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The map label for this gene is trpD

Identifier: 147674592

GI number: 147674592

Start: 804170

End: 805168

Strand: Reverse

Name: trpD

Synonym: VC0395_A0794

Alternate gene names: 147674592

Gene position: 805168-804170 (Counterclockwise)

Preceding gene: 147673994

Following gene: 147674842

Centisome position: 26.63

GC content: 52.15

Gene sequence:

>999_bases
ATGCAAACCATTATTAATAAACTCTATGAACAGCAAGGGCTCACGCAAGCCGAGAGCCAACAGCTTTTCGACCAAATTAT
TCGCGGTGAAATGGATCCTGTATTGATGGCGGCGGTACTGACTGCACTGAAAATCAAAGGCGAAACGCCAGATGAAATCG
CGGGTGCGGCTAAAGCCCTGCTCGCCAACGCCAATCCATTTCCGCGTCCTGATTACGACTTTGCCGATATCGTCGGTACC
GGTGGCGATGGCTCAAACACCATCAACATCTCAACCACCGCCGCATTTGTCGCCGCAGCGTGTGGCGTGAAAGTCGCCAA
ACACGGCAACCGTGGGGTATCGAGCAAATCCGGCTCTTCCGATCTGCTCAGCTCATTTGGGATCAACCTTGCCATGAGCG
CGCAAGATTCGCGCCAAGCCTTGGATGATCTCGGTGTCGCTTTCTTGTTTGCCCCTCAGTATCACGGCGGTGTGCGCCAT
GCGATGCCGGTGCGTCAAACCATGAAAACTCGCACCATTTTCAACATCTTAGGCCCCCTGATTAACCCTGCTCGTCCCAA
TATTGAATTGATGGGGGTTTACAGCAAGGATTTGGTTCGTCCTATTGCGCAAACCATGTTACAAATGGGTCTGAAACGCG
CAGCGGTGGTGCATGGTTCAGGTCTTGATGAAGTCGCGATTCATGGCGAAACGCAAGTAGCAGAAATTCGCCAAGGCGAA
TTGATTGAATACACGCTCACTCCGGAAGATTTTGGTGTTAGCCGTTACCCACTGGATGCGATCCGTGGTGGAGAGCCAGA
AGAGAATCGCGCCATCATCACCCAGATCCTAACGGGCAATGGCACAGCAGCACAAATGGCGGCAGTGGCAGTCAACGTTG
CACTTCTGCTGCGTCTATTTGGTCAAGAAGATCTGAAAGCCAACACCCAACAAGCGATCGCCGTGATGAAATCGGGCCAA
GCCTATGGATTGGTTCAGCAGTTAGCACAACGAGGTTAA

Upstream 100 bases:

>100_bases
CCACCCACGGCGCTACCTTGCTGGCCAATGCCATTGATTGGGCATTGTCTTCAACGCCAGCGCAGACTCAATTCGCGTAA
CCGCACAGGGAGAGAATGTT

Downstream 100 bases:

>100_bases
GCAGAATGTCCGAGCAGTTGTCTGAGCATATTTCCGTACAAACCGCGCAAATGGCGCAAGTGCTGGTCAAAATCGTCAAC
GATAAATACCAATGGATTGA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAVLTALKIKGETPDEIAGAAKALLANANPFPRPDYDFADIVGT
GGDGSNTINISTTAAFVAAACGVKVAKHGNRGVSSKSGSSDLLSSFGINLAMSAQDSRQALDDLGVAFLFAPQYHGGVRH
AMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHGSGLDEVAIHGETQVAEIRQGE
LIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTGNGTAAQMAAVAVNVALLLRLFGQEDLKANTQQAIAVMKSGQ
AYGLVQQLAQRG

Sequences:

>Translated_332_residues
MQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAVLTALKIKGETPDEIAGAAKALLANANPFPRPDYDFADIVGT
GGDGSNTINISTTAAFVAAACGVKVAKHGNRGVSSKSGSSDLLSSFGINLAMSAQDSRQALDDLGVAFLFAPQYHGGVRH
AMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHGSGLDEVAIHGETQVAEIRQGE
LIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTGNGTAAQMAAVAVNVALLLRLFGQEDLKANTQQAIAVMKSGQ
AYGLVQQLAQRG
>Mature_332_residues
MQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAVLTALKIKGETPDEIAGAAKALLANANPFPRPDYDFADIVGT
GGDGSNTINISTTAAFVAAACGVKVAKHGNRGVSSKSGSSDLLSSFGINLAMSAQDSRQALDDLGVAFLFAPQYHGGVRH
AMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHGSGLDEVAIHGETQVAEIRQGE
LIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTGNGTAAQMAAVAVNVALLLRLFGQEDLKANTQQAIAVMKSGQ
AYGLVQQLAQRG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=332, Percent_Identity=64.1566265060241, Blast_Score=408, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6320561, Length=314, Percent_Identity=32.1656050955414, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_VIBC3 (A5F210)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F210
- SMR:   A5F210
- STRING:   A5F210
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0794
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   VCHO345073:VC0395_A0794-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35371; Mature: 35371

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAVLTALKIKGETPDEIAGAAKAL
CHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LANANPFPRPDYDFADIVGTGGDGSNTINISTTAAFVAAACGVKVAKHGNRGVSSKSGSS
HHCCCCCCCCCCCHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DLLSSFGINLAMSAQDSRQALDDLGVAFLFAPQYHGGVRHAMPVRQTMKTRTIFNILGPL
HHHHHCCCCEEECCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
INPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHGSGLDEVAIHGETQVAEIRQGE
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCHHHHHHCCCC
LIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTGNGTAAQMAAVAVNVALLLRLF
EEEEEECCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
GQEDLKANTQQAIAVMKSGQAYGLVQQLAQRG
CCHHHCCCHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAVLTALKIKGETPDEIAGAAKAL
CHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LANANPFPRPDYDFADIVGTGGDGSNTINISTTAAFVAAACGVKVAKHGNRGVSSKSGSS
HHCCCCCCCCCCCHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DLLSSFGINLAMSAQDSRQALDDLGVAFLFAPQYHGGVRHAMPVRQTMKTRTIFNILGPL
HHHHHCCCCEEECCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
INPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHGSGLDEVAIHGETQVAEIRQGE
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCHHHHHHCCCC
LIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTGNGTAAQMAAVAVNVALLLRLF
EEEEEECCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
GQEDLKANTQQAIAVMKSGQAYGLVQQLAQRG
CCHHHCCCHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA