Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 147674519

GI number: 147674519

Start: 464791

End: 465849

Strand: Direct

Name: mdtA [H]

Synonym: VC0395_A0438

Alternate gene names: 147674519

Gene position: 464791-465849 (Clockwise)

Preceding gene: 147673664

Following gene: 147674044

Centisome position: 15.37

GC content: 49.29

Gene sequence:

>1059_bases
ATGAACAAAAACACTGTACTTTCATTGACCTTACTGACCCTGCTAATGAACAGCGCTGTGCTATCGGCCAAAGAGCCGAA
CCAGCCGCCCGCGATTTCTGTTGTGACAGAGTCGGTTCAATCTCAGCAAATTTCTCAATCTCTTTCTGTTGTGGGTAAGC
TTAAAGCCGAGCAATCGGTCGACATTGCCGCTGAAGTGGCGGGTAAAGTGGACATGATTGCGGTGCAAGCCAATCAGCAA
GTTAAAAAAGGTCAGATTCTGATCAAATTGGATGATGACAAAGCTCAAGCGGCCTTGGTGGAAGCTAAAGCTTATTTACA
AGATGAGCAGCGTAAACTGACGGAATACGAGCGCTTGCTAAAACGTAATGCGATTACGCCCACGGAAATTGATGCACAGC
GCGCCCGAGTGGAGATTGGTCAAGCGAGATTGAATGCCGCTCAGGCCAATTTGGCCGATTTACACATTACTGCTCCTTTT
GATGGCACGGTTGGGTTTATCGATTTTAGCCGCGGTAAGTGGGTGAGTGCGGGCTCTGAATTACTGACGCTGGATAATCT
TTCCTTGATGCGGCTCGACCTGCAAATTCCAGAACGTTATCTGCCACAGTTAAGCAAGGGCATGAAGGTGCAAGGCAGTA
GCGAAGCGTGGCCAAACGTGCAGTTTGAAGGTTCGGTGGTGGCTGTGGATTCGCGTATCAATCAAGAAACCTTAAATTTA
CGAGTGCGCGTGCATTTCCCCAATCCAGATCAGCGCCTCAAGCCGGGCATGTTGATGTCGGCACGCATCCATTTCCCCGC
TATTAGTGCGCCGATTATTCCTGTGCAGGCCCTTGAGTACTCCGGCACCAAACGTTTTGTTTACGTGATTGGTGAAGACA
ATGTAGCCAAACGACGTGAAGTGAGCCTGGGCGCTCGGGTTGAAAATCAGGTCGTGATTGAGAAAGGCTTACAGATTGGC
GAGAAAATTGTCGTTCAAGGCATAGTCAATATGCGTGACAACGCGCGTGTTAGCGAAGTCACCGTAGAAGGGCGTCCGCT
GAAGAAGGATGACAAATAA

Upstream 100 bases:

>100_bases
GAACCTTACACTTTTACTGGCAATCTTTACGTTCCTTGACGTTTCAGTTGCGTATAACTCGCTACAATATAAACGGATTT
TTTAGACACTAAGCCAAATC

Downstream 100 bases:

>100_bases
TGTGGTTGTCAGATGTATCGGTAAAGCGCCCTGTCGCAGCGTTAGTACTGAGTATGTTGCTGTGCGTGTTTGGTGTGGTC
TCTTTCACTAAACTTGCAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNKNTVLSLTLLTLLMNSAVLSAKEPNQPPAISVVTESVQSQQISQSLSVVGKLKAEQSVDIAAEVAGKVDMIAVQANQQ
VKKGQILIKLDDDKAQAALVEAKAYLQDEQRKLTEYERLLKRNAITPTEIDAQRARVEIGQARLNAAQANLADLHITAPF
DGTVGFIDFSRGKWVSAGSELLTLDNLSLMRLDLQIPERYLPQLSKGMKVQGSSEAWPNVQFEGSVVAVDSRINQETLNL
RVRVHFPNPDQRLKPGMLMSARIHFPAISAPIIPVQALEYSGTKRFVYVIGEDNVAKRREVSLGARVENQVVIEKGLQIG
EKIVVQGIVNMRDNARVSEVTVEGRPLKKDDK

Sequences:

>Translated_352_residues
MNKNTVLSLTLLTLLMNSAVLSAKEPNQPPAISVVTESVQSQQISQSLSVVGKLKAEQSVDIAAEVAGKVDMIAVQANQQ
VKKGQILIKLDDDKAQAALVEAKAYLQDEQRKLTEYERLLKRNAITPTEIDAQRARVEIGQARLNAAQANLADLHITAPF
DGTVGFIDFSRGKWVSAGSELLTLDNLSLMRLDLQIPERYLPQLSKGMKVQGSSEAWPNVQFEGSVVAVDSRINQETLNL
RVRVHFPNPDQRLKPGMLMSARIHFPAISAPIIPVQALEYSGTKRFVYVIGEDNVAKRREVSLGARVENQVVIEKGLQIG
EKIVVQGIVNMRDNARVSEVTVEGRPLKKDDK
>Mature_352_residues
MNKNTVLSLTLLTLLMNSAVLSAKEPNQPPAISVVTESVQSQQISQSLSVVGKLKAEQSVDIAAEVAGKVDMIAVQANQQ
VKKGQILIKLDDDKAQAALVEAKAYLQDEQRKLTEYERLLKRNAITPTEIDAQRARVEIGQARLNAAQANLADLHITAPF
DGTVGFIDFSRGKWVSAGSELLTLDNLSLMRLDLQIPERYLPQLSKGMKVQGSSEAWPNVQFEGSVVAVDSRINQETLNL
RVRVHFPNPDQRLKPGMLMSARIHFPAISAPIIPVQALEYSGTKRFVYVIGEDNVAKRREVSLGARVENQVVIEKGLQIG
EKIVVQGIVNMRDNARVSEVTVEGRPLKKDDK

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=319, Percent_Identity=27.5862068965517, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI87081796, Length=334, Percent_Identity=27.2455089820359, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786668, Length=387, Percent_Identity=25.0645994832041, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789929, Length=357, Percent_Identity=24.3697478991597, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789665, Length=322, Percent_Identity=24.223602484472, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38760; Mature: 38760

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNTVLSLTLLTLLMNSAVLSAKEPNQPPAISVVTESVQSQQISQSLSVVGKLKAEQSV
CCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DIAAEVAGKVDMIAVQANQQVKKGQILIKLDDDKAQAALVEAKAYLQDEQRKLTEYERLL
CHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNAITPTEIDAQRARVEIGQARLNAAQANLADLHITAPFDGTVGFIDFSRGKWVSAGSE
HHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCCEECCCCC
LLTLDNLSLMRLDLQIPERYLPQLSKGMKVQGSSEAWPNVQFEGSVVAVDSRINQETLNL
EEEECCCEEEEEEECCCHHHHHHHHCCCEECCCCCCCCCEEECCCEEEECCCCCCEEEEE
RVRVHFPNPDQRLKPGMLMSARIHFPAISAPIIPVQALEYSGTKRFVYVIGEDNVAKRRE
EEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCCCHHHH
VSLGARVENQVVIEKGLQIGEKIVVQGIVNMRDNARVSEVTVEGRPLKKDDK
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNKNTVLSLTLLTLLMNSAVLSAKEPNQPPAISVVTESVQSQQISQSLSVVGKLKAEQSV
CCCCEEHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DIAAEVAGKVDMIAVQANQQVKKGQILIKLDDDKAQAALVEAKAYLQDEQRKLTEYERLL
CHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNAITPTEIDAQRARVEIGQARLNAAQANLADLHITAPFDGTVGFIDFSRGKWVSAGSE
HHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCCEECCCCC
LLTLDNLSLMRLDLQIPERYLPQLSKGMKVQGSSEAWPNVQFEGSVVAVDSRINQETLNL
EEEECCCEEEEEEECCCHHHHHHHHCCCEECCCCCCCCCEEECCCEEEECCCCCCEEEEE
RVRVHFPNPDQRLKPGMLMSARIHFPAISAPIIPVQALEYSGTKRFVYVIGEDNVAKRRE
EEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCCCHHHH
VSLGARVENQVVIEKGLQIGEKIVVQGIVNMRDNARVSEVTVEGRPLKKDDK
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA