Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 147673422

GI number: 147673422

Start: 1226978

End: 1227907

Strand: Reverse

Name: nahR [H]

Synonym: VC0395_A1167

Alternate gene names: 147673422

Gene position: 1227907-1226978 (Counterclockwise)

Preceding gene: 147673606

Following gene: 147673845

Centisome position: 40.6

GC content: 43.12

Gene sequence:

>930_bases
ATGGTCGCCCCCGAAATCAATTTGCGCAGCATTGATTTAAATTTATTAACGATTTTAGAAAAGTTATTGATTCATAAGCA
TATTAGCCAAGCCGCACAAGCATTGAATATGAGCCAACCCGCCGTCAGTCGAGCCCTCATGCGTTTGCGTGAACAATTTG
GTGATCCACTGCTGGTGAAAGTAAAAAATGAGTACCGATTAACCGCAAAAGGTGAGCGCCTCTGCAGTGAACTGGAGAGA
ACGCTCAATACCATTCGACACATGTTGGTAGATGACAAGTTTGACCCAATGCACTATTCCGGTGTGTTCACTATTGGTGC
ATTGGATTTCGAGATGATGATGATTGTGCCGAAATTGTTGGCGCGTTTTCAACAACGTGCCCCTAATTTGAAGTTACAAA
TCGTACCGTATAACGCCTATATGCCGCTGCATGATTACTTGGAAAAGGTGGCGGATTTACTGCTGTATTCCACTGATGAG
TCACCCACCAATGTGTTTAAGCAGCGTTTATTTAATGACAACTATGCTGTGGTCATGTGTAGAAACCATCCATTAGCCAA
TCAACCGATAACACTGGAGAGTTATTGCCAGAGTCGACATGTGATCATTTCCGGTAATGGTTTAGGAAAAACGGATATGG
ATCATGAGCTGAAAAAGCTCAATTATCAGCGCGAAGTGGTGGCATCGTTGCCACATTTTTCGATGGTGCCGGAGTTACTG
ATCAACACCGATCTGATTGCCACCTTACCAAGACGTTTGGTGACTCACTTAGGCCAGCGTTATGAGATAACCGTGGCTGA
TTTACCTTTCTATACTGCCGATTTTCGAGTGGAACAATTTTGGCATCTTATTCATCACAGTAGCCCGATTCATCAGTGGG
TGAGGCAAGAGATCAAAAATTTAGTCTATGAAGAGATCGATAAGAAATAA

Upstream 100 bases:

>100_bases
CAATCAGGTGGGGAAAAGATAAATGAGAAACAAACATATCAAAAATGCATGCTTGTTATAGTATGTATATCATTTACGCA
CGAAATTATTAGGTGATGAG

Downstream 100 bases:

>100_bases
TCTCCTATCAAATTTAAAACAAAAGGCTGCCATTCGGCAGCCTTGAAAGGGATGGTGAGATGGATTACACCAGATCAAAT
CGATCCGCATTCATTACTTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MVAPEINLRSIDLNLLTILEKLLIHKHISQAAQALNMSQPAVSRALMRLREQFGDPLLVKVKNEYRLTAKGERLCSELER
TLNTIRHMLVDDKFDPMHYSGVFTIGALDFEMMMIVPKLLARFQQRAPNLKLQIVPYNAYMPLHDYLEKVADLLLYSTDE
SPTNVFKQRLFNDNYAVVMCRNHPLANQPITLESYCQSRHVIISGNGLGKTDMDHELKKLNYQREVVASLPHFSMVPELL
INTDLIATLPRRLVTHLGQRYEITVADLPFYTADFRVEQFWHLIHHSSPIHQWVRQEIKNLVYEEIDKK

Sequences:

>Translated_309_residues
MVAPEINLRSIDLNLLTILEKLLIHKHISQAAQALNMSQPAVSRALMRLREQFGDPLLVKVKNEYRLTAKGERLCSELER
TLNTIRHMLVDDKFDPMHYSGVFTIGALDFEMMMIVPKLLARFQQRAPNLKLQIVPYNAYMPLHDYLEKVADLLLYSTDE
SPTNVFKQRLFNDNYAVVMCRNHPLANQPITLESYCQSRHVIISGNGLGKTDMDHELKKLNYQREVVASLPHFSMVPELL
INTDLIATLPRRLVTHLGQRYEITVADLPFYTADFRVEQFWHLIHHSSPIHQWVRQEIKNLVYEEIDKK
>Mature_309_residues
MVAPEINLRSIDLNLLTILEKLLIHKHISQAAQALNMSQPAVSRALMRLREQFGDPLLVKVKNEYRLTAKGERLCSELER
TLNTIRHMLVDDKFDPMHYSGVFTIGALDFEMMMIVPKLLARFQQRAPNLKLQIVPYNAYMPLHDYLEKVADLLLYSTDE
SPTNVFKQRLFNDNYAVVMCRNHPLANQPITLESYCQSRHVIISGNGLGKTDMDHELKKLNYQREVVASLPHFSMVPELL
INTDLIATLPRRLVTHLGQRYEITVADLPFYTADFRVEQFWHLIHHSSPIHQWVRQEIKNLVYEEIDKK

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=298, Percent_Identity=23.8255033557047, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI87081766, Length=303, Percent_Identity=24.7524752475248, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790147, Length=304, Percent_Identity=24.6710526315789, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789204, Length=213, Percent_Identity=26.7605633802817, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=26.7206477732794, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35941; Mature: 35941

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPEINLRSIDLNLLTILEKLLIHKHISQAAQALNMSQPAVSRALMRLREQFGDPLLVK
CCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEE
VKNEYRLTAKGERLCSELERTLNTIRHMLVDDKFDPMHYSGVFTIGALDFEMMMIVPKLL
ECCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
ARFQQRAPNLKLQIVPYNAYMPLHDYLEKVADLLLYSTDESPTNVFKQRLFNDNYAVVMC
HHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEE
RNHPLANQPITLESYCQSRHVIISGNGLGKTDMDHELKKLNYQREVVASLPHFSMVPELL
CCCCCCCCCEEHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
INTDLIATLPRRLVTHLGQRYEITVADLPFYTADFRVEQFWHLIHHSSPIHQWVRQEIKN
HCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LVYEEIDKK
HHHHHHCCC
>Mature Secondary Structure
MVAPEINLRSIDLNLLTILEKLLIHKHISQAAQALNMSQPAVSRALMRLREQFGDPLLVK
CCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEE
VKNEYRLTAKGERLCSELERTLNTIRHMLVDDKFDPMHYSGVFTIGALDFEMMMIVPKLL
ECCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
ARFQQRAPNLKLQIVPYNAYMPLHDYLEKVADLLLYSTDESPTNVFKQRLFNDNYAVVMC
HHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEE
RNHPLANQPITLESYCQSRHVIISGNGLGKTDMDHELKKLNYQREVVASLPHFSMVPELL
CCCCCCCCCEEHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
INTDLIATLPRRLVTHLGQRYEITVADLPFYTADFRVEQFWHLIHHSSPIHQWVRQEIKN
HCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LVYEEIDKK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]