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The map label for this gene is mcpA [H]

Identifier: 146343441

GI number: 146343441

Start: 6928394

End: 6930532

Strand: Direct

Name: mcpA [H]

Synonym: BRADO6670

Alternate gene names: 146343441

Gene position: 6928394-6930532 (Clockwise)

Preceding gene: 146343440

Following gene: 146343442

Centisome position: 92.92

GC content: 67.98

Gene sequence:

>2139_bases
ATGGCGGGTCGGTTCAGCTTCAGCAGAATGCTCGGAGTCCTGCGTCCCAGATGGGGCGTCCGTGGCAGCCTGTTCGCGGC
GTTTGCGGTGATCGCCGGCATGGCGATCGCGATCAGCGTCGGCGCCGGGCTGATGCTGCGCCACATCGGCGGCACCATGG
TCGAGCTGTCCGGCAGCGACATTCCCCGCCTCACCGCGAGCCTGCAGCTGCTGGCGCAGAGCTCGAGTCTCGCCAGCCTG
GGTCCGGCGCTATTGGGCTCGCAGAGCGAGGACGCGCTCAACGATCGCCTCAAGAAGATGCAGGAGATCCAGAAGGCCAC
GCAGCAGCGCCTTGCCGAAATCAGCGCACTCGGCGCCGAAAAGAGCGTGGTCGCGCCGCTCGCCGAGACGATCAAGAACA
TCAACGAGGCCAATCAGAGCCTGGTGTCGGCCGCGCGCGAGCGCCTCGCCGTCGCAGCCATGCACAATCAGCAGTACGAC
GCGCTGCGCAAGGCGCAGGAGGAGTTCACCAAGGCGGCGAACGAGCCGATGCTCGACGCCCAGACGCAGCTCAACGCCGT
GCTAGGCGCCGCCGAGGTCTCTGCGGACGACGCCACCGCGGCGGCGCGCTTCGTCGAGCAGCTCGGCAACGTGATCGCAT
CAGGCAATCTGATCGTCGCGCAGATGGCGGCCGCGCTCTCGGCCAATGACAGCGACACGCTGGAGTCTGTCGAGCGACAG
TTCAAGGATTCGCTGGCCCAGCTAAAGTCGAACCTCGAGCTGCTGCCGAACGGACGCAGCACCAAGGCGATCAACGACGC
GGCGATGAAGCTCGCCGCGCTCGGCGAGGGCAAGAGCCGCGTGTTCAAGACCCGCGAAAAAGAGCTCGACGCGAACGATT
ACGGCCAGACCGTGCTGGAGGAGACGCGCAAGCTCAATGTCGGTCTCGACATCAGCGTCCAGCAGCTCGTCGAGGGCGTC
CGCAAATCGACCGAAGGCGCCACCGTCACGGCCGGCCGCGAGATCGAGTTCGGGACGTTCGGCATGGTTGGCGCCGGCGC
GGCGACACTGCTCGGTTCGATTCTGTTCGTCTGGCTCTATGTCGGCGGCAACATCCTGCGCCGGATCAAGCGGCTGCAGC
AGGCGATGCAGAACCTCTCGAGCGGCGACCTGGCGACGGAGATCGCGGCCTCGAAGCAGCGGGACGAGATCGGCGCGATG
GTCGACACCCTGCAGGTGTTCCGCGACAACATGATCCAGGCCCGCACGCTCGCCGCCGAGCAGGAGCGCGAGAACGCCGC
CAAGGCGGAGCGCGCCACGCGCATGGAGGCGCGCATTGCCGAGTTCGAGGCGACGGTGCGCAGCGCGCTGGCCAATCTGC
AGAGCTCGGCGACGGCGATGCAGACGACGGCGCAGAGCATGTCCCAGACCGCCGATGAGTCCAACTCGCTGGTCAGCGCG
GTCGCCGCGGCGGCCGAGGAGACCTCGGTCAACGTGCAGACCGTGTCCGCCGGCACCGAGCAGCTGTCGTCGTCGATCGC
CGAGATCGGCCGCCAGGTCGTGACCTCGGCGCAGATCGCCAAGAAAGCCGTCGAGGAGGCCGGCGCCACTGACTCGACGA
TGCAGGGCCTCGCCGACAATGCGAGCCGCGTCAGTGTCGTCGTCGACCTCATTCAGGCGATCGCCTCGCAGACCAACCTG
CTGGCGCTCAACGCCACGATCGAGGCGGCCCGTGCGGGCGAGGCCGGCCGCGGCTTCGCGGTCGTGGCCCAGGAAGTGAA
GAGTCTCGCCAGTCAGACCGCCAAGGCCACCGACGAAATCCGCGCCCAGATCGCCAGCATGCAGCAGGTCGCGTCGTCGG
CGGTTGCGGCGATCCGCAACATCGGCGGGACCATTGCCGAGATCGACAACGTCACGACCGCGATCGCCGCGGCCGTGGAG
CAGCAGGGCACCGCCACGCACGAGATGGCCCGCAACATCCAGCAGGCGGCTTCGGGCACCAGCGAGGTCTCGCATAACAT
CACCGGCGTCTCCAGCGCCTCGGCCCAGGCCGGCACCTCGGCGAACGAGGTGCTGACCGCCTCGGAGGCGCTGCGCCGGG
AGGCCGAGACCTTGCGCGCGGAAGTGGACGCCTTCCTGATCAACATCAGGGCGGCGTAG

Upstream 100 bases:

>100_bases
ATCAGCAGGAACCGCGTAATTTCCCTGATTGTTAACTCACGACCGCGATAGTGCTCGCACAAATATCAGCTCAAAGTAGC
ACGATCGAGGGAAACGAGAC

Downstream 100 bases:

>100_bases
CGACAGCTGCTCCCAGCGTCATTCCGGGGCAATGGCCGATGCGCAACGCGCATTGGCGATTGAACCCGGAATCTCGAACT
GGTGAGCGCAAGACAATCTC

Product: putative methyl-accepting chemotaxis receptor/sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MAGRFSFSRMLGVLRPRWGVRGSLFAAFAVIAGMAIAISVGAGLMLRHIGGTMVELSGSDIPRLTASLQLLAQSSSLASL
GPALLGSQSEDALNDRLKKMQEIQKATQQRLAEISALGAEKSVVAPLAETIKNINEANQSLVSAARERLAVAAMHNQQYD
ALRKAQEEFTKAANEPMLDAQTQLNAVLGAAEVSADDATAAARFVEQLGNVIASGNLIVAQMAAALSANDSDTLESVERQ
FKDSLAQLKSNLELLPNGRSTKAINDAAMKLAALGEGKSRVFKTREKELDANDYGQTVLEETRKLNVGLDISVQQLVEGV
RKSTEGATVTAGREIEFGTFGMVGAGAATLLGSILFVWLYVGGNILRRIKRLQQAMQNLSSGDLATEIAASKQRDEIGAM
VDTLQVFRDNMIQARTLAAEQERENAAKAERATRMEARIAEFEATVRSALANLQSSATAMQTTAQSMSQTADESNSLVSA
VAAAAEETSVNVQTVSAGTEQLSSSIAEIGRQVVTSAQIAKKAVEEAGATDSTMQGLADNASRVSVVVDLIQAIASQTNL
LALNATIEAARAGEAGRGFAVVAQEVKSLASQTAKATDEIRAQIASMQQVASSAVAAIRNIGGTIAEIDNVTTAIAAAVE
QQGTATHEMARNIQQAASGTSEVSHNITGVSSASAQAGTSANEVLTASEALRREAETLRAEVDAFLINIRAA

Sequences:

>Translated_712_residues
MAGRFSFSRMLGVLRPRWGVRGSLFAAFAVIAGMAIAISVGAGLMLRHIGGTMVELSGSDIPRLTASLQLLAQSSSLASL
GPALLGSQSEDALNDRLKKMQEIQKATQQRLAEISALGAEKSVVAPLAETIKNINEANQSLVSAARERLAVAAMHNQQYD
ALRKAQEEFTKAANEPMLDAQTQLNAVLGAAEVSADDATAAARFVEQLGNVIASGNLIVAQMAAALSANDSDTLESVERQ
FKDSLAQLKSNLELLPNGRSTKAINDAAMKLAALGEGKSRVFKTREKELDANDYGQTVLEETRKLNVGLDISVQQLVEGV
RKSTEGATVTAGREIEFGTFGMVGAGAATLLGSILFVWLYVGGNILRRIKRLQQAMQNLSSGDLATEIAASKQRDEIGAM
VDTLQVFRDNMIQARTLAAEQERENAAKAERATRMEARIAEFEATVRSALANLQSSATAMQTTAQSMSQTADESNSLVSA
VAAAAEETSVNVQTVSAGTEQLSSSIAEIGRQVVTSAQIAKKAVEEAGATDSTMQGLADNASRVSVVVDLIQAIASQTNL
LALNATIEAARAGEAGRGFAVVAQEVKSLASQTAKATDEIRAQIASMQQVASSAVAAIRNIGGTIAEIDNVTTAIAAAVE
QQGTATHEMARNIQQAASGTSEVSHNITGVSSASAQAGTSANEVLTASEALRREAETLRAEVDAFLINIRAA
>Mature_711_residues
AGRFSFSRMLGVLRPRWGVRGSLFAAFAVIAGMAIAISVGAGLMLRHIGGTMVELSGSDIPRLTASLQLLAQSSSLASLG
PALLGSQSEDALNDRLKKMQEIQKATQQRLAEISALGAEKSVVAPLAETIKNINEANQSLVSAARERLAVAAMHNQQYDA
LRKAQEEFTKAANEPMLDAQTQLNAVLGAAEVSADDATAAARFVEQLGNVIASGNLIVAQMAAALSANDSDTLESVERQF
KDSLAQLKSNLELLPNGRSTKAINDAAMKLAALGEGKSRVFKTREKELDANDYGQTVLEETRKLNVGLDISVQQLVEGVR
KSTEGATVTAGREIEFGTFGMVGAGAATLLGSILFVWLYVGGNILRRIKRLQQAMQNLSSGDLATEIAASKQRDEIGAMV
DTLQVFRDNMIQARTLAAEQERENAAKAERATRMEARIAEFEATVRSALANLQSSATAMQTTAQSMSQTADESNSLVSAV
AAAAEETSVNVQTVSAGTEQLSSSIAEIGRQVVTSAQIAKKAVEEAGATDSTMQGLADNASRVSVVVDLIQAIASQTNLL
ALNATIEAARAGEAGRGFAVVAQEVKSLASQTAKATDEIRAQIASMQQVASSAVAAIRNIGGTIAEIDNVTTAIAAAVEQ
QGTATHEMARNIQQAASGTSEVSHNITGVSSASAQAGTSANEVLTASEALRREAETLRAEVDAFLINIRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=190, Percent_Identity=38.4210526315789, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789453, Length=195, Percent_Identity=33.8461538461538, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI2367378, Length=314, Percent_Identity=24.5222929936306, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788194, Length=236, Percent_Identity=31.3559322033898, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1787690, Length=234, Percent_Identity=30.7692307692308, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 74601; Mature: 74470

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRFSFSRMLGVLRPRWGVRGSLFAAFAVIAGMAIAISVGAGLMLRHIGGTMVELSGSD
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
IPRLTASLQLLAQSSSLASLGPALLGSQSEDALNDRLKKMQEIQKATQQRLAEISALGAE
CHHHHHHHHHHHHHCCHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KSVVAPLAETIKNINEANQSLVSAARERLAVAAMHNQQYDALRKAQEEFTKAANEPMLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QTQLNAVLGAAEVSADDATAAARFVEQLGNVIASGNLIVAQMAAALSANDSDTLESVERQ
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHH
FKDSLAQLKSNLELLPNGRSTKAINDAAMKLAALGEGKSRVFKTREKELDANDYGQTVLE
HHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHH
ETRKLNVGLDISVQQLVEGVRKSTEGATVTAGREIEFGTFGMVGAGAATLLGSILFVWLY
HHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCEECCCCCCCHHCCHHHHHHHHHHHHHH
VGGNILRRIKRLQQAMQNLSSGDLATEIAASKQRDEIGAMVDTLQVFRDNMIQARTLAAE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QERENAAKAERATRMEARIAEFEATVRSALANLQSSATAMQTTAQSMSQTADESNSLVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAAAEETSVNVQTVSAGTEQLSSSIAEIGRQVVTSAQIAKKAVEEAGATDSTMQGLADN
HHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
ASRVSVVVDLIQAIASQTNLLALNATIEAARAGEAGRGFAVVAQEVKSLASQTAKATDEI
HHHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAQIASMQQVASSAVAAIRNIGGTIAEIDNVTTAIAAAVEQQGTATHEMARNIQQAASGT
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCH
SEVSHNITGVSSASAQAGTSANEVLTASEALRREAETLRAEVDAFLINIRAA
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
AGRFSFSRMLGVLRPRWGVRGSLFAAFAVIAGMAIAISVGAGLMLRHIGGTMVELSGSD
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
IPRLTASLQLLAQSSSLASLGPALLGSQSEDALNDRLKKMQEIQKATQQRLAEISALGAE
CHHHHHHHHHHHHHCCHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KSVVAPLAETIKNINEANQSLVSAARERLAVAAMHNQQYDALRKAQEEFTKAANEPMLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QTQLNAVLGAAEVSADDATAAARFVEQLGNVIASGNLIVAQMAAALSANDSDTLESVERQ
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHH
FKDSLAQLKSNLELLPNGRSTKAINDAAMKLAALGEGKSRVFKTREKELDANDYGQTVLE
HHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHH
ETRKLNVGLDISVQQLVEGVRKSTEGATVTAGREIEFGTFGMVGAGAATLLGSILFVWLY
HHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCEECCCCCCCHHCCHHHHHHHHHHHHHH
VGGNILRRIKRLQQAMQNLSSGDLATEIAASKQRDEIGAMVDTLQVFRDNMIQARTLAAE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QERENAAKAERATRMEARIAEFEATVRSALANLQSSATAMQTTAQSMSQTADESNSLVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAAAEETSVNVQTVSAGTEQLSSSIAEIGRQVVTSAQIAKKAVEEAGATDSTMQGLADN
HHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
ASRVSVVVDLIQAIASQTNLLALNATIEAARAGEAGRGFAVVAQEVKSLASQTAKATDEI
HHHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAQIASMQQVASSAVAAIRNIGGTIAEIDNVTTAIAAAVEQQGTATHEMARNIQQAASGT
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCH
SEVSHNITGVSSASAQAGTSANEVLTASEALRREAETLRAEVDAFLINIRAA
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]