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The map label for this gene is cheA-2 [H]

Identifier: 147674329

GI number: 147674329

Start: 1770717

End: 1773074

Strand: Reverse

Name: cheA-2 [H]

Synonym: VC0395_A1651

Alternate gene names: 147674329

Gene position: 1773074-1770717 (Counterclockwise)

Preceding gene: 147673688

Following gene: 147674819

Centisome position: 58.63

GC content: 48.85

Gene sequence:

>2358_bases
ATGAGCTACGAATTAGACGAAGACATCCTGCAGGACTTTCTGGTAGAAGCCGGCGAAATATTGGAGTTGCTTTCCGAGCA
GCTCGTTGAACTGGAAAACAATCCAGAAGACCGAGATCTGTTGAACGCCATATTCCGTGGTTTTCATACCGTAAAAGGCG
GTGCTGGTTTCTTGGCGTTATCCGAGCTAGTGGAGACCTGCCACGGTGCAGAAAACGTGTTCGACATTTTACGAAATGGT
CAGCGACACGTTTCTCCTAGCTTGATGGATACCATGCTTAAAGCATTGGATACTGTTAATGAACAATTTCGTGCTGTACA
AGAGCGTGAACCACTGCAACCTGCCGACCCTGAATTACTCGATGAATTGCACCGTTTAAGTAAGCCAGCCTCAGAAGACG
AGGATGAGGCTGCAGAAGCGCACTTCGATGAGCCAGAAGAAGAACTGGTTGAAGAGATTATCGAAGAAGTCGTTGAAGAC
GTTGTTGAAGAGGCAGTGCCCAACGTCGAGACGGAGGTTACAGCAAGCGCATCCAGTGGTGTGATTGATAAAGGCTCTAT
TGACGATATCAACGAAGATGAGTTCGAAAAGTTGCTTGATGAACTGCATGGTAAAGGCAAGGCTCCGGGAGCTCAGTCTC
CGCAAGCTCCCGCTTCTGCGCCAGCGAAAGCCGCATCAGTAACCAATTCTGATCTCAACGGTGATATCACGGACGATGAG
TTTGAAAAGCTACTTGATCAACTGCATGGCAAAGGCAAAGGCCCATCGATTGAGACAGCAGCGCCTGCTGCTCCTGTAAC
ACCATCGACGCCTAAAGCGACTGAGACACCGAAACCTGCAGCTGCAAAATCAGCGCCCGGTGGCGATGACTTAATGACCG
ACGAAGAGTTTGAAAAACTACTGGATGAGCTACATGGTTCAGGCAAAGGCCCATCAGTAGAAGAGCTAGAGATGGCTACT
CGTCCAGTGGCGTCTAGCCCTGTTTCTAGTGATGCGAAAGCTTCCGCCGAGGCGAGCGCGCCTTCTACTAAGCCAGCAGC
GAAACCTGTTGCGAAGCCTGCAGCGGCAAAACCTGCTGTGGCTAAAGAGGAACCAGCAAAAGCTCCGGCTCCTGCTGCGG
TGAAGGATTCTGATGAATCTCGCGAAGTGGCCGCTGCTGGTGGTGCTAAGAAAGCACAAACTGAATCTACTGTTCGGGTC
GATACCTCAACACTTGATACCATCATGAACATGGTGGGTGAGTTGGTTCTGGTACGTAACCGACTCTTGAGCCTTGGCCT
GAATAGTAATGACGAAGAGATGTCTAAAGCGGTGGCTAACCTAGATGTGGTTACTGCCGACTTGCAAGGCGCGGTGATGA
AAACGCGTATGCAACCGATCAAAAAAGTGTTCGGGCGTTTCCCTCGCGTGGTTCGTGACTTGGCGCGTAGCTTAAATAAA
GAAATTGACCTTGAGTTACGTGGTGAAGAAACCGATCTCGATAAAAACCTTGTTGAAGCGCTAGCCGATCCTTTGATCCA
CTTGGTGCGTAACTCGGTTGACCATGGTATCGAAATGCCGGACGAGCGTGCTAAAAATGGCAAGTCTCGTACAGGTAAAG
TGATTTTGTCTGCTTCACAAGAGGGAGATCACATACAGTTAGCTATCGTAGATGACGGTGCAGGTATGGATCCCGATAAG
CTGCGTGGTATCGCCGTTAAACGGGGAATAATGGATGAAGATGCCGCGAACCGACTTACCAATAAAGAATGCTTTAACCT
CATTTTTATGCCTGGTTTTTCTAGTAAAGAGAAGATCACCGATATTTCAGGGCGTGGTGTGGGGATGGACGTAGTAAAAA
CCGCTATCAATACACTGAACGGCTCGATCGATATTGACTCTACCATGGGTAAAGGGACAAAGATCACCATCAAAGTGCCT
TTGACTCTGGCTATTCTTCCTACCTTGATGGTTGGCGTCGCGGGGCATCCGTTTGCACTGCCTCTGGCTAGTGTGAATGA
GATTTTCCATCTGGATTTACGTCGTACCAATGTGGTTGATGGTCAGTTGACTATCATAGTGCGCGAAAAATCAATTCCCT
TGTTCTACTTACAAAACTGGTTAGCACCGAAGAAAGGCAAAGTACAGCTTCGCCAAGGTCATGGCCATGTGGTGATTGTA
CAAATCGGCAGTCAGCGCGTAGGTCTGGTTGTGGATACCTTAATTGGTCAAGAAGAAGTGGTGATTAAGCCACTGGATAA
ATTGCTACAGGGCACCCCAGGTATGTCTGGTGCGACTATCACTAGCGATGGTCATATTGCTCTGATTTTGGATGTGCCGG
ATCTGCTCAAGCAGTATGCAGCTGCTTCTCGCGTCTGA

Upstream 100 bases:

>100_bases
AGAGGGGCCGATTCTCAATCCTCATGAACGAATTGATGCTGTCTCATCTCAAGACGAAGTTGACGATCTGTTATCGAGTC
TTGGATTTTAGGGGTAACGT

Downstream 100 bases:

>100_bases
TTAGCTGCACAACGATAAGGATAAACATGGCGATTAAAGTATTAGTTGTTGATGATTCGAGTTTTTTCCGTCGTCGCGTG
AGTGAAATCATCAACTCCGA

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 784

Protein sequence:

>785_residues
MSYELDEDILQDFLVEAGEILELLSEQLVELENNPEDRDLLNAIFRGFHTVKGGAGFLALSELVETCHGAENVFDILRNG
QRHVSPSLMDTMLKALDTVNEQFRAVQEREPLQPADPELLDELHRLSKPASEDEDEAAEAHFDEPEEELVEEIIEEVVED
VVEEAVPNVETEVTASASSGVIDKGSIDDINEDEFEKLLDELHGKGKAPGAQSPQAPASAPAKAASVTNSDLNGDITDDE
FEKLLDQLHGKGKGPSIETAAPAAPVTPSTPKATETPKPAAAKSAPGGDDLMTDEEFEKLLDELHGSGKGPSVEELEMAT
RPVASSPVSSDAKASAEASAPSTKPAAKPVAKPAAAKPAVAKEEPAKAPAPAAVKDSDESREVAAAGGAKKAQTESTVRV
DTSTLDTIMNMVGELVLVRNRLLSLGLNSNDEEMSKAVANLDVVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNK
EIDLELRGEETDLDKNLVEALADPLIHLVRNSVDHGIEMPDERAKNGKSRTGKVILSASQEGDHIQLAIVDDGAGMDPDK
LRGIAVKRGIMDEDAANRLTNKECFNLIFMPGFSSKEKITDISGRGVGMDVVKTAINTLNGSIDIDSTMGKGTKITIKVP
LTLAILPTLMVGVAGHPFALPLASVNEIFHLDLRRTNVVDGQLTIIVREKSIPLFYLQNWLAPKKGKVQLRQGHGHVVIV
QIGSQRVGLVVDTLIGQEEVVIKPLDKLLQGTPGMSGATITSDGHIALILDVPDLLKQYAAASRV

Sequences:

>Translated_785_residues
MSYELDEDILQDFLVEAGEILELLSEQLVELENNPEDRDLLNAIFRGFHTVKGGAGFLALSELVETCHGAENVFDILRNG
QRHVSPSLMDTMLKALDTVNEQFRAVQEREPLQPADPELLDELHRLSKPASEDEDEAAEAHFDEPEEELVEEIIEEVVED
VVEEAVPNVETEVTASASSGVIDKGSIDDINEDEFEKLLDELHGKGKAPGAQSPQAPASAPAKAASVTNSDLNGDITDDE
FEKLLDQLHGKGKGPSIETAAPAAPVTPSTPKATETPKPAAAKSAPGGDDLMTDEEFEKLLDELHGSGKGPSVEELEMAT
RPVASSPVSSDAKASAEASAPSTKPAAKPVAKPAAAKPAVAKEEPAKAPAPAAVKDSDESREVAAAGGAKKAQTESTVRV
DTSTLDTIMNMVGELVLVRNRLLSLGLNSNDEEMSKAVANLDVVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNK
EIDLELRGEETDLDKNLVEALADPLIHLVRNSVDHGIEMPDERAKNGKSRTGKVILSASQEGDHIQLAIVDDGAGMDPDK
LRGIAVKRGIMDEDAANRLTNKECFNLIFMPGFSSKEKITDISGRGVGMDVVKTAINTLNGSIDIDSTMGKGTKITIKVP
LTLAILPTLMVGVAGHPFALPLASVNEIFHLDLRRTNVVDGQLTIIVREKSIPLFYLQNWLAPKKGKVQLRQGHGHVVIV
QIGSQRVGLVVDTLIGQEEVVIKPLDKLLQGTPGMSGATITSDGHIALILDVPDLLKQYAAASRV
>Mature_784_residues
SYELDEDILQDFLVEAGEILELLSEQLVELENNPEDRDLLNAIFRGFHTVKGGAGFLALSELVETCHGAENVFDILRNGQ
RHVSPSLMDTMLKALDTVNEQFRAVQEREPLQPADPELLDELHRLSKPASEDEDEAAEAHFDEPEEELVEEIIEEVVEDV
VEEAVPNVETEVTASASSGVIDKGSIDDINEDEFEKLLDELHGKGKAPGAQSPQAPASAPAKAASVTNSDLNGDITDDEF
EKLLDQLHGKGKGPSIETAAPAAPVTPSTPKATETPKPAAAKSAPGGDDLMTDEEFEKLLDELHGSGKGPSVEELEMATR
PVASSPVSSDAKASAEASAPSTKPAAKPVAKPAAAKPAVAKEEPAKAPAPAAVKDSDESREVAAAGGAKKAQTESTVRVD
TSTLDTIMNMVGELVLVRNRLLSLGLNSNDEEMSKAVANLDVVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKE
IDLELRGEETDLDKNLVEALADPLIHLVRNSVDHGIEMPDERAKNGKSRTGKVILSASQEGDHIQLAIVDDGAGMDPDKL
RGIAVKRGIMDEDAANRLTNKECFNLIFMPGFSSKEKITDISGRGVGMDVVKTAINTLNGSIDIDSTMGKGTKITIKVPL
TLAILPTLMVGVAGHPFALPLASVNEIFHLDLRRTNVVDGQLTIIVREKSIPLFYLQNWLAPKKGKVQLRQGHGHVVIVQ
IGSQRVGLVVDTLIGQEEVVIKPLDKLLQGTPGMSGATITSDGHIALILDVPDLLKQYAAASRV

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=391, Percent_Identity=40.920716112532, Blast_Score=283, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84096; Mature: 83965

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYELDEDILQDFLVEAGEILELLSEQLVELENNPEDRDLLNAIFRGFHTVKGGAGFLAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
SELVETCHGAENVFDILRNGQRHVSPSLMDTMLKALDTVNEQFRAVQEREPLQPADPELL
HHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
DELHRLSKPASEDEDEAAEAHFDEPEEELVEEIIEEVVEDVVEEAVPNVETEVTASASSG
HHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
VIDKGSIDDINEDEFEKLLDELHGKGKAPGAQSPQAPASAPAKAASVTNSDLNGDITDDE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHH
FEKLLDQLHGKGKGPSIETAAPAAPVTPSTPKATETPKPAAAKSAPGGDDLMTDEEFEKL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LDELHGSGKGPSVEELEMATRPVASSPVSSDAKASAEASAPSTKPAAKPVAKPAAAKPAV
HHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKEEPAKAPAPAAVKDSDESREVAAAGGAKKAQTESTVRVDTSTLDTIMNMVGELVLVRN
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
RLLSLGLNSNDEEMSKAVANLDVVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNK
HHHHCCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EIDLELRGEETDLDKNLVEALADPLIHLVRNSVDHGIEMPDERAKNGKSRTGKVILSASQ
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEECC
EGDHIQLAIVDDGAGMDPDKLRGIAVKRGIMDEDAANRLTNKECFNLIFMPGFSSKEKIT
CCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHEEEEECCCCCCCHHC
DISGRGVGMDVVKTAINTLNGSIDIDSTMGKGTKITIKVPLTLAILPTLMVGVAGHPFAL
CCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCC
PLASVNEIFHLDLRRTNVVDGQLTIIVREKSIPLFYLQNWLAPKKGKVQLRQGHGHVVIV
CHHHHHHHHEEECHHCEECCCEEEEEEECCCCCHHHHHHHCCCCCCCEEEEECCCCEEEE
QIGSQRVGLVVDTLIGQEEVVIKPLDKLLQGTPGMSGATITSDGHIALILDVPDLLKQYA
EECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEECCHHHHHHHH
AASRV
HHCCC
>Mature Secondary Structure 
SYELDEDILQDFLVEAGEILELLSEQLVELENNPEDRDLLNAIFRGFHTVKGGAGFLAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
SELVETCHGAENVFDILRNGQRHVSPSLMDTMLKALDTVNEQFRAVQEREPLQPADPELL
HHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
DELHRLSKPASEDEDEAAEAHFDEPEEELVEEIIEEVVEDVVEEAVPNVETEVTASASSG
HHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
VIDKGSIDDINEDEFEKLLDELHGKGKAPGAQSPQAPASAPAKAASVTNSDLNGDITDDE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHH
FEKLLDQLHGKGKGPSIETAAPAAPVTPSTPKATETPKPAAAKSAPGGDDLMTDEEFEKL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LDELHGSGKGPSVEELEMATRPVASSPVSSDAKASAEASAPSTKPAAKPVAKPAAAKPAV
HHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKEEPAKAPAPAAVKDSDESREVAAAGGAKKAQTESTVRVDTSTLDTIMNMVGELVLVRN
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
RLLSLGLNSNDEEMSKAVANLDVVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNK
HHHHCCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EIDLELRGEETDLDKNLVEALADPLIHLVRNSVDHGIEMPDERAKNGKSRTGKVILSASQ
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEECC
EGDHIQLAIVDDGAGMDPDKLRGIAVKRGIMDEDAANRLTNKECFNLIFMPGFSSKEKIT
CCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHEEEEECCCCCCCHHC
DISGRGVGMDVVKTAINTLNGSIDIDSTMGKGTKITIKVPLTLAILPTLMVGVAGHPFAL
CCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCC
PLASVNEIFHLDLRRTNVVDGQLTIIVREKSIPLFYLQNWLAPKKGKVQLRQGHGHVVIV
CHHHHHHHHEEECHHCEECCCEEEEEEECCCCCHHHHHHHCCCCCCCEEEEECCCCEEEE
QIGSQRVGLVVDTLIGQEEVVIKPLDKLLQGTPGMSGATITSDGHIALILDVPDLLKQYA
EECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEECCHHHHHHHH
AASRV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]