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The map label for this gene is fabF [H]

Identifier: 147673369

GI number: 147673369

Start: 1725867

End: 1727111

Strand: Reverse

Name: fabF [H]

Synonym: VC0395_A1605

Alternate gene names: 147673369

Gene position: 1727111-1725867 (Counterclockwise)

Preceding gene: 147673387

Following gene: 147673849

Centisome position: 57.11

GC content: 50.12

Gene sequence:

>1245_bases
GTGTCCAAGCGTCGCGTTGTTGTCACTGGCATGGGTATGTTGTCACCGGTAGGCAACACTGTAGAGTCATCTTGGAAAGC
CTTGTTGGCCGGCCAAAGCGGCATCGTCAACATTGAGCACTTCGACACTACCAATTTTTCTACTCGTTTCGCAGGCCTGG
TAAAAGGTTTTGACTGCGAACAGTACATGTCAAAAAAAGATGCTCGCAAAATGGATTTGTTTATCCAGTATGGTATCGCT
GCGGGCATTCAGGCTTTGGAAGATTCAGGCCTAGAAGTTAATGAAGAAAATGCTGCGCGTATTGGCGTTGCGATTGGTTC
GGGTATCGGCGGCCTTGAGCTGATTGAAACCGGACATCAAGCTTTAATCGAGAAAGGCCCACGTAAGGTTAGCCCTTTCT
TCGTTCCCTCAACTATTGTCAACATGATTGCCGGTAACTTGTCTATCATGCGTGGCTTACGTGGTCCCAATATTGCGATC
TCTACCGCCTGTACCACGGGCTTGCACAATATCGGCCATGCAGCACGTATGATTGCTTACGGTGATGCGGATGCGATGGT
TGCAGGTGGTGCAGAAAAAGCGTCAACGCCACTGGGCATGGCGGGTTTTGGTGCGGCGAAAGCACTCTCAACTCGTAATG
ATGAACCGCAAAAAGCGTCTCGTCCTTGGGATAAAGACCGTGATGGTTTCGTGCTCGGTGACGGTGCCGGCATCATGGTG
CTTGAAGAGTACGAACACGCGAAAGCGCGTGGCGCGAAAATTTACGCAGAAGTGGTTGGCTTCGGTATGTCAGGTGATGC
TTATCATATGACTTCACCGAGTGAAGACGGCTCTGGCGGTGCGCTGGCGATGGAAGCGGCCATGCGTGATGCAGGCGTGA
CTGGTGAGCAGATTGGTTATGTTAATGCTCACGGTACATCTACCCCTGCGGGCGATGTGGCTGAAGTGAAAGGCATTAAA
CGTGCGTTGGGTGAAGCAGGGACTAAGCAAGTTCTGGTTTCTTCTACCAAGTCCATGACGGGTCACTTATTAGGTGCTGC
AGGTTCTGTCGAAGCGATCATCACTGTGATGTCTTTGGTGGATCAAATGGTTCCACCGACCATCAATCTGGATAATCCTG
AAGAAGGTTTGGGTGTCGATTTAGTACCGCATGTTGCCCGTAAAGTTGAGAGTATGGAATACGCCATGTGTAACTCGTTT
GGCTTTGGTGGTACTAACGGTAGCTTGATTTTCAAGCGCATGTAA

Upstream 100 bases:

>100_bases
AACGCTCAGTAATCTCTCCTCAGGCGGCTCACTGGCCGCCTGAATTTTTCTTAGTTCTCAACCCTCTCTCATTTCAATTT
CAATTCCGGAGAATATTATC

Downstream 100 bases:

>100_bases
AAACTTCATCACTCTTTACTTGAGTTAAGACGGCTTGATGCATAGCATTGAGCCGTTTCTTTTTATGGAGTGAGAGCATG
TACTGGGTCAATGGTCAACG

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSKRRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVKGFDCEQYMSKKDARKMDLFIQYGIA
AGIQALEDSGLEVNEENAARIGVAIGSGIGGLELIETGHQALIEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAI
STACTTGLHNIGHAARMIAYGDADAMVAGGAEKASTPLGMAGFGAAKALSTRNDEPQKASRPWDKDRDGFVLGDGAGIMV
LEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDAGVTGEQIGYVNAHGTSTPAGDVAEVKGIK
RALGEAGTKQVLVSSTKSMTGHLLGAAGSVEAIITVMSLVDQMVPPTINLDNPEEGLGVDLVPHVARKVESMEYAMCNSF
GFGGTNGSLIFKRM

Sequences:

>Translated_414_residues
MSKRRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVKGFDCEQYMSKKDARKMDLFIQYGIA
AGIQALEDSGLEVNEENAARIGVAIGSGIGGLELIETGHQALIEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAI
STACTTGLHNIGHAARMIAYGDADAMVAGGAEKASTPLGMAGFGAAKALSTRNDEPQKASRPWDKDRDGFVLGDGAGIMV
LEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDAGVTGEQIGYVNAHGTSTPAGDVAEVKGIK
RALGEAGTKQVLVSSTKSMTGHLLGAAGSVEAIITVMSLVDQMVPPTINLDNPEEGLGVDLVPHVARKVESMEYAMCNSF
GFGGTNGSLIFKRM
>Mature_413_residues
SKRRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVKGFDCEQYMSKKDARKMDLFIQYGIAA
GIQALEDSGLEVNEENAARIGVAIGSGIGGLELIETGHQALIEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAIS
TACTTGLHNIGHAARMIAYGDADAMVAGGAEKASTPLGMAGFGAAKALSTRNDEPQKASRPWDKDRDGFVLGDGAGIMVL
EEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDAGVTGEQIGYVNAHGTSTPAGDVAEVKGIKR
ALGEAGTKQVLVSSTKSMTGHLLGAAGSVEAIITVMSLVDQMVPPTINLDNPEEGLGVDLVPHVARKVESMEYAMCNSFG
FGGTNGSLIFKRM

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=47.1153846153846, Blast_Score=354, Evalue=9e-98,
Organism=Homo sapiens, GI223972627, Length=171, Percent_Identity=46.7836257309941, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI41872631, Length=428, Percent_Identity=24.5327102803738, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1787337, Length=414, Percent_Identity=75.1207729468599, Blast_Score=614, Evalue=1e-177,
Organism=Escherichia coli, GI1788663, Length=417, Percent_Identity=37.8896882494005, Blast_Score=242, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI71983541, Length=414, Percent_Identity=40.0966183574879, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71983535, Length=266, Percent_Identity=44.7368421052632, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI212642053, Length=429, Percent_Identity=24.7086247086247, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=415, Percent_Identity=24.3373493975904, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6320904, Length=443, Percent_Identity=38.3747178329571, Blast_Score=286, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24644341, Length=429, Percent_Identity=45.2214452214452, Blast_Score=344, Evalue=8e-95,
Organism=Drosophila melanogaster, GI19920632, Length=382, Percent_Identity=24.0837696335079, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221330659, Length=382, Percent_Identity=24.0837696335079, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24581345, Length=389, Percent_Identity=22.107969151671, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43209; Mature: 43078

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVKGFDCE
CCCCEEEEECCCHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCHH
QYMSKKDARKMDLFIQYGIAAGIQALEDSGLEVNEENAARIGVAIGSGIGGLELIETGHQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEECCCCCCHHHHHHHHH
ALIEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAISTACTTGLHNIGHAARMIAY
HHHHCCCCCCCCEECHHHHHHHHHCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHEEEE
GDADAMVAGGAEKASTPLGMAGFGAAKALSTRNDEPQKASRPWDKDRDGFVLGDGAGIMV
CCCCCEEECCCHHCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCCCCCCCEEEECCCCEEE
LEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDAGVTGEQIGY
EECCHHHHHCCCEEEEHHHCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHCCCCHHHEEE
VNAHGTSTPAGDVAEVKGIKRALGEAGTKQVLVSSTKSMTGHLLGAAGSVEAIITVMSLV
EECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DQMVPPTINLDNPEEGLGVDLVPHVARKVESMEYAMCNSFGFGGTNGSLIFKRM
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SKRRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVKGFDCE
CCCEEEEECCCHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCHH
QYMSKKDARKMDLFIQYGIAAGIQALEDSGLEVNEENAARIGVAIGSGIGGLELIETGHQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEECCCCCCHHHHHHHHH
ALIEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAISTACTTGLHNIGHAARMIAY
HHHHCCCCCCCCEECHHHHHHHHHCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHEEEE
GDADAMVAGGAEKASTPLGMAGFGAAKALSTRNDEPQKASRPWDKDRDGFVLGDGAGIMV
CCCCCEEECCCHHCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCCCCCCCEEEECCCCEEE
LEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDAGVTGEQIGY
EECCHHHHHCCCEEEEHHHCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHCCCCHHHEEE
VNAHGTSTPAGDVAEVKGIKRALGEAGTKQVLVSSTKSMTGHLLGAAGSVEAIITVMSLV
EECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DQMVPPTINLDNPEEGLGVDLVPHVARKVESMEYAMCNSFGFGGTNGSLIFKRM
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]