Click here to switch to the map view.

The map label for this gene is srlR [H]

Identifier: 147674087

GI number: 147674087

Start: 34679

End: 35461

Strand: Direct

Name: srlR [H]

Synonym: VC0395_A0038

Alternate gene names: 147674087

Gene position: 34679-35461 (Clockwise)

Preceding gene: 147675027

Following gene: 147675377

Centisome position: 1.15

GC content: 45.21

Gene sequence:

>783_bases
TTGTGTTTTATAATGTCGAAACGAAATACACAACTGAGAAGGCACACAATAGTTAAGCTGGTTAATGAACAAGGTGAGGT
GAGTGTTGAGGCTCTCTCTTCTCAGTTTGAAACATCAGAAGTGACTATTCGCAAAGACTTAGCTTCTCTTGAAAAAAATG
GCCAATTGCTGCGTCGCTATGGTGGTGCTATCGCATTACCGAAAGAAGTGATGCACGATGAATTGAATGAAAAAGTTTCA
GTTCGAAAGATTTCTCTGGCTAAAGCTGCAGCGAAACTAATCCGTGATCATAATCGGATTGTGATTGATAGTGGCAGCAC
CACGGCGGCGTTAATTCAGCAACTGAATGACAAGCGAGGGCTGGTCGTGATGACCAACTCATTGCATGTCGCGAATGCAC
TCAATGAATTAGAAAATGAACCCACACTGCTGATGACTGGCGGTACTTGGGATACCCATTCTGAATCCTTCCAAGGCAAA
GTCGCAGAATCGGTACTGCGCTCTTACGATTTTGACCAGCTGTTTATCGGTGCTGATGGCATCGATCTTGACCGGGGGAC
GACCACGTTCAATGAGCTGGTTGGGCTTAGCAAAGTGATGGCTGAAGTCTCGCGTGAAGTGATCGTGATGATTGAGTCAG
ACAAAGTGGGCCGCAAAATTCCGAACTTAGAGCTGAGCTGGGACAACATTGATGTCTTAGTCACAGATCATGAATTGAGT
GACGAATTTGCCAAACAAATTGAATCTCACCAAGTGCGCGTGATCCGTGCAACCGTGAAATAA

Upstream 100 bases:

>100_bases
TAGGACAAGGTTTTAGCGTGAAATATTAATTTTTTGGATCGAAATAAATGGACTTATTTGTTTCGTTTTAACTATACTTC
GTTTCGATTCGTAACTTTAA

Downstream 100 bases:

>100_bases
AAATCCCTTAGCGCGACTTATTAAGTCAGGGCGCGACAGTATAAAAAATATGGAGTTTAACTATGTGTGGAATTGTTGGT
GCGGTTGCACAACGCGATGT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MCFIMSKRNTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIALPKEVMHDELNEKVS
VRKISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENEPTLLMTGGTWDTHSESFQGK
VAESVLRSYDFDQLFIGADGIDLDRGTTTFNELVGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELS
DEFAKQIESHQVRVIRATVK

Sequences:

>Translated_260_residues
MCFIMSKRNTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIALPKEVMHDELNEKVS
VRKISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENEPTLLMTGGTWDTHSESFQGK
VAESVLRSYDFDQLFIGADGIDLDRGTTTFNELVGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELS
DEFAKQIESHQVRVIRATVK
>Mature_260_residues
MCFIMSKRNTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIALPKEVMHDELNEKVS
VRKISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENEPTLLMTGGTWDTHSESFQGK
VAESVLRSYDFDQLFIGADGIDLDRGTTTFNELVGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELS
DEFAKQIESHQVRVIRATVK

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=246, Percent_Identity=42.6829268292683, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=37.6984126984127, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI226510968, Length=239, Percent_Identity=30.1255230125523, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788069, Length=250, Percent_Identity=28, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787540, Length=207, Percent_Identity=32.3671497584541, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1789829, Length=231, Percent_Identity=29.4372294372294, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790635, Length=256, Percent_Identity=26.5625, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787063, Length=223, Percent_Identity=26.457399103139, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790753, Length=219, Percent_Identity=25.1141552511416, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789170, Length=176, Percent_Identity=29.5454545454545, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082344, Length=210, Percent_Identity=25.7142857142857, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29041; Mature: 29041

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCFIMSKRNTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRY
CEEEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHH
GGAIALPKEVMHDELNEKVSVRKISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRG
CCCEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCC
LVVMTNSLHVANALNELENEPTLLMTGGTWDTHSESFQGKVAESVLRSYDFDQLFIGADG
EEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
IDLDRGTTTFNELVGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELS
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEECCCEEEEEECCHHH
DEFAKQIESHQVRVIRATVK
HHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure
MCFIMSKRNTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRY
CEEEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHH
GGAIALPKEVMHDELNEKVSVRKISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRG
CCCEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCC
LVVMTNSLHVANALNELENEPTLLMTGGTWDTHSESFQGKVAESVLRSYDFDQLFIGADG
EEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
IDLDRGTTTFNELVGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELS
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEECCCEEEEEECCHHH
DEFAKQIESHQVRVIRATVK
HHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]