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The map label for this gene is ilvE [H]

Identifier: 146343667

GI number: 146343667

Start: 7179968

End: 7180843

Strand: Reverse

Name: ilvE [H]

Synonym: BRADO6909

Alternate gene names: 146343667

Gene position: 7180843-7179968 (Counterclockwise)

Preceding gene: 146343671

Following gene: 146343663

Centisome position: 96.3

GC content: 64.73

Gene sequence:

>876_bases
GTGAAGCCTGTCAGCTATTCGCAGACCTGGACGTTCTTCGACGGGGAATGGCGCGAGGGCAATGCGCCGATCATGGGTGT
TCGCACCCATGCGACCTGGCTGGCATCGACCGTGTTCGACGGCGCGCGCGCCTTCGAAGGGGTGGCACCCGACCTCGACC
GTCACTGCGCCCGGGTCAATCAATCGGCGCTCAATTTCCGGCTCAAGCCGGTGGTCGACGTGGCGACCTGGATCGGGCTG
GCCCACGAGGGCATCGCGCGGTTCGGCGCCAATGCGGAGCTCTACATCCGCCCGATGTACTGGGCGCAGCACGGCGCAGG
CGGCGGCGTGCTGTTCGATCCCGAGACGACCAATTGGTGCCTGTGCATCTACGAGGCGCCGATGCCGCAGCCGACCGGCA
ATGCGATCACGCTGTCGCCGTTCCGGCGGCCGACTGCCGAATGCGCGCCGGTCGATGCCAAGGCGGCGTGTCTCTATCCG
AACAATTCGCGCGCGTTGATCGAAGCGGCCTCGCGCGGCTTCAACAATTGCCTGATGCTGGATCTGCTCGGCAATGTCGC
CGAGTTCGGCAACGCCAACGTATTCATGGTCAAGGACGGCGTCGTGTTCACGCCGGTGCCGAATGGCACCTTCCTCAACG
GCATCACCCGCCAGCGCGTGATCGAGCTGCTGCGCGGCGACGGCGTCAGCTTGGTCGAGACAACGCTGCGCTACGAGGAT
TTTCTGAGTGCCGACGAGATATTCTCATCGGGGAACTTCGCCAAGGTCGCGCCGGTCATTCGCATTGACGACAGGATCCT
GCCGATCGGCCCGGTGTTCAGCCGTGCGCGGCGATTGTACTGGAACTATGCGCATGCGGTCAGGGCCGCCGCTTAG

Upstream 100 bases:

>100_bases
CGATCATGAGCAGCGCATCGGCAAGCAGATCCTTAAAATCTCCACGCCACAACGGCAGGATCAATTTCTGTCGAACGGGA
GCTCCCCCATGACCCATACC

Downstream 100 bases:

>100_bases
GTCAGGGGCCATAGAGCGGAAGCTCGGTATCGCTGAGATCGCCGAGCCGTGGCGGTTGCGGTCCCTTGATGTACTTCCGG
CCGCGGCGCTCAGTGTAGAC

Product: aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKPVSYSQTWTFFDGEWREGNAPIMGVRTHATWLASTVFDGARAFEGVAPDLDRHCARVNQSALNFRLKPVVDVATWIGL
AHEGIARFGANAELYIRPMYWAQHGAGGGVLFDPETTNWCLCIYEAPMPQPTGNAITLSPFRRPTAECAPVDAKAACLYP
NNSRALIEAASRGFNNCLMLDLLGNVAEFGNANVFMVKDGVVFTPVPNGTFLNGITRQRVIELLRGDGVSLVETTLRYED
FLSADEIFSSGNFAKVAPVIRIDDRILPIGPVFSRARRLYWNYAHAVRAAA

Sequences:

>Translated_291_residues
MKPVSYSQTWTFFDGEWREGNAPIMGVRTHATWLASTVFDGARAFEGVAPDLDRHCARVNQSALNFRLKPVVDVATWIGL
AHEGIARFGANAELYIRPMYWAQHGAGGGVLFDPETTNWCLCIYEAPMPQPTGNAITLSPFRRPTAECAPVDAKAACLYP
NNSRALIEAASRGFNNCLMLDLLGNVAEFGNANVFMVKDGVVFTPVPNGTFLNGITRQRVIELLRGDGVSLVETTLRYED
FLSADEIFSSGNFAKVAPVIRIDDRILPIGPVFSRARRLYWNYAHAVRAAA
>Mature_291_residues
MKPVSYSQTWTFFDGEWREGNAPIMGVRTHATWLASTVFDGARAFEGVAPDLDRHCARVNQSALNFRLKPVVDVATWIGL
AHEGIARFGANAELYIRPMYWAQHGAGGGVLFDPETTNWCLCIYEAPMPQPTGNAITLSPFRRPTAECAPVDAKAACLYP
NNSRALIEAASRGFNNCLMLDLLGNVAEFGNANVFMVKDGVVFTPVPNGTFLNGITRQRVIELLRGDGVSLVETTLRYED
FLSADEIFSSGNFAKVAPVIRIDDRILPIGPVFSRARRLYWNYAHAVRAAA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=287, Percent_Identity=27.5261324041812, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 32046; Mature: 32046

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVSYSQTWTFFDGEWREGNAPIMGVRTHATWLASTVFDGARAFEGVAPDLDRHCARVN
CCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
QSALNFRLKPVVDVATWIGLAHEGIARFGANAELYIRPMYWAQHGAGGGVLFDPETTNWC
HHHHCEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEECCCCCCEE
LCIYEAPMPQPTGNAITLSPFRRPTAECAPVDAKAACLYPNNSRALIEAASRGFNNCLML
EEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEEHH
DLLGNVAEFGNANVFMVKDGVVFTPVPNGTFLNGITRQRVIELLRGDGVSLVETTLRYED
HHHHHHHHHCCCCEEEEECCEEEEECCCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHH
FLSADEIFSSGNFAKVAPVIRIDDRILPIGPVFSRARRLYWNYAHAVRAAA
HCCHHHHHCCCCCEEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPVSYSQTWTFFDGEWREGNAPIMGVRTHATWLASTVFDGARAFEGVAPDLDRHCARVN
CCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
QSALNFRLKPVVDVATWIGLAHEGIARFGANAELYIRPMYWAQHGAGGGVLFDPETTNWC
HHHHCEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEECCCCCCEE
LCIYEAPMPQPTGNAITLSPFRRPTAECAPVDAKAACLYPNNSRALIEAASRGFNNCLML
EEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEEHH
DLLGNVAEFGNANVFMVKDGVVFTPVPNGTFLNGITRQRVIELLRGDGVSLVETTLRYED
HHHHHHHHHCCCCEEEEECCEEEEECCCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHH
FLSADEIFSSGNFAKVAPVIRIDDRILPIGPVFSRARRLYWNYAHAVRAAA
HCCHHHHHCCCCCEEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA