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The map label for this gene is ndh [H]

Identifier: 147674696

GI number: 147674696

Start: 1591296

End: 1592600

Strand: Reverse

Name: ndh [H]

Synonym: VC0395_A1480

Alternate gene names: 147674696

Gene position: 1592600-1591296 (Counterclockwise)

Preceding gene: 147673914

Following gene: 147675143

Centisome position: 52.66

GC content: 48.89

Gene sequence:

>1305_bases
TTGAGGATTGTTGTTGTGACACGAATTATCGTTGTAGGTGGTGGCGCTGGCGGTTTAGAGCTGGTGACCAAACTGGGTCG
CACACTCGGGCGCAAAGGTCGAGCCAATGTAACCTTGGTGGATCGCAATTCAAGTCATCTCTGGAAACCTTTGTTGCATG
AAGTGGCAACAGGTTCATTGGATGAAGGCGTAGATGCGCTGAGTTACCGCGCACATGCGAAAAATCATAGCTTCGATTTC
CAGCTCGGTAGCTTAGCGTCGATTGATCGTGAAAGTAAAACGATCACGCTCAGTGAACTGAAAGATGAGCATGGTGAGCT
GCTGATGCCAAAGCGTGATTTAGAATACGATATTCTGGTATTAGCGATTGGCTCGACGTCTAATGATTTCAATACTCCGG
GCGTGAAAGAGCACTGTATTTTCCTAGATAGCCCAGAGCAAGCAAACCGTTTCCGTACGGAAATGAACAACGAGTTTTTG
AAGCTGCACGCGAAAAACGGTCAAGGTTCTGTGGATATCGCTATCGTTGGCGCGGGCGCAACAGGTGTTGAGCTATCGGC
TGAATTACATAATGCGGTCAAAGAGTTACGCACTTATGGATTTGGTGACCTCGATTCAAGCAAGCTGAACGTGAACTTGA
TTGAAGCGGGTGAGCGTATTTTGCCAGCACTGCCACCACGCATTTCGGCGGCAGCACACCAAGAGTTGACTAAGTTAGGC
GTCAATGTACGCACGATGACCATGGTGACCAAAGCGGAGAAAGATGGCCTGACGACCAAAGATGGCGAAAAGATTTCTGC
GCACATCATGGTTTGGGCTGCTGGGATCAAAGCACCTGATTTCATGAAAGACATCGCAGGCCTTGAAACGAACCGGATTA
ACCAATTGGTCGTGAAAGGCACACTACAAACCACACGTGATGATGACATCTTTGTCATTGGCGACTTAGCCCAGTGCACA
CAGGCGGATGGCAAATTTGTACCACCTCGCGCACAGGCGGCGCACCAAATGGCTTCACTGGCATTTCGTAATATTGTGGC
CAAAATGTATGGCCGCGAGCTCAAAGCTTACGTTTATAAAGATCATGGCTCACTGGTTTCCCTCAGTCGTTTCTCAACGG
TCGGTAGCCTAATGGGTAACTTAACTCGTGGCTCTATGATGGTCGAAGGGCGTATTGCTCGCGTGGTGTACATCTCTTTA
TACCGTATGCACCAAATGGCGCTGCACGGCATGATTAAAACCGGTTTGATGATGTTGGTGGGGCGTATTAACCGCGTTCT
GCGTCCAAACCTCAAGCTACACTAA

Upstream 100 bases:

>100_bases
CCAAACCTCACCCAAGTCTGCTGGATGTTAAACGCATCATGGCGATAACAGATTCCCTCAGCACGAGCAATCGGGCTGGA
TAATAATTATTCATCTTTAT

Downstream 100 bases:

>100_bases
TCATGTTAGATAGAATCAAGCGGCACTCGTAGCCGCTTGATTTTTATATGTCCCCAAACGAAAGGGGGGCCGTTAGGCGG
TCAGTCAGTGTATGTCTATC

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRIVVVTRIIVVGGGAGGLELVTKLGRTLGRKGRANVTLVDRNSSHLWKPLLHEVATGSLDEGVDALSYRAHAKNHSFDF
QLGSLASIDRESKTITLSELKDEHGELLMPKRDLEYDILVLAIGSTSNDFNTPGVKEHCIFLDSPEQANRFRTEMNNEFL
KLHAKNGQGSVDIAIVGAGATGVELSAELHNAVKELRTYGFGDLDSSKLNVNLIEAGERILPALPPRISAAAHQELTKLG
VNVRTMTMVTKAEKDGLTTKDGEKISAHIMVWAAGIKAPDFMKDIAGLETNRINQLVVKGTLQTTRDDDIFVIGDLAQCT
QADGKFVPPRAQAAHQMASLAFRNIVAKMYGRELKAYVYKDHGSLVSLSRFSTVGSLMGNLTRGSMMVEGRIARVVYISL
YRMHQMALHGMIKTGLMMLVGRINRVLRPNLKLH

Sequences:

>Translated_434_residues
MRIVVVTRIIVVGGGAGGLELVTKLGRTLGRKGRANVTLVDRNSSHLWKPLLHEVATGSLDEGVDALSYRAHAKNHSFDF
QLGSLASIDRESKTITLSELKDEHGELLMPKRDLEYDILVLAIGSTSNDFNTPGVKEHCIFLDSPEQANRFRTEMNNEFL
KLHAKNGQGSVDIAIVGAGATGVELSAELHNAVKELRTYGFGDLDSSKLNVNLIEAGERILPALPPRISAAAHQELTKLG
VNVRTMTMVTKAEKDGLTTKDGEKISAHIMVWAAGIKAPDFMKDIAGLETNRINQLVVKGTLQTTRDDDIFVIGDLAQCT
QADGKFVPPRAQAAHQMASLAFRNIVAKMYGRELKAYVYKDHGSLVSLSRFSTVGSLMGNLTRGSMMVEGRIARVVYISL
YRMHQMALHGMIKTGLMMLVGRINRVLRPNLKLH
>Mature_434_residues
MRIVVVTRIIVVGGGAGGLELVTKLGRTLGRKGRANVTLVDRNSSHLWKPLLHEVATGSLDEGVDALSYRAHAKNHSFDF
QLGSLASIDRESKTITLSELKDEHGELLMPKRDLEYDILVLAIGSTSNDFNTPGVKEHCIFLDSPEQANRFRTEMNNEFL
KLHAKNGQGSVDIAIVGAGATGVELSAELHNAVKELRTYGFGDLDSSKLNVNLIEAGERILPALPPRISAAAHQELTKLG
VNVRTMTMVTKAEKDGLTTKDGEKISAHIMVWAAGIKAPDFMKDIAGLETNRINQLVVKGTLQTTRDDDIFVIGDLAQCT
QADGKFVPPRAQAAHQMASLAFRNIVAKMYGRELKAYVYKDHGSLVSLSRFSTVGSLMGNLTRGSMMVEGRIARVVYISL
YRMHQMALHGMIKTGLMMLVGRINRVLRPNLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=428, Percent_Identity=74.5327102803738, Blast_Score=640, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323794, Length=355, Percent_Identity=29.8591549295775, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323515, Length=445, Percent_Identity=25.3932584269663, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320118, Length=346, Percent_Identity=26.878612716763, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47530; Mature: 47530

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVVVTRIIVVGGGAGGLELVTKLGRTLGRKGRANVTLVDRNSSHLWKPLLHEVATGSL
CEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCH
DEGVDALSYRAHAKNHSFDFQLGSLASIDRESKTITLSELKDEHGELLMPKRDLEYDILV
HCCHHHHHHHHHCCCCCCCEECCCHHHCCCCCCEEEHHHHHCCCCCEECCCCCCCEEEEE
LAIGSTSNDFNTPGVKEHCIFLDSPEQANRFRTEMNNEFLKLHAKNGQGSVDIAIVGAGA
EEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECCC
TGVELSAELHNAVKELRTYGFGDLDSSKLNVNLIEAGERILPALPPRISAAAHQELTKLG
CCCEEHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHC
VNVRTMTMVTKAEKDGLTTKDGEKISAHIMVWAAGIKAPDFMKDIAGLETNRINQLVVKG
CCEEEEEEEEEHHCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCCCCEEEEEE
TLQTTRDDDIFVIGDLAQCTQADGKFVPPRAQAAHQMASLAFRNIVAKMYGRELKAYVYK
ECCCCCCCCEEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
DHGSLVSLSRFSTVGSLMGNLTRGSMMVEGRIARVVYISLYRMHQMALHGMIKTGLMMLV
CCCCEEEHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRINRVLRPNLKLH
HHHHHHHCCCCCCC
>Mature Secondary Structure
MRIVVVTRIIVVGGGAGGLELVTKLGRTLGRKGRANVTLVDRNSSHLWKPLLHEVATGSL
CEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCH
DEGVDALSYRAHAKNHSFDFQLGSLASIDRESKTITLSELKDEHGELLMPKRDLEYDILV
HCCHHHHHHHHHCCCCCCCEECCCHHHCCCCCCEEEHHHHHCCCCCEECCCCCCCEEEEE
LAIGSTSNDFNTPGVKEHCIFLDSPEQANRFRTEMNNEFLKLHAKNGQGSVDIAIVGAGA
EEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECCC
TGVELSAELHNAVKELRTYGFGDLDSSKLNVNLIEAGERILPALPPRISAAAHQELTKLG
CCCEEHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHC
VNVRTMTMVTKAEKDGLTTKDGEKISAHIMVWAAGIKAPDFMKDIAGLETNRINQLVVKG
CCEEEEEEEEEHHCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCCCCEEEEEE
TLQTTRDDDIFVIGDLAQCTQADGKFVPPRAQAAHQMASLAFRNIVAKMYGRELKAYVYK
ECCCCCCCCEEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
DHGSLVSLSRFSTVGSLMGNLTRGSMMVEGRIARVVYISLYRMHQMALHGMIKTGLMMLV
CCCCEEEHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRINRVLRPNLKLH
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]