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The map label for this gene is yhdH [H]

Identifier: 147673593

GI number: 147673593

Start: 1991565

End: 1992920

Strand: Reverse

Name: yhdH [H]

Synonym: VC0395_A1873

Alternate gene names: 147673593

Gene position: 1992920-1991565 (Counterclockwise)

Preceding gene: 147675568

Following gene: 147675075

Centisome position: 65.9

GC content: 48.3

Gene sequence:

>1356_bases
ATGGCACAATCAAATTCTCGTGAGACATTCAGCTCTCGCCTCGGTTTTATTCTTGCGGCTGCTGGAGCTGCAGTCGGTTT
AGGTAATATTTGGGGGTTTCCTACTCAAGCGGCCAGCAATGGTGGCGGCGCATTTTTGTTGGTCTACCTTATTTTGATCT
TTGTGGTCGCCTTCCCGATGTTGGTCGTGGAAATGGCGATTGGCCGCTATGGTCAAGCTAACCCTGTCGATAGTATGCGT
TCACTCACCTCTCAACCTGCTGCGAAAAAAGTCGGTGGATTCGTTGGTTGGGTTGGCCTTAGTGTACCCAGTGCCGTCTT
GGCCTTTTACAGCATTGTGGGTGGCTGGATTATCTGTTTTTTACTGGGAGCCATGACCGATCTGTTTGGTTTCACCGCGG
CAAGTGCGTGGCTGAAAGGATTCAGTGTCGAACGTAATCTTTTTGGTACGCTGATTTTTTATGTGTTAACGATCTTGATT
GTGCAGGGTGGCGTGAAGCAGGGGATTGAGCGCTGGTCAACCCGACTCATGCCTGCTCTATTTGTGCTGTTTGCCGTGCT
GTTTATCTACATCATGACTCAGCAAGGGGCTTGGGAAGGATTGAAGCATTATCTGATCCCTGATTTTGAAAAAGTGTGGG
ATCGTAAATTGATCTTGGCGGCAATGGGACAGGGATTCTTCTCATTAACCATTGGGGGTTGTTCGATGCTGATTTACGGC
TCTTATCTGAGTAAGAAAGAGAACTTGCCGAAAATGGCGATGAGCGTGACCTTGGTGGATACAGCGGTGGCTTTTATTGC
TGGTTTGGTGGTGTTGCCAGCAATGTTTGTGGCAATGAATAAAGGCGTGCAGATTTATGCGCAAGATGGCTCTTTGCTGA
GCTCTGATACCTTAGTCTTTACCGTATTACCTTTGATGTTTGATAGCTTGGGCTTACTGGGACAGATTTTCGCCATGGTG
TTTTTCCTTCTGCTCACCATCGCTGCGCTCACTTCTTCTATCTCTATGCTTGAATGTCCGGTTGCACTGGTGGGTGAGCG
TTTCAATACTCGCCGTACGCCAACCAGCTGGGTGTTGGGCGGTTTGATTGCCCTGTTCAGTGTGGTGATTGTCTATAACT
TTGGTGCCCTGTTTGGTTTGGTTGCCACTCTAGCGACGCAATATTTGCAGCCTACTGCCGCCTTAATGTTCTGTCTCTTT
GGTGGTTGGGTATGGCAGCGTGATGCCAAAATGAAAGAGCTGCAAGCCGGATTTCCGGAACTGCAACAAAGCTTATTTGG
CAAAATCTGGCCTTGGTATGTGAAATTTGTCTGCCCGGTTTTAGTGGCGACAGTGATTTGGGCTTCGTTTGGCTAA

Upstream 100 bases:

>100_bases
GGGTGATTTTTCAGCGAATGATTCTGTTGCTGATTGAGTCAATCTCCGCTTTGTATTAATGTACTAGTTAACTAGTGTGT
TGGTATCGTGAGTCGTCGTA

Downstream 100 bases:

>100_bases
ATAAAGCGCGGCTGGCGTAAGAAAAAGCCCTCATGATGAGGGCTTTTTCTATTGAGCAGATGCGGTATTTAGAGAGTGAC
AAGATGTCCTGTGGTTAAGG

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MAQSNSRETFSSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLILIFVVAFPMLVVEMAIGRYGQANPVDSMR
SLTSQPAAKKVGGFVGWVGLSVPSAVLAFYSIVGGWIICFLLGAMTDLFGFTAASAWLKGFSVERNLFGTLIFYVLTILI
VQGGVKQGIERWSTRLMPALFVLFAVLFIYIMTQQGAWEGLKHYLIPDFEKVWDRKLILAAMGQGFFSLTIGGCSMLIYG
SYLSKKENLPKMAMSVTLVDTAVAFIAGLVVLPAMFVAMNKGVQIYAQDGSLLSSDTLVFTVLPLMFDSLGLLGQIFAMV
FFLLLTIAALTSSISMLECPVALVGERFNTRRTPTSWVLGGLIALFSVVIVYNFGALFGLVATLATQYLQPTAALMFCLF
GGWVWQRDAKMKELQAGFPELQQSLFGKIWPWYVKFVCPVLVATVIWASFG

Sequences:

>Translated_451_residues
MAQSNSRETFSSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLILIFVVAFPMLVVEMAIGRYGQANPVDSMR
SLTSQPAAKKVGGFVGWVGLSVPSAVLAFYSIVGGWIICFLLGAMTDLFGFTAASAWLKGFSVERNLFGTLIFYVLTILI
VQGGVKQGIERWSTRLMPALFVLFAVLFIYIMTQQGAWEGLKHYLIPDFEKVWDRKLILAAMGQGFFSLTIGGCSMLIYG
SYLSKKENLPKMAMSVTLVDTAVAFIAGLVVLPAMFVAMNKGVQIYAQDGSLLSSDTLVFTVLPLMFDSLGLLGQIFAMV
FFLLLTIAALTSSISMLECPVALVGERFNTRRTPTSWVLGGLIALFSVVIVYNFGALFGLVATLATQYLQPTAALMFCLF
GGWVWQRDAKMKELQAGFPELQQSLFGKIWPWYVKFVCPVLVATVIWASFG
>Mature_450_residues
AQSNSRETFSSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLILIFVVAFPMLVVEMAIGRYGQANPVDSMRS
LTSQPAAKKVGGFVGWVGLSVPSAVLAFYSIVGGWIICFLLGAMTDLFGFTAASAWLKGFSVERNLFGTLIFYVLTILIV
QGGVKQGIERWSTRLMPALFVLFAVLFIYIMTQQGAWEGLKHYLIPDFEKVWDRKLILAAMGQGFFSLTIGGCSMLIYGS
YLSKKENLPKMAMSVTLVDTAVAFIAGLVVLPAMFVAMNKGVQIYAQDGSLLSSDTLVFTVLPLMFDSLGLLGQIFAMVF
FLLLTIAALTSSISMLECPVALVGERFNTRRTPTSWVLGGLIALFSVVIVYNFGALFGLVATLATQYLQPTAALMFCLFG
GWVWQRDAKMKELQAGFPELQQSLFGKIWPWYVKFVCPVLVATVIWASFG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=426, Percent_Identity=25.5868544600939, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI21361581, Length=379, Percent_Identity=24.2744063324538, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI171184408, Length=385, Percent_Identity=25.1948051948052, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI171184406, Length=385, Percent_Identity=25.1948051948052, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI171184404, Length=385, Percent_Identity=25.1948051948052, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI134304856, Length=469, Percent_Identity=24.3070362473348, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4507041, Length=455, Percent_Identity=24.3956043956044, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI188528618, Length=379, Percent_Identity=24.802110817942, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI197276623, Length=331, Percent_Identity=23.5649546827795, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI54607094, Length=331, Percent_Identity=23.5649546827795, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI289191351, Length=404, Percent_Identity=24.7524752475248, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4557046, Length=404, Percent_Identity=24.7524752475248, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI289191377, Length=404, Percent_Identity=24.7524752475248, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI7657587, Length=391, Percent_Identity=23.2736572890026, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI11181770, Length=298, Percent_Identity=27.5167785234899, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI58219014, Length=365, Percent_Identity=22.1917808219178, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI194018524, Length=324, Percent_Identity=26.2345679012346, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI12408638, Length=272, Percent_Identity=25.7352941176471, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI33354281, Length=303, Percent_Identity=23.4323432343234, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI5032097, Length=335, Percent_Identity=25.0746268656716, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI92859670, Length=120, Percent_Identity=35.8333333333333, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI21361693, Length=113, Percent_Identity=34.5132743362832, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI51468073, Length=308, Percent_Identity=23.0519480519481, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI218563756, Length=335, Percent_Identity=25.6716417910448, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI197276625, Length=69, Percent_Identity=44.9275362318841, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI6005715, Length=168, Percent_Identity=26.1904761904762, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=494, Percent_Identity=25.9109311740891, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71995588, Length=388, Percent_Identity=25, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25146584, Length=410, Percent_Identity=22.9268292682927, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17535731, Length=144, Percent_Identity=32.6388888888889, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI212642127, Length=121, Percent_Identity=35.5371900826446, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17542050, Length=115, Percent_Identity=34.7826086956522, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281365034, Length=397, Percent_Identity=25.1889168765743, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19921352, Length=399, Percent_Identity=24.812030075188, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24584353, Length=399, Percent_Identity=24.812030075188, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24762620, Length=392, Percent_Identity=25.765306122449, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI45551088, Length=391, Percent_Identity=25.8312020460358, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24652942, Length=391, Percent_Identity=25.8312020460358, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136952, Length=413, Percent_Identity=23.728813559322, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281364394, Length=386, Percent_Identity=23.5751295336788, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574704, Length=386, Percent_Identity=23.5751295336788, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17136950, Length=386, Percent_Identity=23.5751295336788, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574702, Length=386, Percent_Identity=23.5751295336788, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639514, Length=509, Percent_Identity=23.9685658153242, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI221329674, Length=509, Percent_Identity=23.9685658153242, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24639516, Length=528, Percent_Identity=23.8636363636364, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24655079, Length=301, Percent_Identity=25.2491694352159, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281364136, Length=425, Percent_Identity=24.7058823529412, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24639853, Length=411, Percent_Identity=23.6009732360097, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24654186, Length=300, Percent_Identity=25, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550877, Length=69, Percent_Identity=44.9275362318841, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551183, Length=69, Percent_Identity=44.9275362318841, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24661428, Length=194, Percent_Identity=24.2268041237113, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363702, Length=195, Percent_Identity=27.1794871794872, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19921936, Length=178, Percent_Identity=25.2808988764045, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48993; Mature: 48862

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQSNSRETFSSRLGFILAAAGAAVGLGNIWGFPTQAASNGGGAFLLVYLILIFVVAFPM
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]