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The map label for this gene is sucC [H]

Identifier: 147673132

GI number: 147673132

Start: 1797165

End: 1798331

Strand: Reverse

Name: sucC [H]

Synonym: VC0395_A1671

Alternate gene names: 147673132

Gene position: 1798331-1797165 (Counterclockwise)

Preceding gene: 147675118

Following gene: 147673983

Centisome position: 59.47

GC content: 47.47

Gene sequence:

>1167_bases
ATGAATTTGCATGAATATCAAGCTAAACAGCTGTTTGCAGAATTCGGTTTGCCTGTACCGGAAGGTTATGCTTGTGATAC
GCCACAAGAAGCGTTTGAAGCTGCAGGACGCATCAGCACAGCCAAGAAAGTCGTAAAATGCCAAGTTCACGCAGGTGGAC
GTGGTAAAGCAGGTGGCGTTGAACTGCATGACACTAAAGAAGGCGTAAAAGCGTTTGCACAAAAATGGCTAGGTAAGAAC
CTAGTAACTTATCAAACGGATGCAAATGGCCAACCGGTTTCAAAAATTTTGGTTGAAGAAGCATCAAATATCGCTAATGA
GCTTTATCTTGGTGCGGTAGTTGACCGTTCTACACGTCGTATCGTTTTCATGGCATCGACTGAAGGTGGCGTGGAAATTG
AGAAAGTGGCAGAAGAAACTCCAGAACTGATCCACAAAGCGGCGATTGATCCACTGGTTGGCCCACAAGCCTACCAAGGT
CGTGAATTGGCGTTCAAGCTAGGCCTGCAAGGTGATCAAATCAAACAGTTCGTGAAAATCTTCATGGGCTTGGGTGAAAT
GTTTGCTCAATATGATCTCGCACTGCTGGAAATCAACCCGCTGGTGATTACTGCGGAAGGTAACTTGCTGTGCCTTGATG
GCAAAATCAACATCGACTCCAATGCTATGTACCGTCAACCCAAACTGCGTCAAATGCACGATGCTTCTCAAGAAGATGCG
CGCGAAGCACACGCAGCGAAATGGGAGCTTAACTACGTTGCGCTGGATGGTAACGTAGGCTGTATGGTTAACGGTGCTGG
CCTTGCGATGGGTACGATGGACATTGTTAACTTGCACGGCGGAAAACCCGCAAACTTCCTTGATGTTGGTGGCGGCGCGA
CCAAAGAGCGTGTTGCAGAAGCCTTCAAAATCATCTTGTCTGATACCAATGTAAAAGCCGTACTGGTGAACATCTTTGGT
GGCATTGTGCGCTGCGACATGATTGCAGAAGGCATTATCGGTGCAGTGAAGGAAGTTGGTGTAAGCGTTCCAGTGGTTGT
GCGTCTTGAAGGTACAAACGCAGAACTTGGACGTAAAGTACTGGCAGAATCAGGTCTAGATATTATTGCAGCTGTATCTT
TGACAGACGCAGCGCAAAAAGTAGTTGCCGCGGCGGAGGGCAAATAA

Upstream 100 bases:

>100_bases
TTTGGCCAAAGATTGGCTACTCGCTCAAGAGTGACCCTACAAACGTAAAGTTCAGCTCAATGGACTCTATGGAAGAACAA
TAAACAAATGGAACAACACA

Downstream 100 bases:

>100_bases
TGTCGATTCTTATCAATAAAGACACTAAAGTCATTTGTCAGGGTTTCACCGGTGGTCAAGGTACTTTCCACTCTGAACAG
GCGATTACTTATGGCACACA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKAFAQKWLGKN
LVTYQTDANGQPVSKILVEEASNIANELYLGAVVDRSTRRIVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQG
RELAFKLGLQGDQIKQFVKIFMGLGEMFAQYDLALLEINPLVITAEGNLLCLDGKINIDSNAMYRQPKLRQMHDASQEDA
REAHAAKWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDTNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNAELGRKVLAESGLDIIAAVSLTDAAQKVVAAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKAFAQKWLGKN
LVTYQTDANGQPVSKILVEEASNIANELYLGAVVDRSTRRIVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQG
RELAFKLGLQGDQIKQFVKIFMGLGEMFAQYDLALLEINPLVITAEGNLLCLDGKINIDSNAMYRQPKLRQMHDASQEDA
REAHAAKWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDTNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNAELGRKVLAESGLDIIAAVSLTDAAQKVVAAAEGK
>Mature_388_residues
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKAFAQKWLGKN
LVTYQTDANGQPVSKILVEEASNIANELYLGAVVDRSTRRIVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQG
RELAFKLGLQGDQIKQFVKIFMGLGEMFAQYDLALLEINPLVITAEGNLLCLDGKINIDSNAMYRQPKLRQMHDASQEDA
REAHAAKWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDTNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNAELGRKVLAESGLDIIAAVSLTDAAQKVVAAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=46.5648854961832, Blast_Score=353, Evalue=2e-97,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=45.1697127937337, Blast_Score=322, Evalue=3e-88,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=45.3038674033149, Blast_Score=304, Evalue=1e-82,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=77.319587628866, Blast_Score=601, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=45.360824742268, Blast_Score=317, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=41.9847328244275, Blast_Score=306, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=42.8571428571429, Blast_Score=330, Evalue=2e-91,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=43.6548223350254, Blast_Score=310, Evalue=8e-85,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=43.5114503816794, Blast_Score=307, Evalue=6e-84,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=43.5114503816794, Blast_Score=307, Evalue=6e-84,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=43.6548223350254, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=43.6548223350254, Blast_Score=305, Evalue=3e-83,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41399; Mature: 41399

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKAFAQKWLGKNLVTYQTDANGQPVSKILVEEASNIANELYLGAVVDRSTRR
EECCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCE
IVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQGRELAFKLGLQGDQIKQFVKI
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FMGLGEMFAQYDLALLEINPLVITAEGNLLCLDGKINIDSNAMYRQPKLRQMHDASQEDA
HHHHHHHHHHHCEEEEEECCEEEEECCCEEEECCEEEECCCCCCCCCHHHHHHCCCHHHH
REAHAAKWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDTNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNAELGRKV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LAESGLDIIAAVSLTDAAQKVVAAAEGK
HHHCCCCEEEEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKAFAQKWLGKNLVTYQTDANGQPVSKILVEEASNIANELYLGAVVDRSTRR
EECCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCE
IVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQGRELAFKLGLQGDQIKQFVKI
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FMGLGEMFAQYDLALLEINPLVITAEGNLLCLDGKINIDSNAMYRQPKLRQMHDASQEDA
HHHHHHHHHHHCEEEEEECCEEEEECCCEEEECCEEEECCCCCCCCCHHHHHHCCCHHHH
REAHAAKWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDTNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNAELGRKV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LAESGLDIIAAVSLTDAAQKVVAAAEGK
HHHCCCCEEEEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA