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The map label for this gene is adrA [H]

Identifier: 147673586

GI number: 147673586

Start: 664438

End: 665907

Strand: Direct

Name: adrA [H]

Synonym: VC0395_A0622

Alternate gene names: 147673586

Gene position: 664438-665907 (Clockwise)

Preceding gene: 147675581

Following gene: 147674463

Centisome position: 21.97

GC content: 44.76

Gene sequence:

>1470_bases
ATGAATCAGCGCATGAGTTTAACTTGGATTATCTGTGCGCCACTGTTTATCGTTTTTGTGCTGGCCGCATCGGTCTTTCA
GCAATATCTGTACGATCTTAACCAAGAAATTGACGACGCCTACGCTGACATTCAACAGCAGCTTGAGCGCGCCGAAAAAG
TGGTGACAGCGCTGGATTACACTTTCACGCATAATCAACGCCCGGCAGAGAATATATTGTTTAAACACTCAGCCCGTGTG
GTTGCGAATGTTTGCCAAATCAAACCGATAGATGGGTTAGTTCTGGCTCAGGGGCTGAGTTCCAGCTTTGCTGTTCCCAA
ATTAGATCTAAGTTATATGCTGATTGGGGATGCCTCGTTATGCGATTCCAAACCAAGTCATGATCCCAGTTTACAAATCA
AACTCTCCATGGCTCCTATACTCTCGTTTTTGCATGACATGGATGAATATATTTATGGTGTGCATTATGTGGATAGCAGC
GGTTATATCATTTCATCGCCGGATACCATCAGCGAAAAGGTAACCTATCAGCAAATTAAAGACTTTATCAGCGAGAGTCC
TTTGTGGAGCCATGCGATTGCTGCCCCCAATATGATTGCCGTTGATGGGCCTTATCGCTCAGTGATCAGAGAGCAACATG
AGTGGTTATTAACACTGATTCTGCCCGTTTACCGTGACGCGGATTATCAAGGACTCGTTGCGGTAGATATTGGTTTACGC
GAACTGCTTAGCCGCATGCCTCATTTAGCATCTCGTTTTGACATGATTGATTTGAATGAGATGGCTATTCCAACGTTTGC
CTATCGTCCACACAAGCTCACCAGTGAATATGCAGACTATCATCAGGTGGTATTTTATAAGTTGGATATTCAGTCCGAAT
TGAGCAATTTTCTTACTGAGAAGAGCGGTAATTTACTGGTCGTTGCTCTGGTGTACCTCTTTCTCACAGGCGTACTTATC
TATCTCAATACGCGCTGGGATCGCCAGCATTATGCGCAGCTCGCCGCGCGTGATCCGATGACGGGTTTACTCAATCGACG
TGGTATGGAAAGCTTTCTGAAAGGCAAACGCCACAGTCAATATTTAGCCATTGCCGTGTTGGATATCGATGACTTCAAAC
AGATCAATGATGCTTATGGTCATGATATGGGGGATAGAGTGATCTGCTACATTGGTGAGCAGATTGAAAACCATATTCGT
AGCTCAGATGCCGTGGCACGCTTTGGTGGCGAAGAATTTGTGGTTTATGTCACAGCAAAAGAAAAAGAGCAGATCACGAG
AATTATGCAGCGCATTTTTGATGCGGTTTGCCGCGAGTCCCCTTTAATACTAGAGCCAGGTTTTACCATCTCTGGTGGGA
TAGAGGTGGTTGAAAGTACAACCGATCGCAGTTTTGAAGATTTGTTTAAAGCCGCTGATGAAAAGTTGTATGTAGCGAAA
ACCAGCGGCAAAAATCAGTTGGTTTACTGA

Upstream 100 bases:

>100_bases
TGTGTTTTTTGGCATAATCGCCGCAACGCAATATCCCTACCCATCATAAGCGTTATCGGTTTATGGTGGGTTTTTCATTT
CTAGAGGTTAGCAGGCAATT

Downstream 100 bases:

>100_bases
TCAGTTGATTTACTGATTCGTTGTTTTACTCATTAGACAGGTAGCTCGGCCGCAGCATGATGGAGTTGATCGCGATAGCG
ATGTAACTGATCAACGATCG

Product: GGDEF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MNQRMSLTWIICAPLFIVFVLAASVFQQYLYDLNQEIDDAYADIQQQLERAEKVVTALDYTFTHNQRPAENILFKHSARV
VANVCQIKPIDGLVLAQGLSSSFAVPKLDLSYMLIGDASLCDSKPSHDPSLQIKLSMAPILSFLHDMDEYIYGVHYVDSS
GYIISSPDTISEKVTYQQIKDFISESPLWSHAIAAPNMIAVDGPYRSVIREQHEWLLTLILPVYRDADYQGLVAVDIGLR
ELLSRMPHLASRFDMIDLNEMAIPTFAYRPHKLTSEYADYHQVVFYKLDIQSELSNFLTEKSGNLLVVALVYLFLTGVLI
YLNTRWDRQHYAQLAARDPMTGLLNRRGMESFLKGKRHSQYLAIAVLDIDDFKQINDAYGHDMGDRVICYIGEQIENHIR
SSDAVARFGGEEFVVYVTAKEKEQITRIMQRIFDAVCRESPLILEPGFTISGGIEVVESTTDRSFEDLFKAADEKLYVAK
TSGKNQLVY

Sequences:

>Translated_489_residues
MNQRMSLTWIICAPLFIVFVLAASVFQQYLYDLNQEIDDAYADIQQQLERAEKVVTALDYTFTHNQRPAENILFKHSARV
VANVCQIKPIDGLVLAQGLSSSFAVPKLDLSYMLIGDASLCDSKPSHDPSLQIKLSMAPILSFLHDMDEYIYGVHYVDSS
GYIISSPDTISEKVTYQQIKDFISESPLWSHAIAAPNMIAVDGPYRSVIREQHEWLLTLILPVYRDADYQGLVAVDIGLR
ELLSRMPHLASRFDMIDLNEMAIPTFAYRPHKLTSEYADYHQVVFYKLDIQSELSNFLTEKSGNLLVVALVYLFLTGVLI
YLNTRWDRQHYAQLAARDPMTGLLNRRGMESFLKGKRHSQYLAIAVLDIDDFKQINDAYGHDMGDRVICYIGEQIENHIR
SSDAVARFGGEEFVVYVTAKEKEQITRIMQRIFDAVCRESPLILEPGFTISGGIEVVESTTDRSFEDLFKAADEKLYVAK
TSGKNQLVY
>Mature_489_residues
MNQRMSLTWIICAPLFIVFVLAASVFQQYLYDLNQEIDDAYADIQQQLERAEKVVTALDYTFTHNQRPAENILFKHSARV
VANVCQIKPIDGLVLAQGLSSSFAVPKLDLSYMLIGDASLCDSKPSHDPSLQIKLSMAPILSFLHDMDEYIYGVHYVDSS
GYIISSPDTISEKVTYQQIKDFISESPLWSHAIAAPNMIAVDGPYRSVIREQHEWLLTLILPVYRDADYQGLVAVDIGLR
ELLSRMPHLASRFDMIDLNEMAIPTFAYRPHKLTSEYADYHQVVFYKLDIQSELSNFLTEKSGNLLVVALVYLFLTGVLI
YLNTRWDRQHYAQLAARDPMTGLLNRRGMESFLKGKRHSQYLAIAVLDIDDFKQINDAYGHDMGDRVICYIGEQIENHIR
SSDAVARFGGEEFVVYVTAKEKEQITRIMQRIFDAVCRESPLILEPGFTISGGIEVVESTTDRSFEDLFKAADEKLYVAK
TSGKNQLVY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=190, Percent_Identity=31.5789473684211, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87081881, Length=160, Percent_Identity=38.125, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=32.7044025157233, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=34.9693251533742, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=31.9018404907975, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI87081974, Length=289, Percent_Identity=27.3356401384083, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787816, Length=155, Percent_Identity=31.6129032258064, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787802, Length=165, Percent_Identity=32.1212121212121, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081977, Length=165, Percent_Identity=32.1212121212121, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788085, Length=189, Percent_Identity=31.2169312169312, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=32.3170731707317, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787541, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787056, Length=153, Percent_Identity=30.718954248366, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788381, Length=183, Percent_Identity=28.4153005464481, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 55594; Mature: 55594

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRMSLTWIICAPLFIVFVLAASVFQQYLYDLNQEIDDAYADIQQQLERAEKVVTALDY
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFTHNQRPAENILFKHSARVVANVCQIKPIDGLVLAQGLSSSFAVPKLDLSYMLIGDASL
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCHH
CDSKPSHDPSLQIKLSMAPILSFLHDMDEYIYGVHYVDSSGYIISSPDTISEKVTYQQIK
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHEEEEEECCCCEEEECCCHHHHHHHHHHHH
DFISESPLWSHAIAAPNMIAVDGPYRSVIREQHEWLLTLILPVYRDADYQGLVAVDIGLR
HHHHCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
ELLSRMPHLASRFDMIDLNEMAIPTFAYRPHKLTSEYADYHQVVFYKLDIQSELSNFLTE
HHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEEEHHHHHHHHHHC
KSGNLLVVALVYLFLTGVLIYLNTRWDRQHYAQLAARDPMTGLLNRRGMESFLKGKRHSQ
CCCCEEHHHHHHHHHHHHHEEEECCCCHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCC
YLAIAVLDIDDFKQINDAYGHDMGDRVICYIGEQIENHIRSSDAVARFGGEEFVVYVTAK
EEEEEEEECHHHHHHHHHHCCCCCCEEEEEECHHHHHHHCCCHHHHHCCCCEEEEEEECC
EKEQITRIMQRIFDAVCRESPLILEPGFTISGGIEVVESTTDRSFEDLFKAADEKLYVAK
CHHHHHHHHHHHHHHHHCCCCEEECCCCEECCCHHEEECCCCCCHHHHHHHCCCEEEEEE
TSGKNQLVY
CCCCCCCCC
>Mature Secondary Structure
MNQRMSLTWIICAPLFIVFVLAASVFQQYLYDLNQEIDDAYADIQQQLERAEKVVTALDY
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFTHNQRPAENILFKHSARVVANVCQIKPIDGLVLAQGLSSSFAVPKLDLSYMLIGDASL
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCHH
CDSKPSHDPSLQIKLSMAPILSFLHDMDEYIYGVHYVDSSGYIISSPDTISEKVTYQQIK
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHEEEEEECCCCEEEECCCHHHHHHHHHHHH
DFISESPLWSHAIAAPNMIAVDGPYRSVIREQHEWLLTLILPVYRDADYQGLVAVDIGLR
HHHHCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
ELLSRMPHLASRFDMIDLNEMAIPTFAYRPHKLTSEYADYHQVVFYKLDIQSELSNFLTE
HHHHHCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEEEHHHHHHHHHHC
KSGNLLVVALVYLFLTGVLIYLNTRWDRQHYAQLAARDPMTGLLNRRGMESFLKGKRHSQ
CCCCEEHHHHHHHHHHHHHEEEECCCCHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCC
YLAIAVLDIDDFKQINDAYGHDMGDRVICYIGEQIENHIRSSDAVARFGGEEFVVYVTAK
EEEEEEEECHHHHHHHHHHCCCCCCEEEEEECHHHHHHHCCCHHHHHCCCCEEEEEEECC
EKEQITRIMQRIFDAVCRESPLILEPGFTISGGIEVVESTTDRSFEDLFKAADEKLYVAK
CHHHHHHHHHHHHHHHHCCCCEEECCCCEECCCHHEEECCCCCCHHHHHHHCCCEEEEEE
TSGKNQLVY
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]