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The map label for this gene is gltP [H]

Identifier: 147674225

GI number: 147674225

Start: 799830

End: 800402

Strand: Reverse

Name: gltP [H]

Synonym: VC0395_A0790

Alternate gene names: 147674225

Gene position: 800402-799830 (Counterclockwise)

Preceding gene: 147673648

Following gene: 147674276

Centisome position: 26.47

GC content: 48.34

Gene sequence:

>573_bases
ATGGAAGTGTTAAAGACAAAGGGTTTACTAAACAACATCGGCGTGCAAGTGGTGATCGCCATGCTCGCGGGTACCGCAGT
CGGTGCAGCAATGGGTCACGATGCGACACTATTTGCTCCACTGGGTGCGATTTTTATTAATCTGATCAAAATGCTGGTGA
TTCCTCTGGTGGCTGTGGCACTGATTTCTGATGCAGCAGGTCTGGGTGATAGCCATTCTGCTGGCAAGGTCGGTGCAGTG
ACGTTAAGTTACTTTGCTATTACCTCTGCCGCCGCCGTAGCTCTGGCATTGATCATGGGTGAACTGTTCCAACCGGGTGT
CGGAGTCGATGTTTCTGGTGTAGAGAGCATGTTCTCTTCTGAATACGCTGCGCAAGGTGAGCTCCCCACTTTCTGGGCAA
CCATCATTGGTATGATCCCAACCAACGTTTTCCAGTCACTGAACGAAGCGAACATTCTACAGATCTTGGTTTTCTGTCTG
TTTTTAGGCATTGCGATTTCTAAGCAAGCCAAAGAAAAACGTGACCCAGTGATCAACGCGGTGAACACCATTGATAAGAG
ACTAGAAAAATGA

Upstream 100 bases:

>100_bases
AAACATTCCGTGTAAAAAGTAGGAGCAAAATTTTTGCCCATTTAGTGATATGACACTAGTGGCTAACACTAGGAATTTAC
AATTTATTAGCACAGAGGTT

Downstream 100 bases:

>100_bases
ACAAAAAGAAAGATAGGGATTTGGCGGGAAATTTTGGGATCATTCGGGATCTAAAATAGAGAGAAGATCTAGGAACGGCG
CGGGGTTTGAGGTGGTGAGC

Product: proton/glutamate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MEVLKTKGLLNNIGVQVVIAMLAGTAVGAAMGHDATLFAPLGAIFINLIKMLVIPLVAVALISDAAGLGDSHSAGKVGAV
TLSYFAITSAAAVALALIMGELFQPGVGVDVSGVESMFSSEYAAQGELPTFWATIIGMIPTNVFQSLNEANILQILVFCL
FLGIAISKQAKEKRDPVINAVNTIDKRLEK

Sequences:

>Translated_190_residues
MEVLKTKGLLNNIGVQVVIAMLAGTAVGAAMGHDATLFAPLGAIFINLIKMLVIPLVAVALISDAAGLGDSHSAGKVGAV
TLSYFAITSAAAVALALIMGELFQPGVGVDVSGVESMFSSEYAAQGELPTFWATIIGMIPTNVFQSLNEANILQILVFCL
FLGIAISKQAKEKRDPVINAVNTIDKRLEK
>Mature_190_residues
MEVLKTKGLLNNIGVQVVIAMLAGTAVGAAMGHDATLFAPLGAIFINLIKMLVIPLVAVALISDAAGLGDSHSAGKVGAV
TLSYFAITSAAAVALALIMGELFQPGVGVDVSGVESMFSSEYAAQGELPTFWATIIGMIPTNVFQSLNEANILQILVFCL
FLGIAISKQAKEKRDPVINAVNTIDKRLEK

Specific function: This carrier protein is part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1790514, Length=197, Percent_Identity=29.9492385786802, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789947, Length=185, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 19772; Mature: 19772

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVLKTKGLLNNIGVQVVIAMLAGTAVGAAMGHDATLFAPLGAIFINLIKMLVIPLVAVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LISDAAGLGDSHSAGKVGAVTLSYFAITSAAAVALALIMGELFQPGVGVDVSGVESMFSS
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
EYAAQGELPTFWATIIGMIPTNVFQSLNEANILQILVFCLFLGIAISKQAKEKRDPVINA
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTIDKRLEK
HHHHHHHHCC
>Mature Secondary Structure
MEVLKTKGLLNNIGVQVVIAMLAGTAVGAAMGHDATLFAPLGAIFINLIKMLVIPLVAVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LISDAAGLGDSHSAGKVGAVTLSYFAITSAAAVALALIMGELFQPGVGVDVSGVESMFSS
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
EYAAQGELPTFWATIIGMIPTNVFQSLNEANILQILVFCLFLGIAISKQAKEKRDPVINA
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTIDKRLEK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1971622; 1551855; 8265357; 9278503 [H]