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The map label for this gene is exuT [H]

Identifier: 146343624

GI number: 146343624

Start: 7127825

End: 7129138

Strand: Reverse

Name: exuT [H]

Synonym: BRADO6863

Alternate gene names: 146343624

Gene position: 7129138-7127825 (Counterclockwise)

Preceding gene: 146343629

Following gene: 146343621

Centisome position: 95.61

GC content: 66.21

Gene sequence:

>1314_bases
ATGATGGCCGCGCCAACGACGCTCAAGAGCAATGCCCGCGCCAGCACGGCGTCCACGCCGAAGGGCGCGTGGAGGATCAC
CTTCCTTTTGTTTCTGTTCATGCTGGTGAACTTTGCCGACAAGATCGTTGTCGGCCTCGCCGGCGTTCCGATCATGACCG
AGCTCAATCTGAGCGCCGAGCAGTTCGGGCTGCTCGGCTCGTCGTTCTTCCTGCTGTTCTCCCTCGCGGCGATCGTGGTC
GGCTTCATCGTCAACAAGGTGCCGACGCGCTGGGTCCTCCTGGTGCTGGCGCTGGTGTGGGCGGTGGCGCAATTCCCGAT
GGTCGGCACCGTCGGCTTCACGACGCTGCTGATCTGCCGAATCATTCTCGGCGCCGGCGAAGGTCCGGCAGCCTCGGTCG
CGGTTCACGCGATCTACAAATGGTTTCCCGACGAGAAGCGCGCGATGCCGACCGCGATCCTGTCGCAGGGCTCCGCGTTC
GGCGTCATCCTCGCGGTGCCCGCCTTGAACTGGGTGATCGTGAATCATGGCTGGCACTATGCGTTCGGCGCGCTGGGCGT
GGTCGGCCTGATGTGGAGCGCGGCGTGGCTGTGGCTCGGCCGGGAAGGACCGCTGGCGGAGCTGGACCCGGTCGCCGTCC
GCGAACAGCGCGTGCCGTATCTGCAGATCCTGACCAGCAGGACCTTCTTGGGTTGCGTGGCGGCGACCTTCGGCGCCTAC
TGGGCGCTGTCGCTCGGATTGACCTGGTTCACGCCGTTCCTGATCAAGGGCCTCGGTTTCTCGCAGGCGCAGGCCGGCTT
CATCTCGATCCTGCCGTGGATCTTCGGCGCATGCGTGGTGCTGACGACGGGCTTCGCATCGCAGATGCTGATGGCGCGCG
GCGTGTCCACGCGCCTGGCGCGCGGTGTGCTCGGTGCGACGCCGCTGGTGATCGGCGGGGCGCTGATGGCCGCGATGCCG
CATGTGGACGGGGCGTCGGCCAAGATCGCGCTGGTCGTGGTCGGATCAGGCCTGTGCGGCTCGATCTACGTCGTCTGCCC
GCCGATGATCGGCGAGTTCACGCCGGTCGCGCAGCGTGGCGCCGTCATCTCGATCTACGGTGCCCTGTACACGCTGGCCG
GCATCATCGCGCCGGTCGTGATGGGCAAGATGATCCAGGCTTCCGGCAGCATGCTCGAAGGCTACATGTCCGGCTTCACC
ATCAACGCGGTCATCATGGTGATTTCCGGCCTGCTCGGACTGGCGCTGCTCTGGCCGAACACAGAACGCGCGCGCCTGCA
GGTGGATGAGGCGGTCGCGCCGGAATTTGCGTGA

Upstream 100 bases:

>100_bases
GGCTTAGTGCGCGATCGGGTTGCGCGCAGCGGCGCTTCGTGGGTAGCATCGACAAAACGCCCGAAGCACAGAGGCGGATC
AAAACAAACAACGGGGGTGG

Downstream 100 bases:

>100_bases
GGAGTGCGCGCCATCTATTCGGCGTCGTGCCGGCCTTGCGCAGGGACCCATAGCCACCGTCGATCGTGGCTGGGCGGCCT
CGATCGACCAAGGTGCCCCA

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MMAAPTTLKSNARASTASTPKGAWRITFLLFLFMLVNFADKIVVGLAGVPIMTELNLSAEQFGLLGSSFFLLFSLAAIVV
GFIVNKVPTRWVLLVLALVWAVAQFPMVGTVGFTTLLICRIILGAGEGPAASVAVHAIYKWFPDEKRAMPTAILSQGSAF
GVILAVPALNWVIVNHGWHYAFGALGVVGLMWSAAWLWLGREGPLAELDPVAVREQRVPYLQILTSRTFLGCVAATFGAY
WALSLGLTWFTPFLIKGLGFSQAQAGFISILPWIFGACVVLTTGFASQMLMARGVSTRLARGVLGATPLVIGGALMAAMP
HVDGASAKIALVVVGSGLCGSIYVVCPPMIGEFTPVAQRGAVISIYGALYTLAGIIAPVVMGKMIQASGSMLEGYMSGFT
INAVIMVISGLLGLALLWPNTERARLQVDEAVAPEFA

Sequences:

>Translated_437_residues
MMAAPTTLKSNARASTASTPKGAWRITFLLFLFMLVNFADKIVVGLAGVPIMTELNLSAEQFGLLGSSFFLLFSLAAIVV
GFIVNKVPTRWVLLVLALVWAVAQFPMVGTVGFTTLLICRIILGAGEGPAASVAVHAIYKWFPDEKRAMPTAILSQGSAF
GVILAVPALNWVIVNHGWHYAFGALGVVGLMWSAAWLWLGREGPLAELDPVAVREQRVPYLQILTSRTFLGCVAATFGAY
WALSLGLTWFTPFLIKGLGFSQAQAGFISILPWIFGACVVLTTGFASQMLMARGVSTRLARGVLGATPLVIGGALMAAMP
HVDGASAKIALVVVGSGLCGSIYVVCPPMIGEFTPVAQRGAVISIYGALYTLAGIIAPVVMGKMIQASGSMLEGYMSGFT
INAVIMVISGLLGLALLWPNTERARLQVDEAVAPEFA
>Mature_437_residues
MMAAPTTLKSNARASTASTPKGAWRITFLLFLFMLVNFADKIVVGLAGVPIMTELNLSAEQFGLLGSSFFLLFSLAAIVV
GFIVNKVPTRWVLLVLALVWAVAQFPMVGTVGFTTLLICRIILGAGEGPAASVAVHAIYKWFPDEKRAMPTAILSQGSAF
GVILAVPALNWVIVNHGWHYAFGALGVVGLMWSAAWLWLGREGPLAELDPVAVREQRVPYLQILTSRTFLGCVAATFGAY
WALSLGLTWFTPFLIKGLGFSQAQAGFISILPWIFGACVVLTTGFASQMLMARGVSTRLARGVLGATPLVIGGALMAAMP
HVDGASAKIALVVVGSGLCGSIYVVCPPMIGEFTPVAQRGAVISIYGALYTLAGIIAPVVMGKMIQASGSMLEGYMSGFT
INAVIMVISGLLGLALLWPNTERARLQVDEAVAPEFA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=345, Percent_Identity=23.4782608695652, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI9945322, Length=360, Percent_Identity=23.0555555555556, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI21322234, Length=383, Percent_Identity=24.0208877284595, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI9966811, Length=360, Percent_Identity=21.6666666666667, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082320, Length=385, Percent_Identity=23.3766233766234, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789515, Length=407, Percent_Identity=24.0786240786241, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI2367379, Length=289, Percent_Identity=26.9896193771626, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789152, Length=442, Percent_Identity=21.9457013574661, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI2367193, Length=283, Percent_Identity=23.321554770318, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554962, Length=335, Percent_Identity=22.9850746268657, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648416, Length=281, Percent_Identity=24.9110320284698, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356189, Length=281, Percent_Identity=24.9110320284698, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19922400, Length=400, Percent_Identity=25.5, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24654215, Length=400, Percent_Identity=25.5, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI62484226, Length=352, Percent_Identity=25.5681818181818, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24583789, Length=371, Percent_Identity=25.6064690026954, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24584153, Length=364, Percent_Identity=21.978021978022, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24639764, Length=354, Percent_Identity=23.1638418079096, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46187; Mature: 46187

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAAPTTLKSNARASTASTPKGAWRITFLLFLFMLVNFADKIVVGLAGVPIMTELNLSAE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHH
QFGLLGSSFFLLFSLAAIVVGFIVNKVPTRWVLLVLALVWAVAQFPMVGTVGFTTLLICR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IILGAGEGPAASVAVHAIYKWFPDEKRAMPTAILSQGSAFGVILAVPALNWVIVNHGWHY
HHHCCCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHCCCCCEEEEEECCCEEEEEECCCHH
AFGALGVVGLMWSAAWLWLGREGPLAELDPVAVREQRVPYLQILTSRTFLGCVAATFGAY
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
WALSLGLTWFTPFLIKGLGFSQAQAGFISILPWIFGACVVLTTGFASQMLMARGVSTRLA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
RGVLGATPLVIGGALMAAMPHVDGASAKIALVVVGSGLCGSIYVVCPPMIGEFTPVAQRG
HHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEECCCHHCCCCCHHHCC
AVISIYGALYTLAGIIAPVVMGKMIQASGSMLEGYMSGFTINAVIMVISGLLGLALLWPN
CEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
TERARLQVDEAVAPEFA
CCHHHEEEHHHCCCCCC
>Mature Secondary Structure
MMAAPTTLKSNARASTASTPKGAWRITFLLFLFMLVNFADKIVVGLAGVPIMTELNLSAE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHH
QFGLLGSSFFLLFSLAAIVVGFIVNKVPTRWVLLVLALVWAVAQFPMVGTVGFTTLLICR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IILGAGEGPAASVAVHAIYKWFPDEKRAMPTAILSQGSAFGVILAVPALNWVIVNHGWHY
HHHCCCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHCCCCCEEEEEECCCEEEEEECCCHH
AFGALGVVGLMWSAAWLWLGREGPLAELDPVAVREQRVPYLQILTSRTFLGCVAATFGAY
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
WALSLGLTWFTPFLIKGLGFSQAQAGFISILPWIFGACVVLTTGFASQMLMARGVSTRLA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
RGVLGATPLVIGGALMAAMPHVDGASAKIALVVVGSGLCGSIYVVCPPMIGEFTPVAQRG
HHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEECCCHHCCCCCHHHCC
AVISIYGALYTLAGIIAPVVMGKMIQASGSMLEGYMSGFTINAVIMVISGLLGLALLWPN
CEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
TERARLQVDEAVAPEFA
CCHHHEEEHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]