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The map label for this gene is visC [H]

Identifier: 147673773

GI number: 147673773

Start: 2207776

End: 2209005

Strand: Reverse

Name: visC [H]

Synonym: VC0395_A2051

Alternate gene names: 147673773

Gene position: 2209005-2207776 (Counterclockwise)

Preceding gene: 147673178

Following gene: 147673136

Centisome position: 73.05

GC content: 53.09

Gene sequence:

>1230_bases
ATGATGCAAAGCGTTGATGTTGTAATTATCGGTGGCGGTATGGTCGGCCTAGCGTTAGCGGCGGCTCTAAAAGAGAGTGA
CCTACGCATTGCTGTGGTTGAGAACCAATTACCGGAAGAGGCGCTAAACCCGCTGCCGGATGTGCGCGTTTCTGCCTTGA
GTCGCTCAAGTGAGATTGTGCTGCGTAATCTTAATGCTTGGGCGGGCATTGAAGCGCGCCGCGCTGCGCCCTACATCGCG
ATGGAAGTGTGGGAGCAAGATAGTTTTGCGCGGATTGAATTTAAAGCCAATGAGATGACGCAGCCTAATCTGGGACACAT
TGTTGAAAACCGAGTCATTCAGTTGGCGCTGTTCGAGCAAGTTCAGCAGCAAGCCAATGTGACACTGCATGTGCCTGCGA
CCTGTCAGAGCATCGCCGTGGGTGAAAGCGAAGCATGGCTAACCTTGAGTAATGGCCAAGCCTTGAGCGCAAAATTGGTC
GTAGGGGCCGATGGCGCAAACTCTTGGTTGCGTCGACAAATGGATATTCCTTTGACTCATTGGGATTATGGACACAGTGC
TTTGGTGGCCAATGTGCGTACCAGTGATCCGCACAATAAAGTCGCGCGCCAGATTTTTACTGCCCAAGGACCGTTAGCCT
TTCTCCCCATGTCTGAGCCGCATATGAGTTCGATTGTGTGGTCGACAGAGCCTTCACGCGCTGAAGCTTTGCTCAATATG
AATGATGTGCAGTTTAACAAAGCGCTGACCGCAGAATTCGATGCACGATTAGGCCGCTGTGAAGTAGTGGGCGAGCGGCA
GGCTTTCCCACTTAAGATGCGTTATGCCCGTGATTTTGTTGCGCCTCGGGTTGCTCTCGTCGGGGATGCCGCGCACACCA
TTCATCCGCTGGCTGGGCAGGGAGTGAACTTAGGTTTACTGGATGCTGCCTGTTTGGCACAAGAGCTGCTGAGCTTATGG
CAGCAAAATCGCGACATTGGTGATGAGCGTAATTTGCGCCATTATGAGCGCTGGCGGAAAGCGGAAGCTGCCAAAATGAT
TGCGGCGATGCAAGGTTTCCGCGATCTGTTTGAGGGGGATAACCCTGCTAAGAAACTGATCCGTGGGATCGGCATGCGTC
TGGTTGGTCAATTGCCGGGTGCCAAAGATGAAATCATGAAACGCGCACTAGGCCTGAAGGGCGATCTGCCTGAGCTGGCG
AAGCAGGTTTGGTTAGAGCGTGCCTACTGA

Upstream 100 bases:

>100_bases
GGCGTAACCTTGGTCTAATGGCGATGGATAATTTGCCGTTATTGAAAGCTCCGTTATTGCGCCGCACTCTCGGCATAGTG
AACCGTTAATAGGTAAAAGA

Downstream 100 bases:

>100_bases
TTGAATAAAAAGTTCAACAAATAAAAAGGGTTGGCAGTGCCAACCATTTTTACATTAAATCGCTTTATATTAAATCGAAT
GCTATTGAGTGTTTGCTTGT

Product: 2-octaprenyl-6-methoxyphenol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MMQSVDVVIIGGGMVGLALAAALKESDLRIAVVENQLPEEALNPLPDVRVSALSRSSEIVLRNLNAWAGIEARRAAPYIA
MEVWEQDSFARIEFKANEMTQPNLGHIVENRVIQLALFEQVQQQANVTLHVPATCQSIAVGESEAWLTLSNGQALSAKLV
VGADGANSWLRRQMDIPLTHWDYGHSALVANVRTSDPHNKVARQIFTAQGPLAFLPMSEPHMSSIVWSTEPSRAEALLNM
NDVQFNKALTAEFDARLGRCEVVGERQAFPLKMRYARDFVAPRVALVGDAAHTIHPLAGQGVNLGLLDAACLAQELLSLW
QQNRDIGDERNLRHYERWRKAEAAKMIAAMQGFRDLFEGDNPAKKLIRGIGMRLVGQLPGAKDEIMKRALGLKGDLPELA
KQVWLERAY

Sequences:

>Translated_409_residues
MMQSVDVVIIGGGMVGLALAAALKESDLRIAVVENQLPEEALNPLPDVRVSALSRSSEIVLRNLNAWAGIEARRAAPYIA
MEVWEQDSFARIEFKANEMTQPNLGHIVENRVIQLALFEQVQQQANVTLHVPATCQSIAVGESEAWLTLSNGQALSAKLV
VGADGANSWLRRQMDIPLTHWDYGHSALVANVRTSDPHNKVARQIFTAQGPLAFLPMSEPHMSSIVWSTEPSRAEALLNM
NDVQFNKALTAEFDARLGRCEVVGERQAFPLKMRYARDFVAPRVALVGDAAHTIHPLAGQGVNLGLLDAACLAQELLSLW
QQNRDIGDERNLRHYERWRKAEAAKMIAAMQGFRDLFEGDNPAKKLIRGIGMRLVGQLPGAKDEIMKRALGLKGDLPELA
KQVWLERAY
>Mature_409_residues
MMQSVDVVIIGGGMVGLALAAALKESDLRIAVVENQLPEEALNPLPDVRVSALSRSSEIVLRNLNAWAGIEARRAAPYIA
MEVWEQDSFARIEFKANEMTQPNLGHIVENRVIQLALFEQVQQQANVTLHVPATCQSIAVGESEAWLTLSNGQALSAKLV
VGADGANSWLRRQMDIPLTHWDYGHSALVANVRTSDPHNKVARQIFTAQGPLAFLPMSEPHMSSIVWSTEPSRAEALLNM
NDVQFNKALTAEFDARLGRCEVVGERQAFPLKMRYARDFVAPRVALVGDAAHTIHPLAGQGVNLGLLDAACLAQELLSLW
QQNRDIGDERNLRHYERWRKAEAAKMIAAMQGFRDLFEGDNPAKKLIRGIGMRLVGQLPGAKDEIMKRALGLKGDLPELA
KQVWLERAY

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=424, Percent_Identity=30.6603773584906, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI32967307, Length=371, Percent_Identity=32.3450134770889, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1789273, Length=398, Percent_Identity=56.0301507537689, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1786883, Length=391, Percent_Identity=36.8286445012788, Blast_Score=237, Evalue=8e-64,
Organism=Escherichia coli, GI1789274, Length=390, Percent_Identity=31.7948717948718, Blast_Score=186, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI25146631, Length=430, Percent_Identity=30, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6321694, Length=452, Percent_Identity=28.3185840707965, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19920760, Length=421, Percent_Identity=30.166270783848, Blast_Score=182, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 45172; Mature: 45172

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQSVDVVIIGGGMVGLALAAALKESDLRIAVVENQLPEEALNPLPDVRVSALSRSSEIV
CCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCCCHHHHHCCCCCEE
LRNLNAWAGIEARRAAPYIAMEVWEQDSFARIEFKANEMTQPNLGHIVENRVIQLALFEQ
EEECCHHCCCCHHHCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
VQQQANVTLHVPATCQSIAVGESEAWLTLSNGQALSAKLVVGADGANSWLRRQMDIPLTH
HHHHCCEEEEECCCCCCEECCCCCEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCEEE
WDYGHSALVANVRTSDPHNKVARQIFTAQGPLAFLPMSEPHMSSIVWSTEPSRAEALLNM
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHEEECCCCHHHHHHHCC
NDVQFNKALTAEFDARLGRCEVVGERQAFPLKMRYARDFVAPRVALVGDAAHTIHPLAGQ
CCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCHHHHCCCCCC
GVNLGLLDAACLAQELLSLWQQNRDIGDERNLRHYERWRKAEAAKMIAAMQGFRDLFEGD
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLIRGIGMRLVGQLPGAKDEIMKRALGLKGDLPELAKQVWLERAY
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MMQSVDVVIIGGGMVGLALAAALKESDLRIAVVENQLPEEALNPLPDVRVSALSRSSEIV
CCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCCCHHHHHCCCCCEE
LRNLNAWAGIEARRAAPYIAMEVWEQDSFARIEFKANEMTQPNLGHIVENRVIQLALFEQ
EEECCHHCCCCHHHCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
VQQQANVTLHVPATCQSIAVGESEAWLTLSNGQALSAKLVVGADGANSWLRRQMDIPLTH
HHHHCCEEEEECCCCCCEECCCCCEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCEEE
WDYGHSALVANVRTSDPHNKVARQIFTAQGPLAFLPMSEPHMSSIVWSTEPSRAEALLNM
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHEEECCCCHHHHHHHCC
NDVQFNKALTAEFDARLGRCEVVGERQAFPLKMRYARDFVAPRVALVGDAAHTIHPLAGQ
CCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCHHHHCCCCCC
GVNLGLLDAACLAQELLSLWQQNRDIGDERNLRHYERWRKAEAAKMIAAMQGFRDLFEGD
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLIRGIGMRLVGQLPGAKDEIMKRALGLKGDLPELAKQVWLERAY
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]