLAKTLAP
QDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRPSHVSLASVILPPNTAVTAPTIAAPTSQMATSAPQPQPVAQS
NVSQPASQAIPYSVAPPMMAAQPVVESAVPVTQREASHSINAPEVSVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNKG
ADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVKSEVTPTQLKKALEHEKTPEMG
AKLIEEAVAQDAWSALVQQLETAKMVEQLALNSAFARQGDQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNITV
GQEGETPLELRERLYQQKLTSALHSLQTDPNVQFIERRFNAQLDSDSVRPI

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=700, Percent_Identity=49.4285714285714, Blast_Score=603, Evalue=1e-173,
Organism=Escherichia coli, GI1787341, Length=146, Percent_Identity=32.1917808219178, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71986063, Length=312, Percent_Identity=21.7948717948718, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324039, Length=223, Percent_Identity=26.0089686098655, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324478, Length=254, Percent_Identity=22.4409448818898, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19921076, Length=318, Percent_Identity=23.8993710691824, Blast_Score=67, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 76029; Mature: 75898

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAK
CCHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHC
GLNCETGITATSCGQCATCQEIDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRF
CCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
KVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQKLPVTILSRCLQFHLKPISV
EEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCH
ENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVARM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGTLDTDHALHLLQAISLQTPQAVMDCIETLAPNGVEWDGLLQQLSTQLHRIAMYQALPA
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TLDKSLPEASRIESLAKTLAPQDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRP
HHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
SHVSLASVILPPNTAVTAPTIAAPTSQMATSAPQPQPVAQSNVSQPASQAIPYSVAPPMM
CCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHCCCCCHHHCCCCCCCCCHH
AAQPVVESAVPVTQREASHSINAPEVSVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNK
HHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHC
GADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVK
CCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHHH
SEVTPTQLKKALEHEKTPEMGAKLIEEAVAQDAWSALVQQLETAKMVEQLALNSAFARQG
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNITVGQEGETPLELRERLYQQKL
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHH
TSALHSLQTDPNVQFIERRFNAQLDSDSVRPI
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAK
CHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHC
GLNCETGITATSCGQCATCQEIDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRF
CCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
KVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQKLPVTILSRCLQFHLKPISV
EEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCH
ENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVARM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGTLDTDHALHLLQAISLQTPQAVMDCIETLAPNGVEWDGLLQQLSTQLHRIAMYQALPA
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TLDKSLPEASRIESLAKTLAPQDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRP
HHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
SHVSLASVILPPNTAVTAPTIAAPTSQMATSAPQPQPVAQSNVSQPASQAIPYSVAPPMM
CCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHCCCCCHHHCCCCCCCCCHH
AAQPVVESAVPVTQREASHSINAPEVSVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNK
HHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHC
GADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVK
CCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHHH
SEVTPTQLKKALEHEKTPEMGAKLIEEAVAQDAWSALVQQLETAKMVEQLALNSAFARQG
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNITVGQEGETPLELRERLYQQKL
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHH
TSALHSLQTDPNVQFIERRFNAQLDSDSVRPI
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]