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The map label for this gene is aroB [H]

Identifier: 147673423

GI number: 147673423

Start: 2353222

End: 2354322

Strand: Reverse

Name: aroB [H]

Synonym: VC0395_A2205

Alternate gene names: 147673423

Gene position: 2354322-2353222 (Counterclockwise)

Preceding gene: 147675064

Following gene: 147675481

Centisome position: 77.85

GC content: 50.77

Gene sequence:

>1101_bases
TTGGAGTGCAAAACCATGGAGCGGATTACGGTCAACTTAGGTGAACGTAGCTACCCAATCTCAATCGGTGCCGGATTGTT
TGCCAATCCGGCTCTTCTTTCCCTCTCTGCTAAGCAGAAGGTGGTGATAGTCACCAACCACACTGTCGCTCCGCTGTATG
CGCCTGCGATCATTTCATTACTTGATCACATCGGTTGCCAGCATGCTTTGCTGGAACTGCCCGATGGCGAACAGTACAAA
ACTCTCGAAACCTTCAACACTGTGATGAGCTTTTTGCTTGAGCATAACTACAGCCGTGATGTGGTTGTCATTGCTTTAGG
TGGGGGAGTGATTGGTGATCTGGTCGGTTTCGCGGCGGCTTGTTATCAGCGTGGCGTTGATTTCATTCAAATACCGACCA
CACTGCTGTCGCAGGTGGATTCTTCGGTCGGTGGGAAAACCGCGGTCAATCATCCGCTCGGTAAAAACATGATTGGTGCT
TTTTATCAACCCAAAGCGGTAGTGATTGATACGGACTGTTTGACTACACTGCCCGCCCGTGAATTTGCCGCTGGCATGGC
GGAAGTCATCAAGTACGGCATCATTTACGACTCAGCCTTCTTCGACTGGCTAGAAGCACAGATGGAGGCCTTGTACGCAT
TGGACGAACAAGCGCTCACTTACGCAATTGCGCGCTGCTGCCAAATCAAAGCCGAGGTGGTCGCGCAAGATGAGAAAGAG
TCGGGCATTCGTGCGTTACTCAATCTTGGTCACACCTTCGGCCATGCAATTGAAGCACACATGGGCTATGGCAATTGGCT
GCACGGTGAAGCCGTATCTGCGGGTACAGTAATGGCGGCGAAAACGGCTCAATTACAAGGCCTTATCGATGCATCTCAAT
TTGAACGTATCCTAGCTATACTGAAAAAAGCGCATTTGCCTGTGCGAACCCCAGAGAACATGACCTTTGCCGATTTCATG
CAGCACATGATGCGCGATAAAAAAGTGTTGGCAGGGGAACTGCGTTTGGTGTTACCGACCAGTATCGGCACGTCAGCGGT
CGTAAAAGGGGTACCTGAAGCCGTGATTGCCCAAGCGATAGAGTATTGTCGCACGGTGTAA

Upstream 100 bases:

>100_bases
TGCGGACATCACGGTACGCACTGACGATCAAAGTGCAAAAGTGGTAGCCAATCAGATCGTAAAAATGCTAGAAGAACACA
TAATGTAATGTTTCTTCGAA

Downstream 100 bases:

>100_bases
TCGAGAGACTTGCAGAACATTTTGATATCAGACAATTGTCATTAGGATGGCCCAATGAGCTTGGCACATGAACTGGATTT
AGAATCGCAAACTGAGTTAC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MECKTMERITVNLGERSYPISIGAGLFANPALLSLSAKQKVVIVTNHTVAPLYAPAIISLLDHIGCQHALLELPDGEQYK
TLETFNTVMSFLLEHNYSRDVVVIALGGGVIGDLVGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGA
FYQPKAVVIDTDCLTTLPAREFAAGMAEVIKYGIIYDSAFFDWLEAQMEALYALDEQALTYAIARCCQIKAEVVAQDEKE
SGIRALLNLGHTFGHAIEAHMGYGNWLHGEAVSAGTVMAAKTAQLQGLIDASQFERILAILKKAHLPVRTPENMTFADFM
QHMMRDKKVLAGELRLVLPTSIGTSAVVKGVPEAVIAQAIEYCRTV

Sequences:

>Translated_366_residues
MECKTMERITVNLGERSYPISIGAGLFANPALLSLSAKQKVVIVTNHTVAPLYAPAIISLLDHIGCQHALLELPDGEQYK
TLETFNTVMSFLLEHNYSRDVVVIALGGGVIGDLVGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGA
FYQPKAVVIDTDCLTTLPAREFAAGMAEVIKYGIIYDSAFFDWLEAQMEALYALDEQALTYAIARCCQIKAEVVAQDEKE
SGIRALLNLGHTFGHAIEAHMGYGNWLHGEAVSAGTVMAAKTAQLQGLIDASQFERILAILKKAHLPVRTPENMTFADFM
QHMMRDKKVLAGELRLVLPTSIGTSAVVKGVPEAVIAQAIEYCRTV
>Mature_366_residues
MECKTMERITVNLGERSYPISIGAGLFANPALLSLSAKQKVVIVTNHTVAPLYAPAIISLLDHIGCQHALLELPDGEQYK
TLETFNTVMSFLLEHNYSRDVVVIALGGGVIGDLVGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGA
FYQPKAVVIDTDCLTTLPAREFAAGMAEVIKYGIIYDSAFFDWLEAQMEALYALDEQALTYAIARCCQIKAEVVAQDEKE
SGIRALLNLGHTFGHAIEAHMGYGNWLHGEAVSAGTVMAAKTAQLQGLIDASQFERILAILKKAHLPVRTPENMTFADFM
QHMMRDKKVLAGELRLVLPTSIGTSAVVKGVPEAVIAQAIEYCRTV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=361, Percent_Identity=61.218836565097, Blast_Score=450, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6320332, Length=339, Percent_Identity=37.4631268436578, Blast_Score=201, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39642; Mature: 39642

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECKTMERITVNLGERSYPISIGAGLFANPALLSLSAKQKVVIVTNHTVAPLYAPAIISL
CCCCCCHHHEEECCCCCCCEEECCCCCCCCHHEEECCCCEEEEEECCCCHHHHHHHHHHH
LDHIGCQHALLELPDGEQYKTLETFNTVMSFLLEHNYSRDVVVIALGGGVIGDLVGFAAA
HHHHCHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
CYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKAVVIDTDCLTTLPAR
HHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCHHHHCCHH
EFAAGMAEVIKYGIIYDSAFFDWLEAQMEALYALDEQALTYAIARCCQIKAEVVAQDEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SGIRALLNLGHTFGHAIEAHMGYGNWLHGEAVSAGTVMAAKTAQLQGLIDASQFERILAI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHH
LKKAHLPVRTPENMTFADFMQHMMRDKKVLAGELRLVLPTSIGTSAVVKGVPEAVIAQAI
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCHHHHHHHH
EYCRTV
HHHHCC
>Mature Secondary Structure
MECKTMERITVNLGERSYPISIGAGLFANPALLSLSAKQKVVIVTNHTVAPLYAPAIISL
CCCCCCHHHEEECCCCCCCEEECCCCCCCCHHEEECCCCEEEEEECCCCHHHHHHHHHHH
LDHIGCQHALLELPDGEQYKTLETFNTVMSFLLEHNYSRDVVVIALGGGVIGDLVGFAAA
HHHHCHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
CYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKAVVIDTDCLTTLPAR
HHHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEECCHHHHCCHH
EFAAGMAEVIKYGIIYDSAFFDWLEAQMEALYALDEQALTYAIARCCQIKAEVVAQDEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SGIRALLNLGHTFGHAIEAHMGYGNWLHGEAVSAGTVMAAKTAQLQGLIDASQFERILAI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHH
LKKAHLPVRTPENMTFADFMQHMMRDKKVLAGELRLVLPTSIGTSAVVKGVPEAVIAQAI
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCHHHHHHHH
EYCRTV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]