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The map label for this gene is efp

Identifier: 147673907

GI number: 147673907

Start: 2384063

End: 2384629

Strand: Reverse

Name: efp

Synonym: VC0395_A2234

Alternate gene names: 147673907

Gene position: 2384629-2384063 (Counterclockwise)

Preceding gene: 147673873

Following gene: 147673524

Centisome position: 78.85

GC content: 47.44

Gene sequence:

>567_bases
ATGGCTACTGTTAGCACGAATGAATTTAAAGGCGGTCTCAAAATTATGCTTGATAACGAGCCTTGTGTCATTCTCGAAAA
CGAGTATGTAAAACCAGGTAAAGGTCAGGCATTCAACCGCGTGAGAATCCGTAAGCTGCTTACTGGTAAAGTTCTGGAAA
AAACCTTTAAATCGGGTGACACAGCGGAAGTTGCTGATGTTGTCGATATCGATCTGGATTACCTGTACAACGATGGCGAA
TTCTACCACTTCATGAACAACAGCACCTTCGAACAGCTTGCTGCAGATGCAAAAGCGGTTGGCGAGAATGCGAAATGGTT
GGTAGAAAACAACACTTGTATGCTGACGCTGTGGAATGGTAACCCAATCGCGGTCACTCCACCAAACTTCGTTGAGCTAG
AGGTGACTGAAACGGATCCAGGCGTGAAAGGTGACACTCAAGGTACTGGCGGCAAACCAGCGACTCTGTCTACCGGCGCT
GTCGTTCGTGTACCTCTCTTCGTACAGATTGGCGAAGTGATCAAAGTGGACACTCGCTCTGCAGAATACGTTGGCCGTGT
GAAGTAA

Upstream 100 bases:

>100_bases
GCGTTTGCCAGCTGTTGCAACCAGTTTTGCTCAACAGAAATGACTTTTCGGGTTATGATGTGCGGCATTGATTTTAACTC
GAAGATAGTAAGAGGAAAAA

Downstream 100 bases:

>100_bases
TCACCGCGGTCACAAGAAAAAACCAACCTTGCGGTTGGTTTTTTTATGCGTGTAGTTTTAGCCTTGCAATCAAAAAGCTG
GCCTGTTGTCAGCCAGCTTT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MATVSTNEFKGGLKIMLDNEPCVILENEYVKPGKGQAFNRVRIRKLLTGKVLEKTFKSGDTAEVADVVDIDLDYLYNDGE
FYHFMNNSTFEQLAADAKAVGENAKWLVENNTCMLTLWNGNPIAVTPPNFVELEVTETDPGVKGDTQGTGGKPATLSTGA
VVRVPLFVQIGEVIKVDTRSAEYVGRVK

Sequences:

>Translated_188_residues
MATVSTNEFKGGLKIMLDNEPCVILENEYVKPGKGQAFNRVRIRKLLTGKVLEKTFKSGDTAEVADVVDIDLDYLYNDGE
FYHFMNNSTFEQLAADAKAVGENAKWLVENNTCMLTLWNGNPIAVTPPNFVELEVTETDPGVKGDTQGTGGKPATLSTGA
VVRVPLFVQIGEVIKVDTRSAEYVGRVK
>Mature_187_residues
ATVSTNEFKGGLKIMLDNEPCVILENEYVKPGKGQAFNRVRIRKLLTGKVLEKTFKSGDTAEVADVVDIDLDYLYNDGEF
YHFMNNSTFEQLAADAKAVGENAKWLVENNTCMLTLWNGNPIAVTPPNFVELEVTETDPGVKGDTQGTGGKPATLSTGAV
VRVPLFVQIGEVIKVDTRSAEYVGRVK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=73.936170212766, Blast_Score=299, Evalue=7e-83,
Organism=Escherichia coli, GI87082061, Length=184, Percent_Identity=28.804347826087, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_VIBC3 (A5F4X8)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F4X8
- SMR:   A5F4X8
- STRING:   A5F4X8
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2234
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   VCHO345073:VC0395_A2234-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20577; Mature: 20445

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVSTNEFKGGLKIMLDNEPCVILENEYVKPGKGQAFNRVRIRKLLTGKVLEKTFKSGD
CCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
TAEVADVVDIDLDYLYNDGEFYHFMNNSTFEQLAADAKAVGENAKWLVENNTCMLTLWNG
CCCEEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCEEEEEEECC
NPIAVTPPNFVELEVTETDPGVKGDTQGTGGKPATLSTGAVVRVPLFVQIGEVIKVDTRS
CEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEEEEEECCEEEECCCC
AEYVGRVK
CCEEECCC
>Mature Secondary Structure 
ATVSTNEFKGGLKIMLDNEPCVILENEYVKPGKGQAFNRVRIRKLLTGKVLEKTFKSGD
CCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
TAEVADVVDIDLDYLYNDGEFYHFMNNSTFEQLAADAKAVGENAKWLVENNTCMLTLWNG
CCCEEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCEEEEEEECC
NPIAVTPPNFVELEVTETDPGVKGDTQGTGGKPATLSTGAVVRVPLFVQIGEVIKVDTRS
CEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEEEEEEECCEEEECCCC
AEYVGRVK
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA