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The map label for this gene is lepB1 [H]

Identifier: 146343481

GI number: 146343481

Start: 6969845

End: 6970636

Strand: Direct

Name: lepB1 [H]

Synonym: BRADO6713

Alternate gene names: 146343481

Gene position: 6969845-6970636 (Clockwise)

Preceding gene: 146343480

Following gene: 146343482

Centisome position: 93.47

GC content: 67.17

Gene sequence:

>792_bases
ATGAGCCTCGACAAGATGTCCACGAGCAAGGTCAGCACCAAAGCTCCGCGCAAGGAAACGACGTGGGGCGGACAGATTGC
CCAGCTCGCCGCCGTCGTCGCGGTCGTCTTCCTTGCCAAGGGCGCGATCGCCGAGCCGTTCTATGTGCCCTCCGGCTCGA
TGGAGCCGACGCTCCTGATCGGCGATGCGCTGCTCGCCTCGAAATTCCCCTATGGCTACGGCACCTCGTCGCTGCCGATG
CAGATCACGCTGCCTGAGACGGGACGGCTGTTCGGCGAAACGCCGAAGCGCGGCGACGTCGTCGTGTTCCGCTGGCCGGG
CGACACCTCCCAGGCCTGGGTCAAGCGCGTCGTCGGCCTGCCGGGCGACCGCATCCAGATGCGCCAGGGCCAGCTCTACA
TCAACGGCCAGGCCGCGCAGCTGAAGCCGGACGGCATCGGCGACGCCGAGGACGACACCGGCCGCAACGAGCCGGCCTAT
CGCTATATCGAGACGCTGCCGAACGGCGTCTCGCATCTGATCTTCAAGATGCGCGACAACGGCCGGCTCGACAACACGCC
CGAGGTGACGGTGCCGCCGGGCAAGCTGTTCGTGCTCGGTGATAACAGAGACAACTCCGCCGACAGCCGAGTGTCGCTGC
GCGATGGCGGCGTCGGCCTGCTGCCGATCGACAATCTGGTCGGCCGCGCCGACGCCGTGGTCGGCTCCTGGGATCTCGGC
TTCAAGAACCAGCCGGTCTGGGCCTGGCTGTCCGGATTCCGGCTCGATCGGTTCTTCACCGCGGTGCGCTGA

Upstream 100 bases:

>100_bases
CCGGCATCGGCACCTGCGGCAAGAACGGCCAGGGCGTGCCGGTCGGCGTGGGACAGCCGACGCTTCGCATGGATCGCATC
ACGGTAGGAGGCACGGGCCG

Downstream 100 bases:

>100_bases
GCGAGAGACGGCGTCTTCCGCAGCGTCATTGCGAGCGCGAGCGAGACAATCCAGGCTGCCGCTGCCACATCGGCCTGGAT
CGCTTATGCAGACAGCGCTC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSLDKMSTSKVSTKAPRKETTWGGQIAQLAAVVAVVFLAKGAIAEPFYVPSGSMEPTLLIGDALLASKFPYGYGTSSLPM
QITLPETGRLFGETPKRGDVVVFRWPGDTSQAWVKRVVGLPGDRIQMRQGQLYINGQAAQLKPDGIGDAEDDTGRNEPAY
RYIETLPNGVSHLIFKMRDNGRLDNTPEVTVPPGKLFVLGDNRDNSADSRVSLRDGGVGLLPIDNLVGRADAVVGSWDLG
FKNQPVWAWLSGFRLDRFFTAVR

Sequences:

>Translated_263_residues
MSLDKMSTSKVSTKAPRKETTWGGQIAQLAAVVAVVFLAKGAIAEPFYVPSGSMEPTLLIGDALLASKFPYGYGTSSLPM
QITLPETGRLFGETPKRGDVVVFRWPGDTSQAWVKRVVGLPGDRIQMRQGQLYINGQAAQLKPDGIGDAEDDTGRNEPAY
RYIETLPNGVSHLIFKMRDNGRLDNTPEVTVPPGKLFVLGDNRDNSADSRVSLRDGGVGLLPIDNLVGRADAVVGSWDLG
FKNQPVWAWLSGFRLDRFFTAVR
>Mature_262_residues
SLDKMSTSKVSTKAPRKETTWGGQIAQLAAVVAVVFLAKGAIAEPFYVPSGSMEPTLLIGDALLASKFPYGYGTSSLPMQ
ITLPETGRLFGETPKRGDVVVFRWPGDTSQAWVKRVVGLPGDRIQMRQGQLYINGQAAQLKPDGIGDAEDDTGRNEPAYR
YIETLPNGVSHLIFKMRDNGRLDNTPEVTVPPGKLFVLGDNRDNSADSRVSLRDGGVGLLPIDNLVGRADAVVGSWDLGF
KNQPVWAWLSGFRLDRFFTAVR

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=301, Percent_Identity=34.8837209302326, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28639; Mature: 28508

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDKMSTSKVSTKAPRKETTWGGQIAQLAAVVAVVFLAKGAIAEPFYVPSGSMEPTLLI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCEEEE
GDALLASKFPYGYGTSSLPMQITLPETGRLFGETPKRGDVVVFRWPGDTSQAWVKRVVGL
CCHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCC
PGDRIQMRQGQLYINGQAAQLKPDGIGDAEDDTGRNEPAYRYIETLPNGVSHLIFKMRDN
CCCEEEEECCEEEECCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHEEEEEECCC
GRLDNTPEVTVPPGKLFVLGDNRDNSADSRVSLRDGGVGLLPIDNLVGRADAVVGSWDLG
CCCCCCCEEEECCCEEEEEECCCCCCCCCEEEECCCCEEEEEHHHHHCCHHHEEECCCCC
FKNQPVWAWLSGFRLDRFFTAVR
CCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLDKMSTSKVSTKAPRKETTWGGQIAQLAAVVAVVFLAKGAIAEPFYVPSGSMEPTLLI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCEEEE
GDALLASKFPYGYGTSSLPMQITLPETGRLFGETPKRGDVVVFRWPGDTSQAWVKRVVGL
CCHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCC
PGDRIQMRQGQLYINGQAAQLKPDGIGDAEDDTGRNEPAYRYIETLPNGVSHLIFKMRDN
CCCEEEEECCEEEECCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHEEEEEECCC
GRLDNTPEVTVPPGKLFVLGDNRDNSADSRVSLRDGGVGLLPIDNLVGRADAVVGSWDLG
CCCCCCCEEEECCCEEEEEECCCCCCCCCEEEECCCCEEEEEHHHHHCCHHHEEECCCCC
FKNQPVWAWLSGFRLDRFFTAVR
CCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA