Click here to switch to the map view.

The map label for this gene is epsH

Identifier: 147673549

GI number: 147673549

Start: 2455215

End: 2455799

Strand: Reverse

Name: epsH

Synonym: VC0395_A2302

Alternate gene names: 147673549

Gene position: 2455799-2455215 (Counterclockwise)

Preceding gene: 147674515

Following gene: 147675768

Centisome position: 81.21

GC content: 51.11

Gene sequence:

>585_bases
ATGACAGCGACACGCGGTTTTACTTTGTTGGAAATTTTGCTGGTGCTGGTGCTGGTTTCGGCCAGTGCGGTGGCGGTCAT
CGCCACCTTTCCGGTTTCCGTCAAAGATGAAGCCAAAATCAGTGCGCAGAGTTTTTATCAGCGTCTGTTGCTGCTCAATG
AGGAAGCGATTCTCAGCGGGCAAGATTTTGGCGTGCGGATCGATGTCGATACGCGCCGTCTCACTTTTTTGCAACTCACC
GCCGACAAAGGTTGGCAAAAGTGGCAAAACGACAAGATGACCAACCAAACCACCCTTAAAGAAGGGTTACAGCTCGACTT
TGAACTCGGTGGTGGCGCTTGGCAAAAAGACGATCGTCTGTTTAATCCCGGCTCTCTGTTTGATGAAGAGATGTTTGCCG
ATGAGAAAAAAGAGCAAAAACAGGAACCGGCTCCGCAACTGTTTGTGCTATCGAGTGGCGAAGTGACCCCATTTACGCTG
AGCATTTTCCCTAAAGGGCAGGAGCCCGATGAGCAGTGGCGAGTGACCGCGCAAGAAAATGGCACTCTGCGTCTACTGGC
TCCGGGAGAAAGTGATGAAGAGTAA

Upstream 100 bases:

>100_bases
CGGTCAAGAAGGTGGTGAAGGTACCGGTGCCGATATCGGTAACTGGAATATCCAAGATTTTCAATAAGCTTGGCTAATTA
GCGGTAACTGACGGAACCTT

Downstream 100 bases:

>100_bases
ACGCGGTTTTACTTTGCTTGAAGTGCTGGTCGCGCTGGCAATTTTTGCTACCGCGGCGATCAGTGTGATCCGCTCGGTCA
GTCAACACATCAATACGGTC

Product: general secretion pathway protein H

Products: NA

Alternate protein names: Cholera toxin secretion protein epsH

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MTATRGFTLLEILLVLVLVSASAVAVIATFPVSVKDEAKISAQSFYQRLLLLNEEAILSGQDFGVRIDVDTRRLTFLQLT
ADKGWQKWQNDKMTNQTTLKEGLQLDFELGGGAWQKDDRLFNPGSLFDEEMFADEKKEQKQEPAPQLFVLSSGEVTPFTL
SIFPKGQEPDEQWRVTAQENGTLRLLAPGESDEE

Sequences:

>Translated_194_residues
MTATRGFTLLEILLVLVLVSASAVAVIATFPVSVKDEAKISAQSFYQRLLLLNEEAILSGQDFGVRIDVDTRRLTFLQLT
ADKGWQKWQNDKMTNQTTLKEGLQLDFELGGGAWQKDDRLFNPGSLFDEEMFADEKKEQKQEPAPQLFVLSSGEVTPFTL
SIFPKGQEPDEQWRVTAQENGTLRLLAPGESDEE
>Mature_193_residues
TATRGFTLLEILLVLVLVSASAVAVIATFPVSVKDEAKISAQSFYQRLLLLNEEAILSGQDFGVRIDVDTRRLTFLQLTA
DKGWQKWQNDKMTNQTTLKEGLQLDFELGGGAWQKDDRLFNPGSLFDEEMFADEKKEQKQEPAPQLFVLSSGEVTPFTLS
IFPKGQEPDEQWRVTAQENGTLRLLAPGESDEE

Specific function: Required for secretion of cholera toxin through the outer membrane

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP H family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GSPH_VIBCH (P45774)

Other databases:

- EMBL:   L33796
- EMBL:   AE003852
- PIR:   C82041
- RefSeq:   NP_232356.1
- PDB:   2QV8
- PDBsum:   2QV8
- ProteinModelPortal:   P45774
- SMR:   P45774
- GeneID:   2614892
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC2729
- TIGR:   VC_2729
- HOGENOM:   HBG677547
- OMA:   FEPGSLF
- ProtClustDB:   CLSK874900
- InterPro:   IPR002416
- InterPro:   IPR012902
- InterPro:   IPR001120
- InterPro:   IPR022346
- PRINTS:   PR00885
- TIGRFAMs:   TIGR02532
- TIGRFAMs:   TIGR01708

Pfam domain/function: PF12019 GspH

EC number: NA

Molecular weight: Translated: 21756; Mature: 21625

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATRGFTLLEILLVLVLVSASAVAVIATFPVSVKDEAKISAQSFYQRLLLLNEEAILSG
CCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHEECC
QDFGVRIDVDTRRLTFLQLTADKGWQKWQNDKMTNQTTLKEGLQLDFELGGGAWQKDDRL
CCCEEEEEECCCEEEEEEEECCCCHHHHCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCE
FNPGSLFDEEMFADEKKEQKQEPAPQLFVLSSGEVTPFTLSIFPKGQEPDEQWRVTAQEN
ECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHEEEEECCC
GTLRLLAPGESDEE
CEEEEEECCCCCCC
>Mature Secondary Structure 
TATRGFTLLEILLVLVLVSASAVAVIATFPVSVKDEAKISAQSFYQRLLLLNEEAILSG
CCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHEECC
QDFGVRIDVDTRRLTFLQLTADKGWQKWQNDKMTNQTTLKEGLQLDFELGGGAWQKDDRL
CCCEEEEEECCCEEEEEEEECCCCHHHHCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCE
FNPGSLFDEEMFADEKKEQKQEPAPQLFVLSSGEVTPFTLSIFPKGQEPDEQWRVTAQEN
ECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHEEEEECCC
GTLRLLAPGESDEE
CEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301