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The map label for this gene is oadA-1 [H]

Identifier: 147673995

GI number: 147673995

Start: 73431

End: 75224

Strand: Direct

Name: oadA-1 [H]

Synonym: VC0395_A0085

Alternate gene names: 147673995

Gene position: 73431-75224 (Clockwise)

Preceding gene: 147675352

Following gene: 147675475

Centisome position: 2.43

GC content: 50.78

Gene sequence:

>1794_bases
ATGAGCATGTCTAAACCATTAGCCATCACCGATGTCGTCCTACGTGACGCCCACCAATCGCTCTTTGCTACGCGTATGCG
TATTGAAGATATGCTGCCGATCGCGGCTGAGCTGGATAAAATCGGTTACTGGTCGTTGGAAACTTGGGGTGGAGCGACGT
TTGATGCTTGCATCCGTTTCCTTGGCGAAGATCCATGGGAACGTCTACGCGCTTTGAAAAAAGCGATGCCGAATACCCCA
ATGCAGATGTTACTGCGCGGCCAAAACTTACTCGGTTATCGTCATTACGCGGATGATGTCGTCGAGAAATTTGTCGAGCG
CGCCCATGTCAATGGCATGGATGTATTCCGTATTTTTGATGCGATGAACGATGTGCGCAATTTTGAAAAAGCGGTAAAAG
CGACGATTGGTGTGGGCGCTCATGCGCAAGGAACACTCTCTTACACGACGAGCCCTGTGCACAACACGCAAACTTGGGTG
GATTTAGCAAAACGTCTTGAAGATCTCGGCTGCCACTCTTTATGTATCAAAGACATGTCGGGTCTGCTCAAACCTTATGA
GGCCGAAGAGTTAATCACGCGTATTAAGCAGTCTTGCGCGGTGCCTTTGGCGCTGCATTGTCACGCGACAACAGGTTTAT
CTACGGCTACGGCAGTCAAAGCGGTGGAAGCGGGGATTGATATTCTTGATACCGCGATTTCCTCAATGAGCCAGACTTAT
GGCCATACGCCCACGGAAACCGTGGTCGCTATGCTGCAGGATACACCACGTGATACACAACTCAAATTGGAGCAACTTGA
ACCGATCGCGGCTTACTTCCGTGAGGTTCGTAAAAAATACGCCAAGTTTGAAGGTCAGTTAAAAGGTGTTGATTCGCGCA
TTCTGATTGCTCAGGTGCCCGGCGGCATGCTGACCAATATGGAAAGCCAGTTGAAAGAGCAAGGTGCCGCGCACCGTATC
GATGAGGTATTGGAAGAGATCCCTCGCGTTCGTCAGGATCTTGGGTTTATTCCGTTAGTGACTCCTACCTCGCAGATTGT
CGGCACTCAAGCGGTGATCAACGTGTTAACCGGTGAGCGCTATAAGAGCATTACCAAAGAAACCGCAGGCGTTCTTAAAG
GTGAATACGGTGCAACGCCTGCTAGCGTGAATGCTGAGCTGCAAGCACGCGTATTAGAAGGTGGACAAGCGATTACTTGT
CGTCCTGCTGATCTTCTGCAAGATGAACTTGACCATCTCACTAAAGAGCTGCTTGAAAAAGCGCAAGTAGAAAAAATCAC
CTTAGCGGATGCGAAGGTCGATGATGTTCTGACTTATGCGCTGTTTCCACAAGTTGGCCTGAAATTCCTGAAAAATCGCC
ATAATCCAGAGGCGTTTGAACCTGCGCCGGGCAAAGAGCCCGCTCCGGTGGCTACCGCCCCTGCGAGCACCAAACCTGCA
GCAGGTATCGAGAGCTACAGTGTGAAAGTGGACGGCGTGGTGTATGACGTTGAAGTGGGTTCACAAGGTCAATTGACCTC
AGTGGTACCCGCTGGCCAAAAAGCAGCACCAAAACTGGCTGTTGCAACACCCACTCAAGGCGCAGAAGCGGTTGCTGCCC
CTTTGGCGGGGACCATCTTTAAAATCCAAGTTGAACAAGGCGATGAAGTGGCAGAAGGTGATGTGCTTATCGTGTTAGAA
GCGATGAAGATGGAAACTGAAATCCGTGCAGCGCGCAGTGGTGTGATTCAGGAACTGCATGTCAAAGAAGGCGACAGCGT
TCGCGTTGGCGCCTCACTGCTGAGCTTGGCATAA

Upstream 100 bases:

>100_bases
GTTAGTCCACAAGTCGTGGCGGCAATCGCCGCGGCTGTGCATCAGCACCGCAGTGCGACAGCGAAACAGTAGTCTGGATT
ACAAGGATTAAAAGGAGTTA

Downstream 100 bases:

>100_bases
GGGAAAATCATGGACGGATTAATTACCCTATGGCAAGAGACGGGTATTGCCAATTTTGAGCTAGGGCAGATCATCATGAT
CTTGGTCGGCTGTACGCTAC

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MSMSKPLAITDVVLRDAHQSLFATRMRIEDMLPIAAELDKIGYWSLETWGGATFDACIRFLGEDPWERLRALKKAMPNTP
MQMLLRGQNLLGYRHYADDVVEKFVERAHVNGMDVFRIFDAMNDVRNFEKAVKATIGVGAHAQGTLSYTTSPVHNTQTWV
DLAKRLEDLGCHSLCIKDMSGLLKPYEAEELITRIKQSCAVPLALHCHATTGLSTATAVKAVEAGIDILDTAISSMSQTY
GHTPTETVVAMLQDTPRDTQLKLEQLEPIAAYFREVRKKYAKFEGQLKGVDSRILIAQVPGGMLTNMESQLKEQGAAHRI
DEVLEEIPRVRQDLGFIPLVTPTSQIVGTQAVINVLTGERYKSITKETAGVLKGEYGATPASVNAELQARVLEGGQAITC
RPADLLQDELDHLTKELLEKAQVEKITLADAKVDDVLTYALFPQVGLKFLKNRHNPEAFEPAPGKEPAPVATAPASTKPA
AGIESYSVKVDGVVYDVEVGSQGQLTSVVPAGQKAAPKLAVATPTQGAEAVAAPLAGTIFKIQVEQGDEVAEGDVLIVLE
AMKMETEIRAARSGVIQELHVKEGDSVRVGASLLSLA

Sequences:

>Translated_597_residues
MSMSKPLAITDVVLRDAHQSLFATRMRIEDMLPIAAELDKIGYWSLETWGGATFDACIRFLGEDPWERLRALKKAMPNTP
MQMLLRGQNLLGYRHYADDVVEKFVERAHVNGMDVFRIFDAMNDVRNFEKAVKATIGVGAHAQGTLSYTTSPVHNTQTWV
DLAKRLEDLGCHSLCIKDMSGLLKPYEAEELITRIKQSCAVPLALHCHATTGLSTATAVKAVEAGIDILDTAISSMSQTY
GHTPTETVVAMLQDTPRDTQLKLEQLEPIAAYFREVRKKYAKFEGQLKGVDSRILIAQVPGGMLTNMESQLKEQGAAHRI
DEVLEEIPRVRQDLGFIPLVTPTSQIVGTQAVINVLTGERYKSITKETAGVLKGEYGATPASVNAELQARVLEGGQAITC
RPADLLQDELDHLTKELLEKAQVEKITLADAKVDDVLTYALFPQVGLKFLKNRHNPEAFEPAPGKEPAPVATAPASTKPA
AGIESYSVKVDGVVYDVEVGSQGQLTSVVPAGQKAAPKLAVATPTQGAEAVAAPLAGTIFKIQVEQGDEVAEGDVLIVLE
AMKMETEIRAARSGVIQELHVKEGDSVRVGASLLSLA
>Mature_596_residues
SMSKPLAITDVVLRDAHQSLFATRMRIEDMLPIAAELDKIGYWSLETWGGATFDACIRFLGEDPWERLRALKKAMPNTPM
QMLLRGQNLLGYRHYADDVVEKFVERAHVNGMDVFRIFDAMNDVRNFEKAVKATIGVGAHAQGTLSYTTSPVHNTQTWVD
LAKRLEDLGCHSLCIKDMSGLLKPYEAEELITRIKQSCAVPLALHCHATTGLSTATAVKAVEAGIDILDTAISSMSQTYG
HTPTETVVAMLQDTPRDTQLKLEQLEPIAAYFREVRKKYAKFEGQLKGVDSRILIAQVPGGMLTNMESQLKEQGAAHRID
EVLEEIPRVRQDLGFIPLVTPTSQIVGTQAVINVLTGERYKSITKETAGVLKGEYGATPASVNAELQARVLEGGQAITCR
PADLLQDELDHLTKELLEKAQVEKITLADAKVDDVLTYALFPQVGLKFLKNRHNPEAFEPAPGKEPAPVATAPASTKPAA
GIESYSVKVDGVVYDVEVGSQGQLTSVVPAGQKAAPKLAVATPTQGAEAVAAPLAGTIFKIQVEQGDEVAEGDVLIVLEA
MKMETEIRAARSGVIQELHVKEGDSVRVGASLLSLA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=630, Percent_Identity=32.2222222222222, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI106049295, Length=630, Percent_Identity=32.2222222222222, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI106049292, Length=630, Percent_Identity=32.2222222222222, Blast_Score=277, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17562816, Length=624, Percent_Identity=33.0128205128205, Blast_Score=296, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6319695, Length=632, Percent_Identity=31.0126582278481, Blast_Score=283, Evalue=6e-77,
Organism=Saccharomyces cerevisiae, GI6321376, Length=621, Percent_Identity=30.2737520128824, Blast_Score=275, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24652212, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24652210, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24652214, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI19921944, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24652216, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI281363050, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24652224, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24652222, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24652220, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24652218, Length=616, Percent_Identity=35.3896103896104, Blast_Score=317, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 64796; Mature: 64665

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSKPLAITDVVLRDAHQSLFATRMRIEDMLPIAAELDKIGYWSLETWGGATFDACIRF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
LGEDPWERLRALKKAMPNTPMQMLLRGQNLLGYRHYADDVVEKFVERAHVNGMDVFRIFD
HCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AMNDVRNFEKAVKATIGVGAHAQGTLSYTTSPVHNTQTWVDLAKRLEDLGCHSLCIKDMS
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
GLLKPYEAEELITRIKQSCAVPLALHCHATTGLSTATAVKAVEAGIDILDTAISSMSQTY
HHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GHTPTETVVAMLQDTPRDTQLKLEQLEPIAAYFREVRKKYAKFEGQLKGVDSRILIAQVP
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
GGMLTNMESQLKEQGAAHRIDEVLEEIPRVRQDLGFIPLVTPTSQIVGTQAVINVLTGER
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
YKSITKETAGVLKGEYGATPASVNAELQARVLEGGQAITCRPADLLQDELDHLTKELLEK
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHH
AQVEKITLADAKVDDVLTYALFPQVGLKFLKNRHNPEAFEPAPGKEPAPVATAPASTKPA
HHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGIESYSVKVDGVVYDVEVGSQGQLTSVVPAGQKAAPKLAVATPTQGAEAVAAPLAGTIF
CCCCCEEEEECCEEEEEEECCCCCEEEECCCCCCCCCCEEEECCCCCHHHHHHHCCCEEE
KIQVEQGDEVAEGDVLIVLEAMKMETEIRAARSGVIQELHVKEGDSVRVGASLLSLA
EEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCC
>Mature Secondary Structure 
SMSKPLAITDVVLRDAHQSLFATRMRIEDMLPIAAELDKIGYWSLETWGGATFDACIRF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
LGEDPWERLRALKKAMPNTPMQMLLRGQNLLGYRHYADDVVEKFVERAHVNGMDVFRIFD
HCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AMNDVRNFEKAVKATIGVGAHAQGTLSYTTSPVHNTQTWVDLAKRLEDLGCHSLCIKDMS
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
GLLKPYEAEELITRIKQSCAVPLALHCHATTGLSTATAVKAVEAGIDILDTAISSMSQTY
HHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GHTPTETVVAMLQDTPRDTQLKLEQLEPIAAYFREVRKKYAKFEGQLKGVDSRILIAQVP
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
GGMLTNMESQLKEQGAAHRIDEVLEEIPRVRQDLGFIPLVTPTSQIVGTQAVINVLTGER
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
YKSITKETAGVLKGEYGATPASVNAELQARVLEGGQAITCRPADLLQDELDHLTKELLEK
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHH
AQVEKITLADAKVDDVLTYALFPQVGLKFLKNRHNPEAFEPAPGKEPAPVATAPASTKPA
HHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGIESYSVKVDGVVYDVEVGSQGQLTSVVPAGQKAAPKLAVATPTQGAEAVAAPLAGTIF
CCCCCEEEEECCEEEEEEECCCCCEEEECCCCCCCCCCEEEECCCCCHHHHHHHCCCEEE
KIQVEQGDEVAEGDVLIVLEAMKMETEIRAARSGVIQELHVKEGDSVRVGASLLSLA
EEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]